公开(公告)号：US20130148461A1

公开(公告)日：2013-06-13

申请号：US13521313

申请日：2011-01-10

申请人： Guo-Zhong Li ,  Kurt Joudrey ,  Ryszard Feldman ,  John Heden ,  Michael Jackson ,  John Angelosanto

发明人： Guo-Zhong Li ,  Kurt Joudrey ,  Ryszard Feldman ,  John Heden ,  Michael Jackson ,  John Angelosanto

IPC分类号： B01F15/04

CPC分类号： B01F15/0404 ,  B01D15/166 ,  G01N30/34 ,  G01N2030/347 ,  G05D11/138

摘要： Embodiments of the present invention are directed to a devices and methods for forming a desired miture of two or more fluids in a conduit. The devices and methods feature control means having error monitoring means and in response to an error event the control means organizes the packet-group of command signals to form at least one first error packet group. The error event occurs during the period of time in which the at least one error packet-group is received by a selectable value. The at least one error packet-group comprising an order or timing of first command signals and second commands signals to minimize deviation from the desired mixture in the flow of mixture-packets forming the desired mixture of two or more fluids in a conduit during the error event.

摘要翻译： 本发明的实施例涉及一种用于在管道中形成两种或更多种流体的所需要的装置和方法。 所述设备和方法具有控制装置，其具有错误监视装置，并且响应于错误事件，控制装置组织命令信号的分组组以形成至少一个第一错误分组组。 在通过可选择的值接收至少一个错误分组组的时间段期间发生错误事件。 所述至少一个错误分组组包括第一命令信号和第二命令信号的顺序或定时，以最小化在错误期间在导管中形成两个或更多个流体的期望混合物的混合物包流中的期望混合物的偏差 事件。

公开(公告)号：US20120287746A1

公开(公告)日：2012-11-15

申请号：US13519833

申请日：2011-01-11

申请人： John Angelosanto ,  Charles T. Murphy ,  Kurt Joudrey ,  Kara O'Donnell ,  Paul E. Linderson ,  Michael LeBeau ,  Wade P. Leveille ,  Michael R. Jackson

发明人： John Angelosanto ,  Charles T. Murphy ,  Kurt Joudrey ,  Kara O'Donnell ,  Paul E. Linderson ,  Michael LeBeau ,  Wade P. Leveille ,  Michael R. Jackson

IPC分类号： B01F15/04 ,  B81B1/00

CPC分类号： G01N30/32 ,  B01D15/166 ,  B29B7/007 ,  B29B7/385 ,  G01N30/24 ,  G01N30/34 ,  G01N2030/201 ,  G01N2030/326 ,  G01N2030/347

摘要： Low-pressure mixing of fluids includes a pumping system having a pump and a fluidic inlet port through which fluid is introduced to the pump. A fluid proportioning system is in fluidic communication with the fluidic inlet port of the pumping system to deliver thereto a fluid stream comprised of multiple different fluids. The fluid proportioning system includes a manifold having a plurality of inlet ports, an outlet port connected by tubing to the fluidic inlet port of the pumping system, and an outlet conduit providing an internal fluidic passageway to the outlet port. Each inlet port is fluidically coupled to a fluid source to receive one of the different fluids and to the outlet conduit to deliver thereto the received fluid for delivery out of the manifold through the outlet port to the fluidic inlet port of the pumping system.

摘要翻译： 液体的低压混合包括具有泵和流体入口的泵送系统，流体通过该入口进入泵。 流体配比系统与泵送系统的流体入口端口流体连通，以向其输送由多种不同流体组成的流体流。 流体分配系统包括具有多个入口端口的歧管，通过管道连接到泵送系统的流体入口端口的出口端口以及向出口端口提供内部流体通道的出口管道。 每个入口端口流体耦合到流体源以接收不同流体中的一种和出口管道，以将其接收到的流体输送到歧管通过出口到达泵送系统的流体入口端口。

