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    Open field system for magnetic surgery
    3.
    发明授权
    Open field system for magnetic surgery 有权
    开放磁场手术系统

    公开(公告)号：US06241671B1

    公开(公告)日：2001-06-05

    申请号：US09211723

    申请日：1998-12-14

    申请人： Rogers C. Ritter ,  Jeffrey M. Garibaldi ,  Charles Wolfersberger ,  Francis M. Creighton ,  Peter R. Werp ,  Bevil J. Hogg ,  Walter M. Blume

    发明人： Rogers C. Ritter ,  Jeffrey M. Garibaldi ,  Charles Wolfersberger ,  Francis M. Creighton ,  Peter R. Werp ,  Bevil J. Hogg ,  Walter M. Blume

    IPC分类号： A61B600

    CPC分类号： A61B34/73 ,  A61B6/0457 ,  A61B6/4441 ,  A61B34/70 ,  A61B2034/733

    摘要： A system of navigating a magnetic medical device within that part of a patient located within an operating region of the system, the system comprising magnets, and preferably electromagnets, arranged to provide a magnetic field sufficient to navigate the magnetic medical device within the operating region. There are preferably three magnetic coils arranged in mutually perpendicular planes such that their axes intersect in the operating region. The magnetic coils are sized and arranged so that a patient can easily access the operating region to allow virtually any portion of the patient to be positioned within the operating region. The openness of the magnetic system allows access to the operating region by a bi-planer imaging system.

    摘要翻译： 一种在位于系统的操作区域内的患者的该部分内导航磁性医疗装置的系统，所述系统包括磁体，优选地电磁体，其被设置为提供足以导航所述操作区域内的所述磁性医疗装置的磁场。 优选地，在相互垂直的平面中布置有三个磁性线圈，使得它们的轴线在操作区域相交。 磁性线圈的尺寸和布置使得患者可以容易地进入操作区域，以允许患者的几乎任何部分位于操作区域内。 磁性系统的开放性允许通过双平面成像系统进入操作区域。

    OPEN FIELD SYSTEM FOR MAGNETIC SURGERY
    4.
    发明申请
    OPEN FIELD SYSTEM FOR MAGNETIC SURGERY 审中-公开
    开放式磁场手术系统

    公开(公告)号：US20120330089A1

    公开(公告)日：2012-12-27

    申请号：US13441366

    申请日：2012-04-06

    申请人： Rogers C. Ritter ,  Jeffrey M. Garibaldi ,  Charles Wolfersberger ,  Francis M. Creighton ,  Peter R. Werp ,  Bevil J. Hogg ,  Walter M. Blume

    发明人： Rogers C. Ritter ,  Jeffrey M. Garibaldi ,  Charles Wolfersberger ,  Francis M. Creighton ,  Peter R. Werp ,  Bevil J. Hogg ,  Walter M. Blume

    IPC分类号： A61N2/02 ,  A61N2/10

    CPC分类号： A61B34/73 ,  A61B6/0457 ,  A61B6/4441 ,  A61B34/70 ,  A61B2034/733

    摘要： A system of navigating a magnetic medical device within that part of a patient located within an operating region of the system, the system comprising magnets, and preferably electromagnets, arranged to provide a magnetic field sufficient to navigate the magnetic medical device within the operating region. There are preferably three magnetic coils arranged in mutually perpendicular planes such that their axes intersect in the operating region. The magnetic coils are sized and arranged so that a patient can easily access the operating region to allow virtually any portion of the patient to be positioned within the operating region. The openness of the magnetic system allows access to the operating region by a bi-planer imaging system.

