公开(公告)号：US20080020452A1

公开(公告)日：2008-01-24

申请号：US11458298

申请日：2006-07-18

申请人： Natasha Popovich ,  Gary Neel ,  Dennis Slomski ,  Greta Wegner

发明人： Natasha Popovich ,  Gary Neel ,  Dennis Slomski ,  Greta Wegner

IPC分类号： C12M3/00

CPC分类号： G01N33/48771

摘要： A diagnostic test strip is provided. The test strip comprises at least one electrically insulating substrate material and a plurality of electrical strip contacts disposed on the least one insulating substrate layer. The at least one electrical strip contact includes a first conductive layer disposed on the substrate, and a second conductive layer disposed on top of the first conductive layer.

摘要翻译： 提供诊断测试条。 测试条包括至少一个电绝缘基板材料和设置在至少一个绝缘基板层上的多个电条触点。 所述至少一个电条接触包括设置在所述基板上的第一导电层和设置在所述第一导电层顶部上的第二导电层。

公开(公告)号：US20070117171A1

公开(公告)日：2007-05-24

申请号：US11530542

申请日：2006-09-11

申请人： Greta Wegner ,  Natasha Popovich ,  Dennis Slomski

发明人： Greta Wegner ,  Natasha Popovich ,  Dennis Slomski

IPC分类号： C12Q1/54 ,  B05D3/00

CPC分类号： C12Q1/006 ,  C12Q1/001 ,  G01N33/521 ,  G01N33/523 ,  G01N33/525 ,  G01N33/526

摘要： A method for manufacturing a test strip is provided. The method comprises selecting a test strip substrate material and positioning the test strip substrate material a predetermined distance from a matrix material disposed on a second substrate, wherein at least one enzyme to be deposited on the test strip substrate and having glucose as an enzymatic substrate is held within the matrix material. A laser pulse is directed towards the matrix material to release at least a portion of the at least one enzyme having glucose as an enzymatic substrate from the matrix material and deposit the enzyme on the test strip substrate.

摘要翻译： 提供一种制造测试条的方法。 该方法包括选择测试条基材材料并将测试条基材材料定位在距离设置在第二基底上的基质材料预定距离，其中待沉积在测试条基材上并具有葡萄糖作为酶底物的至少一种酶是 保持在基质材料内。 将激光脉冲引向基质材料以从基质材料释放至少一部分具有作为酶底物的葡萄糖的至少一种酶，并将酶沉积在测试条基材上。

公开(公告)号：US20090057149A1

公开(公告)日：2009-03-05

申请号：US12268499

申请日：2008-11-11

申请人： Greta Wegner ,  Natasha Popovich

发明人： Greta Wegner ,  Natasha Popovich

IPC分类号： G01N27/26 ,  B05D5/12 ,  H05K3/10 ,  C25D5/02 ,  C23C14/34

CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G03F9/00

摘要： A method for manufacturing a biosensor is provided. The method may include positioning a shadow mask containing a pattern of a plurality of feature sets over a substantially planar base layer containing a plurality of registration points. The method may also include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the shadow mask and removing the shadow mask from the substantially planar base layer. Alternatively, the method may include providing a laminate structure including a substantially planar base layer containing a plurality of registration points and a photoresist layer containing a pattern of a plurality of feature sets. The method may further include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the photoresist layer and removing the photoresist layer from the substantially planar base layer.

摘要翻译： 提供一种制造生物传感器的方法。 该方法可以包括将包含多个特征集的图案的荫罩定位在包含多个对准点的基本上平面的基底层上。 该方法还可以包括通过使导电材料通过荫罩的图案并去除在基本平坦的基底层上选择性地沉积导电材料层，从而在基本平坦的基底层上形成多个特征组中的至少一个 该荫罩基本平坦的基层。 或者，该方法可以包括提供包括包含多个对准点的基本平坦的基底层和包含多个特征集的图案的光致抗蚀剂层的层压结构。 该方法可以进一步包括通过使导电材料通过光致抗蚀剂层的图案并且去除在基本上平坦的基底层上的多个特征组中的至少一个，通过选择性地将导电材料层沉积在基本平坦的基底层上 来自基本平坦的基底层的光致抗蚀剂层。

公开(公告)号：US07465597B2

公开(公告)日：2008-12-16

申请号：US11476702

申请日：2006-06-29

申请人： Greta Wegner ,  Natasha Popovich

发明人： Greta Wegner ,  Natasha Popovich

IPC分类号： H01L21/00

CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G03F9/00

摘要： A method for manufacturing a biosensor is provided. The method may include positioning a shadow mask containing a pattern of a plurality of feature sets over a substantially planar base layer containing a plurality of registration points. The method may also include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the shadow mask and removing the shadow mask from the substantially planar base layer. Alternatively, the method may include providing a laminate structure including a substantially planar base layer containing a plurality of registration points and a photoresist layer containing a pattern of a plurality of feature sets. The method may further include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the photoresist layer and removing the photoresist layer from the substantially planar base layer.

