公开(公告)号：US4212062A

公开(公告)日：1980-07-08

申请号：US919627

申请日：1978-06-27

申请人： Hideki Kohno ,  Hidemi Shiono ,  Chitose Nakaya ,  Kensuke Sekihara ,  Teruichi Tomura ,  Shinji Yamamoto ,  Takayuki Hayakawa ,  Isao Horiba ,  Shigenobu Yanaka

发明人： Hideki Kohno ,  Hidemi Shiono ,  Chitose Nakaya ,  Kensuke Sekihara ,  Teruichi Tomura ,  Shinji Yamamoto ,  Takayuki Hayakawa ,  Isao Horiba ,  Shigenobu Yanaka

IPC分类号： G01N23/04 ,  A61B6/03 ,  G06Q50/22 ,  G06Q50/24 ,  G06T11/00 ,  G06F15/34

CPC分类号： A61B6/032 ,  G06T11/006 ,  Y10S378/901

摘要： A tomographic imaging system is disclosed in which the quantity of absorption or transmittance of a transmissive radiation by or through a certain tomographic cross-section of an object under consideration is detected and the distribution of radiation absorption or transmittance in the cross-section is reconstructed through a convolution operation. A weighting function used in the convolution operation is prepared with a predetermined one of its positive orders the value of which is an integration of the weighting function from the predetermined positive order to positive infinity and a predetermined one of its negative orders the value of which is in integration of the weighting function from the predetermined negative order to negative infinity.

摘要翻译： 公开了一种断层图像成像系统，其中检测由所考虑的物体的特定断层摄影横截面或通过所考虑的物体的某些断层摄影横截面的透射辐射的吸收或透射率，并且通过以下方式重建横截面中的辐射吸收或透射率的分布： 卷积运算 在卷积运算中使用的加权函数以其正值中的预定的一个准备，该值的正值为加权函数从预定的正阶数到正无穷大的积分，以及负值的预定值，其值是 将加权函数从预定的负数整合到负无穷大。

公开(公告)号：US4211926A

公开(公告)日：1980-07-08

申请号：US901241

申请日：1978-04-28

申请人： Chitose Nakaya ,  Hideki Kohno ,  Hidemi Shiono ,  Kensuke Sekihara ,  Shinji Yamamoto ,  Teruichi Tomura ,  Takayuki Hayakawa

发明人： Chitose Nakaya ,  Hideki Kohno ,  Hidemi Shiono ,  Kensuke Sekihara ,  Shinji Yamamoto ,  Teruichi Tomura ,  Takayuki Hayakawa

IPC分类号： G01N23/04 ,  A61B6/03 ,  A61B8/00 ,  G06Q50/22 ,  G06Q50/24 ,  G06T11/00 ,  G03B41/16

CPC分类号： A61B6/032

摘要： In a system in which the tomographic image of an object under investigation is produced on the basis of the amount of absorption of radiation by the object when a source of radiation and a plurality of radiation sensitive detectors with the object interposed therebetween are rotated around the object, the output signal from at least one of the plural detectors is used to correct the radiation absorption amount. Another selected one of the plural detectors may be used for checking whether the object is positioned within a useful detection view.

摘要翻译： 在这样一个系统中，在被照明物体插入其间的物体的多个辐射敏感探测器围绕物体旋转时，基于物体的辐射吸收量产生被研究对象的断层图像 使用来自多个检测器中的至少一个的输出信号来校正辐射吸收量。 多个检测器中的另一选择的一个可以用于检查对象是否位于有用的检测视图内。

公开(公告)号：US4326252A

公开(公告)日：1982-04-20

申请号：US101769

申请日：1979-12-10

申请人： Hideki Kohno ,  Hidemi Shiono ,  Shinji Yamamoto

发明人： Hideki Kohno ,  Hidemi Shiono ,  Shinji Yamamoto

IPC分类号： A61B6/03 ,  G06T11/00 ,  G01N23/00

CPC分类号： G06T11/006 ,  A61B6/032 ,  G06T2211/421 ,  Y10S378/901

摘要： A method is disclosed in which projection images of a certain cross-section of an object are produced through irradiation from various directions to the cross-section, and a three-dimensional image of the cross-section is reconstructed from the projection images. A convolution integral operation is performed on the projection images by means of a weighting function obtained from a function whose second differentiation is positive in at least a predetermined range of a spacial frequency domain and which has a positive first-differential coefficient at a point where the spacial frequency is equal to zero.

