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公开(公告)号:US20130240251A1
公开(公告)日:2013-09-19
申请号:US13641000
申请日:2011-04-12
申请人: David Kaplan , Fiorenzo Omenetto , Jason Amsden , Hu Tao , Richard Averitt , Andrew Strikwerda , Xin Zhang , Konstantinos Tsioris
发明人: David Kaplan , Fiorenzo Omenetto , Jason Amsden , Hu Tao , Richard Averitt , Andrew Strikwerda , Xin Zhang , Konstantinos Tsioris
IPC分类号: H05K1/03
摘要: The invention relates to silk electronic components and methods for fabricating the same. The silk electronic components can be used as novel devices, such as implantable bioelectric and/or biophotonic devices, biosensors, surveillance devices, invisible cloaks, electromagnetic concentrators or antennas.
摘要翻译: 本发明涉及丝电子部件及其制造方法。 丝电子部件可以用作可植入生物电离和/或生物光子装置,生物传感器,监视装置,隐形斗篷,电磁集中器或天线的新型装置。
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公开(公告)号:US09603243B2
公开(公告)日:2017-03-21
申请号:US13641000
申请日:2011-04-12
申请人: David Kaplan , Fiorenzo Omenetto , Hu Tao , Richard Averitt , Andrew Strikwerda , Xin Zhang , Konstantinos Tsioris
发明人: David Kaplan , Fiorenzo Omenetto , Hu Tao , Richard Averitt , Andrew Strikwerda , Xin Zhang , Konstantinos Tsioris
摘要: The invention relates to silk electronic components and methods for fabricating the same. The silk electronic components can be used as novel devices, such as implantable bioelectric and/or biophotonic devices, biosensors, surveillance devices, invisible cloaks, electromagnetic concentrators or antennas.
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公开(公告)号:US20130330710A1
公开(公告)日:2013-12-12
申请号:US13813288
申请日:2011-07-30
申请人: Fiorenzo Omenetto , David Kaplan , Jason Amsden , Luca Dal Negro
发明人: Fiorenzo Omenetto , David Kaplan , Jason Amsden , Luca Dal Negro
IPC分类号: G01N21/25
CPC分类号: G01N21/25 , B82Y30/00 , G01N21/4788 , G01N33/54373
摘要: The present disclosure relates to biophotonic sensors. An example of a biophotonic sensor may be an apparatus for analyzing a sample. The apparatus may include a substrate, aperiodic nanostructured protrusions disposed on the substrate, and a silk material deposited between the protrusions.
摘要翻译: 本发明涉及生物光子传感器。 生物光子传感器的实例可以是用于分析样品的装置。 该装置可以包括衬底,设置在衬底上的非周期纳米结构化突起和沉积在突起之间的丝材料。
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公开(公告)号:US08666471B2
公开(公告)日:2014-03-04
申请号:US12892001
申请日:2010-09-28
申请人: John A. Rogers , Dae-Hyeong Kim , Fiorenzo Omenetto , David L. Kaplan , Brian Litt , Jonathan Viventi , Yonggang Huang , Jason Amsden
发明人: John A. Rogers , Dae-Hyeong Kim , Fiorenzo Omenetto , David L. Kaplan , Brian Litt , Jonathan Viventi , Yonggang Huang , Jason Amsden
CPC分类号: A61B5/04 , A61B5/05 , A61B5/6867 , A61B2562/0285 , A61L31/047 , A61L31/148 , A61N1/0529 , A61N1/0551 , B82Y15/00 , H01L2924/0002 , H05K1/0283 , H05K3/20 , H01L2924/00
摘要: Provided herein are implantable biomedical devices, methods of administering implantable biomedical devices, methods of making implantable biomedical devices, and methods of using implantable biomedical devices to actuate a target tissue or sense a parameter associated with the target tissue in a biological environment. Each implantable biomedical device comprises a bioresorbable substrate, an electronic device having a plurality of inorganic semiconductor components supported by the bioresorbable substrate, and a barrier layer encapsulating at least a portion of the inorganic semiconductor components. Upon contact with a biological environment the bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between the implantable biomedical device and the target tissue in the biological environment.
摘要翻译: 本文提供了植入式生物医学装置,可植入生物医学装置的施用方法,制造可植入生物医学装置的方法,以及使用可植入生物医学装置致动靶组织或感测与生物环境中的靶组织相关的参数的方法。 每个可植入的生物医学装置包括生物可再吸收的基底,具有由生物可再吸收的基底支撑的多个无机半导体组分的电子器件,以及封装至少一部分无机半导体组分的阻挡层。 在与生物环境接触时,生物可再吸收底物至少部分吸收,从而在生物环境中建立可植入生物医学装置与靶组织之间的共形接触。
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公开(公告)号:US10562024B2
公开(公告)日:2020-02-18
申请号:US13977233
申请日:2012-01-04
申请人: Fiorenzo Omenetto , David L. Kaplan , Hu Tao
发明人: Fiorenzo Omenetto , David L. Kaplan , Hu Tao
摘要: The present disclosure relates to paper-based substrates and apparatus comprising such substrates. The apparatus may include a patterned conductive structure coupled to the paper-based substrate, wherein the patterned conductive structure responds to electromagnetic radiation.
