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    MICROSECOND TIME-RESOLVED MASS SPECTROMETRY
    1.
    发明申请
    MICROSECOND TIME-RESOLVED MASS SPECTROMETRY 审中-公开
    MICROSECOND时间分辨质谱仪

    公开(公告)号：US20140147921A1

    公开(公告)日：2014-05-29

    申请号：US13697621

    申请日：2011-05-17

    申请人： Hao Chen ,  Zhixin Miao

    发明人： Hao Chen ,  Zhixin Miao

    IPC分类号： G01N27/68 ,  G01N33/487

    CPC分类号： G01N27/68 ,  G01N1/00 ,  G01N33/48707 ,  G01N33/6848 ,  H01J49/0445 ,  H01J49/045 ,  H01J49/145 ,  H01J49/165

    摘要： A microsecond time-resolved mass spectrometry device and method of using desorption electrospray ionization (10) was described for the kinetic study of fast reactions. The device includes a liquid jet generator (64) that is configured to emit a continuous liquid jet (50) having a length. An ambient ionization source (10) is directed toward a selected variable location along the continuous liquid jet (50) to desorb at least a portion of the continuous liquid jet (50). A mass analyzer (30) analyzes a mass-to-charge ratio of an ionized sample that is within the desorbed portion of the continuous liquid jet (50). The acquired mass spectra reflect the reaction progress in different reaction times and, therefore, may be used to derive the reaction rate.

    摘要翻译： 描述了用于快速反应的动力学研究的微秒时间分辨质谱装置和使用解吸电喷雾电离的方法（10）。 该装置包括液体喷射发生器（64），其构造成发射具有长度的连续液体射流（50）。 环境电离源（10）沿着连续液体射流（50）指向选定的可变位置以解吸至少一部分连续液体射流（50）。 质量分析器（30）分析在连续液体射流（50）的解吸附部分内的电离样品的质荷比。 所获得的质谱反映了不同反应时间的反应进程，因此可用于得到反应速率。

    METHOD AND APPARATUS OF LIQUID SAMPLE-DESORPTION ELECTROSPRAY IONIZATION-MASS SPECROMETRY (LS-DESI-MS)
    2.
    发明申请
    METHOD AND APPARATUS OF LIQUID SAMPLE-DESORPTION ELECTROSPRAY IONIZATION-MASS SPECROMETRY (LS-DESI-MS) 有权
    液体样品离子电沉积 - 质谱（LS-DESI-MS）的方法和装置

    公开(公告)号：US20100059674A1

    公开(公告)日：2010-03-11

    申请号：US12205236

    申请日：2008-09-05

    申请人： Hao Chen ,  Zhixin Miao

    发明人： Hao Chen ,  Zhixin Miao

    IPC分类号： B01D59/44

    CPC分类号： H01J49/145 ,  H01J49/045

    摘要： An apparatus and method for direct analysis of continuous-flow liquid samples by desorption electrospray ionization-mass spectrometry (DESI-MS) including a sample stage that is adapted to receive a liquid sample and a nebulizing ionizer that is configured to generate a charged, nebulized solvent and thereby desorb at least a portion of the liquid sample from the sample stage.

    摘要翻译： 一种用于通过解吸电喷雾电离质谱（DESI-MS）直接分析连续流动液体样品的装置和方法，包括适于接收液体样品的样品台和被配置为产生带电雾化的雾化离子发生器 从而从样品台解吸至少一部分液体样品。

    Method and apparatus of liquid sample-desorption electrospray ionization-mass specrometry (LS-DESI-MS)
    4.
    发明授权
    Method and apparatus of liquid sample-desorption electrospray ionization-mass specrometry (LS-DESI-MS) 有权
    液体样品 - 解吸电喷雾电离质谱法（LS-DESI-MS）的方法和装置

    公开(公告)号：US07915579B2

    公开(公告)日：2011-03-29

    申请号：US12205236

    申请日：2008-09-05

    申请人： Hao Chen ,  Zhixin Miao

    发明人： Hao Chen ,  Zhixin Miao

    IPC分类号： H01J27/00 ,  H01J49/10

    CPC分类号： H01J49/145 ,  H01J49/045

    摘要： An apparatus and method for direct analysis of continuous-flow liquid samples by desorption electrospray ionization-mass spectrometry (DESI-MS) including a sample stage that is adapted to receive a liquid sample and a nebulizing ionizer that is configured to generate a charged, nebulized solvent and thereby desorb at least a portion of the liquid sample from the sample stage.

