-
公开(公告)号：US20170151545A1
公开(公告)日：2017-06-01
申请号：US15102209
申请日：2014-11-26
CPC分类号： B01J19/0046 , B01J2219/00529 , B01J2219/00596 , B01J2219/00722 , C12Q1/68 , C12Q1/6874 , C12Q2563/185
摘要： A data storage medium is disclosed comprising a solid support matrix including an optional stabilising reagent or reagents in a dry form, for use as a support for artificially synthesised oligonucleotide sequences encoded with data. Preferably the matrix is fibrous (for example cellulose, or glass, fibres) formed into a support of sufficient strength to hold the oligonucleotide sequences. The stabilising reagents are preferably a combination of a weak base, and a chelating agent, optionally, uric acid or a urate salt, and optionally an anionic surfactant.
-
公开(公告)号：US20200378958A1
公开(公告)日：2020-12-03
申请号：US16607233
申请日：2018-04-11
发明人： Jeffrey Kenneth Horton , Peter James Tatnell , Alan Pierce , Alexander Schenk , Rebecca Ngaire Fullerton
IPC分类号： G01N33/538 , C07K1/34 , C07K1/36 , G01N33/543 , B01D69/12 , B01D69/14
摘要： The present invention relates to a device and method for sample preparation and collection. More closely the invention relates to a device to isolate DNA, RNA and proteins or other biomolecules in one single step from the same undivided sample
-
公开(公告)号：US20170205406A1
公开(公告)日：2017-07-20
申请号：US15477816
申请日：2017-04-03
发明人： Jeffrey Kenneth Horton , Peter James Tatnell , Samantha Jane Ogden , Michael John Smith , Leonard Goren , Steven Pepe , Samit Langar , Vincent Hok Liu Francis Pizzi , Craig Robinson
IPC分类号： G01N33/558 , B01L3/00 , G01N1/28
CPC分类号： G01N33/558 , B01L3/5055 , B01L2300/022 , B01L2300/12 , G01N1/28
摘要： A biometric device, comprising a solid support suitable for receiving biological material and for dry storing that material at room temperature the device further comprising a circuit including means for two way radio frequency communication and including writable data storage. A processing method for such biometric devices, the method including the steps of: a) identifying said device by means of RF communication; b) extracting at least a portion of the biological material from the solid support of the identified device; c) analysing the extracted biological material to obtain biometric data indicative of the biological material; and d) writing said biometric data to the data storage of the biometric device.
-
4.发明申请公开(公告)号：US20170260566A1
公开(公告)日：2017-09-14
申请号：US15529597
申请日：2015-12-08
IPC分类号： C12Q1/68 , G01N33/543
CPC分类号： C12Q1/6804 , C12Q1/6851 , C12Q1/686 , C12Q2525/205 , G01N33/54306 , G01N2458/10 , C12Q2563/131 , C12Q2531/113 , C12Q2565/50
摘要： Embodiments of the invention provides a method for detection of at least one analyte derived from a sample, comprising the steps of: a) depositing the sample on a surface of a solid support; b) transferring at least a portion of the solid support to a receptacle suitable for performing a specific binding assay for one or more analytes of interest; c) optionally washing the portion; d) adding a single specific binding partner for each analyte of interest to the receptacle, the binding partner being labelled with an oligonucleotide sequence; e) mixing the portion with nucleic acid amplification reagents; f) amplifying the oligonucleotide sequence; and g) detecting amplified nucleic acid. The invention also provides a kit for use with the method for detection of at least one analyte derived from a sample.
-
5.发明授权公开(公告)号：US11008604B2
公开(公告)日：2021-05-18
申请号：US15529597
申请日：2015-12-08
IPC分类号： C12Q1/68 , G01N33/50 , G01N33/53 , C12Q1/6804 , G01N33/543 , C12Q1/686 , C12Q1/6851
摘要： Embodiments of the invention provides a method for detection of at least one analyte derived from a sample, comprising the steps of: a) depositing the sample on a surface of a solid support; b) transferring at least a portion of the solid support to a receptacle suitable for performing a specific binding assay for one or more analytes of interest; c) optionally washing the portion; d) adding a single specific binding partner for each analyte of interest to the receptacle, the binding partner being labelled with an oligonucleotide sequence; e) mixing the portion with nucleic acid amplification reagents; f) amplifying the oligonucleotide sequence; and g) detecting amplified nucleic acid. The invention also provides a kit for use with the method for detection of at least one analyte derived from a sample.
-
6.发明申请公开(公告)号：US20180031575A1
公开(公告)日：2018-02-01
申请号：US15525715
申请日：2015-10-14
摘要： Embodiments of the invention provides a method for detecting one or more biomarkers derived from a body fluid, comprising performing one or more assays for the biomarkers from a sample of the body fluid, whereby the sample is previously preserved on a solid support; wherein a change in the biomarkers provides an indication of a biological event in the brain. The invention also provides related methods for identifying a person as being at risk of dementia or Alzheimer's disease, monitoring a person for the onset or progression of dementia or Alzheimer's disease, evaluating the effectiveness of a potential pharmaceutical agent.
