-
公开(公告)号：US07531507B2
公开(公告)日：2009-05-12
申请号：US11267063
申请日：2005-11-04
申请人： Franz Von Nussbaum , Nina Brunner , Rainer Endermann , Chantal Fuerstner , Elke Hartmann , Holger Paulsen , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruening
发明人： Franz Von Nussbaum , Nina Brunner , Rainer Endermann , Chantal Fuerstner , Elke Hartmann , Holger Paulsen , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruening
CPC分类号： C07K7/06
摘要： The invention relates to nonadepsipeptides and processes for their preparation, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
摘要翻译： 本发明涉及非肽缩肽及其制备方法，以及它们用于生产药物用于治疗和/或预防疾病，特别是细菌感染性疾病的用途。
-
公开(公告)号：US20060264358A1
公开(公告)日：2006-11-23
申请号：US11267063
申请日：2005-11-04
申请人： Franz Nussbaum , Nina Brunner , Rainer Endermann , Chantal Furstner , Elke Hartmann , Holger Paulsen , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruning
发明人： Franz Nussbaum , Nina Brunner , Rainer Endermann , Chantal Furstner , Elke Hartmann , Holger Paulsen , Jacques Ragot , Guido Schiffer , Joachim Schuhmacher , Niels Svenstrup , Joachim Telser , Sonja Anlauf , Michael-Alexander Bruning
CPC分类号： C07K7/06
摘要： The invention relates to nonadepsipeptides and processes for their preparation, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial infectious diseases.
摘要翻译： 本发明涉及非肽缩肽及其制备方法，以及它们用于生产药物用于治疗和/或预防疾病，特别是细菌感染性疾病的用途。
-
公开(公告)号：US07405201B2
公开(公告)日：2008-07-29
申请号：US10490192
申请日：2002-09-06
申请人： Berthold Hinzen , Heike Brötz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
发明人： Berthold Hinzen , Heike Brötz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
摘要： The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
摘要翻译： 本发明涉及通式（I）的化合物，其制备方法，包含它们的药物组合物及其在治疗人或动物疾病中的用途。
-
公开(公告)号：US20050107288A1
公开(公告)日：2005-05-19
申请号：US10490192
申请日：2002-09-06
申请人： Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
发明人： Berthold Hinzen , Heike Brotz-Oesterhelt , Rainer Endermann , Kerstin Henninger , Holger Paulsen , Siegfried Raddatz , Thomas Lampe , Veronika Hellwig , Andreas Schumacher
摘要： The present invention relates to compounds of the general formula (I), processes for their preparation, pharmaceutical compositions comprising them, and their use in the treatment of diseases in humans or animals.
摘要翻译： 本发明涉及通式（I）的化合物，其制备方法，包含它们的药物组合物及其在治疗人或动物疾病中的用途。
-
公开(公告)号：US07074780B2
公开(公告)日：2006-07-11
申请号：US10715283
申请日：2003-11-17
申请人： Erwin Bischoff , Thomas Krahn , Stephan-Nicholas Müller , Holger Paulsen , Joachim Schuhmacher , Henning Steinhagen , Wolfgang Thielemann
发明人： Erwin Bischoff , Thomas Krahn , Stephan-Nicholas Müller , Holger Paulsen , Joachim Schuhmacher , Henning Steinhagen , Wolfgang Thielemann
IPC分类号： A61K31/33 , A61K31/38 , A61K31/16 , C07D331/02 , C07D333/02
CPC分类号： C07D213/40 , C07C233/63 , C07C235/12 , C07C235/40 , C07C237/24 , C07C271/16 , C07C271/20 , C07C271/22 , C07C271/24 , C07C275/26 , C07C275/42 , C07C317/50 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2603/74 , C07D213/56 , C07D213/75 , C07D213/81 , C07D231/12 , C07D233/56 , C07D249/08 , C07D295/205 , C07D295/215
摘要： The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in medicaments, in particular for the prevention and/or treatment of cardiovascular disorders.
