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    ABRASION RESISTANT FILM FOR BIOCONTAINERS
    1.
    发明申请
    ABRASION RESISTANT FILM FOR BIOCONTAINERS 审中-公开

    公开(公告)号：US20190210321A1

    公开(公告)日：2019-07-11

    申请号：US16352966

    申请日：2019-03-14

    Applicant: EMD Millipore Corporation

    Inventor： David DeCoste ,  Joseph Cianciolo ,  Michael Furbush ,  John Saragosa

    IPC: B32B5/02 ,  B32B27/08 ,  B32B27/12 ,  B32B27/32 ,  B01L3/00 ,  B32B27/40 ,  B65D75/58 ,  B65D65/40 ,  G01M3/32 ,  B32B27/34

    Abstract: A biocontainer film enhanced with an abrasion resistant or “cut-proof” substrate. Such substrates can be combined with current biocontainer materials, via various techniques of embedding, coextrusion or laminating, to maintain the cleanliness and low extractables already validated for biotech manufacturing. The substrate of choice may be constructed from materials known to be more resistant to abrasion and sharp razor type cuts or from materials oriented in such a way to prevent puncture to occur. The new substrate must also be flexible to allow for typical folding as demonstrated by current packaging practices. The new substrate may be constructed from materials other than polymers such as metal, glass or carbon or in combination with polymers. A non-constrained pressure test is also disclosed.

    Abrasion resistant film for biocontainers
    3.
    发明授权
    Abrasion resistant film for biocontainers 有权

    公开(公告)号：US10675836B2

    公开(公告)日：2020-06-09

    申请号：US16352966

    申请日：2019-03-14

    Applicant: EMD Millipore Corporation

    Inventor： David DeCoste ,  Joseph Cianciolo ,  Michael Furbush ,  John Saragosa

    IPC: B32B5/02 ,  B32B27/08 ,  B32B27/12 ,  B32B27/32 ,  B32B27/34 ,  B32B27/40 ,  B01L3/00 ,  B65D65/40 ,  B65D75/58 ,  G01M3/32

    Abstract: A biocontainer film enhanced with an abrasion resistant or “cut-proof” substrate. Such substrates can be combined with current biocontainer materials, via various techniques of embedding, coextrusion or laminating, to maintain the cleanliness and low extractables already validated for biotech manufacturing. The substrate of choice may be constructed from materials known to be more resistant to abrasion and sharp razor type cuts or from materials oriented in such a way to prevent puncture to occur. The new substrate must also be flexible to allow for typical folding as demonstrated by current packaging practices. The new substrate may be constructed from materials other than polymers such as metal, glass or carbon or in combination with polymers. A non-constrained pressure test is also disclosed.

    Interface And Fluid-Transfer System
    5.
    发明申请
    Interface And Fluid-Transfer System 有权
    接口和流体转移系统

    公开(公告)号：US20150276069A1

    公开(公告)日：2015-10-01

    申请号：US14646438

    申请日：2013-12-16

    Applicant: EMD MILLIPORE CORPORATION

    Inventor： John Saragosa ,  John Cieciuch ,  James E. Kelly ,  Luc Messier ,  Nicholas Vigorito

    IPC: F16K3/04

    CPC classification number: F16K3/04 ,  G01N1/10 ,  G01N1/22 ,  G01N1/2226 ,  G01N2001/1037

    Abstract: A fluid transfer system (100) includes a transfer device (104) and an interface device (102). The transfer device (104) includes a fluid transfer member (164) and a transfer coupling member (125) to align the fluid transfer member (164) with the interface device (102). The interface device (102) includes a reservoir port (108), a fluid transfer member receptacle (144), an interface coupling member (124), and a reservoir valve (110). The interface coupling member (124) is configured to close the fluid transfer member receptacle (144) and to couple to the transfer coupling member (125) and open the fluid transfer member receptacle (144) to receive the fluid transfer member (164). The reservoir valve (110), e.g., a sliding seal, is configured to close the reservoir port (108) from the fluid transfer member receptacle (144) and to open the reservoir port (108) to the fluid transfer member (164) when the fluid transfer member (164) is positioned in the fluid transfer member receptacle (144). The fluid transfer member (164) can include a plunger assembly configured to open and close the reservoir port (108).

    Abstract translation: 流体传输系统（100）包括传送装置（104）和接口装置（102）。 传送装置（104）包括流体传送构件（164）和传送联接构件（125），以使流体传送构件（164）与界面装置（102）对准。 接口装置（102）包括储存器端口（108），流体转移构件容器（144），界面连接构件（124）和储存器阀（110）。 接口联接构件（124）构造成关闭流体转移构件容器（144）并且联接到传递联接构件（125）并打开流体转移构件容器（144）以接收流体传递构件（164）。 储存器阀（110）（例如滑动密封件）构造成从流体转移构件接收器（144）关闭储存器端口（108）并且将储存器端口（108）打开到流体转移构件（164）时，当 流体传递构件（164）位于流体转移构件容器（144）中。 流体转移构件（164）可以包括构造成打开和关闭储存器端口（108）的柱塞组件。

    Abrasion resistant film for biocontainers
    6.
    发明授权
    Abrasion resistant film for biocontainers 有权

