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    BALLOON CATHETER DEVICES WITH SHEATH COVERING
    2.
    发明申请
    BALLOON CATHETER DEVICES WITH SHEATH COVERING 审中-公开
    带有护罩的气囊导管装置

    公开(公告)号：US20110270226A1

    公开(公告)日：2011-11-03

    申请号：US13179054

    申请日：2011-07-08

    申请人： Gordon Kocur ,  Colm McGuiness

    发明人： Gordon Kocur ,  Colm McGuiness

    IPC分类号： A61L29/16 ,  A61M25/10

    CPC分类号： A61M25/1029 ,  A61L29/085 ,  A61L29/16 ,  A61L2300/416 ,  A61M25/0045 ,  A61M25/10 ,  A61M2025/0056 ,  A61M2025/1031 ,  A61M2025/105 ,  B29L2009/005 ,  C08L53/02

    摘要： Catheter devices having an expandable balloon for delivering a therapeutic agent to a body site. In one aspect, one or more sheaths are disposed around the balloon with the therapeutic agent being disposed within the sheath, being disposed over the sheath, being contained in the space between the sheath and the balloon, or being otherwise associated with the sheath. In another aspect, the balloon includes a micro-electromechanical system (MEMS) for drug delivery.

    摘要翻译： 具有用于将治疗剂递送到身体部位的可膨胀气囊的导管装置。 在一个方面，一个或多个护套设置在球囊周围，治疗剂设置在护套内，设置在护套上，被包含在护套和气囊之间的空间中，或者与护套相关联。 另一方面，气囊包括用于药物递送的微机电系统（MEMS）。

    Method of making a coated medical device
    4.
    发明授权
    Method of making a coated medical device 有权
    制造涂敷医疗器械的方法

    公开(公告)号：US07601382B2

    公开(公告)日：2009-10-13

    申请号：US10914012

    申请日：2004-08-05

    申请人： Jan Weber ,  Gordon Kocur ,  Michael Helmus ,  Maria Palasis

    发明人： Jan Weber ,  Gordon Kocur ,  Michael Helmus ,  Maria Palasis

    IPC分类号： A61L33/00 ,  B05D7/00 ,  B05D3/10 ,  A61F2/01

    CPC分类号： A61L31/16 ,  A61F2250/0068 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L2300/606

    摘要： Medical devices, such as stents, having a surface, a coating layer comprising a polymer disposed on at least a portion of the surface, and a composition comprising a biologically active material injected into or under the coating layer at one or more locations in the coating layer to form at least one pocket containing a biologically active material are disclosed. The composition may be injected using a nanometer- or micrometer-sized needle. Methods for making such medical devices are also disclosed. Using this method, a precise amount of the biologically active material may be disposed accurately and efficiently on the medical device at predefined locations.

    摘要翻译： 医疗装置，例如具有表面的支架，包括设置在表面的至少一部分上的聚合物的涂层，以及包含在涂层中的一个或多个位置处注入到涂层内或下的生物活性物质的组合物 层以形成至少一个包含生物活性材料的口袋。 可以使用纳米或微米尺寸的针注射组合物。 还公开了制造这种医疗装置的方法。 使用该方法，精确量的生物活性材料可以在预定义的位置处精确而有效地设置在医疗装置上。

    Compressive Denervation Apparatus for Innervated Renal Vasculature
    9.
    发明申请
    Compressive Denervation Apparatus for Innervated Renal Vasculature 审中-公开
    用于内源性肾血管系统的压缩去神经支配装置

    公开(公告)号：US20110264116A1

    公开(公告)日：2011-10-27

    申请号：US12980948

    申请日：2010-12-29

    申请人： Gordon Kocur ,  Dave Sogard ,  Anthony Vrba ,  Roger Hastings

    发明人： Gordon Kocur ,  Dave Sogard ,  Anthony Vrba ,  Roger Hastings

    IPC分类号： A61B17/10 ,  A61F2/82 ,  A61M29/00

    CPC分类号： A61B17/12 ,  A61B2017/00606 ,  A61B2017/00778 ,  A61B2017/00867 ,  A61F2/04 ,  A61F2/86 ,  A61F2220/0041 ,  A61F2220/0058

    摘要： Devices, systems, and methods facilitate modification of renal sympathetic nerve activity using a force generating arrangement. A device for mechanically modifying renal sympathetic nerve activity includes a contact arrangement having a shape that generally conforms to a portion of a renal artery wall and is configured for placement at the renal artery wall portion. A compression arrangement is configured to cooperate with the contact arrangement to place the wall portion of the renal artery in compression sufficient to achieve a desired reduction in renal sympathetic nerve activity. The compression arrangement and the contact arrangement are preferably configured to cooperatively place the wall portion of the renal artery in compression sufficient to irreversibly terminate renal sympathetic nerve activity.

    摘要翻译： 装置，系统和方法利用力产生装置促进肾交感神经活动的改变。 用于机械修饰肾交感神经活动的装置包括具有通常与肾动脉壁的一部分一致的形状的接触装置，并被配置为放置在肾动脉壁部分。 压缩装置被配置为与接触装置协作以将肾动脉的壁部分压缩到足以实现肾交感神经活动期望的减少。 压缩装置和接触装置优选构造成协同地将肾动脉的壁部分协调地置于足以不可逆地终止肾交感神经活动的压缩中。

    Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same
    10.
    发明申请
    Stent with channel(s) for containing and delivering a biologically active material and method for manufacturing the same 审中-公开
    具有用于包含和递送生物活性物质的通道的支架及其制造方法

    公开(公告)号：US20060122689A1

    公开(公告)日：2006-06-08

    申请号：US11337235

    申请日：2006-01-20

    申请人： Gordon Kocur ,  Timothy Girton

    发明人： Gordon Kocur ,  Timothy Girton

    IPC分类号： A61F2/06

    CPC分类号： A61F2/90 ,  A61F2/07 ,  A61F2/91 ,  A61F2/915 ,  A61F2002/072 ,  A61F2002/91541 ,  A61F2002/91558 ,  A61F2210/0076 ,  A61F2230/0013 ,  A61F2250/0067 ,  A61F2250/0068

    摘要： The invention is directed to an implantable stent prosthesis comprising a sidewall and at least one channel for containing a biologically active material. A method for making such stent prosthesis is also disclosed. In the method, at least one tube or mandrel is placed in contact with a covering material on a stent and surrounded by the covering material to form a channel. Alternatively, a channel can be formed by covering the tube or mandrel with a channel material and exposing the covered tube or mandrel to an appropriate treatment. The channel can be attached to a sidewall of a stent or attached to a strut material to form a stent wire. A method of treating an afflicted area of a body lumen by implanting the stent prosthesis is also disclosed.

    摘要翻译： 本发明涉及一种可植入支架假体，其包括侧壁和用于容纳生物活性材料的至少一个通道。 还公开了制造这种支架假体的方法。 在该方法中，至少一个管或心轴被放置成与支架上的覆盖材料接触并被覆盖材料包围以形成通道。 或者，可以通过用通道材料覆盖管或心轴并将覆盖的管或心轴暴露于适当的处理来形成通道。 通道可以附接到支架的侧壁或附接到支柱材料以形成支架线。 还公开了通过植入支架假体来治疗身体腔的折磨区域的方法。