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1.发明申请公开(公告)号：US20050250178A1
公开(公告)日：2005-11-10
申请号：US10614599
申请日：2003-07-07
Applicant: David Andrew , David Lewin , Diane Pennica , Luca Rastelli , Bruce Tallion
Inventor： David Andrew , David Lewin , Diane Pennica , Luca Rastelli , Bruce Tallion
Abstract: The present invention provides novel polypeptides, termed FCTRX polypeptides, as well as polynucleotides encoding FCTRX polypeptides and antibodies that immunospecifically bind to an FCTRX or a derivative, variant, mutant, or fragment of an FCTRX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FCTRX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.
Abstract translation: 本发明提供了称为FCTRX多肽的新型多肽，以及编码FCTRX多肽的多核苷酸和免疫特异性结合FCTRX或FCTRX多肽，多核苷酸或抗体的衍生物，变体，突变体或片段的抗体。 本发明还提供了FCTRX多肽，多核苷酸和抗体用于检测和治疗广泛的病理状态以及其它用途的方法。
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公开(公告)号：USD685831S1
公开(公告)日：2013-07-09
申请号：US29438684
申请日：2012-11-30
Applicant: Michael Wunnicke , David Lewin
Designer： Michael Wunnicke , David Lewin
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公开(公告)号：US20050100554A1
公开(公告)日：2005-05-12
申请号：US10367057
申请日：2003-02-14
Applicant: Amanda Jackson , Chean Ooi , David Lewin , Scott Cuthill
Inventor： Amanda Jackson , Chean Ooi , David Lewin , Scott Cuthill
IPC: A61K38/00 , A61K39/00 , C07H21/04 , C07K14/025 , C07K14/47 , C07K16/18 , C12P21/04 , G01N33/532 , G01N33/569 , G01N33/574
CPC classification number: C07K14/005 , A61K38/00 , C07K2319/00 , C12N2710/20022 , G01N33/532 , G01N33/56983 , G01N33/57442 , G01N2333/025 , G01N2500/00 , G01N2500/02
Abstract: The invention provides complexes of at least two polypeptides, and methods of using the same. Purified complexes of two polypeptides are provided, including chimeric complexes, and chimeric polypeptides and complexes thereof are also provided, as are nucleic acids encoding chimeric polypeptides and vectors and cells containing the same. Also provided are methods of identifying agents that disrupt polypeptide complexes, methods of identifying complex or polypeptide in a sample, and for removing the same, methods of determining altered expression of a polypeptide in a subject, and methods of treating/preventing disorders involving altered levels of complex or polypeptide.
Abstract translation: 本发明提供至少两种多肽的复合物及其使用方法。 还提供了两种多肽的纯化复合物，包括嵌合复合物，以及嵌合多肽及其复合物，编码嵌合多肽的核酸和含有该多肽的载体和细胞也是如此。 还提供了鉴定破坏多肽复合物的试剂的方法，鉴定样品中复合物或多肽的方法，以及用于除去它们的方法，确定受试者中多肽表达改变的方法，以及治疗/预防涉及改变水平的病症的方法 的复合物或多肽。
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公开(公告)号：US20070207148A1
公开(公告)日：2007-09-06
申请号：US11625085
申请日：2007-01-19
Applicant: David Lewin , Timothy Stewart
Inventor： David Lewin , Timothy Stewart
IPC: A61K38/00 , A61K31/7052 , A61K39/395 , C07H21/04 , C07K14/00 , C07K16/18 , C12N15/00 , C12N5/06 , C12Q1/68
CPC classification number: C07K14/665 , A61K38/00 , A61K2123/00 , C07K14/57554 , C07K14/5759 , C07K14/805 , C12N9/6424 , C12Q1/6883 , C12Q2600/158 , C12Y304/21094
Abstract: The instant invention is concerned with genes associated with obesity. Additionally, the invention provides methods of using the differential expression of these genes associated with obesity to diagnose and treat obesity, as well as to screen for compounds useful for treating obesity.
Abstract translation: 本发明涉及与肥胖相关的基因。 另外，本发明提供了使用与肥胖相关的这些基因的差异表达来诊断和治疗肥胖症以及筛选可用于治疗肥胖症的化合物的方法。
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公开(公告)号：US20050228171A1
公开(公告)日：2005-10-13
申请号：US11146835
申请日：2005-06-07
Applicant: John More , Jacqueline Rott , David Lewin
Inventor： John More , Jacqueline Rott , David Lewin
CPC classification number: C07K14/473 , A61K38/00 , Y10S530/829 , Y10S530/831
Abstract: The invention relates to a method of removing endotoxin from preparation of alpha-1-acid glycoprotein (orosomucoid) by contact with a finely divided non-toxic resin such as fumed silica. The invention also relates to a purification process for alpha-1-acid glycoprotein which includes this depyrogenation step, and to the depyrogenated product and its clinical uses.