摘要翻译： 公开了一种方法，其中通过从各个方向到横截面的照射产生物体的某个横截面的投影图像，并且从投影图像重建横截面的三维图像。 通过从在空间频域的至少预定范围内的第二微分为正的函数获得的加权函数对投影图像进行卷积积分运算，并且在第一微分系数在 空间频率等于零。

公开(公告)号：US4082457A

公开(公告)日：1978-04-04

申请号：US664567

申请日：1976-03-08

申请人： Hideki Kohno ,  Akihide Hashizume ,  Shinji Yamamoto

发明人： Hideki Kohno ,  Akihide Hashizume ,  Shinji Yamamoto

IPC分类号： G01N33/48 ,  G01N15/14 ,  G01N33/16

CPC分类号： G01N15/1468 ,  G01N15/1475

摘要： A leukocyte detector comprises a first and a second filter means adapted to select color components with different wave lengths, or green and blue color components, respectively, from the microscopic image of a stained blood smear, a first and a second opto-electric converter means for converting the transmitted light from said first and second filter means into corresponding electrical signals, a subtractor for subtracting the outputs from said first and second opto-electric converter means, and a comparator which compares the output of said subtractor with the predetermined threshold limit value.

公开(公告)号：US4472683A

公开(公告)日：1984-09-18

申请号：US420303

申请日：1982-09-20

申请人： Kensuke Sekihara ,  Etsuji Yamamoto ,  Hideki Kohno ,  Shinji Yamamoto

发明人： Kensuke Sekihara ,  Etsuji Yamamoto ,  Hideki Kohno ,  Shinji Yamamoto

IPC分类号： A61B10/00 ,  A61B5/055 ,  G01R33/48 ,  G01R33/54 ,  G01R33/08

CPC分类号： G01R33/4833

摘要： An imaging apparatus using nuclear magnetic resonance is disclosed in which both an image corresponding to the projection of a nuclear spin distribution in a to-be-inspected object on a two-dimensional plane and a display mark indicating a desired measuring position are displayed on a display face of a display device such as a CRT display, the display mark is freely moved on the display face to be set at a desired position on the display face, and magnetic field generating means for generating a static magnetic field, linear gradient field, or radio frequency magnetic field is controlled on the basis of the desired position of the display mark to obtain an image of that cross section of the object which is located at a position indicated by the display mark.

摘要翻译： 公开了一种使用核磁共振的成像装置，其中在二维平面上的被检查物体中的核自旋分布的投影和指示期望的测量位置的显示标记的图像都显示在 CRT显示器等显示装置的显示面，在显示面上自由移动显示标记，将其设定在显示面上的期望位置，产生静磁场，线性梯度场， 或者基于显示标记的期望位置来控制射频磁场，以获得位于由显示标记指示的位置处的对象的该横截面的图像。

公开(公告)号：US4558425A

公开(公告)日：1985-12-10

申请号：US413821

申请日：1982-09-01

申请人： Etsuji Yamamoto ,  Kensuke Sekihara ,  Hideki Kohno ,  Shinji Yamamoto

发明人： Etsuji Yamamoto ,  Kensuke Sekihara ,  Hideki Kohno ,  Shinji Yamamoto

IPC分类号： A61B10/00 ,  A61B5/055 ,  A61B5/107 ,  G01R33/28 ,  G01R33/38 ,  G01R33/48 ,  G01R33/58 ,  G01N15/00

CPC分类号： G01R33/381 ,  A61B5/1077 ,  G01R33/28 ,  G01R33/58

摘要： In an imaging apparatus using nuclear magnetic resonance which includes apparatus for generating a static magnetic field, a linear gradient magnetic field and a radio frequency magnetic field, respectively, signal detection device for detecting the nuclear magnetic resonant signal from an object to be inspected, a computer for calculating from the detection signal an image and output device for displaying the result of calculation by the computer, the improvement wherein the size of the object to be inspected is detected by use of ultrasonic wave or light beams and a signal indicative of the detected size of the object is applied to the linear gradient magnetic field generation apparatus so as to control the intensity of the linear gradient magnetic field.

