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公开(公告)号：US5192278A
公开(公告)日：1993-03-09
申请号：US537925
申请日：1990-06-13
CPC分类号： G02B6/4296 , A61B18/245 , A61B2017/00061 , A61B2017/22061 , A61B2018/1861 , A61B2018/2238 , G02B6/3504 , G02B6/3508 , G02B6/3512 , G02B6/3516 , G02B6/3548 , G02B6/3598
摘要： A molded fiber-optic plug for retaining optical fibers in a fixed position within a laser catheter is disclosed in which an optically polished tubular moldable plug body is used to secure a plurality of optical fibers within a laser catheter.
摘要翻译： 公开了一种用于将光纤保持在激光导管内的固定位置的模制光纤塞，其中使用光学抛光的管状可模塑塞体将多个光纤固定在激光导管内。
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公开(公告)号：US4967745A
公开(公告)日：1990-11-06
申请号：US235721
申请日：1988-08-17
CPC分类号： A61B18/245 , G02B6/4296 , A61B2017/00061 , A61B2017/22061 , A61B2018/1861 , A61B2018/2238 , G02B6/3504 , G02B6/3508 , G02B6/3512 , G02B6/3516 , G02B6/3548 , G02B6/3598
摘要： A molded fiber-optic plug for retaining optical fibers in a fixed position within a laser catheter is disclosed in which an optically polished tubular moldable plug body is used to secure a plurality of optical fibers within a laser catheter.
摘要翻译： 公开了一种用于将光纤保持在激光导管内的固定位置的模制光纤塞，其中使用光学抛光的管状可模塑塞体将多个光纤固定在激光导管内。
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公开(公告)号：US4648892A
公开(公告)日：1987-03-10
申请号：US715219
申请日：1985-03-22
申请人： Carter Kittrell , Gary B. Hayes , Michael S. Feld
发明人： Carter Kittrell , Gary B. Hayes , Michael S. Feld
IPC分类号： A61B17/22 , A61B18/20 , A61B18/24 , G02B6/42 , C03B37/025
CPC分类号： G02B6/4296 , A61B17/22 , A61B18/20 , A61B18/245 , A61B2018/00636 , G02B6/3504 , G02B6/3508 , G02B6/3512 , G02B6/3516 , G02B6/3548 , G02B6/3598
摘要： A method of forming an optical shield for a laser catheter is disclosed in which a rod of light transmissive material is optically polished and inserted into a tube of similar material and fused and the distal end of the rod is cut and the assembly is optically polished at the distal end.
摘要翻译： 公开了一种形成用于激光导管的光学屏蔽的方法，其中光透射材料棒被光学抛光并插入到类似材料的管中并且被熔化并且杆的远端被切割并且该组件被光学抛光 远端。
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公开(公告)号：US5290275A
公开(公告)日：1994-03-01
申请号：US731010
申请日：1991-07-16
IPC分类号： A61B5/00 , A61B18/20 , A61B18/22 , A61B18/24 , B23K26/03 , B23K26/067 , G02B6/04 , G02B6/14 , G02B6/24 , G02B6/35 , G02B6/42 , A61B17/32
CPC分类号： B23K26/032 , A61B1/00096 , A61B18/20 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/0084 , B23K26/067 , G02B6/04 , G02B6/241 , G02B6/4296 , A61B2018/00636 , A61B2018/2238 , G01N2021/4747 , G02B6/14 , G02B6/3504 , G02B6/3508 , G02B6/3512 , G02B6/3516 , G02B6/3548 , G02B6/3598
摘要： A laser catheter is disclosed wherein optical fibers carrying laser light are mounted in a catheter for insertion into an artery to provide controlled delivery of a laser beam for percutaneous intravascular laser treatment of atherosclerotic disease. A transparent protective shield is provided at the distal end of the catheter for mechanically diplacing intravascular blood and protecting the fibers from the intravascular contents, as well as protecting the patient in the event of failure of the fiber optics. Multiple optical fibers allow the selection of tissue that is to be removed. A computer controlled system automatically aligns fibers with the laser and controls exposure time. Spectroscopic diagnostics determine what tissue is to be removed.
