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公开(公告)号：US11571216B2
公开(公告)日：2023-02-07
申请号：US16886720
申请日：2020-05-28
发明人： Mark M. Dehdashtian , Teodoro S. Jimenez , Nathan Satter , Fabian Daniel Schroeder , Raffaele Mazzei , Jeff Kosmoski , Shahram Zamani , Adam J. Yestrepsky
摘要： Aortic occlusion and embolic protection devices include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.
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公开(公告)号：US20230277305A1
公开(公告)日：2023-09-07
申请号：US18314752
申请日：2023-05-09
IPC分类号： A61F2/24
CPC分类号： A61F2/2409 , A61F2230/0006 , A61F2230/0008 , A61F2230/0034 , A61F2250/0098
摘要： Docking stations are configured to retain and position a transcatheter heart valve in a circulatory system. The docking stations can comprise an expandable frame. The docking stations can include an enlarged first end portion having a first outer radial portion with a first major lateral dimension, an enlarged second end portion having a second outer radial portion with a second major lateral dimension, and a narrowed central waist portion having an inner radial portion with a third major lateral dimension smaller than the first and second major lateral dimensions. A retaining portion is at least partially defined by at least one of the first and second end portions, and a valve seat is at least partially defined by the waist portion. The docking station can be configured to adapt a native tricuspid valve to accept a smaller transcatheter heart valve.
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公开(公告)号：US20240033079A1
公开(公告)日：2024-02-01
申请号：US18482636
申请日：2023-10-06
发明人： Shahram Zamani , Waina Michelle Chu , Ziv Yohanan , Dikla Kersh
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2250/0018 , A61F2250/0037 , A61F2250/0036 , A61F2240/001
摘要： Disclosed herein are implantable medical devices comprising a textile material comprising a first material and a second material having different stretchability and flexibility, where the first and the second materials are at least partially superposed and coupled to each other. The medical devices of the current disclosure can be implantable prosthetic valves. The valves of the present disclosure provide for a reduced crimped profile and improve PVL sealing. In addition, disclosed herein are methods of making the implantable medical devices.
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公开(公告)号：US11654023B2
公开(公告)日：2023-05-23
申请号：US16521226
申请日：2019-07-24
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2412 , A61F2/2418 , A61F2/2436 , A61F2/2439 , A61F2/2463 , A61F2220/0075 , A61F2250/0028 , A61F2250/0069
摘要： A prosthetic heart valve includes a frame that is radially collapsible and expandable between a collapsed configuration and an expanded configuration, and defines a longitudinal axis. A leaflet structure situated within the frame, and a sealing member is disposed around the frame. The sealing member can include a first portion extending circumferentially around a portion of the frame, the first portion being configured to resiliently stretch in a direction along the longitudinal axis between a first state corresponding to the expanded configuration of the frame and a second state corresponding to the collapsed configuration of the frame. The sealing member can include a second portion extending circumferentially around a portion of the frame, the second portion being configured to resiliently stretch in a circumferential direction between a first state corresponding to the collapsed configuration of the frame and a second state corresponding to the expanded configuration of the frame.
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公开(公告)号：US20230017301A1
公开(公告)日：2023-01-19
申请号：US17935891
申请日：2022-09-27
发明人： Elena Sherman , Michael Bukin , Sandip Vasant Pawar , Shahram Zamani , Tamir S. Levi , Noam Nir , Yana Mayatskaya , Alexander Barash , Ziv Yohanan , Nikolay Gurovich , Itai Pelled
IPC分类号： A61F2/24
摘要： An implantable prosthetic device can include a frame movable between a radially compressed and a radially expanded configuration and a sealing member. The frame can include an inflow end portion, an outflow end portion, and a plurality of struts. The sealing member can be disposed around the frame and can include a cushioning layer comprising a plurality of texturized yarns extending along the longitudinal axis of the frame, and a base layer disposed between the cushioning layer and the frame.
