摘要:
Novel methods of medical treatment and/or inhibition of development of diseases are disclosed for diseases that are sensitive to androgenic or estrogenic activity. The treatments utilize inhibitors of type 5 and/or type 3 17&bgr;-hydroxysteroid dehydrogenase. Novel inhibitors of type 5 17&bgr;-hydroxysteroid dehydrogenase are also disclosed, as are novel inhibitors of type 3 17&bgr;-hydroxysteroid dehydrogenase.
摘要:
A method of treatment of breast cancer in susceptible animals whose ovarian hormonal secretions were previously blocked by surgical or chemical means, e.g., by use of an LH-RH agonist, e.g., [D-Trp.sup.6, des-Gly-NH.sub.2.sup.10 ]LH-RH ethylamide with a combination therapy comprising administering an antiandrogen, e.g., flutamide and an antiestrogen, e.g., Tamoxifen, pharmaceutical compositions useful for such treatment and two and three component pharmaceutical kits containing such compositions are disclosed.
摘要:
A runner, a suspended ceiling system, and a method of installing a suspended ceiling, the runner having a base with two laterally opposite flanges for supporting ceiling tiles, a hinged web connected to the base between the flanges so as to be foldable between a flat configuration with the web folded against one of the flanges and an inverted-T configuration with the web normal to the base for suspension and use, the hinged web allowing for economies is shipping when compared to conventional rigid inversed-T shaped runners.
摘要:
The adaptation of a regular pocket size computer for use by a visually impaired person is provided. A framework is firstly provided for building adapted applications, having adapted input and output services, a system resources library including tools for interacting with these adapted services and an adaptation library. A tactile keyboard is further provided to allow data entry through the screen interface of the computer. The tactile keyboard includes a membrane having raised keys on one side and corresponding screen activating tips on the other. Means for mounting the keyboard above the computer with the screen activating tips positioned in contact less alignment with the corresponding selected areas of the screen interface are also provided.
摘要:
Disclosed herein are derivatives of 5-(lower alkyl)-7-amino-2,3-dihydro-1,4-phthalazinedione having substituents on the amino group. The derivatives have luminescent properties which render them useful as analytical tools in clinical chemistry. Adaptation of the derivatives for luminescent immunoassay provides valuable reagents and assays with outstanding sensitivity.
摘要:
A runner, a suspended ceiling system, and a method of installing a suspended ceiling, the runner having a base with two laterally opposite flanges for supporting ceiling tiles, a hinged web connected to the base between the flanges so as to be foldable between a flat configuration with the web folded against one of the flanges and an inverted-T configuration with the web normal to the base for suspension and use, the hinged web allowing for economies is shipping when compared to conventional rigid inversed-T shaped runners.
摘要:
The waved wood assembly can have a flexible support layer onto the face(s) of which one or more wood sheet layer(s) are adhered by an adhesive. The waved wood product can maintain its waved shape when freestanding. It can exhibit significant elasticity characteristics. It can have very accentuated waves, i.e. waves that span a greater thickness for a given number of waves per unit of dimension.
摘要:
A vehicle security system for controlling the operation of a vehicle. The security system includes a controller and a concealed proximity sensor that provides an input to the controller. The proximity sensor is activated by the presence of a body within a defined detection zone in the interior of the vehicle. The controller receives additional inputs from additional devices and toggles through a plurality of security states in which different levels of activation and immobilization are triggered depending upon user input and upon the specific inputs received.
摘要:
The waved wood assembly can have a flexible support layer onto the face(s) of which one or more wood sheet layer(s) are adhered by an adhesive. The waved wood product can maintain its waved shape when freestanding. It can exhibit significant elasticity characteristics. It can have very accentuated waves, i.e. waves that span a greater thickness for a given number of waves per unit of dimension.
摘要:
A uridine diphospho-glucuronosyltransferase (UGTB217) is provided. Methods of producing the enzyme and using the enzyme to identify potential compounds which inhibit or alter the activity of the enzyme are described. In addition, methods of using antibodies to localize the protein, or using the gene sequence or portions thereof for probes or using the gene sequence to produce expression-disrupting sense or antisense DNA fragments thereof, or antisense RNA, are provided.