-
公开(公告)号：US20060287513A1
公开(公告)日：2006-12-21
申请号：US11352424
申请日：2006-02-10
申请人： Gary Fanger , Shannon Hirst , Davin Dillon , Teresa Foy , Raymond Houghton , David Persing , Michael Kalos
发明人： Gary Fanger , Shannon Hirst , Davin Dillon , Teresa Foy , Raymond Houghton , David Persing , Michael Kalos
CPC分类号： C07K14/4748 , A61K35/12 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/5154 , A61K2039/5156 , A61K2039/53 , A61K2039/57 , C07K14/005 , C07K14/47 , C07K14/82 , C07K16/3015 , C07K2317/21 , C07K2319/00 , C12N2710/14143 , C12N2710/24143 , C12N2740/10022 , C12N2740/14022 , C12Q1/6886 , C12Q2600/106 , C12Q2600/158
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
-
公开(公告)号：US20060083749A1
公开(公告)日：2006-04-20
申请号：US11139041
申请日：2005-05-25
申请人： Gary Fanger , Shannon Hirst , Davin Dillon , Teresa Foy , Raymond Houghton , David Persing
发明人： Gary Fanger , Shannon Hirst , Davin Dillon , Teresa Foy , Raymond Houghton , David Persing
CPC分类号： C07K14/005 , A61K35/12 , A61K38/00 , A61K39/00 , A61K48/00 , A61K2039/505 , A61K2039/5154 , A61K2039/5156 , A61K2039/53 , A61K2039/57 , C07K14/47 , C07K14/4748 , C07K14/82 , C07K16/3015 , C07K2317/21 , C07K2319/00 , C12N2710/24143 , C12N2740/14022 , C12Q1/6886 , C12Q2600/158
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
-
公开(公告)号：US20060269532A1
公开(公告)日：2006-11-30
申请号：US11344932
申请日：2006-02-01
申请人： Jiangchun Xu , Davin Dillon , Jennifer Mitcham , Susan Harlocker , Yuqiu Jiang , Robert Henderson , Michael Kalos , Gary Fanger , Marc Retter , John Stolk , Craig Day , Thomas Vedvick , Darrick Carter , Samuel Li , Aijun Wang , Yasir Skeiky , William Hepler , John Hural , Patricia McNeill , Raymond Houghton , Carlota Vinals y de Bassols , Teresa Foy , Yoshihiro Watanabe , Madeleine Meagher , Ta Deng
发明人： Jiangchun Xu , Davin Dillon , Jennifer Mitcham , Susan Harlocker , Yuqiu Jiang , Robert Henderson , Michael Kalos , Gary Fanger , Marc Retter , John Stolk , Craig Day , Thomas Vedvick , Darrick Carter , Samuel Li , Aijun Wang , Yasir Skeiky , William Hepler , John Hural , Patricia McNeill , Raymond Houghton , Carlota Vinals y de Bassols , Teresa Foy , Yoshihiro Watanabe , Madeleine Meagher , Ta Deng
CPC分类号： C07K14/4748 , A61K2039/505 , C07K16/3069 , C07K2317/34 , C12Q1/68 , C12Q1/6886 , G01N33/57434
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly prostate cancer, are disclosed. Illustrative compositions comprise one or more prostate-specific polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly prostate cancer.
-
公开(公告)号：US20070141087A1
公开(公告)日：2007-06-21
申请号：US11505569
申请日：2006-08-16
申请人： Steven Reed , Yasir Skeiky , Davin Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas Vedvick , Daniel Twardzik , Michael Lodes , Ronald Hendrickson
发明人： Steven Reed , Yasir Skeiky , Davin Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas Vedvick , Daniel Twardzik , Michael Lodes , Ronald Hendrickson
CPC分类号： C12Q1/6883 , A61K39/00 , C07K14/35 , C07K16/1289 , C07K2319/00 , C12Q1/689 , G01N33/5695
摘要： Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.
摘要翻译： 公开了用于诊断结核病的化合物和方法。 提供的化合物包括含有一种或多种结核分枝杆菌蛋白质的至少一个抗原部分的多肽和编码这种多肽的DNA序列。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的结核分枝杆菌感染。 还提供了针对这种多肽的抗体。
-
公开(公告)号：US20050181419A1
公开(公告)日：2005-08-18
申请号：US11082005
申请日：2005-03-15
申请人： Steven Reed , Yasir Skeiky , Davin Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas Vedvick , Daniel Twardzik , Michael Lodes , Ronald Hendrickson
发明人： Steven Reed , Yasir Skeiky , Davin Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas Vedvick , Daniel Twardzik , Michael Lodes , Ronald Hendrickson
IPC分类号： G01N33/569 , A61K38/00 , A61K39/00 , A61K39/04 , A61K39/395 , A61P31/06 , C07H21/02 , C07H21/04 , C07K7/00 , C07K14/35 , C07K16/12 , C07K17/00 , C07K19/00 , C12N1/19 , C12N1/21 , C12N5/10 , C12N15/09 , C12P21/08 , C12Q1/04 , C12Q1/68 , C12R1/19 , G01N33/68 , C07K16/10 , G01N33/554
CPC分类号： C12Q1/6883 , A61K39/00 , C07K14/35 , C07K16/1289 , C07K2319/00 , C12Q1/689 , G01N33/5695
摘要： Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.
