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93 条记录 (耗时 0.028 秒)

    Compressive Denervation Apparatus for Innervated Renal Vasculature
    1.
    发明申请
    Compressive Denervation Apparatus for Innervated Renal Vasculature 审中-公开
    用于内源性肾血管系统的压缩去神经支配装置

    公开(公告)号：US20110264116A1

    公开(公告)日：2011-10-27

    申请号：US12980948

    申请日：2010-12-29

    申请人： Gordon Kocur ,  Dave Sogard ,  Anthony Vrba ,  Roger Hastings

    发明人： Gordon Kocur ,  Dave Sogard ,  Anthony Vrba ,  Roger Hastings

    IPC分类号： A61B17/10 ,  A61F2/82 ,  A61M29/00

    CPC分类号： A61B17/12 ,  A61B2017/00606 ,  A61B2017/00778 ,  A61B2017/00867 ,  A61F2/04 ,  A61F2/86 ,  A61F2220/0041 ,  A61F2220/0058

    摘要： Devices, systems, and methods facilitate modification of renal sympathetic nerve activity using a force generating arrangement. A device for mechanically modifying renal sympathetic nerve activity includes a contact arrangement having a shape that generally conforms to a portion of a renal artery wall and is configured for placement at the renal artery wall portion. A compression arrangement is configured to cooperate with the contact arrangement to place the wall portion of the renal artery in compression sufficient to achieve a desired reduction in renal sympathetic nerve activity. The compression arrangement and the contact arrangement are preferably configured to cooperatively place the wall portion of the renal artery in compression sufficient to irreversibly terminate renal sympathetic nerve activity.

    摘要翻译： 装置，系统和方法利用力产生装置促进肾交感神经活动的改变。 用于机械修饰肾交感神经活动的装置包括具有通常与肾动脉壁的一部分一致的形状的接触装置，并被配置为放置在肾动脉壁部分。 压缩装置被配置为与接触装置协作以将肾动脉的壁部分压缩到足以实现肾交感神经活动期望的减少。 压缩装置和接触装置优选构造成协同地将肾动脉的壁部分协调地置于足以不可逆地终止肾交感神经活动的压缩中。

    Compliant Cryoballoon Apparatus for Denervating Ostia of the Renal Arteries
    3.
    发明申请
    Compliant Cryoballoon Apparatus for Denervating Ostia of the Renal Arteries 审中-公开
    用于去神经支配肾动脉的冷冻兔器具

    公开(公告)号：US20110270238A1

    公开(公告)日：2011-11-03

    申请号：US12980952

    申请日：2010-12-29

    申请人： Raed Rizq ,  Dave Sogard ,  Roger Hastings

    发明人： Raed Rizq ,  Dave Sogard ,  Roger Hastings

    IPC分类号： A61B18/02

    CPC分类号： A61B18/02 ,  A61B2018/0022 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/0212 ,  A61B2018/0262

    摘要： A cryotherapy balloon catheter includes a compliant cryotherapy balloon comprising a distal balloon section dimensioned for placement within a renal artery and a proximal balloon section dimensioned to abut against an ostium of the renal artery and extend into at least a portion of the abdominal aorta. The compliant balloon has a diameter that varies non-uniformly along a length of the compliant balloon, such that a diameter at the proximal balloon section is larger than a diameter of the distal balloon section. The cryotherapy balloon catheter may be configured to deliver cryogenic therapy to at least the ostium of the renal artery sufficient to irreversibly terminate renal sympathetic nerve activity, such as by causing neurotmesis of renal nerve fibers and ganglia at the ostium of the renal artery.

    摘要翻译： 冷冻治疗气囊导管包括顺应性冷冻治疗气囊，其包括尺寸适于放置在肾动脉内的远端球囊部分和近端球囊部分，其近似球囊部分的尺寸设置成抵靠肾动脉的口并且延伸到腹主动脉的至少一部分。 顺应性球囊具有沿着柔顺气囊的长度不均匀地变化的直径，使得近端球囊部分处的直径大于远端球囊部分的直径。 冷冻治疗气球导管可以被配置为将低温治疗递送至至少肾动脉的口，足以不可逆地终止肾交感神经活动，例如通过在肾动脉的口处引起肾神经纤维和神经节的神经痛。

    Magnetically retrievable vena cava filter and retrieval device therefor
    8.
    发明授权
    Magnetically retrievable vena cava filter and retrieval device therefor 失效
    可回收的腔静脉滤器及其检索装置

    公开(公告)号：US08657848B2

    公开(公告)日：2014-02-25

    申请号：US13253480

    申请日：2011-10-05

    申请人： Mark L. Jenson ,  Roger Hastings

    发明人： Mark L. Jenson ,  Roger Hastings

    IPC分类号： A61M29/00

    CPC分类号： A61F2/01 ,  A61F2002/016 ,  A61F2210/009 ,  A61F2230/005 ,  A61F2230/0067

    摘要： The disclosure pertains to magnetically retrievable vena cava filters having a low torque associated therewith when subjected to a strong external magnetic field and retrieval devices therefor. The vena cava filter may include a magnetically permeable sphere or a spherical dipole magnet located within the spherical cavity of the apical hub wherein the spherical dipole magnet is free to rotate about any of three mutually orthogonal axes. The retrieval device is capable of substantially containing the vena cava filter in a collapsed state and includes a magnetically active member capable of interacting with the vena cava filter. The retrieval device may optionally include a supplemental mechanical latch.