摘要翻译： 提供一种制造生物传感器的方法。 该方法可以包括将包含多个特征集的图案的荫罩定位在包含多个对准点的基本平坦的基底层上。 该方法还可以包括通过使导电材料通过荫罩的图案并去除在基本平坦的基底层上选择性地沉积导电材料层，从而在基本平坦的基底层上形成多个特征组中的至少一个 该荫罩基本平坦的基层。 或者，该方法可以包括提供包括包含多个对准点的基本平坦的基底层和包含多个特征集的图案的光致抗蚀剂层的层压结构。 该方法可以进一步包括通过使导电材料通过光致抗蚀剂层的图案并且去除在基本上平坦的基底层上的多个特征组中的至少一个，通过选择性地将导电材料层沉积在基本平坦的基底层上 来自基本平坦的基底层的光致抗蚀剂层。

公开(公告)号：US20080035478A1

公开(公告)日：2008-02-14

申请号：US11837630

申请日：2007-08-13

申请人： Greta Wegner ,  Natasha Popovich

发明人： Greta Wegner ,  Natasha Popovich

IPC分类号： C12M1/00 ,  B05D5/12

CPC分类号： C12Q1/006 ,  C12Q1/001 ,  G01N27/3272 ,  G01N33/54393 ,  G01N2333/904

摘要： The present invention includes a biosensor having a generally planar substrate including a surface texture configured to increase a surface area of the generally planar substrate. The biosensor may also include at least one conductive component at least partially formed on a portion of the surface texture. The invention also includes a method for manufacturing a biosensor. The method may include forming a surface texture on a generally planar substrate whereby the surface texture increases a surface area of the generally planar substrate. The method also includes at least partially forming at least one conductive component on a portion of the surface texture. The present invention also includes a reel having a generally planar substrate including a surface texture configured to increase a surface area of the generally planar substrate. The reel also includes at least one conductive component at least partially formed on a portion of the surface texture, and a plurality of registration points formed on the generally planar substrate.

摘要翻译： 本发明包括一种生物传感器，其具有大体上平面的基底，其包括构造成增加大致平坦的基底的表面积的表面纹理。 生物传感器还可以包括至少部分地形成在表面纹理的一部分上的至少一个导电部件。 本发明还包括一种制造生物传感器的方法。 该方法可以包括在大致平面的基板上形成表面纹理，由此表面纹理增加了大致平面的基板的表面积。 该方法还包括至少部分地在表面纹理的一部分上形成至少一个导电组件。 本发明还包括具有大致平面的基板的卷轴，该基板包括构造成增加大致平坦的基板的表面积的表面纹理。 卷轴还包括至少部分地形成在表面纹理的一部分上的至少一个导电部件和形成在大致平坦的基板上的多个对准点。

公开(公告)号：US20070266871A1

公开(公告)日：2007-11-22

申请号：US11435295

申请日：2006-05-17

申请人： Greta Wegner ,  Natasha Popovich

发明人： Greta Wegner ,  Natasha Popovich

IPC分类号： B41N1/00

CPC分类号： B41M3/006 ,  B01L3/502707 ,  B01L2200/12 ,  B01L2200/16 ,  B01L2300/0645 ,  B01L2300/0825 ,  B01L2400/0406 ,  G01N33/48771 ,  G01N33/5438 ,  H05K3/1275

摘要： The present disclosure relates to the manufacture of diagnostic test media used for measuring the concentration of analytes in a sample fluid. More specifically, the disclosure relates to using a method of microcontact printing or microtransfer molding for the manufacture of diagnostic test media.

摘要翻译： 本公开涉及用于测量样品流体中分析物浓度的诊断测试介质的制造。 更具体地，本公开涉及使用微接触印刷或微转移模制的方法来制造诊断测试介质。

公开(公告)号：US20070235346A1

公开(公告)日：2007-10-11

申请号：US11401458

申请日：2006-04-11

申请人： Natasha Popovich ,  Stephen Davies ,  Greta Wegner

发明人： Natasha Popovich ,  Stephen Davies ,  Greta Wegner

IPC分类号： C12Q1/00 ,  G01N33/487

CPC分类号： C12Q1/004

摘要： Methods and devices for determining the concentration of a constituent in a physiological sample are provided. The physiological sample is introduced into an electrochemical cell having a working and counter electrode. At least one electrochemical signal is measured based on a reaction taking place at the cell. The preliminary concentration of the constituent is then calculated from the electrochemical signal. This preliminary concentration is then multiplied by a hematocrit correction factor to obtain the constituent concentration in the sample, where the hematocrit correction factor is a function of the at least one electrochemical signal. The subject methods and devices are suited for use in the determination of a wide variety of analytes in a wide variety of samples, and are particularly suited for the determination of analytes in whole blood or derivatives thereof, where an analyte of particular interest is glucose.

