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公开(公告)号：US08574895B2
公开(公告)日：2013-11-05
申请号：US10541124
申请日：2003-12-30
申请人： Dominique M. Freeman , Dirk Boecker , Robert Jones , David Cullen , Malcolm MacLeod , William Carlsen , Michael J. Owen , Christopher Dryer
发明人： Dominique M. Freeman , Dirk Boecker , Robert Jones , David Cullen , Malcolm MacLeod , William Carlsen , Michael J. Owen , Christopher Dryer
CPC分类号： A61B5/14532 , A61B5/1411 , A61B5/145 , A61B5/1455 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150274 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15123 , A61B5/1513 , A61B5/15151 , A61B5/15161 , A61B5/15176 , A61B5/157 , B01L3/5025 , B01L3/502715 , B01L2200/027 , B01L2300/0803 , B01L2300/0887 , B01L2400/0406 , G01N21/6408
摘要： A device is provided for use with a tissue penetrating system and/or a metering device for measuring analyte levels. The device comprises a cartridge and a plurality of analyte detecting members mounted on the cartridge. The cartridge may have a radial disc shape. The cartridge may also be sized to fit within the metering device. The analyte detecting members may be optical system using fluorescence lifetime to determine analyte levels. In one embodiment, the device may also include a fluid spreader positioned over at least a portion of the analyte detecting member to urge fluid toward one of the detecting members. A plurality of analyte detecting members may be used. Each analyte detecting member may be a low volume device.
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公开(公告)号：US20060204399A1
公开(公告)日：2006-09-14
申请号：US10541124
申请日：2003-12-30
申请人： Dominique Freeman , Dirk Boecker , Robert Jones , David Cullen , Malcolm McLeod , William Carlsen , Michael Owen , Christopher Dryer
发明人： Dominique Freeman , Dirk Boecker , Robert Jones , David Cullen , Malcolm McLeod , William Carlsen , Michael Owen , Christopher Dryer
CPC分类号： A61B5/14532 , A61B5/1411 , A61B5/145 , A61B5/1455 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150274 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15123 , A61B5/1513 , A61B5/15151 , A61B5/15161 , A61B5/15176 , A61B5/157 , B01L3/5025 , B01L3/502715 , B01L2200/027 , B01L2300/0803 , B01L2300/0887 , B01L2400/0406 , G01N21/6408
摘要： A device is provided for use with a tissue penetrating system and/or a metering device for measuring analyte levels. The device comprises a cartridge and a plurality of analyte detecting members mounted on the cartridge. The cartridge may have a radial disc shape. The cartridge may also be sized to fit within the metering device. The analyte detecting members may be optical system using fluorescence lifetime to determine analyte levels. In one embodiment, the device may also include a fluid spreader positioned over at least a portion of the analyte detecting member to urge fluid toward one of the detecting members. A plurality of analyte detecting members may be used. Each analyte detecting member may be a low volume device.
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公开(公告)号：US08690796B2
公开(公告)日：2014-04-08
申请号：US11536720
申请日：2006-09-29
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A tissue penetrating system has a housing member. A plurality of penetrating members are positioned in the housing member. A tissue stabilizing member is coupled to the housing. A penetrating member sensor is coupled to the plurality of penetrating members. The penetrating member sensor is configured to provide information relative to a depth of penetration of a penetrating member through a skin surface.
摘要翻译： 组织穿透系统具有壳体构件。 多个穿透构件定位在壳体构件中。 组织稳定构件联接到壳体。 穿透构件传感器联接到多个穿透构件。 穿透构件传感器被配置为提供关于穿透构件穿过皮肤表面的穿透深度的信息。
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公开(公告)号：US08337419B2
公开(公告)日：2012-12-25
申请号：US11244311
申请日：2005-10-04
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden , Barry Dean Briggs , Jon Hewitt Leonard , Ray Freeman , George Gogue
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden , Barry Dean Briggs , Jon Hewitt Leonard , Ray Freeman , George Gogue
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150061 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/15019 , A61B5/150213 , A61B5/150221 , A61B5/150358 , A61B5/150427 , A61B5/150503 , A61B5/150572 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15176 , A61B5/15178 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61B17/32093 , B01L3/5027 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A tissue penetration device and method of using same. The tissue penetration device may optionally include sampling and analyzing functions, which may be integrated. An embodiment provides control of a lancet used for sampling blood. Electric field coils or solenoids may drive the lancet using electromagnetic force. Advancement and retraction of a lancet may be controlled by a feedback loop monitoring the position and velocity of the lancet embodiments of the lancet driver can be configured to follow a predetermined tissue lancing profile. Embodiments of the invention include a lancet and method for using a lancet to maintain the patency of the wound tract once the lancet has cut into the skin.