    摘要翻译： 一种在位于系统的操作区域内的患者的该部分内导航磁性医疗装置的系统，所述系统包括磁体，优选地电磁体，其被设置成提供足以在操作区域内导航磁性医疗装置的磁场。 优选地，在相互垂直的平面中布置有三个磁性线圈，使得它们的轴线在操作区域相交。 磁性线圈的尺寸和布置使得患者可以容易地进入操作区域，以允许患者的几乎任何部分位于操作区域内。 磁性系统的开放性允许通过双平面成像系统进入操作区域。

    DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS
    5.
    发明申请
    DEVICES FOR CONTROLLING MAGNETIC NANOPARTICLES TO TREAT FLUID OBSTRUCTIONS 有权
    用于控制磁性纳米颗粒以治疗流体阻塞的装置

    公开(公告)号：US20120310034A1

    公开(公告)日：2012-12-06

    申请号：US13505447

    申请日：2010-11-02

    申请人： Francis M. Creighton ,  Rogers C. Ritter

    发明人： Francis M. Creighton ,  Rogers C. Ritter

    IPC分类号： A61N2/10 ,  B82Y5/00

    CPC分类号： A61K41/00 ,  A61B17/22 ,  A61B17/22012 ,  A61B34/73 ,  A61B2017/00876 ,  A61B2017/22084 ,  A61B2017/22094 ,  A61B2034/733 ,  A61K9/0019 ,  A61K38/482 ,  A61K38/484 ,  A61K47/6941 ,  A61N2/004 ,  A61N2/02 ,  A61N2/06 ,  B82Y5/00 ,  C12Y304/21007 ,  C12Y304/21068 ,  H01F7/0273 ,  Y10S977/811 ,  Y10S977/905 ,  Y10S977/909

    摘要： The present invention relates to a system for the physical manipulation of free magnetic rotors in a circulatory system using a remotely placed magnetic field-generating stator. In one aspect, the invention relates to the control of magnetic particles in a fluid medium using permanent magnet-based or electromagnetic field-generating stator sources. Such a system can be useful for increasing the diffusion of therapeutic agents in a fluid medium, such as a human circulatory system, which can result in substantial clearance of fluid obstructions, such as vascular occlusions, in a circulatory system resulting in increased blood flow. Examples of vascular occlusions targeted by the system include, but are not limited to, atherosclerotic plaques, including fibrous caps, fatty buildup, coronary occlusions, arterial stenosis, restenosis, vein thrombi, arterial thrombi, cerebral thrombi, embolisms, hemorrhages, other blood clots, and very small vessels.

    摘要翻译： 本发明涉及一种用于使用远程放置的产生磁场的定子在循环系统中物理地操纵自由磁转子的系统。 一方面，本发明涉及使用基于永磁体或电磁场产生定子源的流体介质中的磁性颗粒的控制。 这种系统可用于增加治疗剂在诸如人类循环系统的流体培养基中的扩散，其可导致循环系统中的流体障碍（例如血管闭塞）的实质性清除，导致血流量增加。 系统靶向的血管闭塞的实例包括但不限于动脉粥样硬化斑块，包括纤维帽，脂肪积聚，冠状动脉闭塞，动脉狭窄，再狭窄，静脉血栓，动脉血栓，脑血栓，栓塞，出血，其他血块 ，和非常小的船只。

    MAGNETS WITH VARYING MAGNETIZATION DIRECTION AND METHOD OF MAKING SUCH MAGNETS
    6.
    发明申请
    MAGNETS WITH VARYING MAGNETIZATION DIRECTION AND METHOD OF MAKING SUCH MAGNETS 审中-公开
    具有变化的磁化方向的磁体和制造这种磁体的方法

    公开(公告)号：US20100163061A1

    公开(公告)日：2010-07-01

    申请号：US12568089

    申请日：2009-09-28

    申请人： Francis M. Creighton

    发明人： Francis M. Creighton

    IPC分类号： A61B19/00 ,  H01F7/02 ,  H01F1/00

    CPC分类号： H01F7/0273 ,  A61B17/00 ,  A61B34/73 ,  A61B2034/731 ,  A61N2/00 ,  H01F7/0278 ,  H01F7/0294 ,  H01F13/003 ,  H01F41/028 ,  Y10T29/4902