摘要翻译： 提供了用于确定生理样品中成分浓度的方法和装置。 将生理样品引入具有工作电极和对电极的电化学电池中。 基于在细胞发生的反应测量至少一种电化学信号。 然后从电化学信号计算组分的初步浓度。 然后将该初步浓度乘以血细胞比容校正因子以获得样品中的组分浓度，其中血细胞比容校正因子是至少一种电化学信号的函数。 本发明的方法和装置适用于多种样品中多种分析物的测定，特别适用于测定全血或其衍生物中的分析物，其中特别感兴趣的分析物是葡萄糖。

公开(公告)号：US20080003709A1

公开(公告)日：2008-01-03

申请号：US11476702

申请日：2006-06-29

申请人： Greta Wegner ,  Natasha Popovich

发明人： Greta Wegner ,  Natasha Popovich

IPC分类号： H01L21/00

CPC分类号： C12Q1/001 ,  G01N27/3272 ,  G03F9/00

摘要： A method for manufacturing a biosensor is provided. The method may include positioning a shadow mask containing a pattern of a plurality of feature sets over a substantially planar base layer containing a plurality of registration points. The method may also include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the shadow mask and removing the shadow mask from the substantially planar base layer. Alternatively, the method may include providing a laminate structure including a substantially planar base layer containing a plurality of registration points and a photoresist layer containing a pattern of a plurality of feature sets. The method may further include forming at least one of the plurality of feature sets on the substantially planar base layer by selectively depositing a layer of a conductive material on the substantially planar base layer by passing the conductive material through the pattern of the photoresist layer and removing the photoresist layer from the substantially planar base layer.

公开(公告)号：US20120122198A1

公开(公告)日：2012-05-17

申请号：US13358948

申请日：2012-01-26

申请人： Natasha Popovich ,  Dennis Slomski ,  David Deng

发明人： Natasha Popovich ,  Dennis Slomski ,  David Deng

IPC分类号： C12M1/34 ,  B29C35/08 ,  B29C59/02 ,  B01J19/00

CPC分类号： G01N27/3272

摘要： A biosensor having a first conductive component is described, wherein the first conductive component includes at least one boundary formed by a first processing technique and at least one boundary formed by a second processing technique not the same as the first processing technique. The biosensor can also have a second conductive component including at least one boundary formed by the first processing technique and at least one boundary formed by a third processing technique not the same as the first processing technique. Further, the biosensor has a third conductive component including at least one boundary formed by the second processing technique and at least one boundary formed by the third processing technique not the same as the second processing technique.

摘要翻译： 描述具有第一导电部件的生物传感器，其中第一导电部件包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第二处理技术形成的至少一个边界。 生物传感器还可以具有包括由第一处理技术形成的至少一个边界和由与第一处理技术不相同的第三处理技术形成的至少一个边界的第二导电部件。 此外，生物传感器具有包括由第二处理技术形成的至少一个边界和由与第二处理技术不相同的第三处理技术形成的至少一个边界的第三导电成分。

公开(公告)号：US20070040567A1

公开(公告)日：2007-02-22

申请号：US11504710

申请日：2006-08-16

申请人： Natasha Popovich ,  Brent Modzelewski ,  Dennis Slomski

发明人： Natasha Popovich ,  Brent Modzelewski ,  Dennis Slomski

IPC分类号： G01R31/26

CPC分类号： G01N27/3272 ,  G01R3/00

摘要： A method of manufacturing a plurality of test strips is described where a web is formed containing conductive and base layers. A plurality of test strips are formed on the web by electrically isolating a first group of conductive components. Subsequently, a second group of conductive components are electrically isolated on the web by a different process. A test card for quality control analysis is also described, where the test card includes a plurality of attached test strip traces.

摘要翻译： 描述了制造多个测试条的方法，其中形成包含导电层和基底层的网。 通过电隔离第一组导电部件而在网状物上形成多个测试条。 随后，第二组导电组件通过不同的工艺在网上电隔离。 还描述了用于质量控制分析的测试卡，其中测试卡包括多个连接的测试条迹线。