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公开(公告)号:US20240099586A1
公开(公告)日:2024-03-28
申请号:US18266355
申请日:2021-12-16
Applicant: HAMAMATSU PHOTONICS K.K. , TOKYO MEDICAL UNIVERSITY
Inventor: Tomomi IIDA , Yukio UEDA , Takafumi HAMAOKA
IPC: A61B5/00 , G01J3/42 , G01N21/3563
CPC classification number: A61B5/0075 , A61B5/4872 , A61B5/7203 , G01J3/42 , G01N21/3563 , G01J2003/2859
Abstract: An analysis apparatus includes a light emission unit configured to emit measurement light including light in a 900 nm wavelength band to a sample, a light detection unit configured to acquire spectrum data of reflected light in the sample, a data processing unit configured to perform a noise removing process on the spectrum data, a first determination unit configured to store a PLS regression model associated with prediction of an amount of triglyceride in the sample and to determine an amount of triglyceride in the sample by applying the spectrum data subjected to the noise removing process to the PLS regression model, and a second determination unit configured to store data indicating a correlation with an amount of triglyceride in the sample and to determine an amount of brown adipose tissue or beige fat in the sample based on the data and the amount of triglyceride determined by the first determination unit.
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公开(公告)号:US20240374182A1
公开(公告)日:2024-11-14
申请号:US18564771
申请日:2022-03-17
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Norihiro SUZUKI , Yukio UEDA
IPC: A61B5/1455
Abstract: A probe unit is a probe unit used to measure hemoglobin dynamics inside a subject, and the probe unit includes a main body having flexibility, a first probe attached to the main body and having a first face from which a first light emitting portion for irradiating the subject with light is exposed, a second probe attached to the main body to face the first probe and having a second face from which a first light incidence portion for detecting light propagated inside the subject is exposed, a first light shielding member having light shielding properties, containing an elastic material, and attached to the first face to surround an emission axis of the first light emitting portion, and a second light shielding member having light shielding properties, containing an elastic material, and attached to the second face to surround an incidence axis of the first light incidence portion.
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公开(公告)号:US20200061550A1
公开(公告)日:2020-02-27
申请号:US16531229
申请日:2019-08-05
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Etsuko OHMAE , Kenji YOSHIMOTO , Hiroko WADA , Yukio UEDA
IPC: B01F3/08 , B01F3/22 , G01N21/359
Abstract: The present invention relates to the phantom comprises water, an oil, an emulsifier and a water coagulating agent, and having a scattering coefficient of 5 to 20 cm−1 at a wavelength of 750 to 1000 nm.
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公开(公告)号:US20200061552A1
公开(公告)日:2020-02-27
申请号:US16534227
申请日:2019-08-07
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Etsuko OHMAE , Kenji YOSHIMOTO , Hiroko WADA , Yukio UEDA
IPC: B01F3/08 , G01N21/359 , G01N21/27
Abstract: The present invention relates to the phantom comprises water, an oil, an emulsifier and an oil coagulating agent.
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公开(公告)号:US20180084982A1
公开(公告)日:2018-03-29
申请号:US15714048
申请日:2017-09-25
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Daisuke YAMASHITA , Yutaka YAMASHITA , Yukio UEDA , Yoshinori TAMAOKI
Abstract: A device for radiating pulsed light toward a thrombus in a blood vessel includes a light source configured to output monitoring light to be radiated into the blood vessel, a light detector configured to detect returned light of the monitoring light and output a detection signal, and a computer configured to acquire a time waveform, which is a change in an intensity of the returned light over time, based on the detection signal, wherein the computer is configured to obtain a parameter on the basis of the time waveform and evaluates a reaction in the blood vessel according to the radiation of the pulsed light on the basis of the parameter.
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公开(公告)号:US20190189260A1
公开(公告)日:2019-06-20
申请号:US16324959
申请日:2017-08-08
Applicant: SAITAMA MEDICAL UNIVERSITY , HAMAMATSU PHOTONICS K.K.
