公开(公告)号：US6020958A

公开(公告)日：2000-02-01

申请号：US238318

申请日：1999-01-28

申请人： Hayato Tobe ,  Kazuo Moriya ,  Hiromi Yamashita ,  Yasushi Terui

发明人： Hayato Tobe ,  Kazuo Moriya ,  Hiromi Yamashita ,  Yasushi Terui

IPC分类号： G01N21/31 ,  G01N21/74

CPC分类号： G01N21/3103

摘要： An atomic absorption spectrophotometer possessing an electrical heating unit which includes a graphite tube for atomizing a sample by heating the sample; a light emitting unit for emitting measuring light and irradiating the atomized sample with the measuring light; a spectroscope unit for diffracting the measuring light passing the electrical heating unit and selecting the required wavelength component; a detection unit for detecting the quantity of the required wavelength component selected by the spectroscope unit; an input unit to input at least one of the wavelengths of the required wavelength component and the required heating temperature of the electrical heating unit; and a control unit for controlling the above units, which comprises a shading device provided at the propagation axis of the measuring light between the electrical heating unit and the detection unit, and which possesses a light transmitting unit, for restricting the quantity of the measuring light passing the electrical heating unit, with the area of the light transmitting unit being changeable; and wherein the area of the light transmitting unit in the shading device is changed according to the set measurement conditions.

摘要翻译： 具有电加热单元的原子吸收分光光度计，其包括通过加热样品来雾化样品的石墨管; 用于发射测量光并用所述测量光照射所述雾化样品的发光单元; 用于衍射通过电加热单元的测量光并选择所需波长分量的分光器单元; 检测单元，用于检测由所述分光器单元选择的所需波长分量的量; 输入单元，用于输入所述电加热单元所需波长分量和所需加热温度的至少一个波长; 以及用于控制上述单元的控制单元，其包括设置在电加热单元和检测单元之间的测量光的传播轴上的遮光装置，并具有用于限制测量光量的光传输单元 通过电加热单元，光传输单元的区域是可变的; 并且其中遮光装置中的光发射单元的面积根据设定的测量条件而改变。

公开(公告)号：US5978082A

公开(公告)日：1999-11-02

申请号：US14069

申请日：1998-01-27

申请人： Yasushi Terui ,  Kazuo Moriya ,  Hiromi Yamashita ,  Hayato Tobe

发明人： Yasushi Terui ,  Kazuo Moriya ,  Hiromi Yamashita ,  Hayato Tobe

IPC分类号： G01N21/31 ,  G01J3/42 ,  G01N21/74

CPC分类号： G01J3/42

摘要： The object of this invention is to provide an atomic absorptiometer and a metal specimen atomic vapor generation apparatus used in the atomic absorptiometer, which enable a light absorption measurement based on the Zeeman effect highly capable of background correction and eliminate the need for the troublesome work of dismounting a magnet. For this purpose, the following configuration is employed. First, the specimen, hydrochloric acid, and sodium borohydride are delivered and mixed by the peristaltic pump 10 to produce a metallic hydride. The generated gas-liquid mixture solution is separated by the separator 12 into a specimen gas and liquids. The separated specimen gas is introduced into the heating section 30. Electricity is supplied from the power source 28 to the specimen heating section 30 where the specimen gas introduced is heated and separated into hydrogen and a specimen metal vapor to be measured. The specimen metal vapor is then introduced into the measuring section 34 arranged between magnetic poles of the magnet 32 where the metal vapor is subjected to the atomic absorptiometric analysis based on the Zeeman effect.

摘要翻译： 本发明的目的是提供一种在原子吸收光谱仪中使用的原子吸收光谱仪和金属试样原子蒸汽发生装置，其能够基于能够进行背景校正的塞曼效应的光吸收测量，并且不需要麻烦的工作 拆下磁铁 为此，采用以下配置。 首先，将试样，盐酸和硼氢化钠通过蠕动泵10输送并混合，制成金属氢化物。 所产生的气液混合溶液被分离器12分离成样品气体和液体。 将分离的试样气体引入加热部30.从电源28向被加热的试样气体加热并分离为氢的试样加热部30供给被测定的试样金属蒸气。 然后将样品金属蒸气引入到测量部分34中，该测量部分34布置在磁体32的磁极之间，金属蒸气基于塞曼效应进行原子吸收分析。

公开(公告)号：US5801827A

公开(公告)日：1998-09-01

申请号：US851291

申请日：1997-05-05

申请人： Kazuo Moriya ,  Yasushi Terui ,  Hayato Tobe ,  Yoshisada Ebata ,  Hisashi Kimoto

发明人： Kazuo Moriya ,  Yasushi Terui ,  Hayato Tobe ,  Yoshisada Ebata ,  Hisashi Kimoto

