PHYTASE VARIANTS
    8.
    发明申请
    PHYTASE VARIANTS 审中-公开

    公开(公告)号:US20090029004A1

    公开(公告)日:2009-01-29

    申请号:US11753660

    申请日:2007-05-25

    CPC分类号: C12N9/16 A23K10/14 A23K20/189

    摘要: The present invention relates to phytase variants derived from a parent phytase which is homologous to a Peniophora lycii phytase and comprises at least one substitution in at least one of a number of positions corresponding to a position in the Peniophora lycii phytase. The variants are of improved properties, in particular of a higher specific activity and/or more thermostable than the parent phytase, e.g., of a Tm of up to 82° C. at pH 5.5, as determined by DSC, and/or of a doubted specific activity. The invention also relates to DNA encoding the phytase variants, methods of their production, as well as the use thereof, e.g., in animal feed and animal feed additives.

    摘要翻译: 本发明涉及衍生自母本植酸酶的植酸酶变体,所述植酸酶与青i i植酸酶同源,并且包括至少一个位于对应于Peniophora lycii植酸酶中的位置的位置中的至少一个取代。 这些变体具有改进的性质,特别是比母体植酸酶更高的比活性和/或更高的热稳定性,例如,通过DSC测定的在pH5.5达到82℃的Tm,和/或 怀疑具体活动。 本发明还涉及编码植酸酶变体的DNA,其生产方法及其用途,例如在动物饲料和动物饲料添加剂中。