    摘要： A permanent magnet in which the magnetization direction varies with location to optimize or restrict a magnetic field property in a selected direction at a selected point. The magnetic field property may be, for example, the transverse magnetic field, axial magnetic field, axial gradient of the transverse magnetic field, transverse gradient of the transverse magnetic field, axis gradient of the axial magnetic field, transverse gradient of the axial magnetic field, the product of the transverse magnetic field and the transverse gradient of the transverse magnetic field, the product of the transverse magnetic field and the axial gradient of the transverse magnetic field, the product of the axial magnetic field and the transverse gradient of the axial magnetic field, or the product of the axial magnetic field and the axial gradient of the axial magnetic field. The magnet may be formed of one or more segments in which the magnetization direction varies smoothly and continuously, or the magnet may be formed of a plurality of segments in which the magnetization direction is constant. A method of making and using such magnets is also disclosed.

    摘要翻译： 一种永磁体，其中磁化方向随着位置而变化，以在选定的点优化或限制所选方向上的磁场特性。 磁场特性可以是例如横向磁场，轴向磁场，横向磁场的轴向梯度，横向磁场的横向梯度，轴向磁场的轴向梯度，轴向磁场的横向梯度 横向磁场和横向磁场横向梯度的乘积，横向磁场的乘积和横向磁场的轴向梯度，轴向磁场的乘积和轴向磁场的横向梯度 场或轴向磁场和轴向磁场的轴向梯度的乘积。 磁体可以由磁化方向平滑且连续地变化的一个或多个段形成，或者磁体可以由磁化方向恒定的多个段形成。 还公开了制造和使用这种磁体的方法。

    Magnets with varying magnetization direction and method of making such magnets
    7.
    发明授权
    Magnets with varying magnetization direction and method of making such magnets 有权
    具有变化的磁化方向的磁体和制造这种磁体的方法

    公开(公告)号：US06940379B2

    公开(公告)日：2005-09-06

    申请号：US10082715

    申请日：2002-02-25

    申请人： Francis M. Creighton

    发明人： Francis M. Creighton

    IPC分类号： A61B17/00 ,  H01F7/02

    CPC分类号： H01F7/0273 ,  A61B17/00 ,  A61B34/73 ,  A61B2034/731 ,  A61N2/00 ,  H01F7/0278 ,  H01F7/0294 ,  H01F13/003 ,  H01F41/028 ,  Y10T29/4902

    摘要： A permanent magnet in which the magnetization direction varies with location to optimize or restrict a magnetic field property in a selected direction at a selected point. The magnetic field property may be, for example, the transverse magnetic field, axial magnetic field, axial gradient of the transverse magnetic field, transverse gradient of the transverse magnetic field, axis gradient of the axial magnetic field, transverse gradient of the axial magnetic field, the product of the transverse magnetic field and the transverse gradient of the transverse magnetic field, the product of the transverse magnetic field and the axial gradient of the transverse magnetic field, the product of the axial magnetic field and the transverse gradient of the axial magnetic field, or the product of the axial magnetic field and the axial gradient of the axial magnetic field. The magnet may be formed of one or more segments in which the magnetization direction varies smoothly and continuously, or the magnet may be formed of a plurality of segments in which the magnetization direction is constant. A method of making and using such magnets is also disclosed.

    摘要翻译： 一种永磁体，其中磁化方向随着位置而变化，以在选定的点优化或限制所选方向上的磁场特性。 磁场特性可以是例如横向磁场，轴向磁场，横向磁场的轴向梯度，横向磁场的横向梯度，轴向磁场的轴向梯度，轴向磁场的横向梯度 横向磁场和横向磁场横向梯度的乘积，横向磁场的乘积和横向磁场的轴向梯度，轴向磁场的乘积和轴向磁场的横向梯度 场或轴向磁场和轴向磁场的轴向梯度的乘积。 磁体可以由磁化方向平滑且连续地变化的一个或多个段形成，或者磁体可以由磁化方向恒定的多个段形成。 还公开了制造和使用这种磁体的方法。