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公开(公告)号:US20080131489A1
公开(公告)日:2008-06-05
申请号:US11793045
申请日:2005-10-26
申请人: Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
发明人: Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
CPC分类号: A61K9/703 , A61K9/7084
摘要: A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt. % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer. A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt. % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
摘要翻译: 适于制备透皮递送装置的复合结构包括:(a)衬垫膜层; (b)含有0至15wt。 乙酸乙烯酯重复单元的含量为%,该层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分和非极性聚合物的组合; 和(c)厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物,其中嵌段共聚物的A链段是苯乙烯链段。 组合物包含1至15wt。 基于不包括任何溶剂的组合物的总重量的乙酸乙烯酯重复单元的百分比。
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公开(公告)号:US20110052789A1
公开(公告)日:2011-03-03
申请号:US12890291
申请日:2010-09-24
申请人: Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
发明人: Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
IPC分类号: B05D3/00
CPC分类号: A61K9/703 , A61K9/7084
摘要: A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer.A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
摘要翻译: 适于制备透皮递送装置的复合结构包括:(a)衬垫膜层; (b)包含乙酸乙烯酯重复单元含量为零至15重量%的容纳层,所述层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分与非极性聚合物的组合; 和(c)厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物,其中嵌段共聚物的A链段是苯乙烯链段。 基于不包括任何溶剂的组合物的总重量,该组合物包含1至15重量%的乙酸乙烯酯重复单元。
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公开(公告)号:US08840920B2
公开(公告)日:2014-09-23
申请号:US12890291
申请日:2010-09-24
申请人: Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
发明人: Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
CPC分类号: A61K9/703 , A61K9/7084
摘要: A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer.A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
摘要翻译: 适于制备透皮递送装置的复合结构包括:(a)衬垫膜层; (b)包含乙酸乙烯酯重复单元含量为零至15重量%的容纳层,所述层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分与非极性聚合物的组合; 和(c)厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物,其中嵌段共聚物的A链段是苯乙烯链段。 基于不包括任何溶剂的组合物的总重量,该组合物包含1至15重量%的乙酸乙烯酯重复单元。
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公开(公告)号:US20130236612A1
公开(公告)日:2013-09-12
申请号:US13822886
申请日:2011-09-13
CPC分类号: B65D81/34 , B32B1/02 , B32B27/08 , B32B27/304 , B32B27/34 , B32B27/36 , B32B2307/306 , B32B2307/31 , B32B2307/738 , B32B2439/70 , B65B1/02 , Y10T428/1334 , Y10T428/31736 , Y10T428/31739 , Y10T428/31786 , Y10T428/31797
摘要: A laminate includes the following substantially coextensive layers in the following order: (a) a non-sealable, self-supporting, thermoformable copolyester film layer having a first surface and a second surface, the second surface constituting an outermost, exposed surface of the laminate; (b) a laminating adhesive layer on the first surface of the thermoformable copolyester film layer; and (c) a self-supporting, thermoformable structural film layer having a first surface and a second surface, the first surface contacting the laminating adhesive layer. Polyethylene terephthalate constitutes at least 80% by weight of the self-supporting thermoformable copolyester film layer; the thermoformable structural film layer includes a polymer selected from the group consisting of polyamides, polypropylene, polyethylene, polyethylene terephthalate, ionomers, ethylene acrylic acid copolymers, ethylene vinyl acetate copolymers, polystyrene, ethylene vinyl alcohol copolymers and polyvinylidene chloride; the thermoformable copolyester film layer, the structural film layer and the laminate each shrink less than 5% in length and width upon exposure to boiling water for five seconds; and the laminate is thermoformable and its chloroform-soluble extractives meet the requirements of paragraph h(1) of 21 CFR §177.1630 as defined herein.
摘要翻译: 层压体按以下顺序包括以下基本上共同延伸的层:(a)具有第一表面和第二表面的不可密封的自支撑的可热成形的共聚酯膜层,所述第二表面构成层压体的最外面的暴露表面 ; (b)可热成型共聚酯膜层的第一表面上的层压粘合剂层; 和(c)具有第一表面和第二表面的自支撑的可热成形的结构膜层,所述第一表面接触层压粘合剂层。 聚对苯二甲酸乙二醇酯构成自支撑热成型共聚酯膜层的至少80重量% 可热成形的结构膜层包括选自聚酰胺,聚丙烯,聚乙烯,聚对苯二甲酸乙二醇酯,离聚物,乙烯丙烯酸共聚物,乙烯乙酸乙烯酯共聚物,聚苯乙烯,乙烯乙烯醇共聚物和聚偏二氯乙烯的聚合物; 可热成型共聚酯膜层,结构膜层和层压体在暴露于沸水中5秒钟时的长度和宽度小于5%; 并且层压板是可热成型的,其氯仿可溶性提取物符合本文定义的21 CFR§177.1630段落h(1)的要求。
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公开(公告)号:US20100221391A1
公开(公告)日:2010-09-02
申请号:US12675262
申请日:2008-08-26
CPC分类号: B32B27/36 , B32B27/08 , B32B2307/308 , B32B2439/70 , B65D81/2015 , B65D81/343 , B65D81/3453 , C08J7/047 , C08J2367/00 , C08J2467/00 , Y02P20/582
摘要: The invention provides an ovenable vacuum skin package for storage and cooking of a food product. The package includes a receptacle and a thermoformable composite polymeric film cover heat-sealed thereto, and the composite polymeric film cover includes: (i) a thermoformable substrate layer comprising a first copolyester material; and (ii) on a surface of the substrate layer, a heat-sealable layer comprising a second copolyester material, the second copolyester material being different from the first copolyester material; wherein i. the receptacle comprises on a surface thereof a sealing region adapted to contact and form a scal with the heat-sealable layer; and ii. both the receptacle and the cover film comply with the requirements of paragraph h(1) of CFR §177.1630.