摘要翻译： 在使用核磁共振的成像装置中，分别包括用于产生静磁场的装置，线性梯度磁场和射频磁场，用于检测来自被检体的核磁共振信号的信号检测装置， 用于从检测信号计算用于显示计算机的计算结果的图像和输出装置的计算机，其中通过使用超声波或光束来检测要检查的对象的大小，以及指示检测到的信号的信号 物体的大小被施加到线性梯度磁场产生装置，以便控制线性梯度磁场的强度。

公开(公告)号：US3969024A

公开(公告)日：1976-07-13

申请号：US604185

申请日：1975-08-13

申请人： Akihide Hashizume ,  Hideki Kohno ,  Shinji Yamamoto

发明人： Akihide Hashizume ,  Hideki Kohno ,  Shinji Yamamoto

IPC分类号： G01N33/48 ,  G01N15/14 ,  G06K9/00 ,  G06T1/00 ,  G01N33/16

CPC分类号： G01N15/1468 ,  G06K9/00127

摘要： A signal separation system is used to discriminate cytoplasm of white blood cells from a sample of white blood. The signal separation system includes a light source generating light passed through a blood sample, a light separator for separating green and blue light beams from the light passed through the sample, first and second photoelectric converters for changing the green and the blue light beams to first and second electric signals, a signal treatment circuit which converts the first and the second electric signals to binary signals with respect to certain threshold levels and then forms a separation signal from the binary signals, and the gate circuit which separates the signal component of the white blood cells from the sample with the function of the separation signal.

摘要翻译： 信号分离系统用于鉴别白细胞的细胞质与白血样品。 信号分离系统包括产生通过血液样本的光的光源，用于从通过样本的光中分离绿色和蓝色光束的光分离器，用于将绿色和蓝色光束改变为第一和第二光电转换器的第一和第二光电转换器 和第二电信号，信号处理电路，其将第一和第二电信号相对于某个阈值电平转换为二进制信号，然后形成来自二进制信号的分离信号;以及门电路，其分离白色的信号分量 来自样品的血细胞具有分离信号的功能。

公开(公告)号：US09055753B2

公开(公告)日：2015-06-16

申请号：US11996649

申请日：2006-07-28

申请人： Yasushi Shioya ,  Yoshinobu Hayakawa ,  Shinji Yamamoto ,  Yoshikazu Ogura

发明人： Yasushi Shioya ,  Yoshinobu Hayakawa ,  Shinji Yamamoto ,  Yoshikazu Ogura

IPC分类号： A23F5/18 ,  A23F5/24 ,  A61K36/74

CPC分类号： A23F5/243 ,  A23F5/185 ,  A23V2002/00 ,  A61K36/74 ,  A23V2250/028 ,  A23V2200/326

摘要： Disclosed is a container-packed black coffee beverage which has an excellent hypertension ameliorating effect and can be ingested in an ordinary manner. A container-packed black coffee satisfying the following requirements (A) to (C): (A) a chlorogenic acid: 0.01 to 1% by mass; (B) hydroxyhydroquinone: 0.1% by mass or less relative to the mass of the chlorogenic acid; and (C) the chlorogenic acid/a coffee solid content ≧0.025 (by mass).

