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    SYSTEMS AND METHODS FOR IMAGE PROCESSING TO DETERMINE BLOOD FLOW
    1.
    发明申请
    SYSTEMS AND METHODS FOR IMAGE PROCESSING TO DETERMINE BLOOD FLOW 有权

    公开(公告)号：US20210358635A1

    公开(公告)日：2021-11-18

    申请号：US17388655

    申请日：2021-07-29

    申请人： HeartFlow, Inc.

    发明人： Sethuraman Sankaran ,  Leo J. Grady ,  Charles A. Taylor

    IPC分类号： G16H50/50 ,  A61B6/00 ,  A61B5/02 ,  A61B5/026 ,  G06T7/00 ,  A61B5/00 ,  A61B5/055 ,  A61B6/03

    摘要： Embodiments include systems and methods for determining cardiovascular information for a patient. A method includes receiving patient-specific data regarding a geometry of the patient's vasculature; creating an anatomic model representing at least a portion of the patient's vasculature based on the patient-specific data; and creating a computational model of a blood flow characteristic based on the anatomic model. The method also includes identifying one or more of an uncertain parameter, an uncertain clinical variable, and an uncertain geometry; modifying a probability model based on one or more of the identified uncertain parameter, uncertain clinical variable, or uncertain geometry; determining a blood flow characteristic within the patient's vasculature based on the anatomic model and the computational model of the blood flow characteristic of the patient's vasculature; and calculating, based on the probability model and the determined blood flow characteristic, a sensitivity of the determined fractional flow reserve to one or more of the identified uncertain parameter, uncertain clinical variable, or uncertain geometry.

    Systems and methods for vascular diagnosis using blood flow magnitude and/or direction
    2.
    发明授权
    Systems and methods for vascular diagnosis using blood flow magnitude and/or direction 有权

    公开(公告)号：US10987010B2

    公开(公告)日：2021-04-27

    申请号：US14691105

    申请日：2015-04-20

    申请人： HeartFlow, Inc.

    发明人： Leo J. Grady ,  Charles A. Taylor

    IPC分类号： A61B5/026 ,  A61B5/00 ,  A61B8/06 ,  A61B8/08 ,  G16H50/50 ,  G16H50/20 ,  A61B5/02

    摘要： Systems and methods are disclosed for diagnosing and treatment planning for vascular steal syndromes and retrograde flow. One method includes receiving a reference blood flow direction at a location in a reference vasculature; determining a patient-related blood flow direction at a location in a patient's vasculature corresponding to the location in the reference vasculature; determining a difference in direction, between the reference blood flow direction of the reference vasculature and the patient-related blood flow direction of the patient's vasculature; and generating a representation of the location in the patient's vasculature associated with the difference in direction between the reference blood flow direction and the patient-related blood flow direction, or generating a treatment recommendation for the patient's vasculature based on the difference in direction between the reference blood flow direction and the patient-related blood flow direction.

    Systems and methods for simulation of occluded arteries and optimization of occlusion-based treatments
    4.
    发明授权
    Systems and methods for simulation of occluded arteries and optimization of occlusion-based treatments 有权
    闭塞动脉模拟的系统和方法以及基于闭塞治疗的优化

    公开(公告)号：US09594876B2

    公开(公告)日：2017-03-14

    申请号：US14598050

    申请日：2015-01-15

    申请人： HeartFlow, Inc.

    发明人： Sethuraman Sankaran ,  Leo J. Grady ,  Charles A. Taylor ,  Christopher K. Zarins

    IPC分类号： G06F19/00 ,  G06F19/10 ,  A61B5/02 ,  G06K9/36

    CPC分类号： G16H50/50 ,  G06F17/18 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3481

    摘要： Systems and methods are disclosed for simulation of occluded arteries and/or optimization of occlusion-based treatments. One method includes obtaining a patient-specific anatomic model of a patient's vasculature; obtaining an initial computational model of blood flow through the patient's vasculature based on the patient-specific anatomic model; obtaining a post-treatment computational model by modifying portions of the initial computational model based on an occlusion-based treatment; generating a pre-treatment blood flow characteristic using the initial computational model or computing a post-treatment blood flow using the post-treatment computational model; and outputting a representation of the pre-treatment blood flow characteristic or the post-treatment blood flow characteristic.

    摘要翻译： 公开了用于模拟闭塞动脉和/或基于阻塞的治疗的优化的系统和方法。 一种方法包括获得患者脉管系统的患者特异性解剖模型; 基于患者特异性解剖模型获得通过患者脉管系统的血流的初始计算模型; 通过基于基于遮挡的处理修改初始计算模型的部分来获得后处理计算模型; 使用初始计算模型产生预处理血液流动特性或使用后处理计算模型计算后处理血流量; 并输出预处理血流特性或后处理血流特性的表示。