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    Antibiotic LL-E19085
    4.
    发明授权
    Antibiotic LL-E19085 失效
    抗生素LL-E19085

    公开(公告)号：US5096907A

    公开(公告)日：1992-03-17

    申请号：US639496

    申请日：1991-01-09

    申请人： Guy T. Carter ,  Joseph J. Goodman ,  David P. Labeda

    发明人： Guy T. Carter ,  Joseph J. Goodman ,  David P. Labeda

    IPC分类号： A23K20/195 ,  C07D498/14 ,  C12P17/18

    CPC分类号： C07D498/14 ,  A23K20/195 ,  C12P17/188 ,  Y10S435/867

    摘要： This disclosure describes novel antibacterial agents designated LL-E10985.alpha., LL-E19085.beta., LL-E19085.gamma., LL-E19085.gamma. and LL-E19085.zeta., having the structure: ##STR1## their production by aerobic fermentation of a new subspecies of Micromonospora citrea NRRL 18351 and mutants thereof, and the isolation and purification thereof.

    摘要翻译： 本公开描述了新的抗菌剂，其命名为LL-E10985α，LL-E19085β，LL-E19085γ，LL-E19085γ和LL-E19085ζ，具有以下结构：其通过需氧发酵的新亚种小单孢菌 柠檬酸NRRL 18351及其突变体，并进行分离和纯化。

    Agents and method of production thereof
    9.
    发明授权
    Agents and method of production thereof 失效
    试剂及其生产方法

    公开(公告)号：US5106994A

    公开(公告)日：1992-04-21

    申请号：US732252

    申请日：1985-05-10

    申请人： Guy T. Carter ,  Margaret J. Torrey ,  Michael Greenstein

    发明人： Guy T. Carter ,  Margaret J. Torrey ,  Michael Greenstein

    IPC分类号： A01N63/02 ,  C07H19/01 ,  C12P1/06

    CPC分类号： C07H19/01 ,  A01N63/02 ,  C12P1/06 ,  Y10S435/886

    摘要： This invention relates to new agents designated LL-F28249.alpha., LL-F28249.beta., LL-F28249.gamma., LL-F28249.delta., LLF28249.epsilon., LL-F28249.zeta., LL-F28249.eta., LL-F28249.theta., LL-F28249.iota., LL-F28249.kappa., LL-F28249.lambda., LL-F28249.mu., LL-F28249.nu., and LL-F28249.omega., to their production by fermentation, to methods for their recovery and concentration from crude solutions, to processes for their purification and to pharmaceutically and pharmacologically-acceptable salts thereof. The present invention includes within its scope the biologically pure culture which produces there agents, derived from a newly-discovered and previously uncultured microorganism, Streptomyces cyaneogriseus subsp. noncyanogenus, NRRL 15773.

    摘要翻译： 本发明涉及称为LL-F28249α，LL-F28249β，LL-F28249γ，LL-F28249Δ，LLF28249ε，LL-F28249zeta，LL-F28249 eta，LL-F28249θ，LL-F28249Iota， LL-F28249 kappa，LL-F28249 lambda，LL-F28249 mu，LL-F28249 nu和LL-F28249 omega，通过发酵生产，从其回收和从粗溶液中浓缩的方法，其纯化方法和 其药学上可接受的盐。 本发明在其范围内包括衍生自新发现和先前未培养的微生物Streptomyces cyaneogriseus subsp。的生物纯培养物。 非花青素，NRRL 15773。

    Biologically pure culture of the microorganism, streptomyces cyaneogriseus subspecies noncyanogenus, or a mutant thereof
    10.
    发明授权
    Biologically pure culture of the microorganism, streptomyces cyaneogriseus subspecies noncyanogenus, or a mutant thereof 失效
    微生物的生物学纯培养物，非花青素链霉菌亚种，或其突变体

    公开(公告)号：US5418168A

    公开(公告)日：1995-05-23

    申请号：US927581

    申请日：1992-08-10

    申请人： Guy T. Carter ,  Margaret J. Torrey ,  Michael Greenstein

    发明人： Guy T. Carter ,  Margaret J. Torrey ,  Michael Greenstein

    IPC分类号： A01N63/02 ,  C07H19/01 ,  C12P1/06 ,  C12N1/20 ,  C12P17/18

    CPC分类号： C07H19/01 ,  A01N63/02 ,  C12P1/06 ,  Y10S435/88 ,  Y10S435/886

    摘要： This invention relates to new agents designated LL-F28249.alpha., LL-F28249.beta., LL-F28249.gamma., LL-F28249.delta., LL-F28249.epsilon., LL-F28249.zeta., LL-F28249.eta., LL-F28249.theta., LL-F28249.iota., LL-F28249.kappa., LL-F28249.lambda., LL-F28249.mu., LL-F28249.nu., and LL-F28249.omega., to their production by fermentation, to methods for their recovery and concentration from crude solutions, to processes for their purification and to pharmaceutically and pharmacologically-acceptable salts thereof. The present invention includes within its scope the biologically pure culture which produces there agents, derived from a newly-discovered and previously uncultured microorganism, Streptomyces cyaneogriseus subsp. noncyanogenus, NRRL 15773.

    摘要翻译： 本发明涉及称为LL-F28249α，LL-F28249β，LL-F28249γ，LL-F28249Δ，LL-F28249ε，LL-F28249zeta，LL-F28249 eta，LL-F28249θ，LL-F28249 iota，LL-F28249 kappa，LL-F28249λ，LL-F28249 mu，LL-F28249nu和LL-F28249 omega，通过发酵生产，其从粗溶液中回收和浓缩的方法，以及其纯化方法 以及其药学上和药理上可接受的盐。 本发明在其范围内包括衍生自新发现和先前未培养的微生物Streptomyces cyaneogriseus subsp。的生物纯培养物。 非花青素，NRRL 15773。