-
公开(公告)号：US06649616B2
公开(公告)日：2003-11-18
申请号：US09943325
申请日：2001-08-30
申请人： Erwin Bischoff , Thomas Krahn , Stephan-Nicholas Müller , Holger Paulsen , Joachim Schuhmacher , Henning Steinhagen , Wolfgang Thielemann
发明人： Erwin Bischoff , Thomas Krahn , Stephan-Nicholas Müller , Holger Paulsen , Joachim Schuhmacher , Henning Steinhagen , Wolfgang Thielemann
IPC分类号： A61K3133
CPC分类号： C07D213/40 , C07C233/63 , C07C235/12 , C07C235/40 , C07C237/24 , C07C271/16 , C07C271/20 , C07C271/22 , C07C271/24 , C07C275/26 , C07C275/42 , C07C317/50 , C07C2601/02 , C07C2601/08 , C07C2601/14 , C07C2601/18 , C07C2603/74 , C07D213/56 , C07D213/75 , C07D213/81 , C07D231/12 , C07D233/56 , C07D249/08 , C07D295/205 , C07D295/215
摘要： The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in medicaments, in particular for the prevention and/or treatment of cardiovascular disorders.
摘要翻译： 本发明涉及式（I）的取代的苯基环己烷甲酰胺，用于其制备方法及其在药物中的用途，特别是用于预防和/或治疗心血管疾病。
-
公开(公告)号：US06207671B1
公开(公告)日：2001-03-27
申请号：US09521648
申请日：2000-03-08
申请人： Gunter Schmidt , Arndt Brandes , Rolf Angerbauer , Michael Lögers , Matthias Müller-Gliemann , Carsten Schmeck , Klaus-Dieter Bremm , Hilmar Bischoff , Delf Schmidt , Joachim Schuhmacher , Henry Giera , Holger Paulsen , Paul Naab , Michael Conrad , Jürgen Stoltefuss
发明人： Gunter Schmidt , Arndt Brandes , Rolf Angerbauer , Michael Lögers , Matthias Müller-Gliemann , Carsten Schmeck , Klaus-Dieter Bremm , Hilmar Bischoff , Delf Schmidt , Joachim Schuhmacher , Henry Giera , Holger Paulsen , Paul Naab , Michael Conrad , Jürgen Stoltefuss
IPC分类号： A61K31438
CPC分类号： C07F7/1804
摘要： The cycloalkano-pyridines are prepared by reacting corresponding cycloalkano-pyridine-aldehydes with suitable organometallic compounds or Wittig or Grignard reagents or reacting compounds of the cycloalkano-pyridine alcohols type with suitable bromine compounds, and optionally varying the functional groups accordingly. The cycloalkanopyridines are suitable as active compounds in medicaments, in particular in medicaments for the treatment of hypertipoproteinaemia and arteriosclerosis.
摘要翻译： 通过使相应的环烷基 - 吡啶 - 醛与合适的有机金属化合物或Wittig或格氏试剂反应或使环烷基 - 吡啶醇类型的化合物与合适的溴化合物反应，并且任选地相应地改变官能团，制备环烷基 - 吡啶。 环烷基吡啶类药物适合作为药物中的活性化合物，特别是用于治疗高血脂蛋白血症和动脉硬化的药物。
-
8.发明授权Substituted phenylcyclohexane carboxylic acid amides and their use as adenosine uptake inhibitors 失效取代的苯基环己烷羧酸酰胺及其作为腺苷摄取抑制剂的用途公开(公告)号：US06984642B1
公开(公告)日：2006-01-10
申请号：US09980242
申请日：2000-05-16
申请人： Erwin Bischoff , Stephan Lensky , Stephan-Nicholas Müller , Holger Paulsen , Jörg Keldenich , Thomas Krahn , Joachim Schuhmacher , Jan Jänichen , Wolfgang Thielemann , Henning Steinhagen
发明人： Erwin Bischoff , Stephan Lensky , Stephan-Nicholas Müller , Holger Paulsen , Jörg Keldenich , Thomas Krahn , Joachim Schuhmacher , Jan Jänichen , Wolfgang Thielemann , Henning Steinhagen
IPC分类号： A61K31/496 , C07D403/04
CPC分类号： C07D235/24 , A61K31/4184 , A61K31/437 , C07D235/12 , C07D235/14 , C07D235/30 , C07D471/04
摘要： The present invention relates to substituted phenylcyclohexanecaboxamides of the formula (I), to processes for their preparation and to their use in medicaments, in particular for treating cardiovascular disorders.