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公开(公告)号：US08197421B2
公开(公告)日：2012-06-12
申请号：US11778235
申请日：2007-07-16
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , G01N27/28 , G06F19/00 , G06Q50/24
摘要： A body fluid sampling system for use on a tissue site includes a single drive force generator. A plurality of penetrating members are operatively coupled to the force generator. The force generator moves each of the members along a path out of a housing with a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A flexible support member couples the penetrating members to define a linear array. The support member is movable and configured to move each of the penetrating members to a launch position associated with the force generator.
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公开(公告)号：US08079960B2
公开(公告)日：2011-12-20
申请号：US11539945
申请日：2006-10-10
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150083 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/15019 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150358 , A61B5/150412 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150824 , A61B5/150832 , A61B5/15087 , A61B5/150916 , A61B5/150954 , A61B5/151 , A61B5/15111 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/15146 , A61B5/15151 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15174 , A61B5/15176 , A61B5/15184 , A61B5/15186 , A61B5/1519 , A61B5/15194 , A61B17/32093 , B01L3/5027 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A lancet driver is provided wherein the driver exerts a driving force on a lancet during a lancing cycle and is used on a tissue site. The driver of includes a drive force generator for advancing the lancet along a path into the tissue site, and a sensor configured to detect lancet position along said path during the lancing cycle.
摘要翻译： 提供了一种刺血针驱动器，其中驾驶员在穿刺周期期间在柳叶刀上施加驱动力并且在组织部位上使用。 驱动器包括驱动力发生器，用于将刺血针沿着路径推进到组织部位;以及传感器，被配置为在穿刺周期期间沿着所述路径检测刺血针位置。
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公开(公告)号：US07914465B2
公开(公告)日：2011-03-29
申请号：US11672746
申请日：2007-02-08
申请人： Dominique M. Freeman , Dirk Boecker , Don Alden
发明人： Dominique M. Freeman , Dirk Boecker , Don Alden
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A skin penetrating system has a housing member and a plurality of penetrating members positioned in the housing member. A tissue stabilizing device is coupled to the housing member. A user interface is configured to relay at least one of, skin penetrating performance or a skin penetrating setting.
摘要翻译： 皮肤穿透系统具有壳体构件和定位在壳体构件中的多个穿透构件。 组织稳定装置联接到壳体构件。 用户界面被配置为中继皮肤穿透性能或皮肤穿透设置中的至少一种。
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8.发明授权Method and apparatus for a multi-use body fluid sampling device with optical analyte sensing 有权用于具有光学分析物感测的多用途体液采样装置的方法和装置公开(公告)号：US07713214B2
公开(公告)日：2010-05-11
申请号：US10324053
申请日：2002-12-18
申请人： Dominique M. Freeman , Dirk Boecker
发明人： Dominique M. Freeman , Dirk Boecker
IPC分类号： A61B5/00
CPC分类号： A61B5/1411 , A61B5/1427 , A61B5/14532 , A61B5/14546 , A61B5/1455 , A61B5/1486 , A61B5/150022 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150221 , A61B5/150358 , A61B5/150412 , A61B5/150427 , A61B5/150503 , A61B5/150519 , A61B5/150572 , A61B5/150664 , A61B5/150824 , A61B5/15087 , A61B5/150916 , A61B5/151 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/15146 , A61B5/15151 , A61B5/15153 , A61B5/15161 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/15182 , A61B5/15184 , A61B5/15186 , A61B5/157 , A61M37/0015
摘要： A device for use with a penetrating member driver to penetrate tissue is provided. The device includes a single cartridge coupled to a plurality of penetrating members and operatively couplable to the penetrating member driver. The penetrating members are movable to extend radially outward from the cartridge to penetrate tissue. A plurality of optical analyte sensors are coupled to the single cartridge and positioned to receive body fluid from a wound in the tissue created by the penetrating member.
