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1.发明申请公开(公告)号：US20110106120A1
公开(公告)日：2011-05-05
申请号：US12863030
申请日：2009-01-16
Applicant: Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlebois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
Inventor： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlebois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
IPC: A61B17/11
CPC classification number: A61M1/125 , A61B5/076 , A61B5/14535 , A61B5/14539 , A61B5/6862 , A61B5/6876 , A61B5/6882 , A61F2/0077 , A61F2/2418 , A61F2/2475 , A61F2/86 , A61F2002/068 , A61F2002/8486 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0071 , A61F2230/008 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/1098 , A61M1/122 , A61M1/3653 , A61M1/3659
Abstract: An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system includes a tubular expandable body defining a lumen therethrough. The tubular expandable body is configured to move between an expanded state to contact the body vessel and a collapsed state for delivery or retrieval. The tubular expandable body is configured to contact the vessel wall along the length of the tubular expandable body in the expanded state when deployed in the body vessel. An intravascular device is held to the exterior side of the tubular expandable body and is configured to contact the vessel wall when the tubular expandable body is in the expanded state and the system is deployed within a body vessel.
Abstract translation: 公开了一种用于将血管内装置附接到身体血管的血管壁的附接系统。 附接系统包括限定通过其中的腔的管状可扩张体。 管状可膨胀体构造成在膨胀状态下与身体容器接触并且用于输送或取出的折叠状态。 管状可膨胀体构造成当展开在身体容器中时，处于膨胀状态的管状可膨胀体的长度的容器壁接触。 血管内装置被保持在管状可膨胀体的外侧，并且构造成当管状可膨胀体处于膨胀状态并且系统部署在体内容器内时与血管壁接触。
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公开(公告)号：US08303648B2
公开(公告)日：2012-11-06
申请号：US11789413
申请日：2007-04-24
Applicant: David D. Grewe , James D. Purdy
Inventor： David D. Grewe , James D. Purdy
CPC classification number: A61F2/2412 , A61F2/2418 , A61F2/2475 , A61F2220/0016 , A61F2220/005 , A61F2220/0058 , A61F2230/0026 , A61F2230/0095 , A61F2250/0068
Abstract: The invention relates to a prosthetic valve for regulating flow through a body lumen and delivering a therapeutic agent into said lumen. In one embodiment, the prosthesis includes a frame having an exterior wall, a hollow interior space, a valve member, and at least one aperture through the exterior wall that permits a controlled amount of therapeutic agent loaded into the hollow interior into the surrounding body lumen following implantation. In another embodiment, the prosthesis includes a frame having a groove, a valve member, and therapeutic agent loaded in the groove.
Abstract translation: 本发明涉及一种用于调节通过体腔的流动并将治疗剂输送到所述内腔中的人造瓣膜。 在一个实施例中，假体包括具有外壁，中空内部空间，阀构件和穿过外壁的至少一个孔的框架，其允许将受控量的治疗剂装载到中空内部进入周围体腔 植入后。 在另一个实施例中，假体包括具有凹槽，阀构件和装载在凹槽中的治疗剂的框架。
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公开(公告)号：US20090149938A1
公开(公告)日：2009-06-11
申请号：US12330833
申请日：2008-12-09
Applicant: David D. Grewe , James D. Purdy , Kenneth Haselby , David Brocker
Inventor： David D. Grewe , James D. Purdy , Kenneth Haselby , David Brocker
CPC classification number: A61F2/95 , A61B17/3498 , A61B2017/00292 , A61B2017/00845 , A61M39/0606 , A61M2025/0062 , A61M2039/068
Abstract: A delivery and deployment device comprises a sheath having a proximal end, a distal end, and a lumen disposed therebetween; a dilator having a distal end slidingly disposed within the sheath lumen; a valve assembly comprising a valve housing affixed to the sheath and a valve disposed within the housing between the sheath and the dilator; and a valve lubrication mechanism disposed between the valve and the dilator.
Abstract translation: 递送和展开装置包括具有近端，远端和设置在其间的内腔的护套; 扩张器，其具有滑动地设置在鞘腔内的远端; 阀组件，其包括固定到护套的阀壳体和设置在护套和扩张器之间的壳体内的阀; 以及设置在所述阀和所述扩张器之间的阀润滑机构。
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公开(公告)号：US20080154351A1
公开(公告)日：2008-06-26
申请号：US11850885
申请日：2007-09-06
Applicant: Alan R. Leewood , David D. Grewe , Mark J. Hiatt , Anthony O. Ragheb , William D. Voorhees , Blayne A. Roeder , James D. Purdy
Inventor： Alan R. Leewood , David D. Grewe , Mark J. Hiatt , Anthony O. Ragheb , William D. Voorhees , Blayne A. Roeder , James D. Purdy
CPC classification number: A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/825 , A61F2002/826 , A61F2002/91566 , A61F2002/91575 , A61F2002/9511 , A61F2210/0004 , A61F2220/0075 , A61F2250/0031 , A61F2250/0071
Abstract: Various stent structures are provided with improved axial and torsional flexibility. One type of stent structure includes multiple segmented stent structures connected to each other by biodegradable interconnectors. A delivery system adapted to delivery the multiple segmented stents is also described. Another type of stent structure includes biodegradable connectors that are incorporated into a framework of non-biodegradable interconnecting members that form the support structure of the stent. The biodegradable connectors in both stent structures degrade or are absorbed after the stent is deployed. Stabilizing elements may be provided to the stent structures to supplement the stiffness of the stent with stability during loading and deployment.
