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1.发明授权
公开(公告)号：US4601986A
公开(公告)日：1986-07-22
申请号：US518778
申请日：1983-07-29
申请人： Eugene H. Wegner , Lucas K. Shay
发明人： Eugene H. Wegner , Lucas K. Shay
CPC分类号： C12N1/08 , C12N1/005 , C12N1/32 , Y10S435/804 , Y10S435/822 , Y10S435/823 , Y10S435/83 , Y10S435/832 , Y10S435/84 , Y10S435/843 , Y10S435/848 , Y10S435/858 , Y10S435/859 , Y10S435/867 , Y10S435/872 , Y10S435/874 , Y10S435/886 , Y10S435/908
摘要： A nucleic acid-reduced substantially allergen-free single cell protein product is obtained by culturing a yeast, fungi or bacterium on an ultra-low sulfate medium, treating the produced cells with a base at a pH of about 9.5 with moderate heat, thereafter treating the base-treated cells with acid to a pH of about 4 with moderate heat, and treating the base-treated acid-treated cells with a relatively high temperature short time heat shock, followed by extrusion. Optionally, the extruded product is annealed.
摘要翻译： 通过在超低硫酸盐培养基上培养酵母，真菌或细菌获得核酸减少的基本上无变应原的单细胞蛋白质产物，用温热处理pH约9.5的碱处理生成的细胞，然后处理 碱处理的细胞用酸加热至约4℃，中等加热，并用相对较高温度的短时间热休克处理碱处理的酸处理细胞，然后挤出。 任选地，挤出产品被退火。
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公开(公告)号：US5177003A
公开(公告)日：1993-01-05
申请号：US615541
申请日：1990-11-19
CPC分类号： C12N1/00 , A23L33/14 , C12N1/16 , Y10S435/804
摘要： A process is disclosed for improving the flavor of protein products derived from microorganisms which comprises heat treating the microorganism and then drying same in the absence of a centrifugation. Optionally, the microorganism can be cultured in the presence of a flavor enhancing additive.
摘要翻译： 公开了一种用于改善由微生物衍生的蛋白质产品的风味的方法，其包括热处理微生物，然后在不存在离心的情况下干燥。 任选地，可以在风味增强添加剂的存在下培养微生物。
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公开(公告)号：US4439525A
公开(公告)日：1984-03-27
申请号：US300521
申请日：1981-09-09
申请人： Lucas K. Shay , Eugene H. Wegner
发明人： Lucas K. Shay , Eugene H. Wegner
CPC分类号： C12R1/84 , C12N1/16 , C12N1/32 , C12P13/12 , Y10S435/804 , Y10S435/938
摘要： Mutant yeasts of the strain Pichia pastoris have been developed which contain relatively high levels of methionine. These high methionine content Pichia pastoris mutants grow on an oxygenated hydrocarbon such as methanol, to produce improved amino acid balance single-cell protein product eliminating or reducing the need to supplement single-cell protein with methionine when used as food supplements.
摘要翻译： 已经开发了含有相对高水平甲硫氨酸的巴斯德毕赤酵母菌株的突变酵母。 这些高甲硫氨酸含量的巴斯德毕赤酵母突变体在含氧的烃如甲醇上生长，以产生改善的氨基酸平衡单细胞蛋白产物，当用作食品补充剂时，消除或减少了用甲硫氨酸补充单细胞蛋白的需要。
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4.发明授权
公开(公告)号：US4414329A
公开(公告)日：1983-11-08
申请号：US316164
申请日：1981-10-29
申请人： Eugene H. Wegner
发明人： Eugene H. Wegner
CPC分类号： C12N1/28 , C12N1/16 , C12N1/32 , Y10S435/923 , Y10S435/924 , Y10S435/93 , Y10S435/938 , Y10S435/94 , Y10S435/944
摘要： A method of high cellular density yeast fermentation at high mineral salts feed to and maintained in the ferment.Single cell protein (SCP) is produced in an aerobic fermentation process at high yields under high cell density conditions employing media of high mineral salts concentration. Novel Pichia pastoris and Hansenula polymorpha yeasts are disclosed.
摘要翻译： 一种在高矿物质盐中高细胞密度酵母发酵的方法，并将其保持在发酵中。 在高细胞密度条件下，使用高矿物盐浓度的培养基，在好氧发酵过程中以高产量生产单细胞蛋白（SCP）。 公开了新型巴斯德毕赤酵母和汉逊酵母多形酵母。
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5.发明授权Treatment of make-up water for use in a fermentation process for growth of yeast cells requiring growth factors 失效处理补充水用于需要生长因子的酵母细胞生长的发酵过程中
公开(公告)号：US4226939A
公开(公告)日：1980-10-07
申请号：US875667
申请日：1978-02-06
申请人： Eugene H. Wegner
发明人： Eugene H. Wegner
CPC分类号： C12N1/32 , C12N1/00 , C12N1/16 , Y10S435/804 , Y10S435/818 , Y10S435/822 , Y10S435/911
摘要： Growth of yeasts requiring organic growth factors such as vitamins in an aerobic fermentation process is improved by dechlorination of residual chlorine from residual chlorine-containing make-up water.
