利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

8 条记录 (耗时 0.024 秒)

    Production of quaternary ammonium salt of hydroxycarboxylic acid and quaternary ammonium salt of inorganic acid
    5.
    发明授权
    Production of quaternary ammonium salt of hydroxycarboxylic acid and quaternary ammonium salt of inorganic acid 失效
    生产羟基羧酸季铵盐和无机酸季铵盐

    公开(公告)号：US06967258B2

    公开(公告)日：2005-11-22

    申请号：US10840359

    申请日：2004-05-07

    申请人： Yutaka Kanbara ,  Yasushi Higuchi ,  Tomoo Tsujimoto ,  Genki Nogami

    发明人： Yutaka Kanbara ,  Yasushi Higuchi ,  Tomoo Tsujimoto ,  Genki Nogami

    IPC分类号： C07C211/63 ,  C07C209/20 ,  C07C209/00

    CPC分类号： C07C209/20 ,  C07C211/63

    摘要： A quaternary ammonium hydroxycarboxylate is produced by quaternizing a tertiary amine with a hydroxycarboxylic ester represented by the following Formula 1: wherein R1 to R3 are as defined in the disclosure. By using only one tertiary amine having at least one substituent different from R1 of the ester moiety of the hydroxycarboxylic ester and by controlling the reaction conditions, a mixture of quaternary ammonium hydroxycarboxylates having different quaternary ammonium ions is produced. By reacting an inorganic acid with the quaternary ammonium hydroxycarboxylate or its mixture, a quaternary ammonium salt of inorganic acid or its mixture is produced.

    摘要翻译： 季铵羟基羧酸盐是通过用下列通式1表示的羟基羧酸季铵化叔胺制备的：其中R 1至R 3如本公开所定义。 通过仅使用一种具有至少一个不同于羟基羧酸酯的酯部分的R 1的取代基的叔胺并通过控制反应条件，产生具有不同季铵离子的季铵羟基羧酸盐的混合物 。 通过使无机酸与羟基羧酸季铵盐或其混合物反应，生成无机酸的季铵盐或其混合物。

    Process for Producing Carnitinamide
    6.
    发明申请
    Process for Producing Carnitinamide 失效
    生产肉毒杆菌的方法

    公开(公告)号：US20090143616A1

    公开(公告)日：2009-06-04

    申请号：US11992831

    申请日：2006-08-24

    申请人： Genki Nogami ,  Hideo Ikarashi ,  Shinyo Gayama

    发明人： Genki Nogami ,  Hideo Ikarashi ,  Shinyo Gayama

    IPC分类号： C07C227/02

    CPC分类号： B01J23/34 ,  B01J23/002 ,  B01J2523/00 ,  C07C231/06 ,  B01J2523/13 ,  B01J2523/55 ,  B01J2523/72 ,  B01J2523/54 ,  B01J2523/43 ,  C07C237/06

    摘要： A process for producing carnitinamide which is an intermediate for production of L-carnitine is provided, which can hydrate carnitine nitrile to form carnitinamide with high selectivity, whereby highly-purified carnitinamide excellent as a substrate for stereoselective hydrolysis by optical resolution or a microorganism is produced in high yield. The process comprises hydrating carnitine nitrile to form carnitinamide using a catalyst containing a manganese oxide, and thus carnitinamide substantially free from by-produced carnitine is produced in high yield, so that carnitinamide of extremely high purity can be obtained through simple and easy crystallization operation.