Abstract translation: 各种支架结构具有改进的轴向和扭转弹性。 一种类型的支架结构包括通过可生物降解的互连器彼此连接的多个分段的支架结构。 还描述了适于递送多个分段支架的递送系统。 另一种类型的支架结构包括可生物降解的连接器，其被结合到形成支架的支撑结构的不可生物降解的互连构件的框架中。 支架结构中的可生物降解的连接器在支架部署后降解或被吸收。 可以将稳定元件提供给支架结构，以在加载和展开期间具有稳定性补充支架的刚度。
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公开(公告)号：US08858608B2
公开(公告)日：2014-10-14
申请号：US12330833
申请日：2008-12-09
Applicant: David D. Grewe , James D. Purdy , Kenneth Haselby , David Brocker
Inventor： David D. Grewe , James D. Purdy , Kenneth Haselby , David Brocker
CPC classification number: A61F2/95 , A61B17/3498 , A61B2017/00292 , A61B2017/00845 , A61M39/0606 , A61M2025/0062 , A61M2039/068
Abstract: A delivery and deployment device comprises a sheath having a proximal end, a distal end, and a lumen disposed therebetween; a dilator having a distal end slidingly disposed within the sheath lumen; a valve assembly comprising a valve housing affixed to the sheath and a valve disposed within the housing between the sheath and the dilator; and a valve lubrication mechanism disposed between the valve and the dilator.
Abstract translation: 递送和展开装置包括具有近端，远端和设置在其间的内腔的护套; 扩张器，其具有滑动地设置在鞘腔内的远端; 阀组件，其包括固定到护套的阀壳体和设置在护套和扩张器之间的壳体内的阀; 以及设置在所述阀和所述扩张器之间的阀润滑机构。
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Patent Agency Ranking
公开(公告)号：US20110106115A1
公开(公告)日：2011-05-05
申请号：US12863034
申请日：2009-01-16
Applicant: Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlesbois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
Inventor： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlesbois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
IPC: A61B17/11
CPC classification number: A61M1/125 , A61B5/076 , A61B5/14535 , A61B5/14539 , A61B5/6862 , A61B5/6876 , A61B5/6882 , A61F2/0077 , A61F2/2418 , A61F2/2475 , A61F2/86 , A61F2002/068 , A61F2002/8486 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0071 , A61F2230/008 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/1098 , A61M1/122 , A61M1/3653 , A61M1/3659
Abstract: An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system has an intravascular device having a first end and a second end. The intravascular device defines a longitudinal axis along a length thereof. Several struts are connected to one or more ends of the intravascular device. Each strut is configured to move along a strut path relative to the longitudinal axis between an expanded state for engaging the vessel wall and a collapsed state for delivery or retrieval. Each strut has a free end configured to engage the vessel wall in the expanded state.
Abstract translation: 公开了一种用于将血管内装置附接到身体血管的血管壁的附接系统。 附接系统具有具有第一端和第二端的血管内装置。 血管内装置沿其长度限定纵向轴线。 几个支柱连接到血管内装置的一个或多个端部。 每个支柱被构造成在用于接合血管壁的膨胀状态和用于输送或取回的折叠状态之间相对于纵向轴线沿着支柱路径移动。 每个支柱具有构造成在膨胀状态下接合血管壁的自由端。
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公开(公告)号：US08211168B2
公开(公告)日：2012-07-03
申请号：US11708412
申请日：2007-02-20
Applicant: James D. Purdy , David D. Grewe , Kurt Dierking , Lal Ninan , Jichao Sun
Inventor： James D. Purdy , David D. Grewe , Kurt Dierking , Lal Ninan , Jichao Sun
CPC classification number: A61L27/34 , A61L27/3629 , A61L27/3633 , A61L27/48 , A61L27/56 , A61L31/005 , A61L31/10 , A61L31/128 , A61L31/146 , B32B1/08 , B32B5/02 , B32B5/18 , B32B27/065 , B32B27/12 , B32B27/18 , B32B27/205 , B32B27/28 , B32B27/283 , B32B27/40 , B32B2262/0276 , B32B2266/06 , B32B2535/00 , C08F255/00 , C08F283/006 , C08F283/12 , C08F289/00 , C08F291/00 , C08G18/3228 , C08G18/4854 , C08G18/61 , C08G2101/00 , Y10T428/31844
Abstract: This invention is directed to graft materials for implanting, transplanting, replacing, or repairing a part of a patient and to methods of making the graft materials. The present invention is also directed to stent grafts and endoluminal prostheses formed of the graft materials. More specifically, the present invention is a graft material which includes porous polymeric sheet, extracellular matrix material (ECM) disposed on at least a portion of the porous polymeric sheet and at least one polymer layer disposed on at least a portion of the ECM. The ECM may be in a gel form. The polymeric sheet and the polymer layer may be made from foam material and may comprise a polyurethane urea and a surface modifying agent such as siloxane.