摘要翻译： 在需氧发酵过程中需要有机生长因子如维生素的酵母的生长通过从残余的含氯补充水中除去残留的氯来改善。
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公开(公告)号：US4970167A
公开(公告)日：1990-11-13
申请号：US181452
申请日：1988-04-14
CPC分类号： B01D19/0063 , B01D19/0047 , C12M29/06 , C12M29/18 , C12M29/20 , Y10S435/812 , Y10S435/818 , Y10S435/819
摘要： A post-fermentation degassing technique and apparatus are provided which is directed for use in degassing foamed fermentation broths containing cultured microorganisms. Such a broth is charged while pressurized first through a heat exchanger to cool same, and then through a nozzle means to form a spray suspension in a gaseous spray chamber located in a gravitationally upper part of a degassing vessel. The spray chamber is vented to the atmosphere. The spray suspension is coalesced to form a bulk liquid phase located in a gravitationally lower portion of the degassing vessel whereby the unpon surface of such bulk liquid phase forms the bottom surface of such spray chamber. The nozzle means is so oriented that the spray suspension therefrom is downwardly directed towards the surface of the bulk liquid phase and the layer of foam characteristically formed thereon.
摘要翻译： 提供了一种发酵后脱气技术和装置，其被引导用于脱气含有培养的微生物的发泡发酵液。 在首先通过热交换器加压的同时对这种肉汤进行加料，以将其冷却，然后通过喷嘴装置在位于脱气容器的重力上部的气体喷雾室中形成喷雾悬浮液。 喷雾室通向大气。 喷雾悬浮液被聚结以形成位于脱气容器的重力下部的本体液相，由此这种大量液相的未表面形成这种喷雾室的底表面。 喷嘴装置被定向成使得其喷雾悬浮液向下指向主体液相的表面，并且特征地形成在其上的泡沫层。
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7.再颁专利
公开(公告)号：USRE30543E
公开(公告)日：1981-03-10
申请号：US761171
申请日：1977-01-21
摘要： A process for the production of microbial cells by fermenting a carbonaceous material in a foam fermenter containing an oxygen-enriched nutrient medium. The process uses a source of carbon which is assimilable by the microorganism for the production of the microbial cells. The microbial cells are separated and removed from the foam fermenter for use as a food product high in protein content. .Iadd.
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公开(公告)号：US4670397A
公开(公告)日：1987-06-02
申请号：US826424
申请日：1986-02-05
申请人： Eugene H. Wegner , Harold R. Hunt
发明人： Eugene H. Wegner , Harold R. Hunt
CPC分类号： B01J19/18 , B01F15/066 , B01F3/04531 , C12M41/02 , C12M41/24 , F24J3/00 , B01F7/00633 , B01J2219/00081 , Y10S435/804
摘要： Fermentation apparatus useful for conducting aerobic fermentations of microbial cells, particularly at high productivities, is disclosed.
摘要翻译： 公开了用于进行微生物细胞的需氧发酵的发酵装置，特别是在高生产率下。
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公开(公告)号：US3982998A
公开(公告)日：1976-09-28
申请号：US530422
申请日：1974-12-06
CPC分类号： C12N1/34 , C12M21/12 , C12M27/22 , C12M27/24 , C12M41/02 , C12N1/32 , Y10S435/804 , Y10S435/874 , Y10S435/93
摘要： A process for the production of microbial cells by fermenting a carbonaceous material in a foam fermenter containing an oxygen-enriched nutrient medium. The process uses a source of carbon which is assimilable by the microorganism for the production of the microbial cells. The microbial cells are separated and removed from the foam fermenter for use as a food product high in protein content.
摘要翻译： 一种通过在含有富氧营养培养基的泡沫发酵罐中发酵碳质材料来生产微生物细胞的方法。 该方法使用微生物可同化的碳源来生产微生物细胞。 将微生物细胞从泡沫发酵罐中分离并除去，用作蛋白质含量高的食品。
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公开(公告)号：US5266481A
公开(公告)日：1993-11-30
申请号：US531286
申请日：1990-05-31
CPC分类号： B01D19/0063 , B01D19/0047 , C12M29/06 , C12M29/18 , C12M29/20 , Y10S435/812 , Y10S435/813 , Y10S435/819
摘要： A post-fermentation degassing technique is provided which is directed for use in degassing foamed fermentation broths containing cultured microorganisms. Such a broth is charged while pressurized first through a heat exchanger to cool same, and then through a nozzle to form a spray suspension in a gaseous spray chamber located in a gravitationally upper part of a degassing vessel. The spray chamber is vented to the atmosphere. The spray suspension is coalesced to form a bulk liquid phase located in a gravitationally lower portion of the degassing vessel whereby the unpon surface of such bulk liquid phase forms the buttom surface of such spray chamber. The nozzle is so oriented that the spray suspension therefrom is downwardly directed towards the surface of the bulk liquid phase and the layer of foam characteristically formed thereon.
摘要翻译： 提供了一种发酵后脱气技术，其用于脱气含有培养的微生物的发泡发酵液。 在首先通过热交换器加压的同时加入这种肉汤，以冷却它们，然后通过喷嘴在位于脱气容器的重力上部的气体喷雾室中形成喷雾悬浮液。 喷雾室通向大气。 喷雾悬浮液聚结形成位于脱气容器的重力下部的本体液相，由此这种大量液相的不连续表面形成这种喷雾室的表面。 喷嘴如此取向，使得其喷雾悬浮液向下指向主体液相的表面，并且特征地形成在其上的泡沫层。
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