IPC分类号： G01N21/31 ,  G01N21/72

CPC分类号： G01N21/72

摘要： In an analysis device, an auxiliary gas supplied from a compressor 1 is introduced from an auxiliary gas inlet 3 via a pipe 2 to a burner through a pressure regulator 5, a pressur meter 6, a pressure switch 7 and a connecting joint 8. On the other hand, a combustible gas supplied from a gas bomb 9 is introduced from a combustible gas inlet 11 via a pipe 10 to the burner through a first electromagnetic valve 12, a pressure regulator 13, a pressure meter 14, a needle valve 15, a second electromagnetic valve 16 and a connecting joint 17 and further via a tube. An auxiliary gas use block 4, on which auxiliary gas flow controlling elements such as the pressure regulator 5, the pressure meter 6 and the pressure switch 7 are secured, is provided independent and separated from a combustible gas use block 18, on which combustible gas flow controlling elements such as the first electromagnetic valve 12, the pressure regulator 13, the pressure meter 14, the needle valve 15 and the second electromagnetic valve 16 are secured. Whereby the analysis device using chemical combustion flame having an element safety is provided in which possible danger caused by such as the gas leakage and the gas mixing between the combustible gas passage and the auxiliary gas passage is further reduced.

摘要翻译： 在分析装置中，从压缩机1供给的辅助气体通过压力调节器5，压力计6，压力开关7以及连接接头8，从辅助气体入口3经管道2引入燃烧器。 另一方面，从燃气弹9供应的可燃气体经由管道10从可燃气体入口11通过第一电磁阀12，压力调节器13，压力计14，针阀15， 第二电磁阀16和连接接头17，并且还经由管。 辅助气体使用块4，其上固定有诸如压力调节器5，压力表6和压力开关7等辅助气体流量控制元件，与可燃气体使用块18独立地分离并且与可燃气体使用块18分离， 确保了诸如第一电磁阀12，压力调节器13，压力计14，针阀15和第二电磁阀16之类的流量控制元件。 由此，提供了使用具有元件安全性的化学燃烧火焰的分析装置，其中进一步降低了由可燃气体通道和辅助气体通道之间的气体泄漏和气体混合引起的可能的危险。

公开(公告)号：US5786887A

公开(公告)日：1998-07-28

申请号：US708484

申请日：1996-09-05

申请人： Yoshisada Ebata ,  Kazuo Moriya ,  Hisashi Kimoto ,  Hayato Tobe ,  Yasushi Terui

发明人： Yoshisada Ebata ,  Kazuo Moriya ,  Hisashi Kimoto ,  Hayato Tobe ,  Yasushi Terui

IPC分类号： G01N21/31 ,  G01N21/71 ,  B01N21/00

CPC分类号： G01N21/71 ,  G01N21/3103

摘要： A light beam emitted by a hollow cathode lamp is concentrated on a central portion of an electrothermal sample atomizing apparatus by a concave mirror. The light concentrated on the central portion of the electrothermal sample atomizing apparatus is further concentrated on a central portion of a flame produced in a burner type sample atomizing apparatus by a lens. The light traveled through the burner type sample atomizing apparatus is condensed by a concave mirror, reflected by a flat mirror, and concentrated on an entrance slit of a spectroscope. Light outgoing through an exit slit of the spectroscope is detected by a photodetector.

摘要翻译： 由中空阴极灯发射的光束通过凹面镜集中在电热样品雾化装置的中心部分上。 集中在电热式雾化装置的中心部分的光进一步集中在通过透镜在燃烧器型样品雾化装置中产生的火焰的中心部分上。 通过燃烧器型样品雾化装置行进的光由凹面镜冷凝，由平面镜反射，并集中在分光镜的入口狭缝上。 通过光电检测器检测出通过光谱仪的出口狭缝的光。

公开(公告)号：US5822059A

公开(公告)日：1998-10-13

申请号：US633234

申请日：1996-04-16

申请人： Hayato Tobe ,  Kazuo Moriya ,  Yoshisada Ebata ,  Yasushi Terui

发明人： Hayato Tobe ,  Kazuo Moriya ,  Yoshisada Ebata ,  Yasushi Terui

IPC分类号： G01N21/31 ,  G01N21/74 ,  G01J3/30

CPC分类号： G01N21/74

摘要： The invention intends to provide an atomic absorption spectrophotometer which can establish a uniform heat distribution during heating of a sample and can improve analysis accuracy and analyzing efficiency. For this purpose, a graphite tube type cuvette mounted in a graphite atomizer furnace for an atomic absorption spectrophotometer comprises a large-diameter portion for retaining a sample in place, a small-diameter portion connected to the large-diameter portion and having a smaller diameter than the large-diameter portion, and a step portion for demarcating between the large-diameter portion and the small-diameter portion. The graphite tube type cuvette is formed such that its cross-sectional area in a plane perpendicular to the direction of passage of an electric current supplied to the cuvette is the same in any of the large-diameter portion, the small-diameter portion and the step portion. The amount of resistance heat is thereby also the same in any portions.