Abstract translation: 本发明涉及用于植入，移植，替换或修复患者的一部分的移植材料以及制备移植材料的方法。 本发明还涉及由移植材料形成的支架移植物和腔内假体。 更具体地，本发明是一种移植材料，其包括多孔聚合物片材，设置在多孔聚合物片材的至少一部分上的细胞外基质材料（ECM）和设置在ECM的至少一部分上的至少一个聚合物层。 ECM可以是凝胶形式。 聚合物片材和聚合物层可以由泡沫材料制成，并且可以包含聚氨酯脲和表面改性剂如硅氧烷。
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公开(公告)号：US20110160844A1
公开(公告)日：2011-06-30
申请号：US12863038
申请日：2009-01-16
Applicant: Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlebois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
Inventor： Kenneth Haselby , Brian D. Choules , Blayne A. Roeder , Richard B. Sisken , David Eric Orr , James D. Purdy , Steven J. Charlebois , David D. Grewe , Neal E. Fearnot , Alan R. Leewood
IPC: A61F2/84
CPC classification number: A61M1/125 , A61B5/076 , A61B5/14535 , A61B5/14539 , A61B5/6862 , A61B5/6876 , A61B5/6882 , A61F2/0077 , A61F2/2418 , A61F2/2475 , A61F2/86 , A61F2002/068 , A61F2002/8486 , A61F2220/0016 , A61F2220/0058 , A61F2220/0075 , A61F2230/005 , A61F2230/0071 , A61F2230/008 , A61M1/1006 , A61M1/1008 , A61M1/101 , A61M1/1098 , A61M1/122 , A61M1/3653 , A61M1/3659
Abstract: An attachment system for attaching an intravascular device to a vessel wall of a body vessel is disclosed. The attachment system includes an intravascular device and biological attachment material connected to the intravascular device. The biological attachment material is configured to attach the intravascular device to the vessel wall.
Abstract translation: 公开了一种用于将血管内装置附接到身体血管的血管壁的附接系统。 附着系统包括连接到血管内装置的血管内装置和生物附着材料。 生物附着材料构造成将血管内装置附接到血管壁。
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9.发明授权Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists 有权用于局部递送血管紧张素II 2型受体拮抗剂的医疗装置和方法公开(公告)号：US07828840B2
公开(公告)日：2010-11-09
申请号：US12291593
申请日：2008-11-12
Applicant: David Paul Biggs , David D. Grewe , Anthony O. Ragheb , Patrick H. Ruane
Inventor： David Paul Biggs , David D. Grewe , Anthony O. Ragheb , Patrick H. Ruane
CPC classification number: A61F2/86 , A61F2210/0076 , A61F2220/0016 , A61F2220/0075 , A61F2230/005 , A61F2230/0054 , A61F2250/0067 , A61F2250/0068
Abstract: This invention relates to medical devices and an angiotensin II type 2 (AT2) receptor antagonist compound, the medical device being adapted to release the AT2 receptor antagonist compound within a body of a patient. This invention also relates to medical devices and methods of treatment of disease, such as aneurysms and aortic dissection. Medical devices may include coated stents, grafts, stent grafts, balloons and catheters.
Abstract translation: 本发明涉及医疗装置和血管紧张素II型2型（AT2）受体拮抗剂化合物，该医疗装置适于释放患者体内的AT2受体拮抗剂化合物。 本发明还涉及医疗装置和治疗疾病的方法，例如动脉瘤和主动脉夹层。 医疗装置可以包括涂覆支架，移植物，支架移植物，气囊和导管。
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公开(公告)号：US07780717B2
公开(公告)日：2010-08-24
申请号：US11789840
申请日：2007-04-26
Applicant: Werner Dieter Ducke , David Ernest Hartley , David D. Grewe
Inventor： Werner Dieter Ducke , David Ernest Hartley , David D. Grewe
IPC: A61F2/06
CPC classification number: A61F2/95 , A61F2002/9517 , A61F2250/0065 , A61M25/0136
Abstract: A stent graft introducer actuation assembly (1) having a fixed handle (3) and at least one sliding handle (5, 7), the sliding handle or handles telescoping within the fixed handle, and a winch arrangement (9) to retract the sliding handle into the fixed handle. There may be provided arrangements to give a mechanical advantage to the winch arrangement.
Abstract translation: 一种具有固定手柄（3）和至少一个滑动手柄（5,7）的支架移植物导引器致动组件（1），所述滑动手柄或手柄在固定手柄内伸缩，以及绞盘装置（9） 处理固定手柄。 可以提供为绞盘装置提供机械优点的布置。
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