摘要翻译： 本发明涉及式（I）的取代的苯基环己烷甲酰胺，其制备方法及其在药物中的用途，特别是用于治疗心血管疾病。
-
9.发明申请Substituted piperazine cyclohexane carboxilic acid amides and the use thereof 审中-公开取代的哌嗪环己烷羧酸酰胺及其用途公开(公告)号：US20050054637A1
公开(公告)日：2005-03-10
申请号：US10492337
申请日：2002-10-01
申请人： Erwin Bischoff , Thomas Krahn , Holger Paulsen , Joachim Schuhmacher , Henning Steinhagen , Wolfgang Thielemann
发明人： Erwin Bischoff , Thomas Krahn , Holger Paulsen , Joachim Schuhmacher , Henning Steinhagen , Wolfgang Thielemann
IPC分类号： C07D295/14 , A61K31/495 , A61K31/496 , A61K31/501 , A61P7/02 , A61P7/10 , A61P9/08 , A61P9/10 , A61P19/08 , A61P25/04 , A61P25/08 , A61P25/18 , A61P25/20 , A61P35/00 , A61P43/00 , C07D207/34 , C07D207/40 , C07D207/416 , C07D209/08 , C07D209/42 , C07D213/38 , C07D213/71 , C07D213/81 , C07D213/82 , C07D215/12 , C07D215/50 , C07D215/54 , C07D217/26 , C07D231/12 , C07D231/14 , C07D231/56 , C07D233/84 , C07D233/90 , C07D235/04 , C07D237/24 , C07D261/14 , C07D275/04 , C07D295/155 , C07D295/18 , C07D295/192 , C07D295/20 , C07D295/215 , C07D295/22 , C07D295/26 , C07D307/68 , C07D317/58 , C07D317/68 , C07D333/34 , C07D333/38 , C07D417/02 , C07D413/02 , C07D43/02
CPC分类号： C07D207/416 , C07D213/71 , C07D231/56 , C07D295/155 , C07D295/192 , C07D295/215 , C07D295/26 , C07D333/38
摘要： The present invention relates to substituted piperazinecyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in pharmaceuticals, in particular for the prophylaxis and/or treatment of cardiovascular disorders.
摘要翻译： 本发明涉及式（I）的取代的哌嗪环己烷甲酰胺，其制备方法及其在药物中的用途，特别是用于预防和/或治疗心血管疾病。
-
10.发明授权Substituted phenylcyclohexane carboxylic acid amides that have an adenosine uptake inhibiting effect 失效具有腺苷摄取抑制作用的取代的苯基环己烷羧酸酰胺公开(公告)号：US06716849B1
公开(公告)日：2004-04-06
申请号：US09980243
申请日：2001-11-29
申请人： Wolf-Dietrich Freund , Stephan Lensky , Stephan Nicholas Müller , Holger Paulsen , Jörg Keldenich , Ervin Horváth , Joachim Schuhmacher
发明人： Wolf-Dietrich Freund , Stephan Lensky , Stephan Nicholas Müller , Holger Paulsen , Jörg Keldenich , Ervin Horváth , Joachim Schuhmacher
IPC分类号： A61K31496
CPC分类号： C07D471/04 , C07D235/14 , C07D235/18 , C07D235/30
摘要： The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) having adenosine-uptake-inhibiting action, to a process for their preparation and to their use in medicaments, in particular for treating ischaemic brain disorders.
摘要翻译： 本发明涉及具有腺苷摄取抑制作用的式（I）的取代苯基环己烷甲酰胺，其制备方法及其在药物中的用途，特别是用于治疗缺血性脑病。
-
-
-
-
-
-
-
-
-
搜索结果
25 条记录 (耗时 0.055 秒)
