摘要:
A universal linker structure is provided, in which a functional group and activating leaving group are placed on a tether, allowing the placement of an electrophile at the end of any nucleic acid sequence. The electrophile on the tether can react with a second nucleic acid carrying a nucleophile when the two nucleic acids are hybridized near one another, resulting in release of the leaving group, and creation of a functional change. The linker can be designed to destabilize the ligation product without slowing the rate of reaction. This lowers product inhibition, and the target DNA or RNA can become a catalyst for isothermally generating multiple signals for detection. This enhanced signal is demonstrated in solution experiments and in solid supported assays. The universal linkers of the present invention are simple and inexpensive to prepare, and can be appended to any polynucleotide in automated steps on a standard DNA synthesizer.
摘要:
Provided are a fluorescent on/off switchable compound for a gene analysis, which is highly stable and highly sensitive, and enables amplification and observation of a trace gene signal, and a labeling reagent for detection of a bio-related material, which uses the fluorescent on/off switchable compound. A compound represented by the following formula (I′): wherein X is a hydrogen atom or a carboxylic acid-protecting group, Y is a 2,4-dinitrobenzenesulfonyl group, a 2-cyano-4-nitrobenzenesulfonyl group or a 5-nitropyridin-2-ylsulfonyl group, R1, R2, R3 and R4 are each independently a hydrogen atom, a halogen atom, a hydroxyl group, an alkyl group having a carbon number of 1 to 6, an alkoxy group having a carbon number of 1 to 6, an aryl group having a carbon number of 6 to 10, or a cyano group.
摘要:
A recording head includes a recording element substrate having a plurality of discharge ports discharging a liquid and energy generating elements generating energy used to discharge the liquid from the discharge ports; an electrical wiring substrate having an opening portion in which the recording element substrate is provided and for applying a driving signal to the recording element substrate; an electrical connection portion in which an electrode portion of the recording element substrate and an electrode portion of the electrical wiring substrate are electrically connected to each other by a wire; and a sealing material covering and sealing the electrical connection portion. The electrical connection portion is provided with a reference member as a reference of at least one of an upper limit position and a lower limit position of the height of the surface of the sealing material with respect to the thickness direction of the recording element substrate.
摘要:
An electronic money system includes a plurality of electronic money terminals for withdrawing a sum of money which is spent by a user from money data which has been deposited into an information card. Utilization-history data including the number of times the information card has been utilized, and accumulated in the information card is read out at the time when data relating to the spent money is also withdrawn from the information card. Utilization-history data read out from each of the electronic money terminals are gathered and coordinated, so as to coordinate and tabulate the utilization-histories of the information card which has been utilized on any of the plurality electronic money terminals.
摘要:
There is proposed a registration apparatus, a verification apparatus, and a program capable of improving authentication accuracy and an identification data structure capable of improving reliability. A blood vessel line included in an image is divided into a plurality of partial lines on the basis of end points and a diverging point of the blood vessel line. Coefficients of terms corresponding to degrees included in a polynomial equation for an n-th order curve representing each of the partial lines are extracted. Data including points at both ends of each of the partial lines and the coefficients is generated.
摘要:
There is provided an information processing apparatus according to the present invention including a Hough transform unit executing the Hough transformation on a biometrics image which is image information unique to a living body, and a block detection unit detecting whether a block having a predetermined shape is included in a Hough space image which is a Hough-transformed biometrics image, outputting present position information representing a position at which the block is located in the Hough space image when the block is determined to be included in the Hough space image.
摘要:
The present invention provides a method for producing a fatty acid alkyl ester, including step 1 of adding at least one surfactant selected from anionic surfactants, cationic surfactants and amphoteric surfactants and water to a crude fatty acid alkyl ester and stirring to obtain a mixture containing aggregates, and step 2 of separating the aggregates from the mixture from step 1 so that the removal rate of steryl glucoside is 60% or more.
摘要:
A registering device, a collating device, and a program which are capable of improving authentication accuracy and a data configuration of identification data capable of improving reliability are proposed. Parameters representing shapes of partial lines obtained by dividing a blood vessel line appearing in an image by setting end points and branch points of the blood vessel line as reference points are extracted and data including the parameters of the partial lines and positions of points of opposite ends of the partial lines is generated as data identifying a live body.
摘要:
An image processing system and a mask preparation method able to prepare a mask by simple processing and a program executed in such an image processing system are provided. To extract the edges of the image, strings of pixels corresponding to the contours of an object are extracted from the edge extracted image, and border lines for the masking are acquired based on an approximation line thereof.
摘要:
An imaging unit capturing an image of a body surface with near-infrared light while changing a magnification, and generating multiple pieces of near-infrared light imaging data having different magnifications, a vein pattern extraction unit extracting multiple vein patterns corresponding to each of the multiple pieces of the near-infrared light imaging data from each of the multiple pieces of the near-infrared light imaging data, a fractal dimension calculation unit calculating a fractal dimension corresponding to each of the vein patterns for the extracted multiple vein patterns, and a pseudo-vein pattern determination unit determining presence of a pseudo-vein pattern intentionally formed on a part of the captured body surface based on the calculated fractal dimension are provided.