公开(公告)号：US20080051812A1

公开(公告)日：2008-02-28

申请号：US11461740

申请日：2006-08-01

申请人： Greg Schmitz ,  Jefferey Bleam ,  Jefffrey L. Bleich ,  Roy Leguidleguid ,  Vahid Saadat

发明人： Greg Schmitz ,  Jefferey Bleam ,  Jefffrey L. Bleich ,  Roy Leguidleguid ,  Vahid Saadat

IPC分类号： A61B17/32

CPC分类号： A61B17/320016 ,  A61B17/1604 ,  A61B17/1611 ,  A61B17/1671 ,  A61B2017/003 ,  A61B2017/32004 ,  A61B2017/320069 ,  A61B2017/32007

摘要： A device for cutting tissue in a human body may include an elongate, hollow shaft having a proximal portion and a distal portion, a bundle of flexible wires slidably disposed within at least a portion of the shaft and having a proximal end and a distal end, and an actuator coupled with the proximal portion of the shaft and the proximal end of the bundle of wires. The distal end of the bundle may be configured to facilitate cutting of tissue, and the wires of the bundle may be at least partially free to move, relative to one another, to allow a cross-sectional shape of the bundle to differ along a length from the proximal to the distal end. The actuator may be configured to move the wires back and forth through the hollow shaft to cause the distal ends of the wires to cut tissue.

摘要翻译： 用于在人体中切割组织的装置可以包括具有近端部分和远侧部分的细长的中空轴，可滑动地设置在所述轴的至少一部分内并具有近端和远端的柔性线束， 以及与所述轴的近侧部分和所述电线束的近端耦合的致动器。 束的远端可以被配置为便于切割组织，并且束的线可以至少部分地相对于彼此自由移动，以允许束的横截面形状沿长度方向不同 从近端到远端。 致动器可以被配置为通过空心轴来回移动电线，以使电线的远端切割组织。

公开(公告)号：US08430881B2

公开(公告)日：2013-04-30

申请号：US11405848

申请日：2006-04-17

申请人： Jeffery L. Bleich ,  Vahid Saadat ,  Roy Leguidleguid ,  Jefferey Bleam

发明人： Jeffery L. Bleich ,  Vahid Saadat ,  Roy Leguidleguid ,  Jefferey Bleam

IPC分类号： A61B17/00

CPC分类号： A61B17/1659 ,  A61B17/00234 ,  A61B17/02 ,  A61B17/1671 ,  A61B17/1757 ,  A61B17/320016 ,  A61B17/32002 ,  A61B17/3421 ,  A61B2017/00261 ,  A61B2017/00867 ,  A61B2017/32006 ,  A61B2017/3488 ,  A61B2090/08021

摘要： A device for modifying one or more tissues in a patient's spine may include: an elongate, at least partially flexible body having a proximal portion and a distal portion, wherein at least the distal portion has dimensions that allow it to be passed into an epidural space and between target and non-target tissues of the spine; at least one movable blade disposed along one side of the elongate body; at least one actuator coupled with the at least one blade and disposed at or near the proximal or distal portion of the body for moving the blade(s) to modify one or more target tissues, wherein the at least one actuator is configured to move the blade(s) without significantly translating the elongate body proximally or distally; and means at or near the proximal and distal portions of the elongate body for facilitating application of at least one of anchoring force and tensioning force to the body to urge the at least one blade against the target tissue.

摘要翻译： 用于修改患者脊柱中的一个或多个组织的装置可以包括：细长的至少部分柔性的身体，其具有近端部分和远端部分，其中至少远端部分具有允许其进入硬膜外腔的尺寸 和脊柱的靶和非靶组织之间; 沿着所述细长体的一侧设置的至少一个可动刀片; 至少一个致动器，其与所述至少一个叶片耦合并且设置在所述主体的近端或远端部分处或附近，用于移动所述叶片以修改一个或多个目标组织，其中所述至少一个致动器被配置成使所述至少一个致动器移动 刀片不在近侧或远端显着地平移细长体; 以及在所述细长体的近端部分和远端部分附近的装置，用于便于将至少一个锚定力和张紧力施加到身体以将至少一个刀片推向靶组织。