摘要翻译： 公开了一种容器包装的黑咖啡饮料，其具有优异的高血压改善效果并且可以以普通方式摄取。 满足以下要求（A）至（C）的容器包装的黑咖啡：（A）绿原酸：0.01〜1质量％ （B）羟基氢醌：相对于绿原酸的质量为0.1质量％以下; 和（C）绿原酸/咖啡固体成分≥0.025（质量百分比）。

公开(公告)号：US09017669B2

公开(公告)日：2015-04-28

申请号：US13519127

申请日：2009-12-28

申请人： Yasuhiro Shiba ,  Hiroki Yoshioka ,  Shinji Yamamoto ,  Aiko Kudo ,  Ryuji Ohsawa ,  Pohsing Ng ,  Yusuke Nakamura ,  Keigo Endo

发明人： Yasuhiro Shiba ,  Hiroki Yoshioka ,  Shinji Yamamoto ,  Aiko Kudo ,  Ryuji Ohsawa ,  Pohsing Ng ,  Yusuke Nakamura ,  Keigo Endo

IPC分类号： C07K16/00 ,  C07K16/46 ,  C07K16/28 ,  A61K39/395 ,  G01N33/53 ,  A61K51/10 ,  C07K16/06 ,  G01N33/574 ,  A61K39/00

CPC分类号： C07K16/28 ,  A61K51/1027 ,  A61K2039/505 ,  C07K16/065 ,  C07K2317/41 ,  C07K2317/56 ,  G01N33/574 ,  G01N2333/705

摘要： The present invention relates to anti-CDH3 antibodies, which can be labeled with a radioisotope. Moreover, the present invention provides methods and pharmaceutical compositions that comprise an anti-CDH3 antibody as an active ingredient. Since CDH3 is strongly expressed in pancreatic, lung, colon, prostate, breast, gastric or liver cancer cells, the present invention is useful in pancreatic, lung, colon, prostate, breast, gastric or liver cancer therapies.

摘要翻译： 本发明涉及可用放射性同位素标记的抗CDH3抗体。 此外，本发明提供包含抗CDH3抗体作为活性成分的方法和药物组合物。 由于CDH3在胰腺，肺癌，结肠癌，前列腺癌，乳腺癌，胃癌或肝癌细胞中强烈表达，本发明可用于胰腺，肺癌，结肠癌，前列腺癌，乳腺癌，胃癌或肝癌的治疗。

公开(公告)号：US08831446B2

公开(公告)日：2014-09-09

申请号：US13017275

申请日：2011-01-31

申请人： Tadashi Matsumoto ,  Sumitoshi Sootome ,  Yasumi Yoshida ,  Shinji Yamamoto ,  Takashi Hiratsuka ,  Toshihiro Fukasaka

发明人： Tadashi Matsumoto ,  Sumitoshi Sootome ,  Yasumi Yoshida ,  Shinji Yamamoto ,  Takashi Hiratsuka ,  Toshihiro Fukasaka

IPC分类号： G03G15/00 ,  G03G15/01 ,  G03G15/02

CPC分类号： G03G15/0131 ,  G03G15/1615 ,  G03G15/5054 ,  G03G15/5058 ,  G03G2215/00059 ,  G03G2215/00156 ,  G03G2215/0016 ,  G03G2215/00168

摘要： An image forming apparatus includes a rotatable belt member, a plurality of image forming members opposing the belt in an image forming region, a first detecting member configured to detect a position of the belt member with respect to a widthwise direction, a second detecting member configured to detect a moving direction, an adjusting roller configured to adjust the moving direction in the image forming region, the adjusting roller configured to adjust the moving direction in the image forming region, and a control portion configured to control a position of the adjusting roller on the basis of outputs of the first detecting member and the second detecting member without changing a position of the belt member in the image forming region in a direction perpendicular to a surface of the belt member.

摘要翻译： 图像形成装置包括可旋转的皮带部件，在图像形成区域中与皮带相对的多个图像形成部件，被配置为检测皮带部件相对于宽度方向的位置的第一检测部件， 检测移动方向，调节辊，被配置为调整图像形成区域中的移动方向，调节辊被配置为调整图像形成区域中的移动方向;以及控制部分，其被配置为控制调节辊的位置 第一检测构件和第二检测构件的输出的基础，而不改变带构件在图像形成区域中在垂直于带构件的表面的方向上的位置。