Universal linker compositions for the release or transfer of chemical agents from a polynucleotide
    1.
    发明授权
    Universal linker compositions for the release or transfer of chemical agents from a polynucleotide 有权
    用于从多核苷酸释放或转移化学试剂的通用接头组合物

    公开(公告)号:US07745614B2

    公开(公告)日:2010-06-29

    申请号:US11218961

    申请日:2005-09-01

    摘要: A universal linker structure is provided, in which a functional group and activating leaving group are placed on a tether, allowing the placement of an electrophile at the end of any nucleic acid sequence. The electrophile on the tether can react with a second nucleic acid carrying a nucleophile when the two nucleic acids are hybridized near one another, resulting in release of the leaving group, and creation of a functional change. The linker can be designed to destabilize the ligation product without slowing the rate of reaction. This lowers product inhibition, and the target DNA or RNA can become a catalyst for isothermally generating multiple signals for detection. This enhanced signal is demonstrated in solution experiments and in solid supported assays. The universal linkers of the present invention are simple and inexpensive to prepare, and can be appended to any polynucleotide in automated steps on a standard DNA synthesizer.

    摘要翻译: 提供通用接头结构,其中功能基团和​​活化离去基团置于系链上,允许在任何核酸序列末端放置亲电子试剂。 当两个核酸彼此相互杂交时,系链上的亲电子体可以与携带亲核试剂的第二核酸反应,导致离去基团的释放和功能变化的产生。 连接体可以被设计成使连接产物不稳定而不减慢反应速率。 这降低了产物抑制,目标DNA或RNA可以成为用于等温生成多个用于检测的信号的催化剂。 在溶液实验和固体支持的测定中证明了这种增强的信号。 本发明的通用接头是简单且廉价的制备,并且可以在标准DNA合成仪上以自动步骤附加到任何多核苷酸。

    Fluorescent molecule and method for detecting target nucleic acid
    2.
    发明授权
    Fluorescent molecule and method for detecting target nucleic acid 有权
    荧光分子和检测靶核酸的方法

    公开(公告)号:US08709721B2

    公开(公告)日:2014-04-29

    申请号:US13499826

    申请日:2010-10-01

    IPC分类号: C12Q1/68 C07D409/00 C07H19/04

    摘要: Provided are a fluorescent on/off switchable compound for a gene analysis, which is highly stable and highly sensitive, and enables amplification and observation of a trace gene signal, and a labeling reagent for detection of a bio-related material, which uses the fluorescent on/off switchable compound. A compound represented by the following formula (I′): wherein X is a hydrogen atom or a carboxylic acid-protecting group, Y is a 2,4-dinitrobenzenesulfonyl group, a 2-cyano-4-nitrobenzenesulfonyl group or a 5-nitropyridin-2-ylsulfonyl group, R1, R2, R3 and R4 are each independently a hydrogen atom, a halogen atom, a hydroxyl group, an alkyl group having a carbon number of 1 to 6, an alkoxy group having a carbon number of 1 to 6, an aryl group having a carbon number of 6 to 10, or a cyano group.

    摘要翻译: 提供了用于基因分析的荧光开/关可切换化合物,其高度稳定和高度灵敏,并且能够扩增和观察微量基因信号,以及用于检测生物相关材料的标记试剂,其使用荧光 开/关切换组合。 由下式(I')表示的化合物:其中X是氢原子或羧酸保护基,Y是2,4-二硝基苯磺酰基,2-氰基-4-硝基苯磺酰基或5-硝基吡啶 -2-基磺酰基,R 1,R 2,R 3和R 4各自独立地为氢原子,卤素原子,羟基,碳数为1至6的烷基,碳数为1至 6,碳数为6〜10的芳基或氰基。

    Recording head
    3.
    发明授权
    Recording head 有权
    录音头

    公开(公告)号:US08573748B2

    公开(公告)日:2013-11-05

    申请号:US13030505

    申请日:2011-02-18

    IPC分类号: B41J2/05

    CPC分类号: B41J2/14072

    摘要: A recording head includes a recording element substrate having a plurality of discharge ports discharging a liquid and energy generating elements generating energy used to discharge the liquid from the discharge ports; an electrical wiring substrate having an opening portion in which the recording element substrate is provided and for applying a driving signal to the recording element substrate; an electrical connection portion in which an electrode portion of the recording element substrate and an electrode portion of the electrical wiring substrate are electrically connected to each other by a wire; and a sealing material covering and sealing the electrical connection portion. The electrical connection portion is provided with a reference member as a reference of at least one of an upper limit position and a lower limit position of the height of the surface of the sealing material with respect to the thickness direction of the recording element substrate.

