METHOD TO MONITOR DRUG EFFICACY IN DIABETIC PATIENTS USING AN ASSAY FOR 1,5-ANHYDRO-D-GLUCITOL
    1.
    发明申请
    METHOD TO MONITOR DRUG EFFICACY IN DIABETIC PATIENTS USING AN ASSAY FOR 1,5-ANHYDRO-D-GLUCITOL 审中-公开
    使用1,5-脱水-D-GLUCITOL的测定方法监测糖尿病患者的药物效果

    公开(公告)号:US20100047762A1

    公开(公告)日:2010-02-25

    申请号:US12531426

    申请日:2008-03-20

    IPC分类号: C12Q1/00

    摘要: HbA1c measurement is a critical component of diabetes management; however, a key limitation of HbA1c as a measure of glycemia is the lack of timeliness—it does not detect underlying blood glucose excursion levels in moderately controlled diabetic patients (HbA1c

    摘要翻译: HbA1c测量是糖尿病管理的关键组成部分; 然而,作为血糖测量的HbA1c的一个关键限制是缺乏及时性 - 它不会检测中度控制性糖尿病患者的基础血糖偏移水平(HbA1c <8),因为它是较长时间内测量的平均血糖水平, 术语。 HbA1c也可以在两到三个月内平均低血糖和高血糖症; 因此,它不足以反映餐后高血糖症的改善。 1,5-AG也是一个较短的一到两周时间范围内血糖控制的标志,但与HbA1c的机制不同。 鉴于1,5-AG的独特的生物学和生理学特征,它对高血糖症的急性和短暂性发作敏感,因此是葡萄糖偏移的更好指标。 肽基糖尿病药物如普兰林肽和艾塞那肽具有独特的作用机制,并且这些药物的血糖作用未被HbA1c充分显示。 葡萄糖游离的有效措施1,5-AG揭示了这些药物的潜在治疗作用,可以帮助调节剂量。

    Sanitary earthen products
    2.
    发明授权
    Sanitary earthen products 有权
    卫生陶土制品

    公开(公告)号:US06514622B1

    公开(公告)日:2003-02-04

    申请号:US09762144

    申请日:2001-06-04

    IPC分类号: B32B1504

    摘要: Disclosed is a sanitary ware which has a self-cleaning function for releasing carboxyl-containing greasy stains or soils, such as fatty acids, fatty esters, metallic soaps (scum of soaps), proteins, amino acids, bacteria, and fungi, and deposited stains or soils, such as water scale and urinary calculi. This sanitary ware comprises at least a sanitary ware body and a glaze layer as an outermost layer of the sanitary ware, a monovalent metal component and/or a metal component having a measure of the electronegativity based on Pouling's rule of not more than 1 being provided so as to be releasable evenly and continuously, over the whole surface of the glaze layer as the outermost layer, in such an amount large enough to impart a self-cleaning function for releasing stains or soils to the surface of the glaze layer as the outermost layer, the metal component being suppliable from the glaze layer as the outermost layer and/or the sanitary ware body to the whole surface of the outermost layer. The sanitary ware is advantageous in that stains or soils on the sanitary ware can be simply removed, for example, by running water without using any surfactant and without strongly scrubbing the surface of the sanitary ware by a scrubbing brush or a cleaning brush.

    摘要翻译: 公开了一种卫生洁具,其具有用于释放含羧基的油脂污渍或污垢如脂肪酸,脂肪酸酯,金属皂(肥皂),蛋白质,氨基酸,细菌和真菌的自清洁功能,并沉积 污渍或污垢,如水垢和尿结石。 这种卫生洁具至少包括作为卫生洁具的最外层的卫生洁具主体和釉层,具有基于Pouling规则的不超过1的电负性量度的一价金属成分和/或金属成分 以均匀且连续的方式在作为最外层的釉层的整个表面上以足够大的量赋予自清洁功能,以将污渍或污垢释放到釉层的表面作为最外层 层,作为最外层的釉层提供的金属成分和/或卫生洁具主体到最外层的整个表面。 卫生洁具的优点在于,可以简单地除去卫生洁具上的污渍或污垢,例如通过流水而不使用任何表面活性剂,并且不用擦洗刷或清洁刷强力洗涤卫生洁具的表面。