公开(公告)号：US09645123B2

公开(公告)日：2017-05-09

申请号：US13519833

申请日：2011-01-11

申请人： John Angelosanto ,  Charles T. Murphy ,  Kurt Joudrey ,  Kara O'Donnell ,  Paul E. Linderson ,  Michael LeBeau ,  Wade P. Leveille ,  Michael R. Jackson

发明人： John Angelosanto ,  Charles T. Murphy ,  Kurt Joudrey ,  Kara O'Donnell ,  Paul E. Linderson ,  Michael LeBeau ,  Wade P. Leveille ,  Michael R. Jackson

IPC分类号： G01N30/32 ,  G01N30/34 ,  B29B7/00 ,  B29B7/38 ,  G01N30/24 ,  G01N30/20 ,  B01D15/16

CPC分类号： G01N30/32 ,  B01D15/166 ,  B29B7/007 ,  B29B7/385 ,  G01N30/24 ,  G01N30/34 ,  G01N2030/201 ,  G01N2030/326 ,  G01N2030/347

摘要： Low-pressure mixing of fluids includes a pumping system having a pump and a fluidic inlet port through which fluid is introduced to the pump. A fluid proportioning system is in fluidic communication with the fluidic inlet port of the pumping system to deliver thereto a fluid stream comprised of multiple different fluids. The fluid proportioning system includes a manifold having a plurality of inlet ports, an outlet port connected by tubing to the fluidic inlet port of the pumping system, and an outlet conduit providing an internal fluidic passageway to the outlet port. Each inlet port is fluidically coupled to a fluid source to receive one of the different fluids and to the outlet conduit to deliver thereto the received fluid for delivery out of the manifold through the outlet port to the fluidic inlet port of the pumping system.

公开(公告)号：US08176932B2

公开(公告)日：2012-05-15

申请号：US12652271

申请日：2010-01-05

申请人： John Angelosanto ,  Joseph A. Luongo ,  Frank Rubino

发明人： John Angelosanto ,  Joseph A. Luongo ,  Frank Rubino

IPC分类号： F16L35/00

CPC分类号： F16J15/004 ,  F04B53/04 ,  F04B53/164 ,  Y10T137/0452 ,  Y10T137/5762 ,  Y10T137/9247

摘要： Embodiments of the present invention are directed to methods and devices for conveying or containing fluids under pressure in which seals are provided with a defined path to vent fluid in the event of a seal failure.

摘要翻译： 本发明的实施例涉及用于在压力下输送或容纳流体的方法和装置，其中在密封件发生故障的情况下，密封件具有限定的排放流体路径。

公开(公告)号：US20080260558A1

公开(公告)日：2008-10-23

申请号：US10598310

申请日：2005-03-04

申请人： Joseph A. Luongo ,  John Angelosanto ,  Frank Rubino ,  Stanley P. Pensak Jr. ,  David J. First ,  Jean-Pierre Pugnaire ,  Richard R. Venable

发明人： Joseph A. Luongo ,  John Angelosanto ,  Frank Rubino ,  Stanley P. Pensak Jr. ,  David J. First ,  Jean-Pierre Pugnaire ,  Richard R. Venable

IPC分类号： F04B39/00 ,  G01L9/04

CPC分类号： F04B53/162 ,  F04B53/16 ,  F04B2205/03 ,  G01N2030/326

摘要： Embodiments of the present invention are directed to method and devices for measuring the pressure of a pump chamber in which no internal opening or connections are needed. One embodiment of the present invention is directed to an apparatus for pumping fluid. The apparatus comprises at least one housing having a transducer surface. The transducer surface has a thickness exhibiting measurable deformation upon the chamber holding a fluid under pressure such that the transducer surface has a first position at which the chamber is at one pressure and a second position at which the chamber is at a second pressure. A strain sensor is affixed to the transducer surface producing; at least one signal upon the transducer surface assuming the first position and at least one signal upon the transducer surface assuming the second position to function as an integrated pressure transducer.

