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公开(公告)号：US10450540B2
公开(公告)日：2019-10-22
申请号：US15306691
申请日：2015-04-27
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Klaus Gebauer , Andreas Castan , Camilla Estmer-Nilsson , Thomas Falkman , Anders Wilen , Michael Miller , Ralph Stankowski
Abstract: The invention discloses a flexible bag assembly for cultivation of cells, comprising one or more bags forming a plurality of cultivation compartments, wherein a drain port in at least a first cultivation compartment is adapted to be fluidically connected with a second cultivation compartment upon opening of a valve means. It also discloses a bioreactor with the bag assembly mounted on a rocking tray and a method of cultivating cells in the assembly.
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公开(公告)号：US20170044477A1
公开(公告)日：2017-02-16
申请号：US15306691
申请日：2015-04-27
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Klaus Gebauer , Andreas Castan , Camilla Estmer-Nilsson , Thomas Falkman , Anders Wilen , Michael Miller , Ralph Stankowski
CPC classification number: C12M23/14 , C12M23/26 , C12M23/34 , C12M23/58 , C12M27/16 , C12M41/24 , C12Q3/00
Abstract: The invention discloses a flexible bag assembly for cultivation of cells, comprising one or more bags forming a plurality of cultivation compartments, wherein a drain port in at least a first cultivation compartment is adapted to be fluidically connected with a second cultivation compartment upon opening of a valve means. It also discloses a bioreactor with the bag assembly mounted on a rocking tray and a method of cultivating cells in the assembly.
Abstract translation: 本发明公开了一种用于培养细胞的柔性袋组件，包括形成多个培养隔室的一个或多个袋，其中至少第一栽培室中的排出口适于在打开第二培养室时与第二培养室流体连接 阀门装置。 它还公开了一种生物反应器，其中袋组件安装在摆动托盘上，以及在组件中培养细胞的方法。
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Patent Agency Ranking
公开(公告)号：US20150367992A1
公开(公告)日：2015-12-24
申请号：US14410595
申请日：2013-06-20
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Shujian YI , Rolf Hjorth , David Ronnholm , Thomas Falkman
CPC classification number: B65D33/02 , B29C65/02 , B29C65/10 , B29C65/48 , B29C65/4815 , B29C65/482 , B29C65/4835 , B29C65/4845 , B29C65/72 , B29C66/12441 , B29C66/47421 , B29C66/542 , B29C66/71 , B29C66/7234 , B29C66/7315 , B29C66/7392 , B29C66/73921 , B29K2101/12 , B29K2995/0082 , B29L2031/712 , B29L2031/7128 , C12M23/14 , B29K2077/00 , B29K2023/04 , B29K2023/10 , B29K2023/06 , B29K2023/086 , B29K2023/12 , B29K2031/00 , B29K2067/00
Abstract: A container comprising a first material and a second material, the first material being a flexible material and the second material being a rigid or semi-rigid material and at least partially defining an interior compartment for keeping a fluid inside the container characterized in that the flexible material and/or the semi-rigid or rigid material have thermoplastic properties and wherein the flexible material and the semi-rigid or rigid material are joined together by means of a seal or joint which comprises a heat seal and an adhesive seal
Abstract translation: 一种包含第一材料和第二材料的容器，所述第一材料是柔性材料，所述第二材料是刚性或半刚性材料，并且至少部分地限定用于将流体保持在所述容器内的内部隔室，其特征在于，所述柔性 材料和/或半刚性或刚性材料具有热塑性能，并且其中柔性材料和半刚性或刚性材料通过密封或接头连接在一起，所述密封或接头包括热封和粘合密封
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公开(公告)号：US20180243679A1
公开(公告)日：2018-08-30
申请号：US15753349
申请日：2016-08-23
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor： Eric Faldt , Thomas Falkman , Patric Fricking , Patrick Jonsson , Tomas Agren
CPC classification number: B01D46/4263 , B01D5/0021 , B01D5/0069 , B01D5/0072 , B01D5/0075 , B01D53/002 , B01D53/265 , C12M23/14 , C12M23/26 , C12M23/48 , C12M27/00 , C12M29/06 , C12M29/20
Abstract: The invention discloses a condenser for a bioreactor exhaust, comprising: an inlet (1) adapted to be fluidically connected to a bioreactor exhaust port (2), a cooling chamber (3; 103) fluidically connected to the inlet and via a filter device (4) to an outlet (5), a cooling conduit (6; 106) in contact with the cooling chamber, a heating conduit (7) in contact with the filter device and a vortex tube (8) arranged to convey a cold gas stream through the cooling conduit and to convey a hot gas stream through the heating conduit.
