公开(公告)号：US20020076772A1

公开(公告)日：2002-06-20

申请号：US08680139

申请日：1996-07-15

发明人： MYRIAM ELSEVIERS ,  HARALD W. W. ROPER

IPC分类号： C12P007/18

CPC分类号： C07C29/56 ,  C07B2200/07 ,  C12P7/18 ,  Y10S435/921 ,  Y10S435/93 ,  Y10S435/938 ,  Y10S435/94 ,  Y10S435/944 ,  C07C31/18

摘要： The present invention relates to a process for the production of xylitol. Specifically the process comprises two reaction steps. The first step is the fermentative conversion of a hexose to a pentitol. The second step is the catalytic chemical isomerisation of the pentitol to xylitol. Optionally, the xylitol is separated from the other pentitols.

摘要翻译： 本发明涉及生产木糖醇的方法。 具体地说，该方法包括两个反应步骤。 第一步是将己糖发酵转化为戊糖醇。 第二步是将戊糖醇催化化学异构化成木糖醇。 任选地，将木糖醇与其它戊五醇分离。

公开(公告)号：US5627056A

公开(公告)日：1997-05-06

申请号：US386140

申请日：1995-02-09

申请人： John Casey ,  Peter S. Cheetham ,  Peter C. Harries ,  Della Hyliands ,  John T. Mitchell ,  Anthony V. Rawlings

发明人： John Casey ,  Peter S. Cheetham ,  Peter C. Harries ,  Della Hyliands ,  John T. Mitchell ,  Anthony V. Rawlings

IPC分类号： A61K8/00 ,  A61K8/14 ,  A61K8/30 ,  A61K8/31 ,  A61K8/42 ,  A61K8/46 ,  A61K8/49 ,  A61K8/68 ,  A61K8/89 ,  A61K8/891 ,  A61Q3/00 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q7/00 ,  A61Q19/00 ,  C07C231/02 ,  C07C231/12 ,  C07C235/08 ,  C07C235/28 ,  C07H15/04 ,  C07H15/10 ,  C12P13/00 ,  C12R1/78 ,  C12P7/64 ,  C12N1/00 ,  C12N1/14

CPC分类号： C07H15/04 ,  A61K8/68 ,  A61Q19/00 ,  A61Q3/00 ,  A61Q5/00 ,  C07C231/02 ,  C07C235/08 ,  C07C235/28 ,  C07H15/10 ,  C12P13/001 ,  C12P13/02 ,  A61K2800/85 ,  A61Q19/007 ,  A61Q19/08 ,  Y10S435/93

摘要： An efficient method of producing phytosphingosine-containing ceramide one comprising: (a) obtaining a phytosphingosine base from tetraacetylphytosphingosine (TAPS) by a deacetylation reaction wherein the TAPS is produced by fermentation of cells of the F-60-10 mating type strain of Hansenula ciferrii using a fed-batch mode and a non-fermentable carbon source; and (b) coupling together the phytosphingosine base and a fatty acid/.omega.-hydroxy fatty acid component wherein the .omega.-hydroxy fatty acid component is prepared by a process which includes Kolbe synthesis.

摘要翻译： 一种生产含有植物鞘氨醇的神经酰胺的有效方法，其特征在于：（a）通过脱乙酰化反应从四乙酰鞘氨醇（TAPS）获得植物鞘氨醇碱，其中TAPS是通过发酵F-60-10交配型汉逊酵母菌株 使用补料分批模式和不可发酵碳源; 和（b）将植物鞘氨醇碱和脂肪酸/ω-羟基脂肪酸组分偶联在一起，其中ω-羟基脂肪酸组分通过包括Kolb + E，acu e + EE合成的方法制备。

公开(公告)号：US5234827A

公开(公告)日：1993-08-10

申请号：US47658

申请日：1987-05-08

申请人： G. Wesley Hatfield ,  Dane A. Hoiberg

发明人： G. Wesley Hatfield ,  Dane A. Hoiberg

IPC分类号： C12M1/40 ,  C12N9/04 ,  C12P3/00 ,  C12P7/24

CPC分类号： C12N9/0006 ,  C12M21/18 ,  C12P3/00 ,  C12P7/24 ,  Y10S435/818 ,  Y10S435/93 ,  Y10S435/938

摘要： A process is disclosed for enzymatically converting lower alkyl alcohols to corresponding aldehydes and hydrogen peroxide in the presence of oxygen under process conditions which increase the catalytic capacity of alcohol oxidase enzymes. Such process conditions involve low temperatures, high substrate concentrations and an enriched supply of oxygen. Enzymes may be used in the form of whole cells, a soluble cell free extract or a highly purified fraction, and the process may be employed in batch or continuous operation.