摘要翻译： 本发明旨在提供一种原子吸收分光光度计，可在样品加热期间建立均匀的热分布，并可提高分析精度和分析效率。 为此，安装在用于原子吸收分光光度计的石墨雾化炉中的石墨管型比色皿包括用于将样品保持在适当位置的大直径部分，与大直径部分连接并具有较小直径的小直径部分 和大直径部分之间划分的台阶部分，以及用于在大直径部分和小直径部分之间划定的台阶部分。 石墨管型比色皿形成为使得其在垂直于供给到比色杯的电流的通过方向的平面中的横截面面积在大直径部分，小直径部分和 步骤部分。 因此，电阻热的量在任何部分也是相同的。

公开(公告)号：US20120154190A1

公开(公告)日：2012-06-21

申请号：US13387122

申请日：2010-08-30

申请人： Fujio Oonishi ,  Yasushi Terui ,  Tsukasa Shishika

发明人： Fujio Oonishi ,  Yasushi Terui ,  Tsukasa Shishika

IPC分类号： H03M1/00

CPC分类号： H01J49/025

摘要： A signal processing device includes amplifiers that are capable of amplifying detected signals using amplification factors that are different from each other; A/D converters that sample plural signals amplified by the amplifiers using the different amplification factors and output from the amplifiers; calculators that perform, on the basis of the amplification factors of the plural amplifiers, calculation on plural data pieces converted by the A/D converters; and a selector that selects one or more of output data pieces from among plural data pieces output from the calculators.

摘要翻译： 信号处理装置包括能够使用彼此不同的放大因子来放大检测信号的放大器; A / D转换器，其采用不同的放大因子对放大器放大的多个信号进行采样并从放大器输出; 基于多个放大器的放大系数执行由A / D转换器转换的多个数据片的计算的计算器; 以及从计算器输出的多个数据中选择一个或多个输出数据段的选择器。

公开(公告)号：US20090179148A1

公开(公告)日：2009-07-16

申请号：US12350328

申请日：2009-01-08

申请人： Hiroyuki Yasuda ,  Yasushi Terui ,  Shinji Nagai ,  Tetsuya Nishida

发明人： Hiroyuki Yasuda ,  Yasushi Terui ,  Shinji Nagai ,  Tetsuya Nishida

IPC分类号： B01D59/44 ,  H01J49/00

CPC分类号： H01J49/004 ,  H01J49/063

摘要： Performing an MS3 with a tandem mass spectrometer causes problems of increase in size of the device and of increase in cost. Likewise, a plural number of times MS/MS analyses are even more difficult. An electrode to create a harmonic potential is disposed in a collision cell, and fragment ions produced by the first-time collision induced dissociation are accumulated in the harmonic potential. Target ions of the subsequent stage are let out, by means of an axial resonance excitation, selectively from the accumulated ions. The ions are excited in the axial direction to have a potential exceeding the harmonic potential. Thereby, the second-time collision induced dissociation is performed by means of a potential difference provided at the subsequent stage. In addition, an operation to return the ions back to the harmonic potential enables a plural number of times MS/MS analyses to be performed.

摘要翻译： 使用串联质谱仪进行MS3会导致设备尺寸增加和成本增加的问题。 同样，多次MS / MS分析更加困难。 用于产生谐波电位的电极设置在碰撞室中，并且由第一次碰撞引起的解离产生的碎片离子累积在谐波电位中。 选择性地从累积的离子中排出后续阶段的目标离子，借助于轴向共振激发。 离子在轴向上被激发以具有超过谐波电位的电位。 因此，通过在后续阶段提供的电位差来执行第二次碰撞诱导解离。 此外，使离子返回到谐波电位的操作能够进行多次MS / MS分析。

公开(公告)号：US07544930B2

公开(公告)日：2009-06-09

申请号：US11624248

申请日：2007-01-18

申请人： Kiyomi Yoshinari ,  Yasushi Terui ,  Toshiyuki Yokosuka ,  Kinya Kobayashi ,  Atsumu Hirabayashi

发明人： Kiyomi Yoshinari ,  Yasushi Terui ,  Toshiyuki Yokosuka ,  Kinya Kobayashi ,  Atsumu Hirabayashi

IPC分类号： H01J49/00

CPC分类号： H01J49/02 ,  H01J49/004

摘要： The present invention provides a tandem type mass analysis system capable of carrying out the differential analysis with high efficiency by the tandem type mass analysis. A predetermined number of m/z regions are set up for carrying out the mass analysis with the all ions included therein being dissociated collectively for each m/z region so as to obtain measurement MS2 data. By comparing the measurement MS2 data with reference MS2 data stored in a reference data base, a difference thereof is detected. For the m/z region with a differential component detected, the mass analysis is carried out collectively without dissociation for the all ions included therein so as to obtain measurement MS1 data. By comparing the measurement MS1 data with the reference MS1 data, a difference thereof is detected. From the difference thereof, a parent ion considered to be the differential component factor is presumed for carrying out the mass analysis with the same being dissociated.