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公开(公告)号：US20230011247A1
公开(公告)日：2023-01-12
申请号：US17933436
申请日：2022-09-19
发明人： Shahram Zamani , Robert James Gerard , Alison Louise Rodriguez , Anthony Michael Romero , John J. Desrosiers , Izaak Rosen , Andrew Paul Schaffer , Avina Gupta , Tyler Dale O'Dell , Yara Baker , Uyen Duong
IPC分类号： A61F2/24
摘要： Expandable docking stations for docking an expandable valve can include a valve seat, one or more sealing portions, and/or one or more retaining portions. The valve seat can include radiopaque markers affixed to a frame or an impermeable member. The radiopaque markers can indicate a deployment location of the valve. The docking stations can be deployed from a catheter including one or more radiopaque markers. Relative positioning of two or more radiopaque markers can provide an indication of the amount of deployment of the docking station.
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公开(公告)号：US20200289123A1
公开(公告)日：2020-09-17
申请号：US16886720
申请日：2020-05-28
发明人： Mark M. Dehdashtian , Teodoro S. Jimenez , Nathan Satter , Fabian Daniel Schroeder , Raffaele Mazzei , Jeff Kosmoski , Shahram Zamani , Adam J. Yestrepsky
摘要： Aortic occlusion and embolic protection devices include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.
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公开(公告)号：US20230270541A1
公开(公告)日：2023-08-31
申请号：US18195288
申请日：2023-05-09
发明人： Tamir S. Levi , Shahram Zamani , Michael Bukin , Ziv Yohanan , Noam Nir , Tyler Dale O'Dell , Elena Sherman
IPC分类号： A61F2/24
CPC分类号： A61F2/2415 , A61F2/2418 , A61F2220/0075
摘要： A method of assembling a valvular structure can include folding an upper tab of a first leaflet onto a lower tab of the first leaflet, disposing a first end of a reinforcing member on the upper tab, disposing a commissure member adjacent the lower tab, and coupling the first end of the reinforcing member, the tabs of the first leaflet, and the commissure member to one another. The method can further include folding an upper tab of a second leaflet onto a lower tab of the second leaflet, disposing the second leaflet adjacent the first leaflet such that the commissure member is positioned between the lower tabs, disposing a second end of the reinforcing member on the upper tab of the second leaflet, and coupling the reinforcing member, the upper and lower tabs of the second leaflet, and the commissure member to one another to form a commissure.
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公开(公告)号：US20230255762A1
公开(公告)日：2023-08-17
申请号：US18306740
申请日：2023-04-25
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2412 , A61F2/2418 , A61F2220/0075 , A61F2/2463 , A61F2/2436 , A61F2/2439 , A61F2250/0069 , A61F2250/0028
摘要： A sealing member for a prosthetic heart valve includes an annular fabric body having a first circumferential portion and a second circumferential portion. The first circumferential portion extends circumferentially around the annular fabric body and is resiliently stretchable in a direction along the longitudinal axis of the annular fabric body between an expanded configuration of the prosthetic heart valve and a collapsed configuration of the prosthetic heart valve. The second circumferential portion extends around the annular fabric body and is circumferentially offset from the first circumferential portion, the second circumferential portion being resiliently stretchable in a circumferential direction between the collapsed configuration of the prosthetic heart valve and the expanded configuration of the prosthetic heart valve.
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公开(公告)号：US20230065795A1
公开(公告)日：2023-03-02
申请号：US18054305
申请日：2022-11-10
发明人： Shahram Zamani , Tyler Dale O'Dell , Tamir S. Levi , Michael Bukin , Noam Nir , Ziv Yohanan
IPC分类号： A61F2/24
摘要： A prosthetic heart valve and associated methods for assembling a prosthetic heart valve including an annular frame and a plurality of leaflets is disclosed. As one example, the valve includes a plurality of commissures, each commissure including an attachment member including a protruding portion, a first commissure tab of a first leaflet of the plurality of leaflets arranged adjacent to a first side of the protruding portion and secured directly to the attachment member. Each commissure further includes a second commissure tab of a second leaflet of the plurality of leaflets arranged adjacent to an opposite, second side of the protruding portion and secured directly to the attachment member.
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