    摘要翻译： 一种用于通过解吸电喷雾电离质谱（DESI-MS）直接分析连续流动液体样品的装置和方法，包括适于接收液体样品的样品台和被配置为产生带电雾化的雾化离子发生器 从而从样品台解吸至少一部分液体样品。

    BACKLIGHT SOURCE AND DISPLAY DEVICE
    6.
    发明公开
    BACKLIGHT SOURCE AND DISPLAY DEVICE 审中-公开

    公开(公告)号：US20240027834A1

    公开(公告)日：2024-01-25

    申请号：US17622802

    申请日：2021-12-17

    申请人： Jing Liu ,  Hongzhao Deng ,  Zhengbo Cui ,  Hao Chen

    发明人： Jing Liu ,  Hongzhao Deng ,  Zhengbo Cui ,  Hao Chen

    IPC分类号： G02F1/1335 ,  G02F1/13357 ,  G09G3/34

    CPC分类号： G02F1/133612 ,  G02F1/133603 ,  G09G3/3406 ,  G09G2320/0646

    摘要： A backlight source and a display device are provided. The display panel includes the plurality of stacked metal sub-layers and the first passivation sub-layer and the second passivation sub-layer stacked. The first passivation sub-layer is disposed between the metal layer and the second passivation layer. Material of the first passivation sub-layer includes silicon nitride. The first passivation sub-layer covers the untidy area at the ends of the molybdenum-titanium alloy thin layer to avoid from detachment of the passivation layer, and meanwhile to solve the issues of simplifying the manufacturing process of the display panel, and to avoid from oxidation of the bonding pads.

    Floor drain
    7.
    发明授权
    Floor drain 有权

    公开(公告)号：US11408163B2

    公开(公告)日：2022-08-09

    申请号：US16899621

    申请日：2020-06-12

    申请人： Wei Chen ,  Hao Chen

    发明人： Wei Chen ,  Hao Chen

    IPC分类号： E03F5/04

    摘要： A drain floor, including a drain base, a drain body including a cavity, a drain cup, a supporting frame; and a reset member. The drain cup includes a cup body, a stem, and a base. The cup body includes a through hole, and two ends of the stem are connected to the cup body and the base, respectively. The cup body is disposed in the cavity and the base is disposed out of the cavity. The space between the drain body and the drain cup forms an annular channel, and the annular channel communicates with the through hole. The annular channel includes a water inlet and a water outlet. The reset member is connected to the drain cup and is movable with respect to the drain cup to open and close the water outlet. The supporting frame connects the drain body and the reset member.

    OBJECT DETECTION USING RADAR AND MACHINE LEARNING
    9.
    发明申请
    OBJECT DETECTION USING RADAR AND MACHINE LEARNING 审中-公开

    公开(公告)号：US20170307735A1

    公开(公告)日：2017-10-26

    申请号：US15262947

    申请日：2016-09-12

    申请人： Mohsen Rohani ,  Song Zhang ,  Hao Chen

    发明人： Mohsen Rohani ,  Song Zhang ,  Hao Chen

    IPC分类号： G01S7/41 ,  G01S13/86 ,  G06N99/00

    CPC分类号： G01S7/417 ,  G01S13/865 ,  G01S13/867 ,  G01S13/89 ,  G01S17/89 ,  G06N20/00

    摘要： A method and system for using one or more radar systems for object detection based on machine learning in an environment is disclosed. A scanning radar or combination of radars mounted on a vehicle or moving object scans the environment to acquire information. The radar data may be a 3D point cloud, 2D radar image or 3D radar image. The radar data may also be combined with data from LIDAR, vision or both. A machine learning algorithm is then applied to the acquired data to detect dynamic or static objects within the environment, and identify at least one object feature comprising one of a type, location, distance, orientation, size or speed of an object.

    Tolvaptan solid dispersion and its preparation method
    10.
    发明授权
    Tolvaptan solid dispersion and its preparation method 有权
    托伐普坦固体分散体及其制备方法

    公开(公告)号：US09408915B2

    公开(公告)日：2016-08-09

    申请号：US13806173

    申请日：2011-06-02

    申请人： Yuxia Wu ,  Shujun Mao ,  Hao Chen

    发明人： Yuxia Wu ,  Shujun Mao ,  Hao Chen

    IPC分类号： A61K47/32 ,  A61K9/10 ,  A61K31/55 ,  A61K9/14 ,  A61K9/20 ,  A61K9/16

    CPC分类号： A61K47/32 ,  A61K9/10 ,  A61K9/146 ,  A61K9/1623 ,  A61K9/1652 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2077 ,  A61K31/55

    摘要： A tolvaptan solid dispersion and its preparation method are disclosed. The solid dispersion comprises tolvaptan and cross-linked polyvinylprrolidone at a weight ratio of 1:0.05-20, preferably 1:0.1-10, and more preferably 2:1. The solid dispersion can further comprise one or more water-soluble polymers, such as polyvinylprrolidone, hydroxypropyl cellulose, hydroxyethyl cellulose or methylcellulose, wherein the weight ratio of tolvaptan:the crosslinked polyvinylprrolidone:the water-soluble polymers is preferably 2:1:0.1. The solid dispersion exhibits good thermodynamic stability and solubility. The pharmaceutical composition thereof has improved release rate and bioavailability.

    摘要翻译： 披露托伐普坦固体分散体及其制备方法。 固体分散体包含托伐普坦和交联聚乙烯吡咯烷酮，重量比为1:0.05-20，优选为1：0.1-10，更优选为2：1。 固体分散体可以进一步包含一种或多种水溶性聚合物，如聚乙烯吡咯烷酮，羟丙基纤维素，羟乙基纤维素或甲基纤维素，其中托伐普坦：交联聚乙烯吡咯烷酮：水溶性聚合物的重量比优选为2:1:0.1。 固体分散体表现出良好的热力学稳定性和溶解性。 其药物组合物具有改善的释放速率和生物利用度。