摘要翻译： 本发明提供一种能够通过串联型质量分析以高效率进行差示分析的串联式质量分析系统。 建立预定数量的m / z区域以进行质量分析，其中包含的全部离子为每个m / z区域共同解离，以获得测量MS2数据。 通过将测量MS2数据与参考数据库中存储的参考MS2数据进行比较，检测其差异。 对于检测到差分成分的m / z区域，对于其中包含的所有离子，不分离地进行质量分析，以获得测量MS1数据。 通过将测量MS1数据与参考MS1数据进行比较，检测其差异。 从它们的差异来看，推测认为是差分成分因子的母离子用于进行相同解离的质量分析。

公开(公告)号：US20080315082A1

公开(公告)日：2008-12-25

申请号：US12078680

申请日：2008-04-03

申请人： Izumi Ogata ,  Yasushi Terui

发明人： Izumi Ogata ,  Yasushi Terui

IPC分类号： B01D59/44

CPC分类号： H01J49/004

摘要： A tandem mass spectrometer comprising an ion source for ionizing a sample, an ion trap section for carrying out collision induced dissociation of the target ions thereby to produce fragment ions, a multi electrode collision section for conducting collision induced dissociation of fragment ions discharged from the ion trap section, a mass spectrometer section for conducting mass spectrometric analysis of the converged fragment ions. After the target ions selected by the ion trap section are subjected to collision induced dissociation, specific fragment ions among the fragment ions are selected and transferred to the multi electrode collision section thereby to carry out collision induced dissociation therein.

摘要翻译： 一种串联质谱仪，包括用于离子化样品的离子源，用于进行目标离子的碰撞诱导解离从而产生碎片离子的离子捕获部分，用于进行从离子排出的碎片离子的碰撞诱导解离的多电极碰撞部分 捕获部分，用于进行会聚碎片离子的质谱分析的质谱仪部分。 在由离子阱部分选择的目标离子经受碰撞诱导解离之后，选择碎片离子之间的特定碎片离子并将其转移到多电极碰撞部分，从而在其中进行碰撞诱导解离。

公开(公告)号：US20050279926A1

公开(公告)日：2005-12-22

申请号：US11149263

申请日：2005-06-10

申请人： Yasushi Terui ,  Toyoharu Okumoto ,  Tsukasa Shishika ,  Shinji Nagai ,  Masaru Tomioka

发明人： Yasushi Terui ,  Toyoharu Okumoto ,  Tsukasa Shishika ,  Shinji Nagai ,  Masaru Tomioka

IPC分类号： G01N27/62 ,  B01D59/44 ,  H01J49/40 ,  H01J49/42

CPC分类号： H01J49/424 ,  H01J49/0009 ,  H01J49/0031 ,  H01J49/004 ,  H01J49/40 ,  H01J49/427

摘要： An “ion trap-TOF/MS” capable of calibrating the observed mass for each of an ion trap and a TOF. In the ion trap-TOF/MS, sample ions having known mass numbers and ionized by an ion source are trapped within an ion trap. Auxiliary AC voltages having a frequency component ω are applied to the end cap electrodes of the ion trap to expel unwanted ions out of the ion trap. A measurement process is carried out by applying DC voltages to the ring electrode and the end cap electrodes to expel an ion remaining within the ion trap, and measuring the mass number of the expelled ion by the time-of-flight mass spectrometer. The measurement process is repeated while changing the frequency component ω, and the ion signal intensity measured by the time-of-flight mass spectrometer is compared with a previously stored threshold, thereby making calibration of the frequency component ω for the ion having the known mass number. Thus, the calibrating of the observed mass can be realized for each of the ion trap and the TOF.

摘要翻译： 能够校准每个离子阱和TOF的观察质量的“离子阱TOF / MS”。 在离子阱TOF / MS中，已知质量数和离子源电离的样品离子被捕获在离子阱内。 具有频率分量ω的辅助AC电压被施加到离子阱的端盖电极以将不需要的离子排出离子阱。 通过向环形电极和端盖电极施加直流电压以排出留在离子阱内的离子，并且通过飞行时间质谱仪测量排出的离子的质量数来进行测量处理。 在改变频率分量ω时重复测量过程，并将通过飞行时间质谱仪测量的离子信号强度与先前存储的阈值进行比较，从而对具有已知质量的离子进行频率分量ω的校准 数。 因此，可以为每个离子阱和TOF实现观察质量的校准。