    摘要翻译: 记录头包括具有排出液体的多个排出口的记录元件基板和产生用于从排出口排出液体的能量的能量产生元件; 具有开口部的电布线基板,其中设置有记录元件基板,并且向记录元件基板施加驱动信号; 电连接部,其中记录元件基板的电极部分和电布线基板的电极部分通过电线彼此电连接; 以及覆盖并密封电连接部分的密封材料。 电连接部设置有作为密封材料的表面的高度相对于记录元件基板的厚度方向的上限位置和下限位置中的至少一个的基准构件。

    Electronic money system, electronic money terminal device, and information card
    4.
    发明授权
    Electronic money system, electronic money terminal device, and information card 有权
    电子货币系统,电子货币终端装置和信息卡

    公开(公告)号:US08571988B2

    公开(公告)日:2013-10-29

    申请号:US12026950

    申请日:2008-02-06

    IPC分类号: G06Q40/00

    摘要: An electronic money system includes a plurality of electronic money terminals for withdrawing a sum of money which is spent by a user from money data which has been deposited into an information card. Utilization-history data including the number of times the information card has been utilized, and accumulated in the information card is read out at the time when data relating to the spent money is also withdrawn from the information card. Utilization-history data read out from each of the electronic money terminals are gathered and coordinated, so as to coordinate and tabulate the utilization-histories of the information card which has been utilized on any of the plurality electronic money terminals.

    摘要翻译: 电子货币系统包括多个电子货币终端,用于从存储在信息卡中的货币数据中取出用户所花费的金额。 在与信息卡相关的数据也从信息卡中撤出的情况下,读出包括信息卡被利用次数和信息卡中累积的使用历史数据。 收集和协调从每个电子货币终端读出的利用历史数据,以协调和列出已经在多个电子货币终端中的任何一个上使用的信息卡的利用历史。

    Registration device, checking device, program, and data structure
    5.
    发明授权
    Registration device, checking device, program, and data structure 有权
    注册设备,检查设备,程序和数据结构

    公开(公告)号:US08483449B2

    公开(公告)日:2013-07-09

    申请号:US12600042

    申请日:2008-05-14

    IPC分类号: G06K9/00

    摘要: There is proposed a registration apparatus, a verification apparatus, and a program capable of improving authentication accuracy and an identification data structure capable of improving reliability. A blood vessel line included in an image is divided into a plurality of partial lines on the basis of end points and a diverging point of the blood vessel line. Coefficients of terms corresponding to degrees included in a polynomial equation for an n-th order curve representing each of the partial lines are extracted. Data including points at both ends of each of the partial lines and the coefficients is generated.

    摘要翻译: 提出了能够提高认证精度的登记装置,验证装置和程序以及能够提高可靠性的识别数据结构。 包括在图像中的血管线基于端点和血管线的分叉点被分成多条局部线。 提取与表示各部分线的n次曲线的多项式方程式中包含的度相对应的项的系数。 生成包括每个部分线和系数的两端的点的数据。

    Information processing apparatus, block detection method, and program
    6.
    发明授权
    Information processing apparatus, block detection method, and program 有权
    信息处理装置,块检测方法和程序

    公开(公告)号:US08478070B2

    公开(公告)日:2013-07-02

    申请号:US12802823

    申请日:2010-06-15

    申请人: Hiroshi Abe

    发明人: Hiroshi Abe

    摘要: There is provided an information processing apparatus according to the present invention including a Hough transform unit executing the Hough transformation on a biometrics image which is image information unique to a living body, and a block detection unit detecting whether a block having a predetermined shape is included in a Hough space image which is a Hough-transformed biometrics image, outputting present position information representing a position at which the block is located in the Hough space image when the block is determined to be included in the Hough space image.

    摘要翻译: 提供了一种根据本发明的信息处理装置,包括:霍夫变换单元,其在作为生物体唯一的图像信息的生物特征图像上执行霍夫变换;块检测单元,检测是否包括具有预定形状的块 在作为霍夫变换的生物特征图像的霍夫空间图像中,当确定该块被确定为包括在霍夫空间图像中时,输出表示块位于霍夫空间图像中的位置的当前位置信息。

    Method for producing fatty acid alkyl ester
    7.
    发明授权
    Method for producing fatty acid alkyl ester 有权
    脂肪酸烷基酯的制备方法

    公开(公告)号:US08378133B2

    公开(公告)日:2013-02-19

    申请号:US13148753

    申请日:2010-02-10

    IPC分类号: C11B3/00

    摘要: The present invention provides a method for producing a fatty acid alkyl ester, including step 1 of adding at least one surfactant selected from anionic surfactants, cationic surfactants and amphoteric surfactants and water to a crude fatty acid alkyl ester and stirring to obtain a mixture containing aggregates, and step 2 of separating the aggregates from the mixture from step 1 so that the removal rate of steryl glucoside is 60% or more.

