公开(公告)号：US06475351B2

公开(公告)日：2002-11-05

申请号：US09772536

申请日：2001-01-30

申请人： Hoi Cheong Sun ,  Dominic Stephen Rosati ,  Eugene Samuel Puliniak ,  Bawa Singh ,  Nitin Vithalbhai Desai

发明人： Hoi Cheong Sun ,  Dominic Stephen Rosati ,  Eugene Samuel Puliniak ,  Bawa Singh ,  Nitin Vithalbhai Desai

IPC分类号： B01J1908

CPC分类号： H02N13/00 ,  B01J19/0046 ,  B01J2219/00468 ,  B01J2219/005 ,  G01N2035/00574 ,  Y10S118/02 ,  Y10T279/23

摘要： AC waveforms biasing of bead transporter chucks and their accumulated charge sensing circuits tailored for low resistivity substrates and beads where if traditional DC quasi-static biasing potentials were used, the bead attraction potentials of the chuck would undergo rapid RC decay and cause the bead transporter chuck to stop working. Methods for selecting AC waveforms are given, including those that maximize the time average of the bead attraction potential at the bead collection zone of the bead contact surface.

摘要翻译： 针对低电阻率基板和珠子的珠子运输卡盘的交流波形偏置及其积累的电荷感应电路，如果使用传统的直流准静态偏置电位，卡盘的珠子吸引电位将经历快速的RC衰减，并导致珠子运输卡盘 停止工作 给出了选择交流波形的方法，包括使珠接触表面的珠收集区的珠吸引电位的时间平均最大化的方法。

公开(公告)号：US06187149B1

公开(公告)日：2001-02-13

申请号：US09455678

申请日：1999-12-07

申请人： Hoi Cheong Sun ,  Dominic Stephen Rosati ,  Eugene Samuel Poliniak ,  Bawa Singh ,  Nitin Vithalbhai Desai

发明人： Hoi Cheong Sun ,  Dominic Stephen Rosati ,  Eugene Samuel Poliniak ,  Bawa Singh ,  Nitin Vithalbhai Desai

IPC分类号： B01J1908

CPC分类号： H02N13/00 ,  B01J19/0046 ,  B01J2219/00468 ,  B01J2219/005 ,  G01N2035/00574 ,  Y10S118/02 ,  Y10T279/23

摘要： AC waveforms biasing of bead transporter chucks and their accumulated charge sensing circuits tailored for low resistivity substrates and beads where if traditional DC quasi-static biasing potentials were used, the bead attraction potentials of the chuck would undergo rapid RC decay and cause the bead transporter chuck to stop working. Methods for selecting AC waveforms are given, including those that maximize the time average of the bead attraction potential at the bead collection zone of the bead contact surface.

摘要翻译： 针对低电阻率基板和珠子的珠子运输卡盘的交流波形偏置及其积累的电荷感应电路，如果使用传统的直流准静态偏置电位，卡盘的珠子吸引电位将经历快速的RC衰减，并导致珠子运输卡盘 停止工作 给出了选择交流波形的方法，包括使珠接触表面的珠收集区的珠吸引电位的时间平均最大化的方法。

公开(公告)号：US06752148B1

公开(公告)日：2004-06-22

申请号：US09623937

申请日：2000-09-01

申请人： Joseph T. McGinn ,  Suggy S. Chrai ,  Bogdan Brycki ,  Bawa Singh ,  Peter Coyle ,  Gary Santonastaso ,  Hoi Cheong Sun

发明人： Joseph T. McGinn ,  Suggy S. Chrai ,  Bogdan Brycki ,  Bawa Singh ,  Peter Coyle ,  Gary Santonastaso ,  Hoi Cheong Sun

IPC分类号： A61M1500

CPC分类号： A61M15/0045 ,  A61M15/0043 ,  A61M15/0048 ,  A61M15/0051 ,  A61M15/0055

摘要： An inhaler disc cartridge comprises a carrier disc with radially outwardly extending resilient fingers, each with a medicament powder dosage. A sealing disc and an indexing ring are bonded to the disc. A cam sequentially and manually deflects a selected finger causing it to snap against an anvil to release the dosage by momentum energy transfer. In other embodiments, a cassette includes a carrier substrate reel of deposited powder dosages with a dosage sealing tape. The substrate comprises a belt with a plurality of transversely extending triangular fingers, each finger tip with a dosage thereon. Each finger is snapped in sequence against an anvil while a clamp secures the belt as the fingers are deflected. The spring fingers are corrugated in one embodiment cooperating with an anvil having channels and a device for inducing agglomeration breakup air streams through the channels. Other embodiments are for impact deflection of a dosage carrying substrate in a cartridge or cassette against an anvil to release the dosages.