摘要翻译： 本发明的实施例涉及用于测量不需要内部开口或连接的泵室的压力的方法和装置。 本发明的一个实施例涉及一种用于泵送流体的装置。 该装置包括具有换能器表面的至少一个壳体。 换能器表面具有在腔室上保持流体的压力下呈现可测量变形的厚度，使得换能器表面具有腔室处于一个压力的第一位置和腔室处于第二压力的第二位置。 应变传感器固定在传感器表面上; 在换能器表面上的至少一个信号假设第一位置，并且在换能器表面上的至少一个信号假设第二位置用作集成的压力换能器。

公开(公告)号：US20140044577A1

公开(公告)日：2014-02-13

申请号：US14007392

申请日：2012-04-17

申请人： Joshua A. Shreve ,  Neal B. Almeida ,  John Angelosanto ,  Joseph A. Luongo

发明人： Joshua A. Shreve ,  Neal B. Almeida ,  John Angelosanto ,  Joseph A. Luongo

IPC分类号： F04B7/00

CPC分类号： F04B7/0088 ,  F04B15/00 ,  F04B53/007 ,  F04B53/02 ,  F04B53/164

摘要： Described are embodiments of a pump that can be used, for example, in liquid chromatography applications. The pump includes a seal wash housing, pump head and seal assembly. A wear-resistant coating applied to a sealing surface or gland of the pump head or seal wash housing improves the hardness and chemical compatibility of the sealing surface. Oxidation of the sealing surface is reduced so that the sealing surface is less abrasive to the seal assembly and the lifetime of the seal assembly is increased.

摘要翻译： 描述了可以用于例如液相色谱应用中的泵的实施方案。 该泵包括一个密封清洗外壳，泵头和密封组件。 施加到泵头或密封清洗壳体的密封表面或密封套上的耐磨涂层改善了密封表面的硬度和化学相容性。 减小密封表面的氧化，使得密封表面对密封组件的磨损较小，并且密封组件的寿命增加。

公开(公告)号：US20130340609A1

公开(公告)日：2013-12-26

申请号：US13985967

申请日：2012-03-09

申请人： Joshua A. Shreve ,  Neil Almeida ,  John Angelosanto

发明人： Joshua A. Shreve ,  Neil Almeida ,  John Angelosanto

IPC分类号： F04B53/16

CPC分类号： F04B53/164 ,  F04B13/00 ,  F04B53/007 ,  F04B53/06 ,  G01N30/32 ,  G01N2030/326

摘要： Pumps used in liquid chromatography applications employ actuators for pressurizing and moving liquid. An actuator includes a pump head having a chamber, a gland, a movable rod extending through the gland into the chamber of the pump head, and a plunger seal disposed in the gland around the rod for sealing against fluidic leakage from the chamber. The plunger seal has an annular flange that provides an OD (outer diameter) seal against the gland. The flange defines a seal cavity. The pump head further includes an outlet port and an outlet channel. One end of the outlet channel is in communication with the outlet port and the other end of the outlet channel opens into the seal cavity of the plunger seal. The outlet channel provides a flow path for liquid in the chamber to travel towards the outlet port in response to movement of the rod.

摘要翻译： 用于液相色谱应用的泵使用用于加压和移动液体的致动器。 致动器包括泵头，其具有腔室，密封套，通过压盖延伸到泵头的腔室中的活动杆以及设置在杆周围的压盖中的活塞密封件，用于密封以防止来自腔室的流体泄漏。 柱塞密封件具有环形凸缘，其向压盖提供OD（外径）密封。 凸缘限定密封腔。 泵头还包括出口和出口通道。 出口通道的一端与出口连通，出口通道的另一端通向柱塞密封件的密封腔。 出口通道为腔室中的液体提供流动路径，以响应于棒的移动朝向出口移动。

公开(公告)号：US08297589B2

公开(公告)日：2012-10-30

申请号：US12296461

申请日：2007-04-11

申请人： Theodore Dourdeville ,  Frank A. Rubino ,  Kurt D. Joudrey ,  Joseph A. Luongo ,  John Angelosanto

发明人： Theodore Dourdeville ,  Frank A. Rubino ,  Kurt D. Joudrey ,  Joseph A. Luongo ,  John Angelosanto

IPC分类号： F16K31/02

CPC分类号： F16K15/183 ,  F04B7/0076 ,  F16K31/047 ,  F16K37/0041 ,  Y10T137/0318

摘要： A valve including a linear positioning component operatively connected to a valve body and an actuating element.