摘要翻译： 提供了一种用于穿透构件驱动器以穿透组织的装置。 该装置包括联接到多个穿透构件并且可操作地联接到穿透构件驱动器的单个筒。 穿透构件可移动以从筒体径向向外延伸以穿透组织。 多个光学分析物传感器耦合到单个盒并定位成从穿透构件产生的组织中的伤口接收体液。
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公开(公告)号：US07682318B2
公开(公告)日：2010-03-23
申请号：US10363508
申请日：2002-06-12
申请人： Don Alden , Dominique M. Freeman , Paul Lum , Vladimir Drbal , Catherine K. Templin , Dirk Boecker
发明人： Don Alden , Dominique M. Freeman , Paul Lum , Vladimir Drbal , Catherine K. Templin , Dirk Boecker
IPC分类号： A61B5/00
CPC分类号： A61B5/15186 , A61B5/150022 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/15019 , A61B5/150213 , A61B5/150221 , A61B5/150229 , A61B5/150412 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150916 , A61B5/15111 , A61B5/15117 , A61B5/15146 , A61B5/15151 , A61B5/15174
摘要： Blood samples can be collected without substantial contamination from ambient air, such that the blood sample may be analyzed accurately for gaseous components such as oxygen and carbon dioxide. An embodiment of the device has integrated actuation, lancing, and sample acquisition components, which in some embodiments are miniaturized and/or disposable.
摘要翻译： 可以收集血液样本而没有来自环境空气的实质污染，使得可以准确地分析血液样品用于气体组分如氧气和二氧化碳。 该装置的一个实施例具有集成的致动，采血和采样部件，其在一些实施例中是小型化和/或一次性的。
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公开(公告)号：US07648468B2
公开(公告)日：2010-01-19
申请号：US10335252
申请日：2002-12-31
申请人： Dirk Boecker , Don Alden , Dominique M. Freeman
发明人： Dirk Boecker , Don Alden , Dominique M. Freeman
IPC分类号： A61B5/00
CPC分类号： G01N33/557 , A61B5/14532 , A61B5/14546 , A61B5/150022 , A61B5/150068 , A61B5/150099 , A61B5/150152 , A61B5/150167 , A61B5/150175 , A61B5/150213 , A61B5/150251 , A61B5/150358 , A61B5/150435 , A61B5/150503 , A61B5/150572 , A61B5/150809 , A61B5/150816 , A61B5/150824 , A61B5/15087 , A61B5/15107 , A61B5/15123 , A61B5/15151 , A61B5/15153 , A61B5/15163 , A61B5/15169 , A61B5/15171 , A61B5/15178 , A61B5/157 , A61B17/32093 , A61M2005/004 , B01L3/5027 , B01L3/502715 , B01L2200/10 , B01L2300/0663 , B01L2300/18 , G01N33/4905
摘要： A body fluid sampling system for use on a tissue site includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generator moves the member along a path out of a housing having a penetrating member exit, into the tissue site, stops in the tissue site, and withdraws out of the tissue site. A cartridge houses the penetrating member. The cartridge has first and second seals coupled to the penetrating member to maintain a sterile environment around a portion of the penetration member prior to penetrating member actuation.
摘要翻译： 用于组织部位的体液取样系统包括电动驱动力发生器。 穿透构件可操作地联接到力发生器。 力产生器将构件沿着路径移动离开具有穿透构件出口的壳体，进入组织部位，在组织部位停止，并从组织部位抽出。 墨盒容纳穿透构件。 筒具有联接到穿透构件的第一和第二密封件，以在穿透构件致动之前保持穿透构件的一部分周围的无菌环境。
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