-
公开(公告)号：US20210060150A1
公开(公告)日：2021-03-04
申请号：US16986413
申请日：2020-08-06
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Stefano COLLOCA , Virginia AMMENDOLA , Fabiana GRAZIOLI , Alessandra VITELLI , Alfredo NICOSIA , Riccardo CORTESE
IPC: A61K39/04 , C12N15/86 , A61K39/12 , C12N7/00 , A61P31/06 , A61K35/761 , C07K14/005 , C07K14/35 , A61K9/00 , A61K39/39 , A61K45/00 , C12N15/85
Abstract: There is provided adenoviral vectors encoding a mycobacterial antigen derived from a chimp adenovirus, and to related aspects.
-
公开(公告)号：US20180125968A1
公开(公告)日：2018-05-10
申请号：US15848100
申请日：2017-12-20
Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
Inventor： Stefano COLLOCA , Riccardo CORTESE , Antonella FOLGORI , Alfredo NICOSIA
Abstract: The present application relates to novel administration regimens for poxviral vectors comprising nucleic acid constructs encoding antigenic proteins and invariant chains. In particular the use of said poxviral vectors for priming or for boosting an immune response is disclosed.
-
公开(公告)号：US20220220157A1
公开(公告)日：2022-07-14
申请号：US17583511
申请日：2022-01-25
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Virginia AMMENDOLA , Stefano COLLOCA , Riccardo CORTESE , Fabiana GRAZIOLI , Alfredo NICOSIA , Alessandra VITELLI
IPC: C07K14/005 , C12N15/86 , C07K14/075 , C07K14/75 , A61K39/12 , C12N15/861 , A61K39/155 , A61K39/21 , C12N7/00
Abstract: There is provided inter alia an isolated polynucleotide, wherein the polynucleotide encodes a polypeptide selected from the group consisting of: (a) a polypeptide having the amino acid sequence according to SEQ ID NO: 1, (b) a functional derivative of a polypeptide having the amino acid sequence according to SEQ ID NO: 1, wherein the functional derivative has an amino acid sequence which is at least 80% identical over its entire length to the amino acid sequence of SEQ ID NO: 1, and (c) a polypeptide having the amino acid sequence according to SEQ ID NO: 3.
-
公开(公告)号：US20160000904A1
公开(公告)日：2016-01-07
申请号：US14770510
申请日：2014-03-14
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Stefano COLLOCA , Riccardo CORTESE , Antonella FOLGORI , Alfredo NICOSIA
IPC: A61K39/29 , C12N15/86 , C07K14/74 , C12N7/00 , C07K14/005
CPC classification number: A61K39/29 , A61K39/00 , A61K2039/53 , C07K14/005 , C07K14/70539 , C07K2319/00 , C12N7/00 , C12N15/86 , C12N2710/24041 , C12N2710/24143 , C12N2770/24222 , C12N2770/24234
Abstract: The present application relates to novel administration regimens for poxviral vectors comprising nucleic acid constructs encoding antigenic proteins and invariant chains. In particular the use of said poxviral vectors for priming or for boosting an immune response is disclosed.
Abstract translation: 本申请涉及包含编码抗原蛋白和不变链的核酸构建体的痘病毒载体的新型施用方案。 特别地，公开了使用所述痘病毒载体引发或增强免疫应答。
-
公开(公告)号：US20220204566A1
公开(公告)日：2022-06-30
申请号：US17565796
申请日：2021-12-30
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Stefano COLLOCA , Virginia AMMENDOLA , Fabiana GRAZIOLI , Alessandra Franz VITELLI , Alfredo NICOSIA , Riccardo CORTESE
IPC: C07K14/005 , C12N15/86 , C07K14/075 , C07K14/75 , A61K39/12 , C12N15/861 , A61K39/155 , A61K39/21 , C12N7/00
Abstract: There is provided inter alia an isolated polynucleotide, wherein the polynucleotide encodes a polypeptide selected from the group consisting of: (a) a polypeptide having the amino acid sequence according to SEQ ID NO: 1, (b) a functional derivative of a polypeptide having the amino acid sequence according to SEQ ID NO: 1, wherein the functional derivative has an amino acid sequence which is at least 80% identical over its entire length to the amino acid sequence of SEQ ID NO: 1, and (c) a polypeptide having the amino acid sequence according to SEQ ID NO: 3.
