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11 条记录 (耗时 0.062 秒)

    Method for detecting pathogenic organisms in fecal and salivary specimens and in biopsy material
    1.
    发明申请
    Method for detecting pathogenic organisms in fecal and salivary specimens and in biopsy material 审中-公开
    检测粪便和唾液样本以及活检材料中致病生物的方法

    公开(公告)号：US20070087395A1

    公开(公告)日：2007-04-19

    申请号：US11542293

    申请日：2006-10-03

    申请人： Franz Armbruster ,  Katarina Crevar ,  Jana Ruppert

    发明人： Franz Armbruster ,  Katarina Crevar ,  Jana Ruppert

    IPC分类号： G01N33/554 ,  G01N33/569

    CPC分类号： G01N33/56922 ,  G01N33/54306 ,  G01N33/56911 ,  G01N33/6854

    摘要： The invention relates to a method for detecting pathogenic organisms, in particular Helicobacter pylori and H. heilmanii, in fecal, salivary and secretory samples by means of a double-antibody sandwich assay. The inventive method is characterized by dissolving or dispersing the sample having the pathogen antigen in a buffer solution and contacting the buffer solution with a solid phase to which at least two primary antibodies are bound, one of which specifically binds to the pathogenic antigen and the other to human immunoglobulin A; washing the solid phase of non-specifically bound proteins and contacting the solid phase with a secondary antibody which specifically binds to pathogenic antigen, and determining the quantity of specifically bound secondary antibodies.

    摘要翻译： 本发明涉及一种通过双重抗体夹心测定法在粪便，唾液和分泌样品中检测病原生物体，特别是幽门螺杆菌和黑曲霉的方法。 本发明的方法的特征在于将具有病原体抗原的样品溶解或分散在缓冲溶液中，并将缓冲溶液与至少两种一抗结合的固相接触，其中一种特异性结合致病抗原，另一种 对人免疫球蛋白A; 洗涤非特异性结合的蛋白质的固相并使固相与特异性结合病原性抗原的第二抗体接触，并测定特异性结合的二级抗体的量。

    Method and Kit for the Microbiological Determination of Vitamins in Substance Mixtures
    2.
    发明申请
    Method and Kit for the Microbiological Determination of Vitamins in Substance Mixtures 失效
    用于物质混合物中维生素微生物测定的方法和试剂盒

    公开(公告)号：US20080044846A1

    公开(公告)日：2008-02-21

    申请号：US11658804

    申请日：2005-08-01

    申请人： Wolfgang Weber ,  Franz Armbruster

    发明人： Wolfgang Weber ,  Franz Armbruster

    IPC分类号： C12Q1/02 ,  C12M1/34

    CPC分类号： C12Q1/025

    摘要： Method for the quantitative determination of vitamins, amino acids, or other substances necessary for life, in a substance mixture, whereby in the culture container, the cavities of a microtitration plate, in each case a predetermined number of vital cells of a suitable microorganism are prepared in a permanent manner. For this purpose, the cells are shock frozen at −80° C. and then freeze dried in a freezing solution containing 200 to 500 mM trehalose/sucrose. The freezing solution is preferably the test medium. The culture containers are preferably the wells of a microtitration plate.

    摘要翻译： 用于在物质混合物中定量测定维生素，氨基酸或其他生命所需物质的方法，由此在培养容器中，微量滴定板的空腔在每种情况下都是预定数量的合适微生物的活细胞 以永久的方式准备。 为此目的，将细胞在-80℃下休克冷冻，然后在含有200至500mM海藻糖/蔗糖的冷冻溶液中冷冻干燥。 冷冻溶液优选为测试介质。 培养容器优选为微量滴定板的孔。

    Functional vitamin D derivatives and method of determining 25-hydroxy- and 1alpha, 25-dihydroxy vitamin D
    3.
    发明申请
    Functional vitamin D derivatives and method of determining 25-hydroxy- and 1alpha, 25-dihydroxy vitamin D 有权
    功能性维生素D衍生物和测定25-羟基和1α，25-二羟维生素D的方法

    公开(公告)号：US20050014211A1

    公开(公告)日：2005-01-20

    申请号：US10790746

    申请日：2004-03-03

    申请人： Franz Armbruster ,  Wolfgang Voelter ,  Jens Tampe ,  Christian Birkmayer

    发明人： Franz Armbruster ,  Wolfgang Voelter ,  Jens Tampe ,  Christian Birkmayer

    IPC分类号： G01N33/82 ,  G01N33/53 ,  C07C401/00 ,  G01N33/537 ,  G01N33/543

    CPC分类号： G01N33/82 ,  Y10T436/13

    摘要： The preparation of vitamin D compounds of formula (I) with a label attached to a spacer group in the 3 position is disclosed. In the above formula (I), O represents the oxygen atom of an ether group; Y represents hydrogen or hydroxy; A represents a label such as biotin, digoxigenin, or another vitamin D group; R represents a substitured hydrocarbon side-group of vitamin D or a vitamin D metabolite. Also disclosed is a method of measuring 25-hydroxy vitamin D metabolite and a 1α,25-dihydroxy vitamin D metabolite in a sample.

