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    ADAPTIVE PROGRAMMABLE MODULATION TECHNIQUES FOR MINIATURIZED MEASUREMENT DEVICES
    1.
    发明申请
    ADAPTIVE PROGRAMMABLE MODULATION TECHNIQUES FOR MINIATURIZED MEASUREMENT DEVICES 有权

    公开(公告)号：US20220397548A1

    公开(公告)日：2022-12-15

    申请号：US17776754

    申请日：2020-01-27

    申请人： FemtoDx, Inc.

    发明人： Sudhakar Pamarti ,  Shyamsunder Erramilli ,  Pritiraj Mohanty

    IPC分类号： G01N27/414 ,  G01N27/04

    摘要： Aspects of the present disclosure provide measurement devices and methods for detecting electrical characteristics of devices under test (DUTs), such as semiconductor nanowires. Techniques described herein provide programmable measurement devices that may be implemented in a compact form factor while being able to perform reliable measurements. In some embodiments, measurement devices described herein may be programmed to modulate signals for transmitting to a DUT, and may demodulate signals from the DUTs adaptively using self-programming techniques described herein. Such self-programming may include applying a programmable phase delay to oscillator signals used during demodulation. In some embodiments, such measurement devices may be implemented on a single circuit board, in a single integrated circuit package, or even on a single solid-state semiconductor die. Techniques described herein may enable reliable, inexpensive, and small-scale fluid sample measurement devices.

    Field-controlled sensor architecture and related methods
    6.
    发明授权
    Field-controlled sensor architecture and related methods 有权

    公开(公告)号：US11715772B1

    公开(公告)日：2023-08-01

    申请号：US15691598

    申请日：2017-08-30

    申请人： FemtoDx, Inc.

    发明人： Pritiraj Mohanty ,  Shyamsunder Erramilli

    IPC分类号： H01L29/40 ,  H01L29/786 ,  H01L29/06 ,  G01N27/414 ,  G01N33/543 ,  G01N27/30

    CPC分类号： H01L29/402 ,  G01N27/30 ,  G01N27/4145 ,  G01N33/5438 ,  H01L29/0673 ,  H01L29/78648 ,  H01L29/78696

    摘要： A nanoelectric field effect sensor uses the field created by the surface charge profile of biomolecular binding to modulate the current flowing between a source and a drain. We have shown that a patterned side or top gate can be used to calibrate the biomolecular field modulation. This approach provides an electrical sensitivity characterization of the sensor before exposing it to sample fluid. Furthermore, a side gate or a top gate voltage with the right sign can be used to control the binding event during functionalization or sensing. For instance, a negative gate voltage can prevent binding of negatively charged proteins on a sensor. This approach of electric-field control of binding can be used in a differential sensor configuration as well. For instance, in a two-sensor single-bridge technique, one of the sensors can be exposed to a local electric field to prevent binding events, which can then be used for background cancellation in a second sensor, not exposed to the electric field. Furthermore, this approach can be used to prepare a sensor chip for multiplexing, where different chip areas can be turned on or off by applying local electric fields.