摘要翻译： 一个吸入式盘盒包括一个具有径向向外延伸的弹性指状物的承载盘，每个都带有药物粉末剂量。 密封盘和分度环结合到盘上。 凸轮顺序地并且手动地偏转所选择的手指，使其与砧座卡扣以通过动量能量传递释放剂量。 在其他实施例中，盒包括具有剂量密封带的沉积的粉末剂量的载体衬底卷轴。 衬底包括具有多个横向延伸的三角形指状物的带，每个指尖具有其上的剂量。 每个手指按照砧座顺序扣合，同时当手指偏转时，夹具固定皮带。 在一个实施例中，弹簧指状物是波纹状的，与具有通道的砧座配合，以及用于通过通道引起团聚分解空气流的装置。 其他实施方案是用于将剂量携带衬底在药筒或药盒中抵抗砧座的冲击挠曲以释放剂量。

公开(公告)号：US06295194B1

公开(公告)日：2001-09-25

申请号：US09393871

申请日：1999-09-10

申请人： Hoi Cheong Sun ,  Bawa Singh ,  Howard Christopher Rivenburg

发明人： Hoi Cheong Sun ,  Bawa Singh ,  Howard Christopher Rivenburg

IPC分类号： H02N1300

CPC分类号： B82Y15/00 ,  B01J2219/00468 ,  B01J2219/005 ,  H02N1/004

摘要： Provided is a method of moving a charged particle from a first position at which it is retained by a first electrode to a second position at which it is retained by a second electrode, the method comprising: applying a potential to the second electrode to attract the particle; and applying a potential to a guide electrode offset from the particle at the first position, wherein the applied potential is effective to reduce the attraction of the particle to the first position sufficiently to allow the potential applied at the second electrode to be effective to move the particle from the first position to the second position.

摘要翻译： 提供了一种将带电粒子从第一位置移动到第一位置的方法，其中第二位置被第二电极保持在第二位置，该方法包括：向第二电极施加电位以吸引 粒子; 以及将电位施加到在所述第一位置处偏离所述粒子的引导电极，其中所施加的电位有效地减小所述粒子对所述第一位置的吸引力，以足以允许施加在所述第二电极处的电位有效地移动 颗粒从第一位置到第二位置。

公开(公告)号：US06370005B1

公开(公告)日：2002-04-09

申请号：US09417736

申请日：1999-10-14

申请人： Hoi Cheong Sun ,  Nitin V. Desai ,  William R. Roach ,  David Norman Ludington ,  Timothy Allen Pletcher ,  David Keller ,  Frank B. Lang ,  Peter D. Southgate ,  Joseph T. McGinn

发明人： Hoi Cheong Sun ,  Nitin V. Desai ,  William R. Roach ,  David Norman Ludington ,  Timothy Allen Pletcher ,  David Keller ,  Frank B. Lang ,  Peter D. Southgate ,  Joseph T. McGinn

IPC分类号： H02N1300

CPC分类号： H01L21/6833 ,  H02N13/00

摘要： Provided is an electrostatic sensing chuck for attracting particles to a portion of a particle contact surface near a deposition electrode, the electrostatic sensing chuck comprising a pixel comprising: a deposition electrode (DE) for selectively establishing an attraction field (Ea) at the particle contact surface; a shield electrode (SE) oppositely biased with respect to the deposition electrode; a charge sensing circuit to measure charge accumulated on each of the deposition electrode and the shield electrode, wherein the charge sensing circuit subtracts a second charge it senses at the shield electrode from a first charge it senses at the deposition electrode, thereby determining accumulated charge at the deposition electrode balanced by accumulated charge at the shield electrode.

摘要翻译： 提供一种静电感测卡盘，用于将颗粒吸引到沉积电极附近的一部分颗粒接触表面，该静电感测卡盘包括一个像素，该像素包括：沉积电极（DE），用于选择性地在颗粒接触处建立吸引场（Ea） 表面; 相对于沉积电极相对偏置的屏蔽电极（SE）; 电荷感测电路，用于测量在每个沉积电极和屏蔽电极上累积的电荷，其中电荷感测电路在屏蔽电极处从其在沉积电极处感测到的第一电荷中减去其感测的第二电荷，由此确定累积电荷 沉积电极由屏蔽电极处的累积电荷平衡。

公开(公告)号：US5988432A

公开(公告)日：1999-11-23

申请号：US47631

申请日：1998-03-25

申请人： Hoi Cheong Sun

发明人： Hoi Cheong Sun

IPC分类号： B01L99/00 ,  B01J19/00 ,  B65G47/90 ,  B23Q7/04

CPC分类号： B82Y15/00 ,  B01J19/0046 ,  B65G47/90 ,  B01J2219/00468 ,  B01J2219/005

摘要： Bead manipulating chucks for selective pick up and discharge of polymer beads for chemical synthesis or analysis, whereby bead collection zones are recessed from bead contact surfaces. The strong dependence of the electrostatic image force on bead overall diameters provides a mechanism that sharply selects bead sizes that are successfully attracted and retained by the bead manipulating chuck. In this way, the bead manipulating chuck acts as an electrical analog to a low pass filter, only attracting and retaining beads of an overall diameter lower than a selected value.