摘要翻译： 公开了一种在氧气存在下将低级烷基醇酶化为相应的醛和过氧化氢的方法，其在加工条件下提高了醇氧化酶的催化能力。 这种工艺条件包括低温，高底物浓度和富氧供应。 酶可以以全细胞，可溶性无细胞提取物或高纯度级分的形式使用，并且该方法可以分批或连续操作使用。

公开(公告)号：US4874695A

公开(公告)日：1989-10-17

申请号：US703644

申请日：1985-02-21

申请人： David H. Pincus

发明人： David H. Pincus

IPC分类号： C12Q1/04

CPC分类号： C12Q1/04 ,  Y10S435/81 ,  Y10S435/922 ,  Y10S435/924 ,  Y10S435/93 ,  Y10S435/942 ,  Y10S435/944 ,  Y10S435/946

摘要： Rapid identification of different species of microorganism selected from fungi and yeast like algae is accomplished by culturing the microorganism for several hours under normal conditions on a non-inhibitory mycological medium which stimulates the microorganism to make characteristic enzymes by which the microorganism can be identified, distributing the culture (in suspension) onto several supports containing different substrates which are capable of reacting with the enzymes so produced by the different species of microorganisms; and rapidly incubating the admixture to produce a distinctly colored or colorable reaction product.

摘要翻译： 通过在正常条件下在非抑制性真菌学培养基上培养微生物几个小时来快速鉴定选自真菌和酵母样藻类的微生物，该非抑制性真菌学培养基刺激微生物制备鉴定微生物的特征性酶，分布 将培养物（悬浮液）置于含有不同底物的若干载体上，所述底物能够与由不同种类的微生物产生的酶反应; 并快速孵育混合物以产生明显着色或可着色的反应产物。

公开(公告)号：US4261420A

公开(公告)日：1981-04-14

申请号：US34796

申请日：1979-04-30

申请人： Donald O. Hitzman

发明人： Donald O. Hitzman

IPC分类号： C09K8/90 ,  C12N1/32 ,  E21B43/16 ,  A23J1/18 ,  C12P21/00 ,  E21B43/22 ,  E21B43/40

CPC分类号： C09K8/905 ,  C12N1/32 ,  E21B43/164 ,  Y02P90/70 ,  Y10S435/804 ,  Y10S435/923 ,  Y10S435/924 ,  Y10S435/93 ,  Y10S435/938

摘要： A single cell protein plant is operated to produce high density cell growth and a substantially pure stream of generally high pressure carbon dioxide for further use, for example, in enhanced oil recovery operations. The plant employs an air separator producing substantially pure streams of oxygen and nitrogen. The oxygen stream is used to enrich a carrier fluid and used for aeration of the fermenter. The off-gases from the fermenter are separated into a generally high pressure, substantially pure carbon dioxide stream which can be used for enhanced oil recovery and a residual recycle stream to which oxygen is again added and which is returned to the fermenter. The single cell protein is dried and further processed as required for human or animal consumption.

摘要翻译： 操作单细胞蛋白质植物以产生高密度细胞生长和基本上纯的一般高压二氧化碳流，用于进一步使用，例如在增强的采油操作中。 该工厂使用空气分离器，产生基本上纯净的氧气和氮气流。 氧气流用于富集载体流体并用于发酵罐的通气。 来自发酵罐的废气被分离成通常高压，基本上纯的二氧化碳流，其可用于增强油采收和再次添加氧并将其返回到发酵罐的残余循环物流。 将单细胞蛋白质干燥并根据人或动物消费的需要进一步加工。

公开(公告)号：US3982998A

公开(公告)日：1976-09-28

申请号：US530422

申请日：1974-12-06

申请人： Donald O. Hitzman ,  Eugene H. Wegner

发明人： Donald O. Hitzman ,  Eugene H. Wegner

IPC分类号： C12M1/04 ,  C12M1/08 ,  C12N1/32 ,  C12N1/34 ,  C12C11/14 ,  C12B1/08 ,  C12C11/10

CPC分类号： C12N1/34 ,  C12M21/12 ,  C12M27/22 ,  C12M27/24 ,  C12M41/02 ,  C12N1/32 ,  Y10S435/804 ,  Y10S435/874 ,  Y10S435/93

摘要： A process for the production of microbial cells by fermenting a carbonaceous material in a foam fermenter containing an oxygen-enriched nutrient medium. The process uses a source of carbon which is assimilable by the microorganism for the production of the microbial cells. The microbial cells are separated and removed from the foam fermenter for use as a food product high in protein content.

摘要翻译： 一种通过在含有富氧营养培养基的泡沫发酵罐中发酵碳质材料来生产微生物细胞的方法。 该方法使用微生物可同化的碳源来生产微生物细胞。 将微生物细胞从泡沫发酵罐中分离并除去，用作蛋白质含量高的食品。

公开(公告)号：US3887435A

公开(公告)日：1975-06-03

申请号：US44029174

申请日：1974-02-07

申请人： AJINOMOTO KK

发明人： NAKAMURA JUNJI ,  MIYASHIRO SHIGEYOSHI ,  OKADA HIROSHI

IPC分类号： C12N1/16 ,  C12C11/08

CPC分类号： C12N1/16 ,  Y10S435/804 ,  Y10S435/911 ,  Y10S435/921 ,  Y10S435/923 ,  Y10S435/93 ,  Y10S435/938 ,  Y10S435/94 ,  Y10S435/941 ,  Y10S435/944

摘要： Many yeasts are capable of growing in culture media which contain propionate and n-butyrate ions as the principal or the sole significant source of carbon. Propionic and butyric acid are waste products of the petrochemical industry, and the yeast cells are a valuable feed supplement.

