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    NITROGENOUS-RING ACYLGUANIDINE DERIVATIVE
    4.
    发明申请
    NITROGENOUS-RING ACYLGUANIDINE DERIVATIVE 有权
    硝基环丙酰胺衍生物

    公开(公告)号：US20120142727A1

    公开(公告)日：2012-06-07

    申请号：US13388872

    申请日：2010-08-05

    申请人： Isao Kinoyama ,  Takehiro Miyazaki ,  Yohei Koganemaru ,  Takuya Washio ,  Wataru Hamaguchi

    发明人： Isao Kinoyama ,  Takehiro Miyazaki ,  Yohei Koganemaru ,  Takuya Washio ,  Wataru Hamaguchi

    IPC分类号： A61K31/472 ,  C07D217/14 ,  C07D215/60 ,  A61P25/00 ,  A61K31/4709 ,  A61P25/28 ,  A61P25/18 ,  C07D215/48 ,  A61K31/47

    CPC分类号： C07D215/48 ,  C07D215/54 ,  C07D215/60 ,  C07D217/02 ,  C07D217/14 ,  C07D217/16 ,  C07D217/22 ,  C07D401/04

    摘要： [Object] An excellent agent for preventing or treating dementia, schizophrenia, and the like, based on serotonin 5-HT5A receptor modulating action, is provided.[Means for Solution] It was confirmed that acylguanidine derivatives (the following formula I; any one of Z1, Z2, Z3, Z4 and Z5 is nitrogen atom, and the others are carbon atoms) which have the characteristic structure in which the guanidine is bonded to one ring of the quinoline or isoquinoline via a carbonyl group, and a cyclic group is bonded to the other ring, exhibit potent 5-HT5A receptor modulating actions and excellent pharmacological actions based on the 5-HT5A receptor modulating action, and thus can be excellent agents for preventing or treating dementia, schizophrenia, bipolar disorder, or attention deficit hyperactivity disorder. Thus, the present invention has been completed.

    摘要翻译： 提供了一种基于5-羟色胺5-HT5A受体调节作用预防或治疗痴呆，精神分裂症等的优异剂。 [解决方案]确认酰基胍衍生物（下式I，Z 1，Z 2，Z 3，Z 4和Z 5中的任一个为氮原子，其余为碳原子），其特征在于胍 通过羰基与喹啉或异喹啉的一个环键合，并且环状基团与另一个环键合，表现出基于5-HT5A受体调节作用的有效的5-HT5A受体调节作用和优异的药理作用，因此可以 是预防或治疗痴呆，精神分裂症，双相情感障碍或注意缺陷多动障碍的优良药剂。 因此，本发明已经完成。

    VEHICLE DATA ABNORMALITY DETERMINATION DEVICE
    7.
    发明申请
    VEHICLE DATA ABNORMALITY DETERMINATION DEVICE 有权
    车辆数据异常确定装置

    公开(公告)号：US20130166989A1

    公开(公告)日：2013-06-27

    申请号：US13642146

    申请日：2010-07-08

    申请人： Takehiro Miyazaki

    发明人： Takehiro Miyazaki

    IPC分类号： H03M13/05

    CPC分类号： H03M13/05 ,  F02D41/26 ,  F02D2041/228 ,  G06F21/57 ,  G06F21/64 ,  H03M13/09 ,  H03M13/11 ,  H04L1/0057 ,  H04L1/0061

    摘要： Disclosed is a vehicle data abnormality determination device including a storage unit for pre-storing a 2-byte remainder term which is a result of a CRC arithmetic operation on a target area for arithmetic operations in a predetermined memory area, and an arithmetic operation unit for performing a CRC arithmetic operation while including the 2-byte remainder term in this CRC arithmetic operation. Because when performing the CRC arithmetic operation, the vehicle data abnormality determination device performs the CRC arithmetic operation while including the 2-byte remainder term in this CRC arithmetic operation after performing an arithmetic operation on the target area, the vehicle data abnormality determination device always makes the computed result be zero when the data has not been falsified, and can detect whether or not the data has been falsified easily and properly.

    摘要翻译： 本发明公开了一种车辆数据异常判定装置，其特征在于，包括：存储部，其将预定存储区域中的算术运算对象区域的CRC算术运算结果的2字节剩余项预先存储;以及算术运算单元， 在该CRC算术运算中包括2字节余数项，执行CRC算术运算。 由于在执行CRC算术运算时，车辆数据异常判定装置在对该目标区域进行算术运算后，在该CRC运算中包括2字节的余数项，进行CRC运算运算，车辆数据异常判定装置始终进行 当数据没有被伪造时，计算结果为零，并且可以检测数据是否已被轻易正确地伪造。

    Vehicle data abnormality determination device
    8.
    发明授权
    Vehicle data abnormality determination device 有权
    车辆数据异常判定装置

    公开(公告)号：US09172398B2

    公开(公告)日：2015-10-27

    申请号：US13642146

    申请日：2010-07-08

    申请人： Takehiro Miyazaki

    发明人： Takehiro Miyazaki

    IPC分类号： H03M13/00 ,  H03M13/05 ,  H03M13/09 ,  H03M13/11 ,  F02D41/26 ,  G06F21/64 ,  H04L1/00 ,  F02D41/22

    CPC分类号： H03M13/05 ,  F02D41/26 ,  F02D2041/228 ,  G06F21/57 ,  G06F21/64 ,  H03M13/09 ,  H03M13/11 ,  H04L1/0057 ,  H04L1/0061

    摘要： Disclosed is a vehicle data abnormality determination device including a storage unit for pre-storing a 2-byte remainder term which is a result of a CRC arithmetic operation on a target area for arithmetic operations in a predetermined memory area, and an arithmetic operation unit for performing a CRC arithmetic operation while including the 2-byte remainder term in this CRC arithmetic operation. Because when performing the CRC arithmetic operation, the vehicle data abnormality determination device performs the CRC arithmetic operation while including the 2-byte remainder term in this CRC arithmetic operation after performing an arithmetic operation on the target area, the vehicle data abnormality determination device always makes the computed result be zero when the data has not been falsified, and can detect whether or not the data has been falsified easily and properly.

    摘要翻译： 本发明公开了一种车辆数据异常判定装置，其特征在于，包括：存储部，其将预定存储区域中的算术运算对象区域的CRC算术运算结果的2字节剩余项预先存储;以及算术运算单元， 在该CRC算术运算中包括2字节余数项，执行CRC算术运算。 由于在执行CRC算术运算时，车辆数据异常判定装置在对该目标区域进行算术运算后，在该CRC运算中包括2字节的余数项，进行CRC运算运算，车辆数据异常判定装置始终进行 当数据没有被伪造时，计算结果为零，并且可以检测数据是否已被轻易正确地伪造。