摘要翻译： 珠操作卡盘用于选择性地拾取和排出用于化学合成或分析的聚合物珠，由此珠收集区从珠接触表面凹陷。 静电影像力对珠粒整体直径的强烈依赖性提供了一种机制，其可以锐利地选择珠粒操纵卡盘成功吸引和保持的珠粒尺寸。 以这种方式，珠操作卡盘用作低通滤波器的电模拟，仅吸引并保持总直径小于所选值的珠。

公开(公告)号：US6096368A

公开(公告)日：2000-08-01

申请号：US26303

申请日：1998-02-19

申请人： Hoi Cheong Sun

发明人： Hoi Cheong Sun

IPC分类号： G01N33/543 ,  B01J19/00 ,  B03C7/00 ,  G01N35/00 ,  G01N35/10 ,  A61J3/00 ,  B05D1/04 ,  B05D1/22 ,  B23B5/22 ,  C25D17/04

CPC分类号： G01N35/10 ,  B01J19/0046 ,  B01J2219/00468 ,  G01N2035/00237 ,  Y10T279/23

摘要： Bead transporter chucks for selective pick up and discharging of polymer beads for chemical synthesis or analysis, whereby repulsive field conductors are arranged around bead electrodes used for selectively attracting and retaining beads. Problems of bead control are addressed by adding repulsive fields to help guide and direct beads to desired or designated bead collection zones. The repulsive electrodes create non-uniform electric fields that control, focus, and deflect charged beads in the vicinity of the bead collection zone, helping prevent multiple bead retention at intended bead collection zones. For better bead control, and allowing manipulation of beads with higher charge/mass ratios, dielectric material may be positioned around the bead electrode and between the bead electrode and the repulsive field conductor. Multiple bead electrodes may be provided to form two or more bead collection zones, and these may selectively addressed and controlled (e.g, x-y addressing) for individual and selective control of the bead collection zones. Methods and applied voltages are given for using the bead transporter chuck to transport and dispense beads.

摘要翻译： 用于选择性地拾取和排出用于化学合成或分析的聚合物珠粒的珠状转运器卡盘，由此排斥场导体布置在用于选择性吸引和保留珠粒的珠粒电极周围。 通过添加排斥场来帮助引导和引导珠到期望的或指定的珠收集区来解决珠控制的问题。 排斥电极产生不均匀的电场，其控制，聚焦和偏转珠收集区附近的带电珠粒，有助于防止在预期的珠收集区域多个珠粒保留。 为了更好的珠粒控制，并且允许操纵具有较高电荷/质量比的珠子，可以将电介质材料定位在珠粒电极周围以及珠粒电极和排斥场导体之间。 可以提供多个胎圈电极以形成两个或更多个胎圈收集区，并且这些胎圈电极可以选择性地寻址和控制（例如，x-y寻址），用于个体和选择性地控制胎圈收集区。 给出方法和施加的电压，以使用胎圈传送器卡盘来输送和分配珠子。

公开(公告)号：US06491241B1

公开(公告)日：2002-12-10

申请号：US09417820

申请日：1999-10-14

申请人： Hoi Cheong Sun

发明人： Hoi Cheong Sun

IPC分类号： B02C1906

CPC分类号： B02C23/08 ,  B02C19/06

摘要： Provided is, among other things, and together with associated methods, a powder feed comprising: a venturi comprising an external gas inlet, a gas outlet through which gas flows at a rate amplified over a gas flow rate into the external gas inlet, and an internal gas inlet; and a cyclone with an intake port connected to the venturi gas outlet, a recycle outlet port, and a product port, wherein a gas flow rate FS into the venturi external gas inlet results in an enhanced flow rate into the cyclone intake port.