摘要翻译: 本发明提供了一种用于储存和烹饪食品的可烘烤真空皮肤包装。 该包装包括一个容器和一个热成型的复合聚合物薄膜盖子,其热封在其上,复合聚合薄膜盖包括:(i)包含第一共聚酯材料的可热成型的基底层; 和(ii)在所述基材层的表面上,包含第二共聚酯材料的可热封层,所述第二共聚酯材料不同于所述第一共聚酯材料; 其中i。 容器在其表面上包括适于与可热封层接触并形成刮板的密封区域; 和ii。 容器和覆盖膜均符合CFR§177.1630第h(1)段的要求。
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公开(公告)号:US20100178318A9
公开(公告)日:2010-07-15
申请号:US11793045
申请日:2005-10-26
申请人: Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
发明人: Peter N. Nugara , Bruce C. Begnoche , Stephen K. Franzyshen , Fenghua Deng , Daniel C. Sanders , Christine A. Creegan , Steven R. Cosentino
CPC分类号: A61K9/703 , A61K9/7084
摘要: A composite structure suitable for making transdermal delivery devices includes in sequence: (a) a liner film layer; (b) a containment layer having from zero to 15 wt. % content of vinyl acetate repeating units, the layer including either a thermal bonding copolyester resin or a combination of an ethylene-vinyl acetate component and a nonpolar polymer; and (c) a polyester film layer less than 20 μm in thickness. A drug layer lies either between the liner film layer and the containment layer or within a concave depression in the containment layer. A composition including an ethylene-vinyl acetate component and an ABA block copolymer, wherein the A segments of the block copolymer are styrenic segments, is also provided. The composition includes between 1 and 15 wt. % of vinyl acetate repeating units, based on the total weight of composition exclusive of any solvents.
摘要翻译: 适于制备透皮递送装置的复合结构包括:(a)衬垫膜层; (b)含有0至15wt。 乙酸乙烯酯重复单元的含量为%,该层包括热粘合共聚酯树脂或乙烯 - 乙酸乙烯酯组分和非极性聚合物的组合; 和(c)厚度小于20μm的聚酯薄膜层。 药物层位于衬垫膜层和容纳层之间或位于容纳层中的凹陷凹陷内。 还提供了包含乙烯 - 乙酸乙烯酯组分和ABA嵌段共聚物的组合物,其中嵌段共聚物的A链段是苯乙烯链段。 组合物包含1至15wt。 基于不包括任何溶剂的组合物的总重量的乙酸乙烯酯重复单元的百分比。
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公开(公告)号:US07195804B2
公开(公告)日:2007-03-27
申请号:US10718334
申请日:2003-11-20
CPC分类号: B32B5/02 , B32B27/36 , Y10T428/1303 , Y10T428/1314 , Y10T428/1317 , Y10T428/1359 , Y10T428/31565 , Y10T428/31591 , Y10T428/31616 , Y10T428/31783 , Y10T428/31786 , Y10T442/119 , Y10T442/121 , Y10T442/126 , Y10T442/169 , Y10T442/178 , Y10T442/675
摘要: A paperboard composite for use in packaging applications includes paperboard adhered to a backing structure, providing enhanced wet tear strength. The backing structure includes an oriented polymer film and a reinforcing scrim, bonded together by a thermal bonding layer. In one embodiment of the invention, the parts of the backing structure are of similar chemical composition, thereby facilitating recycling of scraps and other waste.
摘要翻译: 用于包装应用的纸板复合材料包括附着在背衬结构上的纸板,提供增强的湿撕裂强度。 背衬结构包括通过热粘合层粘合在一起的取向聚合物膜和加强稀松布。 在本发明的一个实施方案中,背衬结构的部分具有类似的化学组成,从而有利于废料和其它废物的再循环。
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公开(公告)号:US07157126B2
公开(公告)日:2007-01-02
申请号:US10820549
申请日:2004-04-08
CPC分类号: B32B5/02 , B32B27/36 , Y10T428/1303 , Y10T428/1307 , Y10T428/1317 , Y10T428/1321 , Y10T428/1359 , Y10T428/1362 , Y10T428/1366 , Y10T428/31565 , Y10T442/126 , Y10T442/131 , Y10T442/169 , Y10T442/176 , Y10T442/675
摘要: The invention is a tear-resistant container or bag made with a multilayer film comprising a composite structure of relatively inexpensive polymers and paper. The multilayer composite structure generally consists of an oriented polymer film layer adhered to a reinforcing scrim layer via a thermal bonding layer, to form a backing structure, and at least one paper layer adhered to the backing structure.
