摘要:
A process for preparing a compound of the formula I: or pharmaceutical acceptable salts thereof wherein X is —NR1—, —S(O)g—, or —O—; R1 is —H, C1-6 alkyl optionally substituted with one or more —OH, —CN, or halo, or R1 is —(CH2)h-aryl, —COR1-1, —COOR1-2, —CO—(CH2)h—COR1-1, C1-6 alkyl sulfonyl, —SO2—(CH2)h-aryl, or —(CO)i-Het; R2 is —H, C1-6 alkyl, —(CH2)h-aryl, or halo; R3 and R4 are the same or different and are —H or halo; R5 is —H, C1-12 alkyl optionally substituted with one or more halo, C3-12 cycloalkyl, C1-6 alkoxy. The compounds are useful antimicrobial agents.
摘要:
The instant-mount aspect of the present invention allows a user to rapidly accurately dismount a mounted CNC calibration device from a CNC work table, and rapidly replace the CNC calibration device to its previously mounted position within 0.0001, in seconds. The alignment aspect of the present invention allows faster and more robust high-accuracy alignment of a CNC calibration device once it is mounted on a CNC work table. The remote nest aspect of the present invention allows rapid re-positioning of a CNC calibration device within a CNC milling machine cabinet in a way that does not disrupt the data connection between the CNC control computer and the CNC calibration device, and allows for utilization of more of the worktable surface during milling operations.
摘要:
A power pin alignment and crimping fixture having a fixture body. The fixture body includes a plurality of channels each having a first open end and a second open end. The plurality of channels are disposed at an angle diverging away from one another in a direction from the first open end to the second open end such that each of the plurality of channels are disposed along a corresponding side edge of a symmetrical shape.
摘要:
A hitch receiver stand comprises a hitch receiver assembly having a hitch receiver than can removably mount a device having a standard hitch and is removably attached to a framework. The framework may include a number of releasably coupled components.
摘要:
A system and method that includes, in an embodiment, a prism, a camera, a light source, and a plate. The system, in an embodiment, is configured for scanning a roll and generating an image of the roll surface. The prism, in an embodiment, is positioned below the camera and above the plate. In an embodiment, the plate is positioned below the prism and above the roll surface. In an embodiment, the light source is positioned above the prism. In an embodiment, the light source and the prism are positioned to provide light to the roll surface at an angle of at least 75 degrees measured from a line normal to the roll surface. In an embodiment, the prism is configured to refract light from the light source, the camera is a line scan camera that includes a row of pixel sensors, and the light source includes light emitting diodes.
摘要:
An apparatus comprises a flexible substrate. The flexible substrate includes a first substrate surface, a surface electrode array that includes a plurality of electrodes disposed on the first substrate surface, one or more flexible neural probes substantially orthogonal to the first substrate surface and insertable into biological tissue, and a penetrating electrode array that includes a plurality of electrodes formed on the one or more flexible neural probes, wherein electrodes of the surface electrode array and the penetrating electrode array are configured to one or both of receive a neural signal from a neural signal source and provide electrical stimulation energy to a neural stimulation target.
摘要:
Techniques suitable for identifying potential subjects for a clinical trial and other applications are disclosed. One or more exclusion or inclusion criteria are defined for the clinical trial. One or more specialized searching tables are pre-generated using administrative healthcare claims data and the one or more exclusion or inclusion criteria. The specialized searching tables are searched. Through the searching step, subjects are identified within the administrative healthcare claims data who match the one or more exclusion or inclusion criteria. Through the searching step, a geographical area is identified corresponding to the subjects who match the one or more exclusion or inclusion criteria. A customized report is generated using the identified subjects and geographical area.
摘要:
Camera arrangements that can include electromagnetic protection, such as from EMP/IEMI events, is disclosed. One example camera arrangement includes a camera including a viewfinder having a lens, and an electromagnetically shielded enclosure defining an interior volume containing the camera and configured to include at least one opening aligned with the lens. The camera arrangement includes a waveguide beyond cutoff disposed across the at least one opening, the waveguide beyond cutoff including a plurality of cells sized and oriented to shield the interior volume of the enclosure from electromagnetic signals while exposing an optical path between the lens and objects external to the enclosure.
摘要:
An apparatus comprises a flexible substrate including a modular electrode array disposed on the flexible substrate. The modular electrode array includes a plurality of electrode modules, where an electrode module includes a plurality of electrodes. The flexible substrate also includes a spatial separation between the electrode modules of the modular electrode array, and conductive interconnect coupled to the electrodes of the plurality of electrodes.
摘要:
A method and system enables sharing content between a plurality of users over a communications network. A link to content that has been shared by a user is selected, the link includes at least one access characteristic defining a set of users able to access the content. A request signal including the at least one access characteristic associated with the content and at least one user characteristic associated with a requesting user over the communications network is transmitted for receipt by an authorization processor. A level of access available is determined for the content by comparing the at least one access characteristic and the at least one user characteristic in the request signal with a source of content specific authentication information including data representing content-specific access levels. Access to the requested content is provided via an internet interface to an output device in accordance with the determined level of access.