摘要:
This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Het and R5-R13 are set in the specification. The invention also is directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
摘要:
This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Het and R5-R13 are set in the specification. The invention also is directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
摘要:
This invention relates aryl substituted pyridines, pyrimidines, pyrazines and triazines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein A1, A2, A3, R1—R4, X and Y are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
摘要:
There is provided a method implemented in a base station (11) of providing control information to a UE (13) over a wireless communications system (10). This method includes: scrambling (32) an E-PDCCH including the control information; modulating the E-PDCCH; mapping (34) the E-PDCCH on an allocated PRB; and transmitting (12) the E-PDCCH to the UE (13). The UE (13) communicates over the wireless communications system (10) according to the control information.
摘要:
The present invention relates generally to methods for generating a dynamic pilot symbol structure in spread spectrum communication systems, and in particular to the use of pilot symbols by user equipment in channel estimation. In one form, the method includes, allocating basic pilot symbols (402) at the beginning of each data chunk (404, 406) and spread over the plurality of sub-carrier frequencies; and selectively replacing data symbols (408) in each data chunk (400) with adaptive pilot symbols (410) according to the speed of the user equipment.
摘要:
A method of encoding a bit sequence over a Physical Downlink Control Channel (PDCCH) having Downlink Control Information (DCI) including: determining DCI bits to provide a DCI bit sequence; performing a CRC calculation on the DCI bit sequence to provide a CRC parity bit sequence; scrambling the CRC parity bit sequence to provide a scrambled CRC bit sequence; if the DCI format is LTE-A, further scrambling the DCI together with the attached scrambled CRC bit sequence to provide a LTE-A scrambled bit sequence; channel coding either the DCI attached scrambled CRC bit sequence or LTE-A scrambled bit sequence to provide a channel coded bit sequence; modulating the channel coded bit sequence to provide a modulated symbol sequence; layer mapping the modulated symbol sequence to one or more antennas associated with a transmitter to provide one or more layers having a symbol sequence; and precoding the layered symbol sequences.
摘要:
A method and system for using Threat Imaging Projection (TIP) technology, and the operator testing data that it generates, in order to certify x-ray inspection system operators and thereby assure an acceptable and uniform level of operator performance. In a preferred configuration, the operator views x-ray images of objects on a screening system equipped with TIP technology. When the operator believes that a threat item image appears on the screening system, the operator indicates such via an indicating means. The system is capable of recording, storing and transmitting individual operator performance data relating to proper detections, missed detections, and false alarms, i.e., when an operator indicates that a threat item image appears when no such image actually appears on the screening system. The system preferably contains a library of various threat item images, e.g., guns, bombs, knives, etc., which are classified according to type of threat and difficulty of detection.
摘要:
A method and system for using Threat Imaging Projection (TIP) technology, and the operator testing data that it generates, in order to certify x-ray inspection system operators and thereby assure an acceptable and uniform level of operator performance. In a preferred configuration, the operator views x-ray images of objects on a screening system equipped with TIP technology. When the operator believes that a threat item image appears on the screening system, the operator indicates such via an indicating means. The system is capable of recording, storing and transmitting individual operator performance data relating to proper detections, missed detections, and false alarms, i.e., when an operator indicates that a threat item image appears when no such image actually appears on the screening system. The system preferably contains a library of various threat item images, e.g., guns, bombs, knives, etc., which are classified according to type of threat and difficulty of detection.
摘要:
A method of decoding channelisation code set information to determine the number P of channelisation codes and the code offset O in a spread spectrum data transmission, wherein the channelisation code set information 32 includes a first group of bits encoding the number of channelisation codes and a second group of bits encoding the code offset, the method including the steps of: deriving (30-40) the number P of channelisation codes according to P = C + ⌊ m - A n ⌋ ; and deriving (42-48) the code offset O according to O = ⌊ P n ⌋ × ( m - 2 B ) + ( B + 1 ) ; where m is the maximum number of multicodes allocated from the spread spectrum data transmission, n = ⌊ m 2 ⌋ + 1 , A is the value of the first group of bits of the channelisation code set information, B is the value of the second group of bits of the channelisation code set information, and C = A + ⌊ B m - A ⌋ × ( m - 2 A ) .
摘要:
This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Het and R5-R8 are set in the specification. The invention also is directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.