摘要翻译: 本发明是一种用多层膜制成的抗撕裂容器或袋,其包含相对便宜的聚合物和纸的复合结构。 多层复合结构通常由经由热粘合层粘附到增强稀松布层的取向聚合物膜层组成,以形成背衬结构,以及粘附到背衬结构的至少一个纸层。
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公开(公告)号:US20090130276A1
公开(公告)日:2009-05-21
申请号:US12092642
申请日:2006-11-08
CPC分类号: B32B27/08 , B32B27/304 , B32B27/306 , B32B27/34 , B32B27/36 , B32B2307/31 , B32B2307/724 , B32B2307/7242 , B32B2307/726 , B32B2307/738 , B32B2327/00 , B32B2367/00 , B32B2377/00 , B32B2435/00 , B32B2439/40 , B32B2439/70 , B65B25/06
摘要: A method of packaging ovenable fish or meat and which comprises the steps of providing a dual-ovenable thermoformable polymeric receiving film having a first and second surface and a dual-ovenable polymeric covering film having a first and second surface, wherein said receiving film consists of a mono-layer polyester or polyamide substrate, an optional barrier layer, and an optional heat-sealable layer which where present constitutes the first surface of the receiving film, wherein said receiving and covering films are separate pieces of film and wherein at least one of said first surfaces of said receiving and covering films is a heat-sealable surface; providing a raised outer portion and an indented central portion in said receiving film by thermoforming; disposing on the first surface of the receiving film a portion of meat or fish; disposing the covering film over the portion of meat or fish such that the first surface of the covering film is disposed towards the first surface of the receiving film; contacting the peripheral portions of the first surface of the receiving film and the first surface of the covering film and forming a heat-seal bond therebetween; and optionally freezing the packaged meat or fish is described.
摘要翻译: 一种包装可烤鱼或肉的方法,其包括以下步骤:提供具有第一和第二表面的双可烘烤的可热成型聚合物接收膜和具有第一和第二表面的双可烘烤聚合物覆盖膜,其中所述接收膜由 单层聚酯或聚酰胺基材,任选的阻隔层和可选的可热封层,其中当前构成接收膜的第一表面,其中所述接收和覆盖膜是分离的薄片,并且其中至少一个 所述接收和覆盖膜的所述第一表面是可热封表面; 通过热成型在所述接收膜中提供凸起的外部部分和凹入的中心部分; 在接收膜的第一表面上放置一部分肉或鱼; 将覆盖膜设置在肉或鱼的部分上,使得覆盖膜的第一表面朝向接收膜的第一表面设置; 使接收膜的第一表面的周边部分和覆盖膜的第一表面接触,并在其间形成热密封接合; 并且任选地冷冻包装的肉或鱼。
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公开(公告)号:US07012032B2
公开(公告)日:2006-03-14
申请号:US10714144
申请日:2003-11-14
IPC分类号: B32B15/001 , B32B27/00 , B32B15/004 , B29D22/00 , B29D23/00
CPC分类号: B32B7/12 , B32B5/02 , B32B7/10 , B32B27/12 , B32B27/36 , B32B2272/00 , B32B2307/518 , B32B2307/5825 , B32B2367/00 , B32B2581/00 , Y10T428/1359 , Y10T428/1362 , Y10T428/28 , Y10T428/31565 , Y10T428/31569 , Y10T442/124 , Y10T442/126 , Y10T442/674
摘要: A tear resistant seal made from a recyclable multilayer structure that consists of an oriented polymer film layer a thermal bonding polymer layer on the oriented polymer layer inner surface substantially coextensive thereto, and a reinforcing scrim polymer layer also having an inner surface adjacent and substantially coextensive with the thermal bonding polymer layer. The polymer film layer and the bonding polymer layer are co-extruded layers having a chemical composition that permits recycling without separating the layers. The scrim layer also has a similar chemical composition, permitting recycling following lamination, thereby permitting the recovery of waste material during production runs by the simple recycling of the complete laminated structure.
摘要翻译: 由可回收多层结构制成的抗撕裂密封件,其由定向聚合物膜层组成,所述聚合物膜层在其基本上共同延伸的取向聚合物层内表面上的热粘合聚合物层,以及还具有与表面相邻并基本上共同延伸的内表面的增强稀松布聚合物层 热粘合聚合物层。 聚合物膜层和接合聚合物层是具有允许循环而不分离层的化学组成的共挤出层。 稀松布层还具有类似的化学组成,允许层压后再循环,从而允许通过完全层压结构的简单再循环在生产运行期间回收废料。
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