-
Patent Agency Ranking
公开(公告)号：US20200164061A1
公开(公告)日：2020-05-28
申请号：US16782268
申请日：2020-02-05
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
Inventor： Stefano COLLOCA , Riccardo CORTESE , Antonella FOLGORI , Alfredo NICOSIA
Abstract: The present application relates to novel administration regimens for poxviral vectors comprising nucleic acid constructs encoding antigenic proteins and invariant chains. In particular the use of said poxviral vectors for priming or for boosting an immune response is disclosed.
-
公开(公告)号：US20170333550A1
公开(公告)日：2017-11-23
申请号：US15461978
申请日：2017-03-17
Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
Inventor： Stefano COLLOCA , Riccardo CORTESE , Antonella FOLGORI , Alfredo NICOSIA
CPC classification number: A61K39/29 , A61K39/12 , A61K2039/5254 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , A61K2039/6031 , C12N7/00 , C12N15/86 , C12N2710/10334 , C12N2710/10343 , C12N2710/24034 , C12N2710/24043 , C12N2710/24143 , C12N2770/24222 , C12N2770/24234
Abstract: The present application relates to novel administration regimens for poxviral vectors comprising nucleic acid constructs encoding antigenic proteins and invariant chains. In particular the use of said poxviral vectors for priming or for boosting an immune response is disclosed.
-
公开(公告)号：US20190338014A1
公开(公告)日：2019-11-07
申请号：US16327575
申请日：2017-08-23
Applicant: GLAXOSMITHKLINE BIOLOGICALS SA , UNIVERSITY OF COPENHAGEN
Inventor： Maria Rosaria BASSI , Riccardo CORTESE , Anna Morena D'ALISE , Antonella FOLGORI , Peter Johannes HOLST , Alfredo NICOSIA
Abstract: The present application provides inter alia a fusion protein comprising a polypeptide wherein the polypeptide consists of a fragment of invariant chain which is operably linked to an antigenic sequence and wherein the fragment of invariant chain consists of a portion of residues 17-97 of SEQ ID NO: 1, wherein the portion comprises at least 5 contiguous residues from residues 77-92 of SEQ ID NO: 1.
-
公开(公告)号：US20180216081A1
公开(公告)日：2018-08-02
申请号：US15747545
申请日：2016-07-25
Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
Inventor： Stefano COLLOCA , Virginia AMMENDOLA , Fabiana GRAZIOLI , Alessandra VITELLI , Alfredo NICOSIA , Riccardo CORTESE
IPC: C12N7/00 , C12N15/86 , C07K14/005 , A61K35/761 , C07K14/35 , A61K39/04 , A61P31/06
CPC classification number: A61K39/04 , A61K9/0019 , A61K35/761 , A61K39/12 , A61K39/39 , A61K45/05 , A61K2039/5256 , A61K2039/545 , A61P31/06 , C07K14/005 , C07K14/35 , C12N7/00 , C12N15/85 , C12N15/86 , C12N2710/10321 , C12N2710/10341 , C12N2710/10343 , C12N2740/16234 , C12N2760/18534
Abstract: There is provided adenoviral vectors encoding a mycobacterial antigen derived from a chimp adenovirus, and to related aspects.
-
公开(公告)号：US20180170972A1
公开(公告)日：2018-06-21
申请号：US15735839
申请日：2016-06-10
Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
Inventor： Stefano COLLOCA , Virginia AMMENDOLA , Fabiana GRAZIOLI , Alessandra Franz VITELLI , Alfredo NICOSIA , Riccardo CORTESE
IPC: C07K14/005 , C12N7/00 , A61K39/21 , A61K39/155
Abstract: There is provided inter alia an isolated polynucleotide, wherein the polynucleotide encodes a polypeptide selected from the group consisting of: (a) a polypeptide having the amino acid sequence according to SEQ ID NO: 1, (b) a functional derivative of a polypeptide having the amino acid sequence according to SEQ ID NO: 1, wherein the functional derivative has an amino acid sequence which is at least 80% identical over its entire length to the amino acid sequence of SEQ ID NO: 1, and (c) a polypeptide having the amino acid sequence according to SEQ ID NO: 3.
-
-
-
-
-
-
-
-
-
Search Results
10
records
(took 0.021 seconds)