摘要翻译： 一种阀，包括可操作地连接到阀体和致动元件的线性定位部件。

公开(公告)号：US09377011B2

公开(公告)日：2016-06-28

申请号：US14007392

申请日：2012-04-17

申请人： Joshua A. Shreve ,  Neal B. Almeida ,  John Angelosanto ,  Joseph A. Luongo

发明人： Joshua A. Shreve ,  Neal B. Almeida ,  John Angelosanto ,  Joseph A. Luongo

IPC分类号： F04B7/00 ,  F04B15/00 ,  F04B53/00 ,  F04B53/02 ,  F04B53/16

CPC分类号： F04B7/0088 ,  F04B15/00 ,  F04B53/007 ,  F04B53/02 ,  F04B53/164

摘要： Described are embodiments of a pump that can be used, for example, in liquid chromatography applications. The pump includes a seal wash housing, pump head and seal assembly. A wear-resistant coating applied to a sealing surface or gland of the pump head or seal wash housing improves the hardness and chemical compatibility of the sealing surface. Oxidation of the sealing surface is reduced so that the sealing surface is less abrasive to the seal assembly and the lifetime of the seal assembly is increased.

摘要翻译： 描述了可以用于例如液相色谱应用中的泵的实施方案。 该泵包括一个密封清洗外壳，泵头和密封组件。 施加到泵头或密封清洗壳体的密封表面或密封套上的耐磨涂层改善了密封表面的硬度和化学相容性。 减小密封表面的氧化，使得密封表面对密封组件的磨损较小，并且密封组件的寿命增加。

公开(公告)号：US08333568B2

公开(公告)日：2012-12-18

申请号：US10598310

申请日：2005-03-04

申请人： Joseph A. Luongo ,  John Angelosanto ,  Frank Rubino ,  Stanley P. Pensak, Jr. ,  David J. First ,  Jean-Pierre Pugnaire ,  Richard R. Venable

发明人： Joseph A. Luongo ,  John Angelosanto ,  Frank Rubino ,  Stanley P. Pensak, Jr. ,  David J. First ,  Jean-Pierre Pugnaire ,  Richard R. Venable

IPC分类号： F04B49/00

CPC分类号： F04B53/162 ,  F04B53/16 ,  F04B2205/03 ,  G01N2030/326

摘要： Embodiments of the present invention are directed to method and devices for measuring the pressure of a pump chamber in which no internal opening or connections are needed. One embodiment of the present invention is directed to an apparatus for pumping fluid. The apparatus comprises at least one housing having a transducer surface. The transducer surface has a thickness exhibiting measurable deformation upon the chamber holding a fluid under pressure such that the transducer surface has a first position at which the chamber is at one pressure and a second position at which the chamber is at a second pressure. A strain sensor is affixed to the transducer surface producing; at least one signal upon the transducer surface assuming the first position and at least one signal upon the transducer surface assuming the second position to function as an integrated pressure transducer.

摘要翻译： 本发明的实施例涉及用于测量不需要内部开口或连接的泵室的压力的方法和装置。 本发明的一个实施例涉及一种用于泵送流体的装置。 该装置包括具有换能器表面的至少一个壳体。 换能器表面具有在腔室上保持流体的压力下呈现可测量变形的厚度，使得换能器表面具有腔室处于一个压力的第一位置和腔室处于第二压力的第二位置。 应变传感器固定在传感器表面上; 在换能器表面上的至少一个信号假设第一位置，并且在换能器表面上的至少一个信号假设第二位置用作集成的压力换能器。