    Discharge lamp, discharge lamp sealing method, discharge lamp sealing device
    3.
    发明授权
    Discharge lamp, discharge lamp sealing method, discharge lamp sealing device 失效
    放电灯,放电灯密封方式,放电灯密封装置

    公开(公告)号:US06354901B1

    公开(公告)日:2002-03-12

    申请号:US09341788

    申请日:1999-07-16

    IPC分类号: H01J900

    摘要: In a discharge lamp sealing apparatus 30, luminescent substances are charged into an arc tube 11 through an opening 13b thereof, and an electrode member 15 is then inserted into the arc tube 11 through the opening 13b. A lower end of the arc tube 11 is supported by a support jig 57 in a state that a glass ring 16c is placed around the circumference of the opening 13b. The arc tube 11 is set in an air-tight condition by a feeding conduit 51 and inserted into a heating unit 40. The heating unit 40 fuses the glass ring 16c with heat of an infrared lamp and thereby seals the opening 13b. During the sealing process, one end of the arc tube 11 is supported by the support jig 57. The support jig 57 is mainly made of a material having a greater thermal conductivity than that of the material of the arc tube 11, for example, a metal material like Al or Cu. This arrangement enables heat to be readily conducted from the arc tube 11 to the support jig 57 and accordingly prevents a temperature rise in the arc tube 11. This prevents the luminescent substances from being vaporized and released from the arc tube 11.

    摘要翻译: 在放电灯密封装置30中,通过其开口13b将发光物质装入电弧管11中,然后通过开口13b将电极构件15插入电弧管11中。 在玻璃环16c围绕开口13b的周围设置的状态下,电弧管11的下端由支撑夹具57支撑。 电弧管11由供电导管51设定在气密状态,插入加热单元40.加热单元40用红外线灯的热量使玻璃环16c熔合,从而密封开口13b。 在密封过程中,电弧管11的一端由支撑夹具57支撑。支撑夹具57主要由导电率高于电弧管11的材料的材料制成,例如, 金属材料如Al或Cu。 通过这种布置,能够容易地从电弧管11向支撑夹具57传导热量,防止发光管11的温度上升。这样可防止发光物质从电弧管11蒸发掉。

    Gradient function material
    5.
    发明授权
    Gradient function material 失效
    梯度功能材料

    公开(公告)号:US5943546A

    公开(公告)日:1999-08-24

    申请号:US564777

    申请日:1995-11-29

    摘要: A disclosed gradient function material is produced by molding and thereafter firing a slurry which contains a plurality of groups of particles having different specific gravities. The plurality of groups of particles include at least a first group of particles and a second group of particles. The first group of particles comprises a group of non-metal particles having a specific gravity ranging from about 3 to 7 and a maximum particle diameter equal to or smaller than a deflocculation limit, said non-metal particles being made of one or more materials selected from the group consisting of an oxide, a carbide, a nitride, and an oxynitride. The second group of particles comprises a group of metal particles having a specific gravity which is about 1.5 times the specific gravity of said first group of particles, and particle diameters distributed across the deflocculation limit. The gradient function material is manufactured by preparing a slurry containing a plurality of groups of particles and/or a plurality of slurries, and supplying the slurry or slurries into a porous mold to form a deposited region in the porous mold initially primarily influenced by way of attraction of the porous mold and subsequently primarily influenced by a deflocculating effect of the particles in the slurry or slurries or under the influence of the gravity.

