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公开(公告)号：US5612360A
公开(公告)日：1997-03-18
申请号：US49916
申请日：1993-04-20
申请人： Donald B. Boyd , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , K. Jeff Thrasher , Venkatraghavan Vasudevan , Celia A. Whitesitt
发明人： Donald B. Boyd , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , K. Jeff Thrasher , Venkatraghavan Vasudevan , Celia A. Whitesitt
IPC分类号： A61K31/40 , A61K31/401 , A61K31/403 , A61K31/404 , A61K31/415 , A61K31/4184 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K38/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P13/02 , A61P15/00 , A61P27/02 , A61P27/06 , A61P43/00 , C07D209/08 , C07D209/12 , C07D209/30 , C07D231/56 , C07D235/06 , C07D235/08 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/10 , C07D403/12 , C07D403/14 , C07D471/04 , C07D491/10 , C07F9/6524 , C07K5/06 , C07K5/078 , C07K14/81 , A61K31/41 , C07D471/00
CPC分类号： C07D403/14 , C07D209/08 , C07D401/14 , C07D403/10 , C07D403/12 , C07D471/04 , C07D491/10 , C07K5/06139 , C07K5/06191 , A61K38/00
摘要： This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.
摘要翻译： 本发明提供新的杂环衍生物，其药物制剂及其在哺乳动物中拮抗血管紧张素II受体的用途。
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公开(公告)号：US5693633A
公开(公告)日：1997-12-02
申请号：US453591
申请日：1995-05-30
申请人： Donald B. Boyd , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , K. Jeff Thrasher , Venkatraghavan Vasudevan , Celia A. Whitesitt
发明人： Donald B. Boyd , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , K. Jeff Thrasher , Venkatraghavan Vasudevan , Celia A. Whitesitt
IPC分类号： A61K31/40 , A61K31/401 , A61K31/403 , A61K31/404 , A61K31/415 , A61K31/4184 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K38/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P13/02 , A61P15/00 , A61P27/02 , A61P27/06 , A61P43/00 , C07D209/08 , C07D209/12 , C07D209/30 , C07D231/56 , C07D235/06 , C07D235/08 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/10 , C07D403/12 , C07D403/14 , C07D471/04 , C07D491/10 , C07F9/6524 , C07K5/06 , C07K5/078 , C07K14/81 , A61K31/395 , A61K31/41
CPC分类号： C07D403/14 , C07D209/08 , C07D401/14 , C07D403/10 , C07D403/12 , C07D471/04 , C07D491/10 , C07K5/06139 , C07K5/06191 , A61K38/00
摘要： This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.
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公开(公告)号：US5569768A
公开(公告)日：1996-10-29
申请号：US455239
申请日：1995-05-31
申请人： Donald B. Boyd , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , K. Jeff Thrasher , Venkatraghavan Vasudevan , Celia A. Whitesitt
发明人： Donald B. Boyd , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , K. Jeff Thrasher , Venkatraghavan Vasudevan , Celia A. Whitesitt
IPC分类号： A61K31/40 , A61K31/401 , A61K31/403 , A61K31/404 , A61K31/415 , A61K31/4184 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K38/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P13/02 , A61P15/00 , A61P27/02 , A61P27/06 , A61P43/00 , C07D209/08 , C07D209/12 , C07D209/30 , C07D231/56 , C07D235/06 , C07D235/08 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/10 , C07D403/12 , C07D403/14 , C07D471/04 , C07D491/10 , C07F9/6524 , C07K5/06 , C07K5/078 , C07K14/81 , C07D231/54 , C07D233/04 , C07D417/10 , C07D487/04
CPC分类号： C07D403/14 , C07D209/08 , C07D401/14 , C07D403/10 , C07D403/12 , C07D471/04 , C07D491/10 , C07K5/06139 , C07K5/06191 , A61K38/00
摘要： This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.
摘要翻译： 本发明提供新的杂环衍生物，其药物制剂及其在哺乳动物中拮抗血管紧张素II受体的用途。
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公开(公告)号：US5556981A
公开(公告)日：1996-09-17
申请号：US453532
申请日：1995-05-30
申请人： Donald B. Boyd , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , K. Jeff Thrasher , Venkatraghaven Vasudevan , Celia A. Whitesitt
发明人： Donald B. Boyd , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , K. Jeff Thrasher , Venkatraghaven Vasudevan , Celia A. Whitesitt
IPC分类号： A61K31/40 , A61K31/401 , A61K31/403 , A61K31/404 , A61K31/415 , A61K31/4184 , A61K31/435 , A61K31/44 , A61K31/4427 , A61K38/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P13/02 , A61P15/00 , A61P27/02 , A61P27/06 , A61P43/00 , C07D209/08 , C07D209/12 , C07D209/30 , C07D231/56 , C07D235/06 , C07D235/08 , C07D235/12 , C07D235/14 , C07D235/16 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/10 , C07D403/12 , C07D403/14 , C07D471/04 , C07D491/10 , C07F9/6524 , C07K5/06 , C07K5/078 , C07K14/81 , C07D413/10
CPC分类号： C07D403/14 , C07D209/08 , C07D401/14 , C07D403/10 , C07D403/12 , C07D471/04 , C07D491/10 , C07K5/06139 , C07K5/06191 , A61K38/00
摘要： This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.