摘要翻译： 除了别的以外，还包括与相关方法一起提供的粉末进料，其包括：文丘里管，其包括外部气体入口，气体出口，气体以通过气体流速扩散到外部气体入口中的速率流动，以及 内部气体入口; 以及具有与文丘里气体出口连接的进气口的旋风分离器，再循环出口和产品端口，其中进入文丘里管外部气体入口的气体流量FS导致进入旋风分离器进气口的增加的流量。

公开(公告)号：US06168666A

公开(公告)日：2001-01-02

申请号：US09083487

申请日：1998-05-22

申请人： Hoi Cheong Sun

发明人： Hoi Cheong Sun

IPC分类号： B05B5025

CPC分类号： B82Y15/00 ,  B01J19/0046 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00648 ,  B01J2219/00659 ,  B05B5/047 ,  B05B5/08 ,  B05B17/0646

摘要： Acoustic bead charger/dispenser employs a bead dispersion plate (BDP) to align beads with, for example, bead collection zones of a bead transporter chuck, then propel or launch them toward the bead collection zones, using acoustic energy provided by a speaker. The bead dispersion plate can be configured so that the acoustic energy from the speaker may be directed so as to impart to the bead translational kinetic energy primarily in a direction toward the bead collection zone of the bead transporter chuck. The bead dispersion plate can comprise a conductive surface that can be used to accelerate the beads toward the bead transporter chuck. Using sufficient acoustic energy applied by the speaker, sufficient translational kinetic energy can be imparted to beads to remove them from the conductive surface when they are under the influence of an electrostatic image force. The bead dispersion plate can optionally comprise a tribo-charging mesh (MESH) for inductive charge transfer tribo-charging during application of acoustic energy. The bead dispersion plate can comprise a distribution system, including a bead reservoir and metering pump to controllably feed and retrieve the beads from the bead dispersion zones of the bead dispersion plate. Methods are given for using the acoustic bead charger/dispenser to align beads with a bead collection zone of a bead transporter chuck, and to propel the beads toward the bead collection zone.

摘要翻译： 声珠充电器/分配器使用珠粒分散板（BDP）将珠与例如珠传送器卡盘的珠收集区域对准，然后使用扬声器提供的声能来将其推向或发射到珠收集区。 珠分散板可以被配置为使得来自扬声器的声能可以被引导以便主要在朝向胎圈传送器卡盘的胎圈收集区的方向上赋予胎圈平移动能。 珠粒分散板可以包括导电表面，该导电表面可用于将珠子朝向胎圈输送器卡盘加速。 使用由扬声器施加的足够的声能，当它们处于静电影像力的影响下时，能够将珠子赋予足够的平移动能以将其从导电表面移除。 珠分散板可以可选地包括用于在施加声能期间进行感应电荷转移摩擦充电的摩擦充电网（MESH）。 珠分散板可以包括分配系统，包括珠粒储存器和计量泵，以可控地从珠粒分散板的珠分散区域进给和回收珠粒。 给出了使用声珠充电器/分配器将珠子与珠传送器卡盘的珠收集区域对准的方法，并将珠子推向珠收集区域。

公开(公告)号：US06724609B2

公开(公告)日：2004-04-20

申请号：US10038931

申请日：2002-01-04

申请人： Hoi Cheong Sun ,  Nitin V. Desai ,  William R. Roach ,  David Norman Ludington ,  Timothy Allen Pletcher ,  David Keller ,  Frank B. Lang ,  Peter D. Southgate ,  Joseph T. McGinn

发明人： Hoi Cheong Sun ,  Nitin V. Desai ,  William R. Roach ,  David Norman Ludington ,  Timothy Allen Pletcher ,  David Keller ,  Frank B. Lang ,  Peter D. Southgate ,  Joseph T. McGinn

IPC分类号： H02H2300

CPC分类号： H01L21/6833 ,  H02N13/00

摘要： Provided is an electrostatic sensing chuck for attracting particles to a portion of a particle contact surface near a deposition electrode, the electrostatic sensing chuck comprising a pixel comprising: a deposition electrode (DE) for selectively establishing an attraction field (Ea) at the particle contact surface; a shield electrode (SE) oppositely biased with respect to the deposition electrode; a charge sensing circuit to measure charge accumulated on each of the deposition electrode and the shield electrode, wherein the charge sensing circuit subtracts a second charge it senses at the shield electrode from a first charge it senses at the deposition electrode, thereby determining accumulated charge at the deposition electrode balanced by accumulated charge at the shield electrode.

摘要翻译： 提供一种静电感测卡盘，用于将颗粒吸引到沉积电极附近的一部分颗粒接触表面，该静电感测卡盘包括一个像素，该像素包括：沉积电极（DE），用于选择性地在颗粒接触处建立吸引场（Ea） 表面; 相对于沉积电极相对偏置的屏蔽电极（SE）; 电荷感测电路，用于测量在每个沉积电极和屏蔽电极上累积的电荷，其中电荷感测电路在屏蔽电极处从其在沉积电极处感测到的第一电荷中减去其感测的第二电荷，由此确定累积电荷 沉积电极由屏蔽电极处的累积电荷平衡。