公开(公告)号：US20120078253A9

公开(公告)日：2012-03-29

申请号：US11405848

申请日：2006-04-17

申请人： Jeffery Bleich ,  Vahid Saadat ,  Roy Leguidleguid ,  Jefferey Bleam

发明人： Jeffery Bleich ,  Vahid Saadat ,  Roy Leguidleguid ,  Jefferey Bleam

IPC分类号： A61B17/16

CPC分类号： A61B17/1659 ,  A61B17/00234 ,  A61B17/02 ,  A61B17/1671 ,  A61B17/1757 ,  A61B17/320016 ,  A61B17/32002 ,  A61B17/3421 ,  A61B2017/00261 ,  A61B2017/00867 ,  A61B2017/32006 ,  A61B2017/3488 ,  A61B2090/08021

摘要： A device for modifying one or more tissues in a patient's spine may include: an elongate, at least partially flexible body having a proximal portion and a distal portion, wherein at least the distal portion has dimensions that allow it to be passed into an epidural space and between target and non-target tissues of the spine; at least one movable blade disposed along one side of the elongate body; at least one actuator coupled with the at least one blade and disposed at or near the proximal or distal portion of the body for moving the blade(s) to modify one or more target tissues, wherein the at least one actuator is configured to move the blade(s) without significantly translating the elongate body proximally or distally; and means at or near the proximal and distal portions of the elongate body for facilitating application of at least one of anchoring force and tensioning force to the body to urge the at least one blade against the target tissue.

摘要翻译： 用于修改患者脊柱中的一个或多个组织的装置可以包括：细长的至少部分柔性的身体，其具有近端部分和远端部分，其中至少远端部分具有允许其进入硬膜外腔的尺寸 和脊柱的靶和非靶组织之间; 沿着所述细长体的一侧设置的至少一个可动刀片; 至少一个致动器，其与所述至少一个叶片耦合并且设置在所述主体的近端或远端部分处或附近，用于移动所述叶片以修改一个或多个目标组织，其中所述至少一个致动器被配置成使所述至少一个致动器移动 刀片不在近侧或远端显着地平移细长体; 以及在所述细长体的近端部分和远端部分附近的装置，用于便于将至少一个锚定力和张紧力施加到身体以将至少一个刀片推向靶组织。

公开(公告)号：US20070213733A1

公开(公告)日：2007-09-13

申请号：US11405848

申请日：2006-04-17

申请人： Jeffery Bleich ,  Vahid Saadat ,  Roy Leguidleguid ,  Jeffery Bleam

发明人： Jeffery Bleich ,  Vahid Saadat ,  Roy Leguidleguid ,  Jeffery Bleam

IPC分类号： A61B17/16

CPC分类号： A61B17/1659 ,  A61B17/00234 ,  A61B17/02 ,  A61B17/1671 ,  A61B17/1757 ,  A61B17/320016 ,  A61B17/32002 ,  A61B17/3421 ,  A61B2017/00261 ,  A61B2017/00867 ,  A61B2017/32006 ,  A61B2017/3488 ,  A61B2090/08021

摘要： A device for modifying one or more tissues in a patient's spine may include: an elongate, at least partially flexible body having a proximal portion and a distal portion, wherein at least the distal portion has dimensions that allow it to be passed into an epidural space and between target and non-target tissues of the spine; at least one movable blade disposed along one side of the elongate body; at least one actuator coupled with the at least one blade and disposed at or near the proximal or distal portion of the body for moving the blade(s) to modify one or more target tissues, wherein the at least one actuator is configured to move the blade(s) without significantly translating the elongate body proximally or distally; and means at or near the proximal and distal portions of the elongate body for facilitating application of at least one of anchoring force and tensioning force to the body to urge the at least one blade against the target tissue.

摘要翻译： 用于修改患者脊柱中的一个或多个组织的装置可以包括：细长的至少部分柔性的身体，其具有近端部分和远端部分，其中至少远端部分具有允许其进入硬膜外腔的尺寸 和脊柱的靶和非靶组织之间; 沿着所述细长体的一侧设置的至少一个可动刀片; 至少一个致动器，其与所述至少一个叶片耦合并且设置在所述主体的近端或远端部分处或附近，用于移动所述叶片以修改一个或多个目标组织，其中所述至少一个致动器被配置成使所述至少一个致动器移动 刀片不在近侧或远端显着地平移细长体; 以及在所述细长体的近端部分和远端部分附近的装置，用于便于将至少一个锚定力和张紧力施加到身体以将至少一个刀片推向靶组织。

公开(公告)号：US09254090B2

公开(公告)日：2016-02-09

申请号：US13278820

申请日：2011-10-21

申请人： Jason Paul Watson ,  Vahid Saadat

发明人： Jason Paul Watson ,  Vahid Saadat

IPC分类号： A61B6/00 ,  A61B5/00 ,  A61B1/04

CPC分类号： A61B5/0084 ,  A61B1/043 ,  A61B5/0071 ,  A61B5/6852

摘要： Tissue contrast imaging systems are described which detect differences in tissue contrasts to obtain images of the tissue region. The systems may be used to obtain images of the cardiac tissues particularly in a blood-filled environment.

