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    Renewable polymeric lens coating
    4.
    发明授权
    Renewable polymeric lens coating 失效
    可再生聚合物镜片涂层

    公开(公告)号：US08377126B2

    公开(公告)日：2013-02-19

    申请号：US12641422

    申请日：2009-12-18

    申请人： Joseph A. McGee ,  David Paul Vanderbilt ,  Paul L. Valint, Jr.

    发明人： Joseph A. McGee ,  David Paul Vanderbilt ,  Paul L. Valint, Jr.

    IPC分类号： A61F2/16

    CPC分类号： G02B1/043 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/18 ,  A61L2430/16

    摘要： Disclosed are biomedical devices having a hydrophilic coating on a portion of a surface thereof, the biomedical device comprising: (a) a biomedical device obtained from a polymerization product of a monomeric mixture comprising (i) a polymerizable monomer containing a boronic acid moiety and an electron withdrawing moiety; and (ii) a biomedical device-forming comonomer; and (b) a hydrophilic reactive polymer having complementary reactive functionalities along the polymer chain, wherein the complementary reactive functionalities along the polymer chain of the hydrophilic reactive polymer of (b) bind with the boronic acid moieties of the biomedical device of (a), thereby producing a biocompatible coating which can be removed and re-applied to restore the surface properties of the biomedical device to substantially as-new condition. Methods for treating the biomedical device are also disclosed.

    摘要翻译： 公开了在其表面的一部分上具有亲水涂层的生物医学装置，所述生物医学装置包括：（a）由单体混合物的聚合产物获得的生物医学装置，其包含（i）含有硼酸部分的可聚合单体和 吸电子部分; 和（ii）生物医学装置形成共聚单体; 和（b）沿着聚合物链具有互补的反应性官能团的亲水性反应性聚合物，其中沿着（b）的亲水性反应性聚合物的聚合物链的互补反应性官能团与（a）的生物医学装置的硼酸部分结合， 从而产生生物相容性涂层，其可以被去除并重新施加以将生物医学装置的表面性质恢复到基本上新的状态。 还公开了用于治疗生物医学装置的方法。

    Method of Applying Renewable Polymeric Lens Coating
    5.
    发明申请
    Method of Applying Renewable Polymeric Lens Coating 失效
    应用可再生聚合物镜片涂层的方法

    公开(公告)号：US20100168855A1

    公开(公告)日：2010-07-01

    申请号：US12641422

    申请日：2009-12-18

    申请人： Joseph A. McGee ,  David Paul Vanderbilt ,  Paul L. Valint, JR.

    发明人： Joseph A. McGee ,  David Paul Vanderbilt ,  Paul L. Valint, JR.

    IPC分类号： A61F2/02 ,  B05D7/00 ,  B65B55/02 ,  C08L33/04 ,  G02C7/04

    CPC分类号： G02B1/043 ,  A61L27/34 ,  A61L29/085 ,  A61L31/10 ,  A61L2400/18 ,  A61L2430/16

    摘要： Disclosed are biomedical devices having a hydrophilic coating on a portion of a surface thereof, the biomedical device comprising: (a) a biomedical device obtained from a polymerization product of a monomeric mixture comprising (i) a polymerizable monomer containing a boronic acid moiety and an electron withdrawing moiety; and (ii) a biomedical device-forming comonomer; and (b) a hydrophilic reactive polymer having complementary reactive functionalities along the polymer chain, wherein the complementary reactive functionalities along the polymer chain of the hydrophilic reactive polymer of (b) bind with the boronic acid moieties of the biomedical device of (a), thereby producing a biocompatible coating which can be removed and re-applied to restore the surface properties of the biomedical device to substantially as-new condition. Methods for treating the biomedical device are also disclosed.

    摘要翻译： 公开了在其表面的一部分上具有亲水涂层的生物医学装置，所述生物医学装置包括：（a）由单体混合物的聚合产物获得的生物医学装置，其包含（i）含有硼酸部分的可聚合单体和 吸电子部分; 和（ii）生物医学装置形成共聚单体; 和（b）沿着聚合物链具有互补的反应性官能团的亲水性反应性聚合物，其中沿着（b）的亲水性反应性聚合物的聚合物链的互补反应性官能团与（a）的生物医学装置的硼酸部分结合， 从而产生生物相容性涂层，其可以被去除并重新施加以将生物医学装置的表面性质恢复到基本上新的状态。 还公开了用于治疗生物医学装置的方法。

    Surface Modified Biomedical Devices
    6.
    发明申请
    Surface Modified Biomedical Devices 审中-公开
    表面改性生物医学装置

    公开(公告)号：US20100168851A1

    公开(公告)日：2010-07-01

    申请号：US12641412

    申请日：2009-12-18

    申请人： David Paul Vanderbilt ,  Paul L. Valint, JR. ,  Joseph A. McGee

    发明人： David Paul Vanderbilt ,  Paul L. Valint, JR. ,  Joseph A. McGee

    IPC分类号： A61F2/16 ,  B05D7/00 ,  B65B55/02 ,  G02C7/04

    CPC分类号： G02B1/043 ,  A61F2/1613 ,  C08L63/00 ,  C08L85/04 ,  C08L33/068

    摘要： Disclosed are surface modified biomedical devices having a coating on a surface thereof, the coating comprising an inner layer comprising a polymer comprising monomeric units derived from an ethylenically unsaturated monomer containing a boronic acid moiety, and an outer layer comprising a hydrophilic hydrolyzed reactive polymer comprising monomeric units derived from an ethylenically unsaturated containing monomer having hydrolyzable reactive functionalities.

    摘要翻译： 公开了在其表面上具有涂层的表面改性的生物医学装置，该涂层包含内层，该内层包含衍生自含有硼酸部分的烯属不饱和单体的单体单元的聚合物，以及包含亲水性水解反应性聚合物的外层，其包含单体 衍生自具有可水解反应性官能团的含烯属不饱和单体的单元。

    Packaging solutions
    10.
    发明授权
    Packaging solutions 有权
    包装解决方案

    公开(公告)号：US08631631B2

    公开(公告)日：2014-01-21

    申请号：US12641434

    申请日：2009-12-18

    申请人： David Paul Vanderbilt ,  Paul L. Valint, Jr.

    发明人： David Paul Vanderbilt ,  Paul L. Valint, Jr.

    IPC分类号： B65B25/00 ,  B65B55/02

    CPC分类号： C08F290/04 ,  B65B25/008 ,  C08F290/046 ,  C11D3/0078 ,  C11D3/3765 ,  C11D3/3773 ,  C11D3/3776 ,  C08F230/06

    摘要： Packaging systems for storing ophthalmic devices such as contact lenses and to methods for packaging such ophthalmic devices with solutions to improve the comfort of the lenses during wear are disclosed. A packaging system includes an ophthalmic device stored in an aqueous packaging solution comprising a brush copolymer comprising (a) monomeric units derived from an ethylenically unsaturated monomer containing one or more boronic acid moieties; and (b) monomeric units derived from an ethylenically unsaturated-containing hydrophilic macromonomer.

    摘要翻译： 公开了用于存储诸如隐形眼镜的眼科装置的包装系统，以及用于包装这些眼科装置的方法以提供穿戴期间镜片的舒适度的解决方案。 包装系统包括存储在含水包装溶液中的眼科装置，其包含刷共聚物，其包含（a）衍生自含有一个或多个硼酸部分的烯属不饱和单体的单体单元; 和（b）衍生自含烯键式不饱和的亲水性大分子单体的单体单元。