    摘要翻译: 所公开的梯度功能材料是通过模塑制造的,然后焙烧含有多组具有不同比重的颗粒的浆料。 多组颗粒包括至少第一组颗粒和第二组颗粒。 第一组颗粒包括比重范围为约3至7并且最大粒径等于或小于抗絮凝极限的一组非金属颗粒,所述非金属颗粒由选自下列的一种或多种材料制成: 由氧化物,碳化物,氮化物和氮氧化物组成的组中。 第二组颗粒包括一组比重约为所述第一组颗粒比重的约1.5倍的金属颗粒,并且分布于整个抗絮凝极限的颗粒直径。 梯度功能材料是通过制备含有多组颗粒和/或多种浆料的浆料制造的,并将浆料或浆料供应到多孔模具中,以在多孔模具中形成沉积区域,最初主要受多孔模具 吸引多孔模具,随后主要受到颗粒在浆料或浆料中或在重力影响下的抗絮凝作用的影响。

    Sanitary ware and process for producing the same
    6.
    发明授权
    Sanitary ware and process for producing the same 失效
    卫生洁具和生产过程

    公开(公告)号:US06548162B1

    公开(公告)日:2003-04-15

    申请号:US09490894

    申请日:2000-01-27

    IPC分类号: B32B516

    摘要: Sanitary wares having a controlled surface are disclosed which are less likely to be stained or soiled and/or possess excellent gloss. The first sanitary ware comprises a sanitary ware body and a surface glaze layer provided on the sanitary ware body, wherein the surface glaze layer has a center line average roughness Ra of less than 0.07 &mgr;m. This sanitary ware is advantageous in that stains or soils are much less likely to be adhered to the surface thereof and, even when adhered to the surface thereof, can be removed by a weak water stream. The second sanitary ware comprises a sanitary ware body and a surface glaze layer provided on the sanitary ware body, wherein the surface glaze layer has a kurtosis Rku of less than 2.70. This sanitary ware advantageously possesses excellent surface gloss. The third sanitary ware comprises a sanitary ware body and a surface glaze layer provided on the sanitary ware body, wherein the surface of the surface glaze layer consists essentially of a vitreous component and is free from silica particles having a particle diameter of not less than 10 &mgr;m. This sanitary ware is advantageous in that stains or soils are less likely to be adhered to the surface thereof.

    摘要翻译: 公开了具有受控表面的卫生用品,其不太可能被染色或污染和/或具有优异的光泽。 第一卫生洁具包括卫生洁具主体和设置在卫生洁具主体上的表面釉层,其中表面釉层的中心线平均粗糙度Ra小于0.07μm。 这种卫生洁具的优点在于,污渍或土壤不太可能附着在其表面上,并且即使当粘附到其表面时也可以通过弱水流除去。 第二卫生洁具包括卫生洁具主体和设置在卫生洁具主体上的表面釉层,其中表面釉层的峭度Rku小于2.70。 这种卫生洁具有利地具有优异的表面光泽度。 第三卫生洁具包括卫生洁具主体和设置在卫生洁具主体上的表面釉层,其中表面釉层的表面主要由玻璃质成分组成,不含粒径不小于10的二氧化硅颗粒 妈妈 这种卫生洁具的优点在于,污渍或污垢不太可能附着在其表面上。

    Gradient function material seal cap for discharge lamp bulb
    7.
    发明授权
    Gradient function material seal cap for discharge lamp bulb 有权
    梯度功能材料密封帽用于放电灯泡