摘要翻译： 描述组织对比成像系统，其检测组织对比度的差异以获得组织区域的图像。 该系统可用于获得心脏组织的图像，特别是在充满血液的环境中。

公开(公告)号：US08814845B2

公开(公告)日：2014-08-26

申请号：US13365914

申请日：2012-02-03

申请人： Vahid Saadat ,  Sekhar S. Rao

发明人： Vahid Saadat ,  Sekhar S. Rao

IPC分类号： A61M31/00

CPC分类号： A61B1/00165 ,  A61B1/00089 ,  A61B1/00096 ,  A61B1/00147 ,  A61B1/015 ,  A61B1/05 ,  A61B1/12 ,  A61B5/0084 ,  A61B5/6882 ,  A61B5/7282 ,  A61M25/0074 ,  A61M25/0082 ,  A61M25/0084

摘要： The delivery of biological compounds to ischemic and/or infarcted tissue are described herein where such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. Additionally, any number of therapeutic tools can also be passed through the deployment catheter and into the imaging hood for performing any number of procedures on the tissue for identifying, locating, and/or accessing ischemic and/or infarcted tissue.

摘要翻译： 在本文中描述了将生物化合物递送至缺血和/或梗死组织，其中这样的系统可以包括展开导管和可展开成扩展构型的附接成像罩。 在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。 半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。 此外，任何数量的治疗工具也可以通过展开导管并进入成像罩，以在组织上执行任何数量的程序，用于识别，定位和/或获取缺血和/或梗死组织。

公开(公告)号：US08588447B2

公开(公告)日：2013-11-19

申请号：US13551158

申请日：2012-07-17

申请人： Amir A. Abolfathi ,  Vahid Saadat ,  Loc X. Phan

发明人： Amir A. Abolfathi ,  Vahid Saadat ,  Loc X. Phan

IPC分类号： H04R25/00

CPC分类号： H04R25/606 ,  A61C5/00 ,  A61C8/0093 ,  A61C8/0098 ,  B33Y70/00 ,  B33Y80/00 ,  H04R1/46 ,  H04R3/04 ,  H04R25/554 ,  H04R25/602 ,  H04R25/604 ,  H04R2225/31 ,  H04R2225/67 ,  H04R2420/07 ,  H04R2460/01 ,  H04R2460/13

摘要： Methods and apparatus for transmitting vibrations via an electronic and/or transducer assembly through a tooth or teeth are disclosed herein. The assembly may be attached, adhered, or otherwise embedded into or upon a removable oral appliance to form a hearing aid assembly. Such an oral appliance may be a custom-made device. The electronic and transducer assembly may receive incoming sounds either directly or through a receiver to process and amplify the signals and transmit the processed sounds via a vibrating transducer element coupled to a tooth or other bone structure, such as the maxillary, mandibular, or palatine bone structure.

公开(公告)号：US20120296348A1

公开(公告)日：2012-11-22

申请号：US13491273

申请日：2012-06-07

申请人： Vahid Saadat ,  Richard C. Ewers ,  Cang C. Laduca ,  Robert A. Vaughan ,  Chris Rothe ,  Kenneth J. Michlitsch

发明人： Vahid Saadat ,  Richard C. Ewers ,  Cang C. Laduca ,  Robert A. Vaughan ,  Chris Rothe ,  Kenneth J. Michlitsch

IPC分类号： A61B17/04

CPC分类号： A61F5/0086 ,  A61B17/0401 ,  A61B17/0469 ,  A61B17/0482 ,  A61B17/0483 ,  A61B17/0487 ,  A61B17/06 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/12013 ,  A61B17/1285 ,  A61B17/29 ,  A61B2017/00867 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/081 ,  A61B2017/3488

摘要： Apparatus for manipulating and securing tissue are described herein. In creating tissue folds within the body of a patient, a tissue manipulation assembly may generally have an elongate tubular member, an engagement member slidably dispose through the tubular member and a distal end adapted to engage tissue via a helical member, tissue stabilizing members positioned at the tubular member distal end which are adapted to stabilize tissue therebetween, and a delivery tube pivotable about the tissue stabilizer. The stabilizing members can be adapted to become angled relative to longitudinal axis of the elongate tubular member. Moreover, one or all the articulation controls and functions can be integrated into a singular handle assembly connectable to the tissue manipulation assembly via a rigid or flexible tubular body.

