摘要:
The present invention relates to the use of genetic variants of associated marker genes to predict an individual's susceptibility to muscular injury and muscular side effects in response to statin therapy. The present invention further relates to analytical assays and computational methods using the novel marker gene set. The present invention has utility for personalized medical treatment, drug safety, statin compliance, and prophylaxis of muscle side effect.
摘要:
A mobile device can include a distress application configured to activate a distress beacon that is broadcast as a radio frequency (RF) signal on a plurality of different protocols. Each of the plurality of different protocols can employ a different frequency band.
摘要:
Described herein is a computerised method for identifying and classifying edges in a dataset representative of an open-pit mine terrain. The method includes the step of identifying one or more surfaces of the terrain having common topological attributes (306). Then, for each surface identified, edges of the identified surface are detected (308) and each of the detected edges are classified (316) as one of a toe, crest, or other than a crest or a toe. The method also includes the step of updating the dataset (208) with the edges classified as toes or crests.
摘要:
The invention comprises a completely recessed wall-wash lighting fixture capable of being installed within a ceiling. The lighting fixture comprises a housing, which contains a lamp. The invention may comprise a lighting fixture further comprises a reflector disposed within the housing and adjacent to the first end of the housing. The invention may also comprise a flared lamp shield attached to the housing, which is capable of protecting the lighting fixture from damage. The lamp shield extends below the ceiling when the lighting fixture is installed.
摘要:
A stent scaffold combined with amniotic tissue provides for a biocompatible stent that has improved biocompatibility and hemocompatibility. The amnion tissue can be variously modified or unmodified form of amnion tissue such as non-cryo amnion tissue, solubilized amnion tissue, amnion tissue fabric, chemically modified amnion tissue, amnion tissue treated with radiation, amnion tissue treated with heat, or a combination thereof. Materials such as polymer, placental tissue, pericardium tissue, small intestine submucosa can be used in combination with the amnion tissue. The amnion tissue can be attached to the inside, the outside, both inside and outside, or complete encapsulation of the stent scaffold. In some embodiments, at least part of the covering or lining comprises a plurality of layers of amnion tissue. The method of making the biocompatible stent and its delivery and deployment are also discussed.
摘要:
A method and apparatus for providing agent assistance to a client visiting a website of an organization. The method includes the steps of collecting contact information about the visit to the website by the client and connecting the client with an agent of the organization when the collected contact information exceeds a predetermined criterion.
摘要:
The present invention provides plate spinner systems and devices, and methods of using such systems and devices. In preferred embodiments, the systems and devices contain one or more of the following features: a manual power generating component (e.g. a hand crank power supply); a rotor assembly composed of a rotor with brackets for securing a sample holding device such as a sample processing device or a micro-titer plate; a rotor hub that supports nearly all of the weight of the rotor assembly; a manually operated brake; and a kettle cover containing a rotor tachometer.
摘要:
A method of producing male or female sterile plants comprising the steps of transforming plant material with a polynucleotide which encodes at least one enzyme which reacts with a non-phytotoxic substance to produce a phytotoxic one, and regenerating the thus transformed material into a plant, wherein the said non-phytotoxic substance is applied to the plant up to the time of male or female gamete formation and/or maturation, so that the non-phytotoxic substance provides for the production of a phytotoxic one which selectively prevents the formation of or otherwise renders the said gametes non-functional, wherein the enzyme is expressed preferentially in either male or female reproductive structures, characterised in that (i) the non-phytotoxic substance is selected from the group consisting of ester derivatives of non-phosphonate herbicides which herbicides are directly phytotoxic to non-green tissue, D-alpha amino acids, peptide derivatives of non-protein D-alpha amino acids, S-enantiomers of aryloxyphenoxypropionates and S-enantiomers of ester derivatives of aryloxyphenoxypropionates and (ii) the enzyme is selected from the group consisting of carboxylesterases, D-amino acid oxidases, D-amino acid dehydrogenases, D-amino acid racemases, 2-arylpropionyl-CoA epimerases, alpha-methylacyl-CoA racemases, thioesterases and acyl-CoA synthetases.
摘要:
A method and apparatus for a calibrated variable phase offset timing between synchronous clock subdomains is described. In one embodiment, the invention is an apparatus. The apparatus includes a first subsystem and a second subsystem coupled to the first subsystem. The apparatus also includes a clock signal generator coupled to the first subsystem and coupled to the second subsystem. The clock signal generator is to supply a first clock to the first subsystem and to supply a second clock to the first subsystem and to supply a third clock to the second subsystem. Each of the first clock, the second clock and the third clock are derived from a common clock, the first clock having a first predetermined phase offset relative to the third clock, and the second clock having a second predetermined phase offset relative to the third clock. The first predetermined phase offset and the second predetermined phase offset are adjustable based on performance characteristics of the first subsystem and performance characteristics of the second subsystem.
摘要:
A device for maintaining cooperating plugs on a pair of electrical cords connected comprising a generally elongate body adapted to enclose the plugs of a pair of electrical cords; said body comprising at least two cooperating members which, when engaged, form an enclosure for the plugs; at least two pairs of appendages affixed to the inside of the cooperating members; said appendages adapted to grip both electical cords so as to maintain the plugs in a connected relationship; and means to selectively engage and disengage the members comprising the body.