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公开(公告)号：US20170313967A1
公开(公告)日：2017-11-02
申请号：US15653501
申请日：2017-07-18
Applicant: GE HEALTHCARE BIO-SCIENCES AB
Inventor： Andreas Andersson , Johan L. Carlsson , Christian Elnegard , Henrik K. Eriksson , Thomas Falkman , Patric Fricking , Linnea Pauler , Claes Petterson
CPC classification number: C12M27/16 , B01F11/0017 , B01F15/0085 , C12M23/14 , C12M23/50
Abstract: The present invention relates to a bioreactor including at least one reactor vessel in form of a plastic bag, a tray (4) for holding said at least one bag, a rocking device for limited rocking motions of the tray (4) around a rocking axis (2). According to the invention the bioreactor comprises a device (6,7,8,9) for enabling swinging of the tray (4) around a second axis (7) parallel to and distanced from the rocking axis (2).
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公开(公告)号：US20200087605A1
公开(公告)日：2020-03-19
申请号：US16586272
申请日：2019-09-27
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Klaus Gebauer , Andreas Castan , Camilla Estmer-Nilsson , Thomas Falkman , Anders Wilen , Michael Miller , Ralph Stankowski
Abstract: The invention discloses a flexible bag assembly for cultivation of cells, comprising one or more bags forming a plurality of cultivation compartments, wherein a drain port in at least a first cultivation compartment is adapted to be fluidically connected with a second cultivation compartment upon opening of a valve means. It also discloses a bioreactor with the bag assembly mounted on a rocking tray and a method of cultivating cells in the assembly.
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公开(公告)号：US09550609B2
公开(公告)日：2017-01-24
申请号：US14410595
申请日：2013-06-20
Applicant: GE Healthcare Bio-Sciences AB
Inventor： Shujian Yi , Rolf Hjorth , David Ronnholm , Thomas Falkman
IPC: B65D33/02 , B29C65/48 , B29C65/72 , B29C65/02 , C12M1/00 , B29C65/10 , B29C65/00 , B29L31/00 , B29K101/12
CPC classification number: B65D33/02 , B29C65/02 , B29C65/10 , B29C65/48 , B29C65/4815 , B29C65/482 , B29C65/4835 , B29C65/4845 , B29C65/72 , B29C66/12441 , B29C66/47421 , B29C66/542 , B29C66/71 , B29C66/7234 , B29C66/7315 , B29C66/7392 , B29C66/73921 , B29K2101/12 , B29K2995/0082 , B29L2031/712 , B29L2031/7128 , C12M23/14 , B29K2077/00 , B29K2023/04 , B29K2023/10 , B29K2023/06 , B29K2023/086 , B29K2023/12 , B29K2031/00 , B29K2067/00
Abstract: A container comprising a first material and a second material, the first material being a flexible material and the second material being a rigid or semi-rigid material and at least partially defining an interior compartment for keeping a fluid inside the container characterized in that the flexible material and/or the semi-rigid or rigid material have thermoplastic properties and wherein the flexible material and the semi-rigid or rigid material are joined together by a seal or joint which comprises a heat seal and an adhesive seal.
Abstract translation: 一种包含第一材料和第二材料的容器，所述第一材料是柔性材料，所述第二材料是刚性或半刚性材料，并且至少部分地限定用于将流体保持在所述容器内的内部隔室，其特征在于，所述柔性 材料和/或半刚性或刚性材料具有热塑性质，并且其中柔性材料和半刚性或刚性材料通过包括热密封和粘合密封的密封或接头连接在一起。
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