摘要翻译： 公开了一种激光导管，其中携带激光的光纤被安装在用于插入动脉的导管中以提供用于经皮血管内激光治疗动脉粥样硬化疾病的激光束的受控输送。 在导管的远端处提供透明保护屏蔽，用于机械地置换血管内血液并保护纤维免受血管内内容物的影响，并且在光纤故障的情况下保护患者。 多个光纤允许选择要去除的组织。 计算机控制系统自动将光纤与激光对准并控制曝光时间。 光谱诊断确定要去除什么组织。
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公开(公告)号：US5106387A
公开(公告)日：1992-04-21
申请号：US410897
申请日：1989-09-21
IPC分类号： A61B5/00 , A61B18/20 , A61B18/22 , A61B18/24 , B23K26/03 , B23K26/067 , G02B6/04 , G02B6/14 , G02B6/24 , G02B6/35 , G02B6/42
CPC分类号： G02B6/4296 , A61B1/00096 , A61B18/20 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/0084 , G02B6/04 , G02B6/241 , A61B2018/00636 , A61B2018/2238 , G01N2021/4747 , G02B6/14 , G02B6/3504 , G02B6/3508 , G02B6/3512 , G02B6/3516 , G02B6/3548 , G02B6/3598
摘要： A method of diagnosis of the type of tissue in an artery, including distinguishing artery wall from atheromateous plaque is described, in which a catheter with one or more optical fibers is enclosed at a distal end by an optical shield transparent to light radiation and wherein the proximal end of the catheter and optical fibers are coupled to a source of optical radiation. The catheter is inserted into an artery until the optical shield is brought into contact with a suspected arterial lesion or other tissue to be diagnosed.
摘要翻译： 描述了一种诊断动脉组织类型的方法，包括区分动脉壁与动脉粥样硬化斑块，其中具有一个或多个光纤的导管在远端被通过光辐射透明的光屏蔽封闭，并且其中 导管的近端和光纤耦合到光辐射源。 将导管插入动脉中，直到光学屏蔽与疑似动脉损伤或待诊断的其他组织接触。
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公开(公告)号：US5318024A
公开(公告)日：1994-06-07
申请号：US808001
申请日：1991-12-16
IPC分类号： A61B5/00 , A61B18/20 , A61B18/22 , A61B18/24 , B23K26/03 , B23K26/067 , G02B6/04 , G02B6/14 , G02B6/24 , G02B6/35 , G02B6/42
CPC分类号： B23K26/032 , A61B1/00096 , A61B18/20 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/0084 , B23K26/0648 , B23K26/0665 , B23K26/067 , G02B6/04 , G02B6/241 , G02B6/4296 , A61B2018/00636 , A61B2018/2238 , G01N2021/4747 , G02B6/14 , G02B6/3502 , G02B6/3504 , G02B6/3508 , G02B6/3512 , G02B6/3516 , G02B6/353 , G02B6/3548 , G02B6/3588 , G02B6/3598
摘要： A laser endoscope is disclosed for generating a spectrally resolved spatial image of tissue. Fiber optics positioned within an optically shielded endoscope are used to deliver laser radiation to tissue to be imaged. Radiation returning through the fiber optics from the tissue is spectrally resolved and used to generate an image of tissue that can assist in diagnosis and treatment.
摘要翻译： 公开了一种用于产生光谱分辨的组织空间图像的激光内窥镜。 定位在光屏蔽内窥镜内的光纤用于将激光辐射传送到要成像的组织。 通过纤维光学从组织返回的辐射被光谱解析并用于产生有助于诊断和治疗的组织图像。
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公开(公告)号：US5562100A
公开(公告)日：1996-10-08
申请号：US249086
申请日：1994-05-25
申请人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand V. Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
发明人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand V. Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
CPC分类号： A61B5/0084 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/1459 , A61B2562/0238
摘要： A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.
摘要翻译： 激光诱导荧光组织的方法，其中使用激光辐射来照射和诱导正在研究的组织中的荧光以确定组织的化学组成或病理状况。 激光辐射和所检索的荧光辐射可以使用光纤阵列通过导管输送。 可以显示和分析组织的荧光光谱，以获得关于人体内组织的化学成分和医疗状况的信息。
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公开(公告)号：US4669467A
公开(公告)日：1987-06-02
申请号：US715122
申请日：1985-03-22
CPC分类号： A61B18/20 , A61B18/245 , G02B6/4296 , A61B2017/00061 , A61B2017/22038 , A61B2017/22039 , A61B2017/22048 , A61B2018/00636 , G02B6/3504 , G02B6/3508 , G02B6/3512 , G02B6/3516 , G02B6/3548 , G02B6/3598
摘要： A mode mixer is described for mixing themodes of optical fibers in a laser catheter adapted to be inserted in arteries for treatment of arterial tissue or obstructions. The mode mixer creates microbends in the fibers by physically deforming the fibers, such as by mechanically pressing the fibers against a rigid member to adjust the spot size of light exiting the fibers.