摘要翻译： 本发明提供新的杂环衍生物，其药物制剂及其在哺乳动物中拮抗血管紧张素II受体的用途。
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公开(公告)号：US5484780A
公开(公告)日：1996-01-16
申请号：US355778
申请日：1994-12-14
申请人： Donald B. Boyd , Kenneth L. Hauser , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Kumiko Takeuchi , K. Jeff Thrasher , Celia A. Whitesitt
发明人： Donald B. Boyd , Kenneth L. Hauser , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Kumiko Takeuchi , K. Jeff Thrasher , Celia A. Whitesitt
IPC分类号： C07D233/64 , A61K31/41 , A61K31/415 , A61K31/4164 , A61K31/42 , A61K31/425 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/47 , A61K31/675 , A61P9/00 , A61P9/12 , A61P13/02 , A61P15/00 , A61P25/28 , A61P27/02 , A61P27/06 , A61P43/00 , C07D233/58 , C07D233/70 , C07D233/88 , C07D233/90 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F9/6506 , C07F9/6524 , C07F9/02 , C07D231/10
CPC分类号： C07D401/12 , C07D233/88 , C07D401/14 , C07D403/06 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their methods of use for antagonizing angiotensin II receptors in mammals.
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公开(公告)号：US5401851A
公开(公告)日：1995-03-28
申请号：US049917
申请日：1993-04-20
申请人： Donald B. Boyd , Kenneth L. Hauser , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Kumiko Takeuchi , K. Jeff Thrasher , Celia A. Whitesitt
发明人： Donald B. Boyd , Kenneth L. Hauser , Sherryl L. Lifer , Winston S. Marshall , Alan D. Palkowitz , William Pfeifer , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Kumiko Takeuchi , K. Jeff Thrasher , Celia A. Whitesitt
IPC分类号： C07D233/64 , A61K31/41 , A61K31/415 , A61K31/4164 , A61K31/42 , A61K31/425 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/47 , A61K31/675 , A61P9/00 , A61P9/12 , A61P13/02 , A61P15/00 , A61P25/28 , A61P27/02 , A61P27/06 , A61P43/00 , C07D233/58 , C07D233/70 , C07D233/88 , C07D233/90 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07F9/6506 , C07F9/6524 , A61K31/505 , C07D213/06 , C07D239/26
CPC分类号： C07D401/12 , C07D233/88 , C07D401/14 , C07D403/06 , C07D403/14 , C07D405/14 , C07D409/14 , C07D413/14
摘要： This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their methods of use for antagonizing angiotensin II receptors in mammals.
摘要翻译： 本发明提供新颖的苯基和杂环衍生物，其药物制剂及其用于拮抗哺乳动物血管紧张素II受体的方法。
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公开(公告)号：US5563278A
公开(公告)日：1996-10-08
申请号：US453537
申请日：1995-05-30
申请人： Sherryl L. Lifer , Winston S. Marshall , Fariborz Mohamadi , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Celia A. Whitesitt
发明人： Sherryl L. Lifer , Winston S. Marshall , Fariborz Mohamadi , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Celia A. Whitesitt
IPC分类号： A61K31/075 , A61K31/00 , A61K31/085 , A61K31/13 , A61K31/16 , A61K31/18 , A61K31/19 , A61K31/35 , A61K31/352 , A61K31/40 , A61K31/41 , A61K31/415 , A61P5/00 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P43/00 , C07C63/331 , C07C65/24 , C07C65/34 , C07C69/76 , C07C205/56 , C07C229/42 , C07C235/24 , C07C255/41 , C07D207/34 , C07D231/12 , C07D231/14 , C07D231/20 , C07D231/38 , C07D233/88 , C07D233/90 , C07D249/04 , C07D249/06 , C07D249/08 , C07D249/10 , C07D249/12 , C07D249/14 , C07D257/04 , C07D257/06 , C07D311/82 , C07D311/84 , C07D311/86 , C07D311/88 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , A61K31/215 , A61K31/275 , C07C69/66
CPC分类号： C07D257/04 , C07C229/42 , C07C255/41 , C07C65/24 , C07C65/34 , C07C69/76 , C07D207/34 , C07D231/14 , C07D233/88 , C07D233/90 , C07D249/10 , C07D257/06 , C07D403/04 , C07D403/12 , C07D405/12
摘要： This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their use for antagonizing angiotensin II receptors in mammals.