Inventor: Shigeto UEDA , Toshiaki SAEKI , Yukio UEDA
IPC: G16H20/10 , A61B5/1455 , A61B5/00
CPC classification number: G16H20/10 , A61B5/1455 , A61B5/14551 , A61B5/4312 , A61B10/00
Abstract: A method of evaluating a therapeutic effect of a drug in a cancer patient, comprising a comparison step of comparing a first absolute hemoglobin concentration in a sternum portion of the cancer patient before administration of the drug and a second absolute hemoglobin concentration in the sternum portion of the cancer patient after administration of the drug; and an evaluation step of evaluating the therapeutic effect of the drug in the cancer patient based on the result of comparison performed through the comparison step.
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公开(公告)号:US20220317036A1
公开(公告)日:2022-10-06
申请号:US17615896
申请日:2020-06-01
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor: Kenji YOSHIMOTO , Yukio UEDA
IPC: G01N21/359 , G01N21/3563 , G01N33/44
Abstract: A phantom design method includes a correction step and a calculation step. In the correction step, an absorption spectrum of a target of spectroscopic measurement by a near infrared spectrometer is corrected based on a refractive index of the target and a refractive index of a resin used as a base material of a phantom to generate a corrected absorption spectrum. In the calculation step, based on an absorption spectrum of the resin and an absorption spectrum of each of N types of dyes, a concentration of each of the N types of dyes to be contained in the base material is calculated such that an absorption spectrum of the phantom constituted by the base material containing the N types of dyes approximates the corrected absorption spectrum in a predetermined wavelength range of a near infrared region.
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公开(公告)号:US20190209012A1
公开(公告)日:2019-07-11
申请号:US16328831
申请日:2017-09-04
Applicant: HAMAMATSU PHOTONICS K.K. , NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
Inventor: Kenji YOSHIMOTO , Yukio UEDA , Etsuko OHMAE , Tetsuya MIMURA , Nobuko YOSHIZAWA , Hatsuko NASU , Hiroyuki OGURA , Harumi SAKAHARA
IPC: A61B5/00
CPC classification number: A61B5/0059 , A61B5/0091 , A61B5/1455 , A61B10/00 , A61B2562/0238
Abstract: A biological measurement device includes a probe including a contact surface that includes a plurality of light input portions that input light to a measurement target part and a plurality of light receiving portions that receive measurement light output from the measurement target part, the contact surface being pressed against the measurement target part, and a calculation unit that calculates internal information on the basis of a result of detecting the measurement light obtained for each combination of the light input portion and the light receiving portion, wherein the plurality of light input portions and the plurality of light receiving portions constitute lattices having an interval d in a first direction and a second direction orthogonal to each other on the contact surface.
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公开(公告)号:US20170119292A1
公开(公告)日:2017-05-04
申请号:US15310508
申请日:2015-04-28
Applicant: NATIONAL UNIVERSITY CORPORATION HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE , HAMAMATSU PHOTONICS K.K.
Inventor: Yukio UEDA , Etsuko YAMAKI , Harumi SAKAHARA , Hiroyuki OGURA , Hatsuko NASU , Nobuko YOSHIZAWA
IPC: A61B5/145 , A61B8/08 , A61B5/00 , A61B5/1455
CPC classification number: A61B5/14546 , A61B5/1072 , A61B5/1455 , A61B5/14551 , A61B5/4312 , A61B5/708 , A61B5/7275 , A61B5/7278 , A61B8/00 , A61B8/0825 , A61B8/085 , A61B10/00 , A61B2562/04 , G16H50/30
Abstract: A breast measurement apparatus includes a distance measurement unit measuring a distance from a skin to a light absorption portion for a measurement region of a breast which is a normal region including no tumor or an object region including a tumor, a light measurement unit measuring a hemoglobin amount in the measurement region by a light measurement method using measurement light of a predetermined wavelength, a correlation data storage unit storing normal correlation data of the distance to the light absorption portion and a normal hemoglobin amount generated based on measurement results for normal regions, and an evaluation value calculation unit calculating a property evaluation value of the tumor based on the normal hemoglobin amount, obtained from the normal correlation data and the distance to the light absorption portion in the object region, and an object hemoglobin amount in the object region.
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