    公开(公告)号：US11110684B2

    公开(公告)日：2021-09-07

    申请号：US16867288

    申请日：2020-05-05

    Applicant: EMD Millipore Corporation

    Inventor： David DeCoste ,  Joseph Cianciolo ,  Michael Furbush ,  John Saragosa

    IPC: B32B5/02 ,  B32B27/08 ,  B32B27/12 ,  B32B27/32 ,  B32B27/34 ,  B32B27/40 ,  B01L3/00 ,  B65D65/40 ,  B65D75/58 ,  G01M3/32

    Abstract: A multilayered film for biocontainers, an abrasion-resistant substrate attached to the interior or the exterior side of the film wherein the substrate is one of a polymeric woven fibrous material or a polymeric non-woven fibrous material, a woven fibrous material or a non-woven fibrous material having metal fibers, a woven fibrous material or a non-woven fibrous material having glass fibers, or a woven fibrous material or a non-woven fibrous material having carbon fibers; a polymer backing to attach the substrate to the film, including one of polyolefins, polyurethanes and nylons; an outer protective layer disposed on the outside of the substrate to encapsulate the substrate; and a gas impermeable layer that includes ethylene vinyl alcohol disposed intermediate to the substrate and the outer protective layer.

    ABRASION RESISTANT FILM FOR BIOCONTAINERS
    7.
    发明申请
    ABRASION RESISTANT FILM FOR BIOCONTAINERS 审中-公开

    公开(公告)号：US20200262175A1

    公开(公告)日：2020-08-20

    申请号：US16867288

    申请日：2020-05-05

    Applicant: EMD Millipore Corporation

    Inventor： David DeCoste ,  Joseph Cianciolo ,  Michael Furbush ,  John Saragosa

    IPC: B32B5/02 ,  G01M3/32 ,  B65D75/58 ,  B65D65/40 ,  B01L3/00 ,  B32B27/40 ,  B32B27/34 ,  B32B27/32 ,  B32B27/12 ,  B32B27/08

    Abstract: A material for biocontainers including a multilayered film, the multilayered film having an interior and exterior side, an abrasion-resistant substrate attached to the interior or the exterior side of the film wherein the substrate comprises a polymeric woven fibrous material or a polymeric non-woven fibrous material, a woven fibrous material or a non-woven fibrous material comprising metal fibers, a woven fibrous material or a non-woven fibrous material comprising glass fibers, or a woven fibrous material or a non-woven fibrous material comprising carbon fibers; a polymer backing to attach the substrate to the film, the polymer backing comprising one of polyolefins, polyurethanes and nylons; an outer protective layer disposed on the outside of the substrate to encapsulate the substrate; and a gas impermeable layer that includes ethylene vinyl alcohol disposed intermediate to the substrate and the outer protective layer.

    Interface and fluid-transfer system
    8.
    发明授权
    Interface and fluid-transfer system 有权

    公开(公告)号：US09920841B2

    公开(公告)日：2018-03-20

    申请号：US14646438

    申请日：2013-12-16

    Applicant: EMD Millipore Corporation

    Inventor： John Saragosa ,  John Cieciuch ,  James E. Kelly ,  Luc Messier ,  Nicholas Vigorito

    IPC: G01N1/20 ,  F16K3/04 ,  G01N1/10 ,  G01N1/22

    CPC classification number: F16K3/04 ,  G01N1/10 ,  G01N1/22 ,  G01N1/2226 ,  G01N2001/1037

    Abstract: A fluid transfer system (100) includes a transfer device (104) and an interface device (102). The transfer device (104) includes a fluid transfer member (164) and a transfer coupling member (125) to align the fluid transfer member (164) with the interface device (102). The interface device (102) includes a reservoir port (108), a fluid transfer member receptacle (144), an interface coupling member (124), and a reservoir valve (110). The interface coupling member (124) is configured to close the fluid transfer member receptacle (144) and to couple to the transfer coupling member (125) and open the fluid transfer member receptacle (144) to receive the fluid transfer member (164). The reservoir valve (110), e.g., a sliding seal, is configured to close the reservoir port (108) from the fluid transfer member receptacle (144) and to open the reservoir port (108) to the fluid transfer member (164) when the fluid transfer member (164) is positioned in the fluid transfer member receptacle (144). The fluid transfer member (164) can include a plunger assembly configured to open and close the reservoir port (108).

    Abrasion resistant film for biocontainers
    10.
    发明授权
    Abrasion resistant film for biocontainers 有权

    公开(公告)号：US10272639B2

    公开(公告)日：2019-04-30

    申请号：US15544644

    申请日：2016-03-22

    Applicant: EMD Millipore Corporation

    Inventor： David DeCoste ,  Joseph Cianciolo ,  Michael Furbush ,  John Saragosa

    IPC: B32B5/02 ,  B32B27/08 ,  B32B27/12 ,  B32B27/32 ,  B32B27/34 ,  B32B27/40 ,  B01L3/00 ,  B65D65/40 ,  B65D75/58 ,  G01M3/32

    Abstract: A biocontainer film enhanced with an abrasion resistant or “cut-proof” substrate. Such substrates can be combined with current biocontainer materials, via various techniques of embedding, coextrusion or laminating, to maintain the cleanliness and low extractables already validated for biotech manufacturing. The substrate of choice may be constructed from materials known to be more resistant to abrasion and sharp razor type cuts or from materials oriented in such a way to prevent puncture to occur. The new substrate must also be flexible to allow for typical folding as demonstrated by current packaging practices. The new substrate may be constructed from materials other than polymers such as metal, glass or carbon or in combination with polymers. A non-constrained pressure test is also disclosed.

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