摘要翻译： 许多酵母能够在含有丙酸盐和正丁酸盐离子作为主要或唯一重要的碳源的培养基中生长。 丙酸和丁酸是石油化学工业的废物，酵母细胞是有价值的饲料添加剂。

公开(公告)号：US3773620A

公开(公告)日：1973-11-20

申请号：US3773620D

申请日：1970-09-24

申请人： KYOWA HAKKO KOGYO KK

发明人： KIMURA K ,  NAKANISHI T

IPC分类号： C12P7/48 ,  C12B1/00

CPC分类号： C12P7/48 ,  Y10S435/83 ,  Y10S435/84 ,  Y10S435/843 ,  Y10S435/913 ,  Y10S435/921 ,  Y10S435/93 ,  Y10S435/933 ,  Y10S435/938 ,  Y10S435/944

摘要： Processes for producing citric acid together with microbial cells as well as producing increased yields of citric acid and/or isocitric acid by fermentation are described. Hydrocarbonassimilating microorganisms are employed in media containing hydrocarbons as the main carbon source. The addition of alcohols, such as C1-C20 saturated alcohols, to the medium permits the accumulation of citric acid together with the obtained microbial cells. The addition of ferrocyanides, such as potassium or sodium ferrocyanide, to the medium enhances the yield of isocitric acid, while the addition of monofluoroacetic acid or a salt thereof to the medium enhances the yield of citric acid.

公开(公告)号：US3579544A

公开(公告)日：1971-05-18

申请号：US3579544D

申请日：1968-05-24

申请人： TAKEDA CHEMICAL INDUSTRIES LTD

发明人： HIRAGA KENTARO ,  ASAKO TSUNEHIKO ,  MIKI TAKUICHI

IPC分类号： C07C169/08

CPC分类号： C07J1/0059 ,  C07J1/007 ,  C07J1/0074 ,  Y10S435/911 ,  Y10S435/921 ,  Y10S435/93 ,  Y10S435/941 ,  Y10S435/944

摘要： A COMPOUND HAVING A 16-(ETHERIFIED OR ESTERIFIED HYDROXY)-17-ACYLOXY-13-SUBSTITUTED GONA-1,3,5(10),8,14PENTAENE NUCLEUS IS OBTAINED BY ALLOWING A COMPOUND HAVING A 17-ACYLOXY-13-SUBSTITUTED 8,14-SECOGONA-1,3,5 (10),9(11),15-PENTAENE-14-ONE NUCLEUS TO CONTACT WITH AN ACID CATALYST IN PRESENCE OF ALCOHOL, PHENOL OR FATTY ACID, AND CONVERTING THE RESULTANT COMPOUND HAVING A 16-(ETHERIFIED OR ESTERIFIED HYDROXY)-17-ACYLOXY-13-SUBSTITUTED GONA-1,3,5(10),8,14-PENTAENE NUCEUS DIRECTLY OR AFTER REDUCTION OF ITS DOUBLE BOND AT THE 8-POSITION OR BANDS AT THE 8- AND 14-POSITIONS, TO A COMPOUND HAVING A 13-(HYDROCARBON SUBSTITUTED)GONAPOLYEN-17-ONE NUCLEUS. IT IS THUS MADE POSSIBLE TO EFFECT THE TOTAL SYNTHESIS OF THE GONA POLYENES (E.G. ESTRONE) VIA A LESSER NUMBER OF STEPS THAN HAS HERETOFORE BEEN POSSIBLE.

公开(公告)号：US3560341A

公开(公告)日：1971-02-02

申请号：US3560341D

申请日：1968-08-15

申请人： BRITISH PETROLEUM CO

发明人： CHAMPAGNAT ALFRED ,  FILOSA JEAN ANTOINE

IPC分类号： C10G32/00 ,  C12N1/26 ,  C12C11/00 ,  A23J1/18 ,  C12D13/06

CPC分类号： C10G32/00 ,  C12N1/26 ,  Y10S435/911 ,  Y10S435/921 ,  Y10S435/923 ,  Y10S435/93 ,  Y10S435/944

摘要： A PROCESSS FOR THE PRODUCTION OF AN EDIBLE YEAST PRODUCT WITH A CONCURRENT DEWAXING OF A PETROLEUM FRACTION CONTAINING INITIALLY FROM 3 TO 45% BY WEIGHT OF N-PARAFFIN, SAID FRACTION FURTHER CONTAINING BRANCHED-CHAIN PARAFFINS, NAPHTHENES AND AROMATICS. SAID PROCESS PRODUCES A DEWAXED GAS-OIL PRODUCT THUS RENDERED MORE SUITABLE FOR INDUSTRIAL USE THROUGH A REDUCED PROPORTION OF N-PARAFFIN AND AN EDIBLE YEAST PRODUCT WHICH IS CULTIVATED AT THE EXPENSE OF THE N-PARAFFIN INITIALLY PRESENT.