摘要翻译： 描述了用于在适于插入动脉中用于治疗动脉组织或障碍物的激光导管中混合光纤的方案的模式混合器。 模式混合器通过使纤维物理变形而在纤维中产生微弯曲，例如通过将纤维机械地压靠在刚性部件上以调节离开纤维的光的光点尺寸。
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公开(公告)号：US5419323A
公开(公告)日：1995-05-30
申请号：US720465
申请日：1991-08-29
申请人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
发明人： Carter Kittrell , Robert M. Cothren , Michael S. Feld , Joseph J. Baraga , Kyungwon An , Rebecca Richards-Kortum , Richard P. Rava , Young D. Park , Anand Mehta , Paola Taroni , Lucene Tong , Ramachandra R. Dasari
CPC分类号： A61B5/0084 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/1459 , A61B2562/0238
摘要： A method for laser induced fluorescence of tissue in which laser radiation is used to illuminate and induce fluorescence in the tissue under study to determine the chemical composition or pathologic condition of tissue. The laser radiation and the retrieved fluorescing radiation can be conveyed through a catheter using an array of optical fiber. The fluorescence spectrum of the tissue can be displayed and analyzed to obtain information regarding the chemical composition and medical condition of the tissue inside the human body.
摘要翻译： PCT No.PCT / US89 / 05174 Sec。 371日期：1993年5月7日 102（e）日期1993年5月7日PCT提交1989年11月17日PCT公布。 出版物WO90 / 06718 日期：1990年6月28日。一种激光诱导荧光组织的方法，其中使用激光辐射来照射和诱导研究组织中的荧光以确定组织的化学组成或病理状况。 激光辐射和所检索的荧光辐射可以使用光纤阵列通过导管输送。 可以显示和分析组织的荧光光谱，以获得关于人体内组织的化学成分和医疗状况的信息。
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公开(公告)号：US5199431A
公开(公告)日：1993-04-06
申请号：US417799
申请日：1989-10-04
IPC分类号： A61B5/00 , A61B18/20 , A61B18/22 , A61B18/24 , B23K26/03 , B23K26/067 , G02B6/04 , G02B6/14 , G02B6/24 , G02B6/35 , G02B6/42
CPC分类号： G02B6/4296 , A61B1/00096 , A61B18/20 , A61B18/245 , A61B5/0071 , A61B5/0075 , A61B5/0084 , G02B6/04 , G02B6/241 , A61B2018/00636 , A61B2018/2238 , G01N2021/4747 , G02B6/14 , G02B6/3504 , G02B6/3508 , G02B6/3512 , G02B6/3516 , G02B6/3548 , G02B6/3598
摘要： A laser catheter is disclosed wherein optical fibers carrying laser light are mounted in a catheter for insertion into an artery to provide controlled delivery of a laser beam for percutaneous intravascular laser treatment of atherosclerotic disease. A transparent protective shield is provided at the distal end of the catheter for mechanically diplacing intravascular blood and protecting the fibers from the intravascular contents, as well as protecting the patient in the event of failure of the fiber optics. Multiple optical fibers allow the selection of tissue that is to be removed. A computer controlled system automatically aligns fibers with the laser and controls exposure time. Spectroscopic diagnostics determine what tissue is to be removed.
摘要翻译： 公开了一种激光导管，其中携带激光的光纤被安装在用于插入动脉的导管中以提供用于经皮血管内激光治疗动脉粥样硬化疾病的激光束的受控输送。 在导管的远端处提供透明保护屏蔽，用于机械地置换血管内血液并保护纤维免受血管内内容物的影响，并且在光纤故障的情况下保护患者。 多个光纤允许选择要去除的组织。 计算机控制系统自动将光纤与激光对准并控制曝光时间。 光谱诊断确定要去除什么组织。
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