摘要翻译： 本文描述了用于操纵和固定组织的装置。 在组织折叠在患者身体内部时，组织操作组件通常可以具有细长的管状构件，可滑动地配置穿过管状构件的接合构件和适于经由螺旋构件接合组织的远端，组织稳定构件 所述管状构件远端适于在其间稳定组织，以及可围绕所述组织稳定器枢转的输送管。 稳定构件可以适于相对于细长管状构件的纵向轴线成角度。 此外，一个或所有关节运动控制和功能可以集成到通过刚性或柔性管状体连接到组织操作组件的单个手柄组件中。

公开(公告)号：US08257394B2

公开(公告)日：2012-09-04

申请号：US11036866

申请日：2005-01-14

申请人： Vahid Saadat ,  Marvin C. Elmer

发明人： Vahid Saadat ,  Marvin C. Elmer

IPC分类号： A61B17/04

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/0487 ,  A61B17/06066 ,  A61B17/064 ,  A61B17/08 ,  A61B17/10 ,  A61B17/29 ,  A61B2017/00349 ,  A61B2017/00818 ,  A61B2017/00867 ,  A61B2017/0404 ,  A61B2017/0409 ,  A61B2017/0417 ,  A61B2017/0419 ,  A61B2017/0441 ,  A61B2017/0445 ,  A61B2017/0446 ,  A61B2017/045 ,  A61B2017/0451 ,  A61B2017/0454 ,  A61B2017/0456 ,  A61B2017/0458 ,  A61B2017/0459 ,  A61B2017/0461 ,  A61B2017/0462 ,  A61B2017/0464 ,  A61B2017/0475 ,  A61B2017/0488 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/081 ,  A61B2017/3488

摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism, either within the anchor itself or positioned proximally of the anchor, may allow for the uni-directional translation of the anchor while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates cinching of the tissue plication between the anchors, and it may be utilized in one or several anchors in cinching a tissue fold.

摘要翻译： 本文公开了用于定位和固定锚固件的装置和方法。 锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。 锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。 在锚固件本身内或定位在近端处的锁定机构可以允许锚固件的单向平移，同时使锚固件被锁定在缝合线上，如果锚被拉动，推动或​​以其他方式被推入 沿缝合方向相反。 这种单向锚定锁定机构有助于锚定器之间的组织褶皱的收缩，并且可以在一个或多个锚定器中用于收紧组织褶皱。

公开(公告)号：US08216252B2

公开(公告)日：2012-07-10

申请号：US11070863

申请日：2005-03-01

申请人： Robert A. Vaughan ,  Cang C. Lam ,  Richard C. Ewers ,  Vahid Saadat

发明人： Robert A. Vaughan ,  Cang C. Lam ,  Richard C. Ewers ,  Vahid Saadat

IPC分类号： A61B17/08

CPC分类号： A61B17/0401 ,  A61B17/0487 ,  A61B17/06066 ,  A61B17/29 ,  A61B2017/00278 ,  A61B2017/0409 ,  A61B2017/0419 ,  A61B2017/0464 ,  A61B2017/0496 ,  A61B2017/06052 ,  A61B2017/06076 ,  A61B2017/2923 ,  A61B2017/2927 ,  A61B2017/3488

摘要： Tissue manipulation and securement systems are described herein. A tissue manipulation assembly is pivotably coupled to the distal end of a tubular member and has a lower jaw member and an upper jaw member pivotably coupled to the lower jaw member. A reconfigurable launch tube is also pivotably coupled to the upper jaw member and is used to urge the jaw members from a low-profile configuration to an open configuration for receiving tissue. The tissue manipulation assembly may be advanced through a shape-lockable endoscopic device, a conventional endoscope, or directly by itself into a patient. A second tool can be used in combination with the tissue manipulation assembly to engage tissue and manipulate the tissue in conjunction with the tissue manipulation assembly.

摘要翻译： 本文描述了组织操纵和固定系统。 组织操作组件可枢转地联接到管状构件的远端，并且具有下颚构件和可枢转地联接到下颚构件的上颚构件。 可重构的发射管也可枢转地联接到上钳口构件，并且用于将钳口构件从小轮廓构造推动到用于接收组织的打开构型。 组织操作组件可以通过形状可锁定内窥镜装置，常规内窥镜，或者直接自身进入患者。 第二工具可以与组织操作组件组合使用以接合组织并且与组织操作组件一起操作组织。