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公开(公告)号：US20150225750A1
公开(公告)日：2015-08-13
申请号：US14422180
申请日：2013-08-14
发明人： Yi-Xin Huo , Kwang Myung Cho
CPC分类号： C12P7/16 , C12M21/12 , C12M21/18 , C12M23/58 , C12P7/56 , C12P13/06 , C12P13/08 , C12P39/00 , C12Y101/01001 , C12Y104/01009 , Y02E50/10
摘要： Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.
摘要翻译： 描述了用于生产醇的方法和系统。 利用两阶段方法，其中第一阶段的发酵从含碳原料产生中间产物，例如氨基酸或有机酸。 第二阶段通过该中间产物的发酵产生醇。
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公开(公告)号：US10385366B2
公开(公告)日：2019-08-20
申请号：US16157299
申请日：2018-10-11
摘要： Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.
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公开(公告)号：US10106825B1
公开(公告)日：2018-10-23
申请号：US15336744
申请日：2016-10-27
摘要： Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.
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公开(公告)号：US10676762B2
公开(公告)日：2020-06-09
申请号：US16264009
申请日：2019-01-31
发明人： Yi-Xin Huo , Kwang Myung Cho
IPC分类号： C12N1/00 , C12N1/10 , C12P7/64 , C12P7/16 , C12P39/00 , C12M1/40 , C12M1/00 , C12P13/06 , C12P7/56 , C12P13/08
摘要： Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.
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公开(公告)号：US20190040421A1
公开(公告)日：2019-02-07
申请号：US16157299
申请日：2018-10-11
摘要： Systems, methods, and metabolically engineered microorganisms are contemplated in which low molecular weight gases, and especially methane and syngas are used as a carbon source, and in which CO2 or formaldehyde and reduction equivalents are generated for use in in vivo production of the value products.
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公开(公告)号：US10113160B2
公开(公告)日：2018-10-30
申请号：US15115670
申请日：2015-01-30
摘要： Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
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公开(公告)号：US20180216096A1
公开(公告)日：2018-08-02
申请号：US15938380
申请日：2018-03-28
CPC分类号： C12N9/88 , C10L1/00 , C10L2200/0469 , C10L2290/26 , C12N1/20 , C12N9/1205 , C12N15/74 , C12P5/026 , C12P7/16 , C12P7/625 , C12Y207/01019 , C12Y401/02009 , Y02E50/10
摘要： Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
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公开(公告)号：US20160348086A1
公开(公告)日：2016-12-01
申请号：US15115670
申请日：2015-01-30
CPC分类号： C12N9/88 , C10L1/00 , C10L2200/0469 , C10L2290/26 , C12N9/1205 , C12N15/74 , C12P5/026 , C12P7/16 , C12P7/625 , C12Y207/01019 , C12Y401/02009 , Y02E50/10
摘要： Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
摘要翻译： 提出了基因工程细胞和方法，允许从二氧化碳生产各种价值产品。 考虑的细胞具有遗传修饰的CBB循环，使得在CBB循环中固定的两个分子的CO 2可以作为单一的C2化合物从经修饰的CBB循环中排出。 在预期的方面，CBB循环包括从CBB循环的化合物产生单一C2化合物的酶活性，而对CBB循环的进一步修饰将不会在CBB循环中已经存在的催化活性之外引入另外的重组酶活性/活性 。
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公开(公告)号：US10385328B2
公开(公告)日：2019-08-20
申请号：US15938380
申请日：2018-03-28
摘要： Genetically engineered cells and methods are presented that allow for the production of various value products from CO2. Contemplated cells have a CBB cycle that is genetically modified such that two molecules of CO2 fixed in the CBB cycle can be withdrawn from the modified CBB cycle as a single C2 compound. In contemplated aspects a CBB cycle includes an enzymatic activity that generates the single C2 compound from a compound of the CBB cycle, while further modifications to the CBB cycle will not introduce additional recombinant enzymatic activity/activities outside the already existing catalytic activities in the CBB cycle.
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公开(公告)号：US10233467B2
公开(公告)日：2019-03-19
申请号：US14422180
申请日：2013-08-14
发明人： Yi-Xin Huo , Kwang Myung Cho
IPC分类号： C12P7/64 , C12P7/16 , C12P7/56 , C12N1/00 , C12N9/10 , C12M1/40 , C12M1/00 , C12P39/00 , C12P13/08 , C12P13/06
摘要： Methods and systems for the production of alcohols are described. A two stage process is utilized, where fermentation in a first stage produces an intermediate product, such as an amino acid or organic acid, from a carbon containing feedstock. A second stage produces alcohol by fermentation of this intermediate product.
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