摘要:
The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
摘要:
Embodiments of the present invention provide the use of average CT (ACT) to match the temporal resolution of CT and PET to enhance PET imaging and evaluated tumor quantification with HCT and ACT. For example, an embodiment of a method of enhanced PET imaging on a PET/CT scanner includes generating an average CT scan responsive to 4D CT emission image data to thereby correct attenuation in PET emission image data. Another embodiment of a method of attenuation correction in a PET/CT scan includes averaging a plurality of consecutive low dose CT images of approximately one breathing cycle to thereby obtain an average CT.
摘要翻译:本发明的实施例提供使用平均CT(ACT)来匹配CT和PET的时间分辨率以增强PET成像并用HCT和ACT评价肿瘤定量。 例如,在PET / CT扫描仪上增强PET成像的方法的实施例包括响应于4DCT发射图像数据产生平均CT扫描,从而校正PET发射图像数据中的衰减。 PET / CT扫描中的衰减校正方法的另一实施例包括对大约一个呼吸周期的多个连续的低剂量CT图像进行平均,从而获得平均CT。
摘要:
The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
摘要:
The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
摘要:
The present invention relates to substituted piperazine compounds that are useful modulators of muscarinic receptors. The present invention also provides compositions comprising such compounds, and methods for treating muscarinic receptor mediated diseases.
摘要:
The present invention relates to substituted piperazine compounds that are useful modulators of muscarinic receptors. The present invention also provides compositions comprising such compounds, and methods for treating muscarinic receptor mediated diseases.
摘要:
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要:
The present invention relates to compounds useful as modulators of the vanilloid receptor, and also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要:
A system for constructing golf course traps which would include the steps of forming a cutout area in the fairway in the desired shape of the trap, the cutout area including a continuous substantially vertical sidewall and a substantially flat floor portion; and forming a plurality of channels for housing the "turf drain" composite drainage line within the channels for undertaking drainage of the traps; prior to the placement of the turf drain lines within the channels, placing a continuous sheet of material such as plastic liner along the floor of the trap and the continuous sheet forming within the plurality of channels; positioning the "turf drain" composite drainage line within the channels so that the plastic liner is positioned between the soil and the turf drainage line; and filling the trap with sufficient sand for allowing the upper most portion space of the sand within the trap to be substantially flush with the surrounding fairway, so that as water drains into the trap, the water would essentially follow the vertical wall of the trap, and would drain along the plastic liner layer, and to the turf drain lines to be drained from the trap, without the water ever making contact with the soil beneath the plastic liner layer or turf drain line.
摘要:
A land drainage apparatus, system, and method utilize a vacuum pump and atmospheric pressure to lift water from a collection basin to a level above a fluid intake level. After a certain amount of water is lifted and collected in a second chamber above the level of the collection basin, the vacuum can be broken, enabling the water to flow out of the second chamber by gravity flow to an exit, wherein the exit is above the fluid level intake and below the second chamber.