Abstract translation: 本发明涉及通过与细碎的无毒树脂如热解法二氧化硅接触来除去内毒素从制备α-1-酸糖蛋白（orosomucoid）的方法。 本发明还涉及包括该去除热解步骤的α-1-酸糖蛋白的纯化方法，以及该脱氢产物及其临床用途。
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Patent Agency Ranking
公开(公告)号：US20050042655A1
公开(公告)日：2005-02-24
申请号：US10886160
申请日：2004-07-06
Applicant: David Lewin , Richard Shimkets , Lawrence Lasky , Bruce Taillon , Steven Gold
Inventor： David Lewin , Richard Shimkets , Lawrence Lasky , Bruce Taillon , Steven Gold
IPC: G01N33/50 , A61K31/711 , A61K38/00 , A61K45/00 , A61P7/06 , A61P35/00 , A61P35/02 , C07K14/47 , C07K14/52 , C07K16/18 , C07K19/00 , C12M1/00 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12N15/12 , C12Q1/02 , C12Q1/68 , G01N33/15 , G01N33/53 , G01N33/566
CPC classification number: C07K14/521
Abstract: Disclosed are novel hematopioetic modulating nucleic acid sequences and polypeptides. Also disclosed are methods in which the nucleic acids and polypeptides are utilized in the detection and treatment of hematopoietic disorders.
Abstract translation: 公开了新的造血调节核酸序列和多肽。 还公开了将核酸和多肽用于造血障碍的检测和治疗中的方法。
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公开(公告)号：US4645090A
公开(公告)日：1987-02-24
申请号：US779219
申请日：1985-09-23
Applicant: David Lewin
Inventor： David Lewin
CPC classification number: A21B3/133
Abstract: A baking utensil which is designed for use in commercial baking operations has a rigid frame for supporting baking pans. The pans themselves have non-stick baking surfaces and are attached to the frame in a manner which permit ready detachment and replacement. Typically, the pans' baking surfaces are coated with PTFE (polytetrafluororethylene).
Abstract translation: 设计用于商业烘烤操作的烘烤用具具有用于支撑烤盘的刚性框架。 平底锅本身具有不粘的烘烤表面，并以允许准备拆卸和更换的方式附接到框架。 通常，锅的烘烤表面涂覆有PTFE（聚四氟乙烯）。
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公开(公告)号：US20210073739A1
公开(公告)日：2021-03-11
申请号：US16948172
申请日：2020-09-06
Applicant: Benjamin Kwitek , David Lewin
Inventor： Benjamin Kwitek , David Lewin
Abstract: A method for workforce talent, tracking and development, that uses a computer for sending information to each of a plurality of applicants for a job. The computer gets information from people making recommendations about whether to hire the applicants. It sends information to the applicants indicating whether or not they have been selected for the job, including an accepted applicant for the job, and multiple other applicants who were not accepted for the job; and after a job has been accepted, using the computer for tracking multiple applicants including at least the accepted applicant for the job, and multiple of the other applicants.
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公开(公告)号：US08152327B2
公开(公告)日：2012-04-10
申请号：US12572910
申请日：2009-10-02
Applicant: David C. Brands , R. Stephen Mulder , David Lewin
Inventor： David C. Brands , R. Stephen Mulder , David Lewin
CPC classification number: F21L4/027 , F21V5/006 , F21V5/04 , F21V7/0091 , F21V14/06 , F21V14/065 , F21Y2115/10 , G02B19/0028 , G02B19/0061 , Y10S362/80
Abstract: A lens for a flashlight or other lighting unit provides for focusing light from a source, such as an LED, to provide a light beam adjustable between a spot beam and a wide beam. The lens includes a lens body with a front face, a rear LED-receiving well, and a side surface extending between the front face and the rear well. The front face includes a central surface surrounded by an annular concave surface. The rear well includes a space for the LED to be adjusted in position. The rear well space is defined by a concavely-curved sidewall and a concavely-curved base. The concave curvature of the sidewall and base may be Bezier curves.
Abstract translation: 用于手电筒或其他照明单元的透镜提供聚焦来自诸如LED的源的光，以提供在点光束和宽光束之间可调节的光束。 透镜包括具有前表面的透镜体，后LED接收孔以及在前表面和后孔之间延伸的侧表面。 前表面包括由环形凹面包围的中心表面。 后井包括用于将LED调节到适当位置的空间。 后井空间由凹曲面的侧壁和凹弯曲的基部限定。 侧壁和底座的凹曲率可以是贝塞尔曲线。
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公开(公告)号：US20070015700A1
公开(公告)日：2007-01-18
申请号：US11333773
申请日：2006-01-17
Applicant: David Lewin , Timothy Stewart
Inventor： David Lewin , Timothy Stewart
IPC: A01K67/027 , C12P21/06 , C07K14/705 , C07K16/28
CPC classification number: C12N9/1205 , C07K14/575
Abstract: Genes are disclosed that are differentially-regulated during feeding and fasting cycles. These genes, and their encoded polypeptides are useful to combat obesity.
Abstract translation: 公开了在进食和空腹循环期间差异调节的基因。 这些基因及其编码的多肽可用于抵抗肥胖症。
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