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公开(公告)号:US20130310908A1
公开(公告)日:2013-11-21
申请号:US13819419
申请日:2011-09-03
申请人: Fiorenzo Omenetto , David L. Kaplan , Hu Tao
发明人: Fiorenzo Omenetto , David L. Kaplan , Hu Tao
CPC分类号: A61N5/0625 , A61F7/03 , A61L31/005 , A61L31/125 , A61L31/14 , A61L2400/12 , A61N5/062 , H01L35/30 , Y10T428/268 , Y10T428/2927
摘要: Provided herein are silk fibroin-based photothermal elements and uses thereof. The silk fibroin-based photothermal elements comprise a plurality of plasmonic nanoparticle distributed in a silk fibroin matrix, and can generate heat when the plasmonic nanoparticles are exposed to electromagnetic radiation. The silk fibroin-based photothermal elements can be adapted to be conformable and biodegradable, and can further be integrated with various electronic components, such as a thermo-electric device for conversion of heat into electricity. The invention is useful for various in vivo applications, such as photothermal therapy, controlled drug-delivery devices or wireless powering of implanted micro-devices.
摘要翻译: 本文提供的是丝素蛋白基光热元件及其用途。 基于丝素蛋白的光热元件包括分布在丝素蛋白基质中的多个等离子体激元纳米颗粒,当等离子体激元纳米粒子暴露于电磁辐射时可产生热量。 丝素蛋白的光热元件可以适应和可生物降解,并且可以进一步与各种电子部件集成,例如用于将热量转换成电的热电装置。 本发明可用于各种体内应用,例如光热治疗,受控药物递送装置或植入的微器件的无线供电。
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公开(公告)号:US09517357B2
公开(公告)日:2016-12-13
申请号:US13819419
申请日:2011-09-03
申请人: Fiorenzo Omenetto , David L. Kaplan , Hu Tao
发明人: Fiorenzo Omenetto , David L. Kaplan , Hu Tao
CPC分类号: A61N5/0625 , A61F7/03 , A61L31/005 , A61L31/125 , A61L31/14 , A61L2400/12 , A61N5/062 , H01L35/30 , Y10T428/268 , Y10T428/2927
摘要: Provided herein are silk fibroin-based photothermal elements and uses thereof. The silk fibroin-based photothermal elements comprise a plurality of plasmonic nanoparticle distributed in a silk fibroin matrix, and can generate heat when the plasmonic nanoparticles are exposed to electromagnetic radiation. The silk fibroin-based photothermal elements can be adapted to be conformable and biodegradable, and can further be integrated with various electronic components, such as a thermo-electric device for conversion of heat into electricity. The invention is useful for various in vivo applications, such as photothermal therapy, controlled drug-delivery devices or wireless powering of implanted micro-devices.
摘要翻译: 本文提供的是丝素蛋白基光热元件及其用途。 基于丝素蛋白的光热元件包括分布在丝素蛋白基质中的多个等离子体激元纳米颗粒,当等离子体激元纳米粒子暴露于电磁辐射时可产生热量。 丝素蛋白的光热元件可以适应和可生物降解,并且可以进一步与各种电子部件集成,例如用于将热量转换成电的热电装置。 本发明可用于各种体内应用,例如光热治疗,受控药物递送装置或植入的微器件的无线供电。
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公开(公告)号:US20140154788A1
公开(公告)日:2014-06-05
申请号:US13977233
申请日:2012-01-04
申请人: Fiorenzo Omenetto , David L. Kaplan , Hu Tao
发明人: Fiorenzo Omenetto , David L. Kaplan , Hu Tao
CPC分类号: B01L3/502707 , C12Q1/54 , G01J1/02 , G01J5/02 , G01N21/3563 , G01N21/3581 , G01N22/00
摘要: The present disclosure relates to paper-based substrates and apparatus comprising such substrates. The apparatus may include a patterned conductive structure coupled to the paper-based substrate, wherein the patterned conductive structure responds to electromagnetic radiation.
摘要翻译: 本公开涉及基于纸的基板和包括这种基板的装置。 该装置可以包括耦合到纸基基板的图案化导电结构,其中图案化导电结构响应于电磁辐射。
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公开(公告)号:US09761789B2
公开(公告)日:2017-09-12
申请号:US13876472
申请日:2011-09-27
申请人: Fiorenzo Omenetto , David Kaplan , Tuna Yucel
发明人: Fiorenzo Omenetto , David Kaplan , Tuna Yucel
IPC分类号: H01L41/193 , H01L21/02 , H01L41/45 , A61N1/365 , A61N1/378 , H01L41/113 , H02N2/18
CPC分类号: H01L41/193 , A61N1/36578 , A61N1/3785 , H01L21/02 , H01L41/1132 , H01L41/45 , H02N2/18
摘要: The invention relates to methods and compositions for preparing silk-based piezoelectric materials and methods for increasing piezoelectricity in silk matrices.
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公开(公告)号:US20140145365A1
公开(公告)日:2014-05-29
申请号:US13876472
申请日:2011-09-27
申请人: Fiorenzo Omenetto , David Kaplan , Tuna Yucel
发明人: Fiorenzo Omenetto , David Kaplan , Tuna Yucel
IPC分类号: H01L41/193 , H01L21/02
CPC分类号: H01L41/193 , A61N1/36578 , A61N1/3785 , H01L21/02 , H01L41/1132 , H01L41/45 , H02N2/18
摘要: The invention relates to methods and compositions for preparing silk-based piezoelectric materials and methods for increasing piezoelectricity in silk matrices.
摘要翻译: 本发明涉及用于制备丝基压电材料的方法和组合物以及用于增加丝基质中的压电性的方法。
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