    摘要翻译： 公开了具有连接到3位上的间隔基的标记的式（I）的维生素D化合物的制备。 在上述式（I）中，O表示醚基的氧原子; Y表示氢或羟基; A代表生物素，地高辛或其他维生素D组的标签; R代表维生素D或维生素D代谢物的替代碳氢化合物侧基。 还公开了一种在样品中测量25-羟基维生素D代谢物和1α，25-二羟基维生素D代谢物的方法。

    Current collecting unit
    4.
    发明授权
    Current collecting unit 失效
    电流采集单元

    公开(公告)号：US4943687A

    公开(公告)日：1990-07-24

    申请号：US289199

    申请日：1988-12-23

    申请人： Franz Armbruster ,  Carsten Bauer ,  Friedhelm Meyer

    发明人： Franz Armbruster ,  Carsten Bauer ,  Friedhelm Meyer

    IPC分类号： H01R4/02

    CPC分类号： H01R4/029 ,  Y10T403/478

    摘要： A current collecting unit comprises a current collecting rail having a longitudinal axis and provided with a sleeve, and a connecting member mounted in the sleeve having one curved portion located above the longitudinal axis and another curved portion located below the longitudinal axis and both forming electrode supports.

    摘要翻译： 电流收集单元包括具有纵向轴线并设置有套筒的集电导轨，以及安装在套筒中的连接构件，其具有位于纵向轴线上方的一个弯曲部分和位于纵向轴线下方的另一个弯曲部分，并且两者形成电极支撑件 。

    Method of resistance welding wires to a massive workpiece
    8.
    发明授权
    Method of resistance welding wires to a massive workpiece 失效
    电焊丝与大块工件的焊接方法

    公开(公告)号：US4203020A

    公开(公告)日：1980-05-13

    申请号：US908931

    申请日：1978-05-24

    申请人： Franz Armbruster ,  Albano Paoli ,  Gerd Bassler ,  Hans-Peter Sitka ,  Gunter Schmidt

    发明人： Franz Armbruster ,  Albano Paoli ,  Gerd Bassler ,  Hans-Peter Sitka ,  Gunter Schmidt

    IPC分类号： B23K11/14 ,  B23K11/20

    CPC分类号： B23K11/14 ,  B23K11/20

    摘要： A method for producing strong resistance-welded joints between wires and massive workpieces, especially welded joints between nickel-plated copper wires and steel workpieces. The melting of the nickel coating is insured by producing locally high temperatures and pressures, due to the special configuration of the surface of the workpiece. The work surface is provided with bulges or protrusions which cause a concentration of electrical current and electrode pressure.

    摘要翻译： 一种在电线和大块工件之间生产强电阻焊接头的方法，特别是镀镍铜线和钢工件之间的焊接接头。 由于工件表面的特殊配置，镍涂层的熔化通过产生局部高温和高压来保证。 工作面设置有引起电流和电极压力集中的凸起或凸起。

    Method for determining effective parathormone activity in a sample
    10.
    发明申请
    Method for determining effective parathormone activity in a sample 有权
    确定样品中有效的parathormone活性的方法

    公开(公告)号：US20060211054A1

    公开(公告)日：2006-09-21

    申请号：US10473975

    申请日：2002-04-03

    申请人： Franz Armbruster ,  Heinz-Juergen Roth ,  Heinrich Schmidt-Gayk

    发明人： Franz Armbruster ,  Heinz-Juergen Roth ,  Heinrich Schmidt-Gayk

    IPC分类号： G01N33/53 ,  C07K16/46 ,  C07K16/26

    CPC分类号： G01N33/74 ,  G01N2333/635

    摘要： Method for determining the active parathyroid hormone content in a sample, wherein the component of parathyroid hormone polypeptide chains which are oxidized at one or more sites near the PTH receptor binding structure having the amino acids 15 to 22 are specifically excluded from the content determination. Oxidation of the parathyroid hormone occurs in particular in dialysis patients, their blood plasma being exposed to an oxidation stress in the dialysis. The invention is based on the use of antibodies which bind specific conformation epitopes of the oxidised or reduced parathyroid hormone and its fragments. Further, there is provided a test system for the quantitative determination of parathyroid hormone and active fragments hereof in a sample.

    摘要翻译： 用于测定样品中活性甲状旁腺激素含量的方法，其中在具有氨基酸15至22的PTH受体结合结构附近的一个或多个位点处氧化的甲状旁腺激素多肽链的组分被特异性排除在内容确定之外。 甲状旁腺激素的氧化特别是在透析患者中​​发生，其血浆在透析中暴露于氧化应激。 本发明基于使用结合氧化或还原的甲状旁腺激素及其片段的特异性构象表位的抗体。 此外，提供了用于在样品中定量测定甲状旁腺激素及其活性片段的测试系统。