摘要翻译： 本发明提供新颖的苯基和杂环衍生物，它们的药物制剂及其在哺乳动物中拮抗血管紧张素II受体的用途。
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公开(公告)号：US5571925A
公开(公告)日：1996-11-05
申请号：US183685
申请日：1994-01-19
申请人： Sherryl L. Lifer , Winston S. Marshall , Fariborz Mohamadi , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Celia A. Whitesitt
发明人： Sherryl L. Lifer , Winston S. Marshall , Fariborz Mohamadi , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Celia A. Whitesitt
IPC分类号： A61K31/075 , A61K31/00 , A61K31/085 , A61K31/13 , A61K31/16 , A61K31/18 , A61K31/19 , A61K31/35 , A61K31/352 , A61K31/40 , A61K31/41 , A61K31/415 , A61P5/00 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P43/00 , C07C63/331 , C07C65/24 , C07C65/34 , C07C69/76 , C07C205/56 , C07C229/42 , C07C235/24 , C07C255/41 , C07D207/34 , C07D231/12 , C07D231/14 , C07D231/20 , C07D231/38 , C07D233/88 , C07D233/90 , C07D249/04 , C07D249/06 , C07D249/08 , C07D249/10 , C07D249/12 , C07D249/14 , C07D257/04 , C07D257/06 , C07D311/82 , C07D311/84 , C07D311/86 , C07D311/88 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D407/12
CPC分类号： C07D257/04 , C07C229/42 , C07C255/41 , C07C65/24 , C07C65/34 , C07C69/76 , C07D207/34 , C07D231/14 , C07D233/88 , C07D233/90 , C07D249/10 , C07D257/06 , C07D403/04 , C07D403/12 , C07D405/12
摘要： This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their use for antagonizing angiotensin II receptors in mammals.
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公开(公告)号：US5073566A
公开(公告)日：1991-12-17
申请号：US444456
申请日：1989-11-30
申请人： Sherryl L. Lifer , Winston S. Marshall , Fariborz Mohamadi , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Celia A. Whitesitt
发明人： Sherryl L. Lifer , Winston S. Marshall , Fariborz Mohamadi , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Celia A. Whitesitt
IPC分类号： A61K31/075 , A61K31/00 , A61K31/085 , A61K31/13 , A61K31/16 , A61K31/18 , A61K31/19 , A61K31/35 , A61K31/352 , A61K31/40 , A61K31/41 , A61K31/415 , A61P5/00 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P43/00 , C07C63/331 , C07C65/24 , C07C65/34 , C07C69/76 , C07C205/56 , C07C229/42 , C07C235/24 , C07C255/41 , C07D207/34 , C07D231/12 , C07D231/14 , C07D231/20 , C07D231/38 , C07D233/88 , C07D233/90 , C07D249/04 , C07D249/06 , C07D249/08 , C07D249/10 , C07D249/12 , C07D249/14 , C07D257/04 , C07D257/06 , C07D311/82 , C07D311/84 , C07D311/86 , C07D311/88 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12
CPC分类号： C07D257/04 , C07C229/42 , C07C255/41 , C07C65/24 , C07C65/34 , C07C69/76 , C07D207/34 , C07D231/14 , C07D233/88 , C07D233/90 , C07D249/10 , C07D257/06 , C07D403/04 , C07D403/12 , C07D405/12
摘要： This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their use for antagonizing angiotensin II receptors in mammals.
摘要翻译： 本发明提供新颖的苯基和杂环衍生物，它们的药物制剂及其在哺乳动物中拮抗血管紧张素II受体的用途。
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公开(公告)号：US5312936A
公开(公告)日：1994-05-17
申请号：US761127
申请日：1991-09-17
申请人： Sherryl L. Lifer , Winston S. Marshall , Fariborz Mohamadi , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Celia A. Whitesitt
发明人： Sherryl L. Lifer , Winston S. Marshall , Fariborz Mohamadi , Jon K. Reel , Richard L. Simon , Mitchell I. Steinberg , Celia A. Whitesitt
IPC分类号： A61K31/075 , A61K31/00 , A61K31/085 , A61K31/13 , A61K31/16 , A61K31/18 , A61K31/19 , A61K31/35 , A61K31/352 , A61K31/40 , A61K31/41 , A61K31/415 , A61P5/00 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P43/00 , C07C63/331 , C07C65/24 , C07C65/34 , C07C69/76 , C07C205/56 , C07C229/42 , C07C235/24 , C07C255/41 , C07D207/34 , C07D231/12 , C07D231/14 , C07D231/20 , C07D231/38 , C07D233/88 , C07D233/90 , C07D249/04 , C07D249/06 , C07D249/08 , C07D249/10 , C07D249/12 , C07D249/14 , C07D257/04 , C07D257/06 , C07D311/82 , C07D311/84 , C07D311/86 , C07D311/88 , C07D403/04 , C07D403/06 , C07D403/12 , C07D405/06 , C07D405/12 , C07D233/44
CPC分类号： C07D257/04 , C07C229/42 , C07C255/41 , C07C65/24 , C07C65/34 , C07C69/76 , C07D207/34 , C07D231/14 , C07D233/88 , C07D233/90 , C07D249/10 , C07D257/06 , C07D403/04 , C07D403/12 , C07D405/12
摘要： This invention provides novel phenyl and heterocyclic derivatives, their pharmaceutical formulations and their use for antagonizing angiotensin II receptors in mammals.
摘要翻译： 本发明提供新颖的苯基和杂环衍生物，它们的药物制剂及其在哺乳动物中拮抗血管紧张素II受体的用途。
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