    摘要翻译： 提供了生产左旋肉碱的中间体生产肉碱酰胺的方法，其可以以高选择性水合肉碱腈以形成肉碱酰胺，由此产生作为通过光学拆分或微生物进行立体选择性水解的底物的高度纯化的肉碱胺 以高产量。 该方法包括使用含有氧化锰的催化剂水化肉碱腈以形成肉毒碱，从而以高产率生产基本上不含副产肉碱的肉毒碱，从而可以通过简单且容易的结晶操作获得极高纯度的肉毒碱。

    Production of quaternary ammonium salt of hydroxycarboxylic acid and quarternary ammonium salt of inorganic acid
    7.
    发明授权
    Production of quaternary ammonium salt of hydroxycarboxylic acid and quarternary ammonium salt of inorganic acid 失效
    生产羟基羧酸季铵盐和无机酸季铵盐

    公开(公告)号：US06784317B2

    公开(公告)日：2004-08-31

    申请号：US10125371

    申请日：2002-04-19

    申请人： Yutaka Kanbara ,  Yasushi Higuchi ,  Tomoo Tsujimoto ,  Genki Nogami

    发明人： Yutaka Kanbara ,  Yasushi Higuchi ,  Tomoo Tsujimoto ,  Genki Nogami

    IPC分类号： C07C21162

    CPC分类号： C07C209/20 ,  C07C211/63

    摘要： A quaternary ammonium hydroxycarboxylate is produced by quaternizing a tertiary amine with a hydroxycarboxylic ester represented by the following Formula 1: wherein R1 to R3 are as defined in the disclosure. By using only one tertiary amine having at least one substituent different from R1 of the ester moiety of the hydroxycarboxylic ester and by controlling the reaction conditions, a mixture of quaternary ammonium hydroxycarboxylates having different quaternary ammonium ions is produced. By reacting an inorganic acid with the quaternary ammonium hydroxycarboxylate or its mixture, a quaternary ammonium salt of inorganic acid or its mixture is produced.

    摘要翻译： 通过用下列通式1表示的羟基羧酸季铵化叔胺来制备羟基羧酸季铵盐：其中R 1至R 3如本公开所定义。 通过仅使用一种具有至少一个与羟基羧酸酯的酯部分的R 1不同的取代基的叔胺，并且通过控制反应条件，产生具有不同季铵离子的季铵羟基羧酸盐的混合物。 通过使无机酸与羟基羧酸季铵盐或其混合物反应，生成无机酸的季铵盐或其混合物。

    Process for producing carnitinamide
    8.
    发明授权
    Process for producing carnitinamide 失效
    肉碱生产方法

    公开(公告)号：US07714166B2

    公开(公告)日：2010-05-11

    申请号：US11992831

    申请日：2006-08-24

    申请人： Genki Nogami ,  Hideo Ikarashi ,  Shinyo Gayama

    发明人： Genki Nogami ,  Hideo Ikarashi ,  Shinyo Gayama

    IPC分类号： C07C231/00

    CPC分类号： B01J23/34 ,  B01J23/002 ,  B01J2523/00 ,  C07C231/06 ,  B01J2523/13 ,  B01J2523/55 ,  B01J2523/72 ,  B01J2523/54 ,  B01J2523/43 ,  C07C237/06

    摘要： A process for producing carnitinamide which is an intermediate for production of L-carnitine is provided, which can hydrate carnitine nitrile to form carnitinamide with high selectivity, whereby highly-purified carnitinamide excellent as a substrate for stereoselective hydrolysis by optical resolution or a microorganism is produced in high yield. The process comprises hydrating carnitine nitrile to form carnitinamide using a catalyst containing a manganese oxide, and thus carnitinamide substantially free from by-produced carnitine is produced in high yield, so that carnitinamide of extremely high purity can be obtained through simple and easy crystallization operation.

    摘要翻译： 提供了生产左旋肉碱的中间体生产肉碱酰胺的方法，其可以以高选择性水合肉碱腈以形成肉碱酰胺，由此产生作为通过光学拆分或微生物进行立体选择性水解的底物的高度纯化的肉碱胺 以高产量。 该方法包括使用含有氧化锰的催化剂水化肉碱腈以形成肉毒碱，从而以高产率生产基本上不含副产肉碱的肉毒碱，从而可以通过简单且容易的结晶操作获得极高纯度的肉毒碱。