-
公开(公告)号：US20170131188A1
公开(公告)日：2017-05-11
申请号：US15318297
申请日：2015-06-23
IPC分类号： G01N1/28 , B01L3/00 , G01N33/574 , C12Q1/68
CPC分类号： G01N1/2813 , B01L3/508 , B01L2200/16 , C12Q1/6806 , C12Q1/6841 , C12Q1/686 , G01N33/574 , G01N2001/282 , C12Q2527/125 , C12Q2565/513 , C12Q2565/518
摘要： Disclosed is a method for capturing the spatial molecular profiling of a biological mass formed from biological material, comprising the steps of: a) providing a transected biological mass, for example a tumour, the transection exposing at least a portion of the mass; b) providing a solid support of an area at least equalling the area of said portion of the mass; c) transferring biological material from the portion of the mass to the support to provide on the support a two dimensional imprint of the biological material present at the portion of the mass; and d) performing a biological assay of the transferred biological material from different predetermined locations of the imprint in order to determine the spatial molecular profile of the portion of the mass.
-
公开(公告)号：US09618428B2
公开(公告)日：2017-04-11
申请号：US13766954
申请日：2013-02-14
发明人： Jeffrey Kenneth Horton , Peter James Tatnell , Samantha Jane Ogden , Michael John Smith , Leonard J. Goren , Steven Pepe , Samit Langar , Vincent Francis Pizzi , Craig Robinson
IPC分类号： G06F19/00 , G01N1/28 , G01N33/558 , B01L3/00 , G01N31/00
CPC分类号： G01N33/558 , B01L3/5055 , B01L2300/022 , B01L2300/12 , G01N1/28
摘要： There is disclosed a biometric device (10), comprising a solid support (14) suitable for receiving biological material (S) and for dry storing that material at room temperature the device further comprising a circuit (16) including means for two way radio frequency communication and including writable data storage. Also disclosed is a processing method for such biometric devices, the method including the steps of: a) identifying said device by means of RF communication; b) extracting at least a portion of the biological material from the solid support of the identified device; c) analyzing the extracted biological material to obtain biometric data indicative of the biological material; and d) writing said biometric data to the data storage of the biometric device.
-
9.发明申请MICROFLUIDIC DEVICES AND ARRANGEMENTS FOR INTRODUCING REAGENTS AND BIOLOGICAL SAMPLES TO SUCH DEVICES 审中-公开用于引入试剂和这些装置的生物样品的微流体装置和装置公开(公告)号：US20160367986A1
公开(公告)日：2016-12-22
申请号：US15121147
申请日：2015-02-20
CPC分类号： B01L3/502715 , B01L2200/025 , B01L2200/027 , B01L2200/16 , B01L2300/041 , B01L2300/06 , B01L2300/069 , B01L2300/123 , G01N1/286 , G01N2001/288
摘要： A microfluidic device 100 is disclosed comprising a body112 including a biological sample S and/or reagent R receiving slot 122. The sample and reagent are carried on a solid support 10. The device 100 includes two punch assemblies 130 for removing portions of the solid support 10 and delivering them, together with the sample and/or reagent(s), to a receiving chamber 126 for subsequent processing. The device can be used for various assays including those which require just the addition of water in the reaction chamber with no pre-treatment of sample prior delivery into the chamber.
摘要翻译： 公开了一种微流体装置100，其包括主体112，其包括生物样品S和/或试剂R接收槽122.样品和试剂携带在固体支持体10上。装置100包括两个冲头组件130，用于去除部分固体支持物 并将其与样品和/或试剂一起递送到接收室126用于随后的处理。 该装置可用于各种测定，包括仅在反应室中加入水的那些试剂，而在预先将样品预先输送到室中之前。
-
10.发明申请MICROFLUIDIC DEVICES AND ARRANGEMENTS FOR SUPPLYING SUCH DEVICES WITH REAGENTS AND BIOLOGICAL SAMPLES 审中-公开用试剂和生物样品提供这些装置的微流体装置和装置公开(公告)号：US20160303562A1
公开(公告)日：2016-10-20
申请号：US15030994
申请日：2014-10-08
发明人： Jeffrey Kenneth Horton , Simon Laurence John Stubbs , Peter James Tatnell , Geraint Seymour , Cheryl Louise Potts , Alan Stuart Pierce , David Powell , Alison Myfanwy Wakefield
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/52 , B01L2200/025 , B01L2200/027 , B01L2200/10 , B01L2200/16 , B01L2300/069 , B01L2300/0803 , B01L2300/0816 , B01L2300/12 , B01L2300/126 , B01L2300/16
摘要： Disclosed is a microfluidic device including a reagent supply apparatus comprising: a solid support 12 formed preferably from cellulose fibrous material having a porosity which allows liquid flow through the material; at least one generally dry reagent 16 stored on a surface of the support at a regent location or locations; the support further being suitable for storing biological sample material 17 in a dry state at a sample location or locations, spaced from the reagent location or locations.
摘要翻译： 公开了一种微流体装置，其包括试剂供应装置，其包括：固体支持体12，优选由具有允许液体流过材料的孔隙率的纤维素纤维材料形成; 至少一个通常干燥的试剂16，储存在载体的表面上，在摄取位置或位置处; 该支持物还适于将生物样品材料17以与试剂位置间隔开的样品位置或位置处于干燥状态。
-
-
-
-
-
-
-
-
-
搜索结果
14 条记录 (耗时 0.02 秒)