    摘要翻译: 本发明提供一种脂肪酸烷基酯的制造方法,其包括将至少一种选自阴离子表面活性剂,阳离子表面活性剂和两性表面活性剂的表面活性剂和水添加至粗脂肪酸烷基酯的步骤1,并搅拌,得到含有聚集体的混合物 ,步骤2从步骤1的混合物中分离聚集体,使得固体葡糖苷的去除率为60%以上。

    Registering device, checking device, program, and data structure
    8.
    发明授权
    Registering device, checking device, program, and data structure 失效
    注册设备,检查设备,程序和数据结构

    公开(公告)号:US08374419B2

    公开(公告)日:2013-02-12

    申请号:US12600030

    申请日:2008-05-14

    IPC分类号: G06K9/00

    摘要: A registering device, a collating device, and a program which are capable of improving authentication accuracy and a data configuration of identification data capable of improving reliability are proposed. Parameters representing shapes of partial lines obtained by dividing a blood vessel line appearing in an image by setting end points and branch points of the blood vessel line as reference points are extracted and data including the parameters of the partial lines and positions of points of opposite ends of the partial lines is generated as data identifying a live body.

    摘要翻译: 提出了能够提高认证精度的登记装置,对照装置和程序以及能够提高可靠性的识别数据的数据配置。 提取表示通过将血管线的终点和分支点设定为参照点而将图像中出现的血管线划分而得到的部分线的形状的参数,包括部分线的参数和相对端点的位置的数据 的部分行的数据被生成为识别活体的数据。

    Image processing system, mask fabrication method, and program
    9.
    发明授权
    Image processing system, mask fabrication method, and program 有权
    图像处理系统,掩模制作方法和程序

    公开(公告)号:US08311332B2

    公开(公告)日:2012-11-13

    申请号:US11718784

    申请日:2006-08-31

    申请人: Hiroshi Abe

    发明人: Hiroshi Abe

    IPC分类号: G06K9/00

    摘要: An image processing system and a mask preparation method able to prepare a mask by simple processing and a program executed in such an image processing system are provided. To extract the edges of the image, strings of pixels corresponding to the contours of an object are extracted from the edge extracted image, and border lines for the masking are acquired based on an approximation line thereof.

    摘要翻译: 提供了能够通过简单处理来制备掩模的图像处理系统和掩模准备方法以及在这种图像处理系统中执行的程序。 为了提取图像的边缘,从边缘提取图像提取与对象轮廓对应的像素串,并且基于其近似线获取用于掩蔽的边界线。

    Vein pattern management system, vein pattern registration apparatus, vein pattern authentication apparatus, vein pattern registration method, vein pattern authentication method, program, and vein data configuration
    10.
    发明授权
    Vein pattern management system, vein pattern registration apparatus, vein pattern authentication apparatus, vein pattern registration method, vein pattern authentication method, program, and vein data configuration 失效
    静脉图案管理系统,静脉图案登记装置,静脉图案认证装置,静脉图案登记方法,静脉图案认证方法,程序和静脉数据配置

    公开(公告)号:US08275174B2

    公开(公告)日:2012-09-25

    申请号:US12600069

    申请日:2008-05-13

    申请人: Hiroshi Abe

    发明人: Hiroshi Abe

    IPC分类号: G06K9/00

    摘要: An imaging unit capturing an image of a body surface with near-infrared light while changing a magnification, and generating multiple pieces of near-infrared light imaging data having different magnifications, a vein pattern extraction unit extracting multiple vein patterns corresponding to each of the multiple pieces of the near-infrared light imaging data from each of the multiple pieces of the near-infrared light imaging data, a fractal dimension calculation unit calculating a fractal dimension corresponding to each of the vein patterns for the extracted multiple vein patterns, and a pseudo-vein pattern determination unit determining presence of a pseudo-vein pattern intentionally formed on a part of the captured body surface based on the calculated fractal dimension are provided.

    摘要翻译: 一种成像单元,在改变放大倍率的同时,用近红外光拍摄体表的图像,并且生成具有不同倍率的多个近红外光成像数据;静脉图案提取单元,提取与多个 来自多个近红外光成像数据中的每一个的近红外光成像数据的分片维数计算单元,计算与提取的多个静脉图案的每个静脉图案对应的分形维数,以及伪 提供了基于所计算的分形维数来确定有意形成在所捕获的体表面的一部分上的伪静脉图案的存在的印模图案确定单元。