-
公开(公告)号：US20050136069A1
公开(公告)日：2005-06-23
申请号：US11028898
申请日：2005-01-03
申请人： Steven Reed , Yasir Skeiky , Davin Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas Vedvick , Daniel Twardzik , Michael Lodes , Ronald Hendrickson
发明人： Steven Reed , Yasir Skeiky , Davin Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas Vedvick , Daniel Twardzik , Michael Lodes , Ronald Hendrickson
IPC分类号： G01N33/53 , A61K31/711 , A61K38/00 , A61K39/00 , A61K39/04 , A61K49/00 , A61P31/04 , A61P31/06 , A61P37/04 , C07K1/00 , C07K14/35 , C12N15/00 , C12Q1/68 , A61K39/02 , G01N33/554 , G01N33/569
CPC分类号： C07K14/35 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00
摘要： Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
摘要翻译： 公开了诱导针对结核病的保护性免疫的化合物和方法。 提供的化合物包括含有至少一种免疫原性部分的一种或多种结核分枝杆菌蛋白质和编码这种多肽的DNA分子的多肽。 这些化合物可以配制成针对结核分枝杆菌感染免疫的疫苗和/或药物组合物，或可用于诊断结核病。
-
公开(公告)号：US20060069054A1
公开(公告)日：2006-03-30
申请号：US11226869
申请日：2005-09-13
申请人： Raymond Houghton , Paul Sleath , David Persing
发明人： Raymond Houghton , Paul Sleath , David Persing
CPC分类号： C07K16/3015 , A61K35/12 , A61K38/00 , A61K39/00 , A61K2039/5154 , A61K2039/57 , C07K14/47 , C07K14/4748 , C07K2317/34 , C07K2319/00 , C12N9/00 , C12Q1/6886 , C12Q2600/156 , C12Q2600/158 , G01N33/57415 , G01N2500/00
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
-
公开(公告)号：US20120171248A1
公开(公告)日：2012-07-05
申请号：US11927558
申请日：2007-10-29
申请人： Steven G. Reed , Yasir A.W. Skeiky , Davin C. Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas S. Vedvick , Daniel R. Twardzik , Michael J. Lodes , Ronald C. Hendrickson
发明人： Steven G. Reed , Yasir A.W. Skeiky , Davin C. Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas S. Vedvick , Daniel R. Twardzik , Michael J. Lodes , Ronald C. Hendrickson
CPC分类号： C07K14/35 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00
摘要： Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
摘要翻译： 公开了诱导针对结核病的保护性免疫的化合物和方法。 提供的化合物包括含有至少一种免疫原性部分的一种或多种结核分枝杆菌蛋白质和编码这种多肽的DNA分子的多肽。 这些化合物可以配制成针对结核分枝杆菌感染免疫的疫苗和/或药物组合物，或可用于诊断结核病。
-
公开(公告)号：US07906277B2
公开(公告)日：2011-03-15
申请号：US11505569
申请日：2006-08-16
申请人： Steven R. Reed , Yasir A. W. Skeiky , Davin C. Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas S. Vedvick , Daniel R. Twardzik , Michael J. Lodes , Ronald C. Hendrickson
发明人： Steven R. Reed , Yasir A. W. Skeiky , Davin C. Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas S. Vedvick , Daniel R. Twardzik , Michael J. Lodes , Ronald C. Hendrickson
CPC分类号： C12Q1/6883 , A61K39/00 , C07K14/35 , C07K16/1289 , C07K2319/00 , C12Q1/689 , G01N33/5695
摘要： Compounds and methods for diagnosing tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one antigenic portion of one or more M. tuberculosis proteins, and DNA sequences encoding such polypeptides. Diagnostic kits containing such polypeptides or DNA sequences and a suitable detection reagent may be used for the detection of M. tuberculosis infection in patients and biological samples. Antibodies directed against such polypeptides are also provided.
摘要翻译： 公开了用于诊断结核病的化合物和方法。 提供的化合物包括含有一种或多种结核分枝杆菌蛋白质的至少一个抗原部分的多肽和编码这种多肽的DNA序列。 含有此类多肽或DNA序列的诊断试剂盒和合适的检测试剂可用于检测患者和生物样品中的结核分枝杆菌感染。 还提供了针对这种多肽的抗体。
-
公开(公告)号：US07238358B2
公开(公告)日：2007-07-03
申请号：US11028898
申请日：2005-01-03
申请人： Steven G. Reed , Yasir A. W. Skeiky , Davin C. Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas S. Vedvick , Daniel R. Twardzik , Michael J. Lodes , Ronald C. Hendrickson
发明人： Steven G. Reed , Yasir A. W. Skeiky , Davin C. Dillon , Antonio Campos-Neto , Raymond Houghton , Thomas S. Vedvick , Daniel R. Twardzik , Michael J. Lodes , Ronald C. Hendrickson
CPC分类号： C07K14/35 , A61K38/00 , A61K39/00 , A61K2039/51 , C07K2319/00
摘要： Compounds and methods for inducing protective immunity against tuberculosis are disclosed. The compounds provided include polypeptides that contain at least one immunogenic portion of one or more M. tuberculosis proteins and DNA molecules encoding such polypeptides. Such compounds may be formulated into vaccines and/or pharmaceutical compositions for immunization against M. tuberculosis infection, or may be used for the diagnosis of tuberculosis.
摘要翻译： 公开了诱导针对结核病的保护性免疫的化合物和方法。 提供的化合物包括含有至少一种免疫原性部分的一种或多种结核分枝杆菌蛋白质和编码这种多肽的DNA分子的多肽。 这些化合物可以配制成针对结核分枝杆菌感染免疫的疫苗和/或药物组合物，或可用于诊断结核病。
-
-
-
-
-
-
-
-
-
搜索结果
32 条记录 (耗时 0.041 秒)