    摘要翻译： 本公开涉及具有与其相关联的低扭矩的可磁回收的腔静脉过滤器，当经受强的外部磁场及其检索装置时。 腔静脉过滤器可以包括位于心尖毂的球形空腔内的导磁球体或球形偶极子磁体，其中球形偶极子磁体可以绕任意三个相互正交的轴线旋转。 检索装置能够基本上包含处于折叠状态的腔静脉过滤器，并且包括能够与腔静脉过滤器相互作用的磁性活性构件。 检索装置可以可选地包括补充机械锁存器。

    RENAL DENERVATION CATHETER AND METHOD USING pH ALTERATION
    9.
    发明申请
    RENAL DENERVATION CATHETER AND METHOD USING pH ALTERATION 审中-公开
    RENAL DENERVATION CATHETER和使用pH改变的方法

    公开(公告)号：US20120136349A1

    公开(公告)日：2012-05-31

    申请号：US13295185

    申请日：2011-11-14

    申请人： Roger Hastings

    发明人： Roger Hastings

    IPC分类号： A61B18/00

    CPC分类号： A61B18/1492 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/1472

    摘要： A catheter includes a multiplicity of leads having exposed distal elements defining an anode and a cathode positionable relative to an outer wall of a renal artery. A power supply is configured to couple to the multiplicity of leads. The power supply generates a DC current that flows between the anode and cathode to create an acidic region at the anode sufficient to cause necrosis of perivascular renal nerve tissue in the vicinity of the anode, and to create a basic region at the cathode sufficient to cause necrosis of perivascular renal nerve tissue in the vicinity of the cathode. The catheter may be configured to deliver a biocompatible electrolytic fluid to each of the cathode and anode, thereby increasing an extent of perivascular renal nerve tissue ablation in the vicinity of the cathode and anode.

    摘要翻译： 导管包括多个引线，其具有限定相对于肾动脉外壁定位的阳极和阴极的暴露的远端元件。 电源被配置为耦合到多个引线。 电源产生在阳极和阴极之间流动的直流电流，以在阳极处产生足以引起阳极附近的血管周围肾神经组织坏死的酸性区域，并且在阴极处产生足以引起 阴极附近的血管周围肾神经组织坏死。 导管可以被配置为将生物相容性电解液输送到阴极和阳极中的每一个，从而增加阴极和阳极附近的血管周围肾神经组织消融的程度。

    MAGNETICALLY RETRIEVABLE VENA CAVA FILTER AND RETRIEVAL DEVICE THEREFOR
    10.
    发明申请
    MAGNETICALLY RETRIEVABLE VENA CAVA FILTER AND RETRIEVAL DEVICE THEREFOR 失效
    VENA CAVA过滤器及其检测设备

    公开(公告)号：US20120130418A1

    公开(公告)日：2012-05-24

    申请号：US13253480

    申请日：2011-10-05

    申请人： Mark L. Jenson ,  Roger Hastings

    发明人： Mark L. Jenson ,  Roger Hastings

    IPC分类号： A61F2/01

    CPC分类号： A61F2/01 ,  A61F2002/016 ,  A61F2210/009 ,  A61F2230/005 ,  A61F2230/0067

    摘要： The disclosure pertains to magnetically retrievable vena cava filters having a low torque associated therewith when subjected to a strong external magnetic field and retrieval devices therefor. The vena cava filter may include a magnetically permeable sphere or a spherical dipole magnet located within the spherical cavity of the apical hub wherein the spherical dipole magnet is free to rotate about any of three mutually orthogonal axes. The retrieval device is capable of substantially containing the vena cava filter in a collapsed state and includes a magnetically active member capable of interacting with the vena cava filter. The retrieval device may optionally include a supplemental mechanical latch.

    摘要翻译： 本公开涉及具有与其相关联的低扭矩的可磁回收的腔静脉过滤器，当经受强的外部磁场及其检索装置时。 腔静脉过滤器可以包括位于心尖毂的球形空腔内的导磁球体或球形偶极子磁体，其中球形偶极子磁体可以绕任意三个相互正交的轴线旋转。 检索装置能够基本上包含处于折叠状态的腔静脉过滤器，并且包括能够与腔静脉过滤器相互作用的磁性活性构件。 检索装置可以可选地包括补充机械锁存器。