    公开(公告)号:US5972067A

    公开(公告)日:1999-10-26

    申请号:US134823

    申请日:1998-08-17

    摘要: A disclosed gradient function material seal cap for discharge lamp bulb is produced by molding and thereafter firing a slurry which contains a plurality of groups of particles having different specific gravities. The plurality of groups of particles include at least a first group of particles and a second group of particles. The first group of particles comprises a group of non-metal particles having a specific gravity ranging from about 3 to 7 and a maximum particle diameter equal to or smaller than a deflocculation limit, said nonmetal particles being made of one or more materials selected from the group consisting of an oxide, a carbide, a nitride, and an oxynitride. The second group of particles comprises a group of metal particles having a specific gravity which is about 1.5 times the specific gravity of said first group of particles, and particle diameters distributed across the deflocculation limit. The gradient function material seal cap is manufactured by preparing a slurry containing a plurality of groups of particles and/or a plurality of slurries, and supplying the slurry or slurries into a porous mold to form a deposited region in the porous mold initially primarily influenced by way of attraction of the porous mold and subsequently primarily influenced by a deflocculating effect of the particles in the slurry or slurries or under the influence of the gravity.

    摘要翻译: 公开了一种用于放电灯泡的梯度功能材料密封盖,其通过模制并随后焙烧含有多组具有不同比重的颗粒的浆料来制备。 多组颗粒包括至少第一组颗粒和第二组颗粒。 第一组颗粒包括比重范围为约3至7并且最大粒径等于或小于抗絮凝极限的一组非金属颗粒,所述非金属颗粒由选自以下的一种或多种材料制成: 由氧化物,碳化物,氮化物和氮氧化物组成的组。 第二组颗粒包括一组比重约为所述第一组颗粒比重的约1.5倍的金属颗粒,并且分布于整个抗絮凝极限的颗粒直径。 梯度功能材料密封帽是通过制备含有多组颗粒和/或多种浆料的浆料制造的,并将浆料或浆料供应到多孔模具中,以在多孔模具中形成初始主要受 多孔模具的吸引方式,随后主要受到颗粒在浆料或浆料中或在重力影响下的抗絮凝作用的影响。

    Methods of manufacturing gradient function material
    8.
    发明授权
    Methods of manufacturing gradient function material 失效
    制造梯度功能材料的方法

    公开(公告)号:US5653924A

    公开(公告)日:1997-08-05

    申请号:US246134

    申请日:1994-05-19

    摘要: A disclosed gradient function material is produced by molding and thereafter firing a slurry which contains a plurality of groups of particles having different specific gravities. The plurality of groups of particles include at least a first group of particles and a second group of particles. The first group of particles comprises a group of nonmetal particles having a specific gravity ranging from about 3 to 7 and a maximum particle diameter equal to or smaller than a deflocculation limit, said nonmetal particles being made of one or more materials selected from the group consisting of an oxide, a carbide, a nitride, and an oxynitride. The second group of particles comprises a group of metal particles having a specific gravity which is about 1.5 times the specific gravity of said first group of particles, and particle diameters distributed across the deflocculation limit. The gradient function material is manufactured by preparing a slurry containing a plurality of groups of particles and/or a plurality of slurries, and supplying the slurry or slurries into a porous mold to form a deposited region in the porous mold initially primarily influenced by way of attraction of the porous mold and subsequently primarily influenced by a deflocculating effect of the particles in the slurry or slurries or under the influence of the gravity.

    摘要翻译: 所公开的梯度功能材料是通过模塑制造的,然后焙烧含有多组具有不同比重的颗粒的浆料。 多组颗粒包括至少第一组颗粒和第二组颗粒。 第一组颗粒包括比重范围为约3至7并且最大粒径等于或小于抗絮凝极限的一组非金属颗粒,所述非金属颗粒由选自以下的一种或多种材料制成: 的氧化物,碳化物,氮化物和氧氮化物。 第二组颗粒包括一组比重约为所述第一组颗粒比重的约1.5倍的金属颗粒,并且分布于整个抗絮凝极限的颗粒直径。 梯度功能材料是通过制备含有多组颗粒和/或多种浆料的浆料制造的,并将浆料或浆料供应到多孔模具中,以在多孔模具中形成沉积区域,最初主要受多孔模具 吸引多孔模具,随后主要受到颗粒在浆料或浆料中或在重力影响下的抗絮凝作用的影响。