摘要:
The invention relates to various embodiments of a bioanalytical reagent with at least one vesicle, generated from a living cell, comprising at least one receptor, characterized in that a mechanism of signal transduction triggered by said receptor in the cell used for vesicle generation is preserved in said vesicle, as a component of the bioanalytical reagent. The invention further relates to methods for production of the bioanalytical reagent according to the invention, to bioanalytical detection methods based on the application of said reagent, and to the use of said detection method and of the bioanalytical reagent.
摘要:
The invention relates to various embodiments of a bioanalytical reagent with at least one vesicle, generated from a living cell, comprising at least one receptor, characterized in that a mechanism of signal transduction triggered by said receptor in the cell used for vesicle generation is preserved in said vesicle, as a component of the bioanalytical reagent. The invention further relates to methods for production of the bioanalytical reagent according to the invention, to bioanalytical detection methods based on the application of said reagent, and to the use of said detection method and of the bioanalytical reagent.
摘要:
Systems for positioning and/or analyzing samples such as cells, vesicles, cellular organelles, and fragments, derivatives, and mixtures thereof, for electrical and/or optical analysis, especially relating to the presence and/or activity of ion channels.
摘要:
Systems for positioning and/or analyzing samples such as cells, vesicles, cellular organelles, and fragments, derivatives, and mixtures thereof, for electrical and/or optical analysis, especially relating to the presence and/or activity of ion channels.
摘要:
Systems for positioning and/or analyzing samples such as cells, vesicles, cellular organelles, and fragments, derivatives, and mixtures thereof, for electrical and/or optical analysis, especially relating to the presence and/or activity of ion channels.
摘要:
A monitor located about 100 m from the ILS localizer determines whether the DDM alarm threshold was exceeded due to an equipment error or to an error caused by an overflying aircraft. To accomplish this, either the maximum of the frequency spectrum of the variation with time of the differentiated DDM signal is located, or the frequency spectrum of the variation with time of the DDM signal or of the differentiated DDM signal is compared with one or a plurality of spectra typical of equipment errors or of errors caused by overflying aircraft.
摘要:
High-density arrays of attoliter volume elements can be created within minutes in a parallel and effortless manner by using self-assembly of nanometer-sized components (e.g., lipid vesicles containing (bio)chemicals) based on biological recognition. The ultrasmall volumes allow localization to a predefined position of a few or single molecules, and then screening for their (bio)chemical properties or performing confined (bio)chemical reactions.
摘要:
In a method for installing an offshore tension leg platform, a freely floating platform structure (7) is coupled to previously mounted tension legs (1) without the use of temporary motion compensating coupling mechanisms between the upper ends of the tension legs and the platform structure. Instead, permanently installed coupling elements (5) at the ends of the tension legs (1) are used and during the transition of the platform structure (7) from freely floating condition to moored condition by means of the tension legs (1), the coupling elements (5) are allowed to impact quite heavily against the corresponding connecting means (9) on the platform structure during its wave induced movements until it is held continuously by the tension legs. By making the tension legs (1) of exact length and arranging these in three groups which are coupled simultaneously to the platform structure, one can avoid any post-installation adjustment of the attachment points (5,9) of the tension legs (1) in the platform structure (7). In order to shorten the period during which impacts occur in the attachment points (5,9), the draft of the platform structure (7) can quickly be changed by releasing a larger weight (14) therefrom or pulling the platform to the side with respect to its equilibrium position during a transition phase.
摘要:
Apparatus for filling cartons having three upstanding side walls and a horizontal side wall with stacks of paper sheets has a horizontal conveyor reciprocable into and from a carton while the carton is held at a filling station, a system for delivering stacks to that portion of the conveyor which enters a carton at the filling station, and a locating device installed at a level above the path of movement of stacks with the conveyor portion and having an indexible horizontal shaft for two fingers which are disposed opposite each other, and an indexing mechanism for the shaft. The shaft is indexed to a first position in which one finger extends into the path of movement of an oncoming stack during delivery of the stack onto the conveyor, thereupon throuh 90.degree. to ensure that the fingers cannot interfere with introduction of the stack into the carton, and again through 90.degree. when the stack enters the carton to thus ensure that the stack is stripped off the conveyor by the other finger while the conveyor is being withdrawn from the station. That finger which strips a stack off the conveyor thereupon retains its position until engaged by the next stack so that the next stack is properly oriented prior to introduction into the next empty carton at the filling station.
摘要:
A novel DME transponder having a plurality of directional antennas arranged equidistantly on a circle each having a radial, highly directional pattern and as a group covering 360.degree. in the azimuth plane. The antennas are divided into at least two groups of nonadjacent antennas. Each group is connected to a receiver. The DME reply signal is radiated from the group containing the antenna which has received the DME interrogation signal with the greatest amplitude. The signal radiated in the direction of the interrogator is the DME reply signal, and the signals radiated in the other directions are used as filler pulses.