公开(公告)号：US20170282130A1

公开(公告)日：2017-10-05

申请号：US15599841

申请日：2017-05-19

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Takahiko HARIYAMA ,  Yasuharu TAKAKU ,  Hiroshi SUZUKI ,  Masatsugu SHIMOMURA ,  Daisuke ISHII ,  Isao OHTA ,  Yoshinori MURANAKA

IPC: B01D71/38 ,  B01D67/00 ,  B01D69/12 ,  B01D69/02 ,  C09D4/06 ,  C09D4/00

CPC classification number: B01D71/38 ,  B01D67/009 ,  B01D69/02 ,  B01D69/127 ,  B01D2323/30 ,  B01D2325/36 ,  C09D4/00 ,  C09D4/06

Abstract: Provided is a technique for fabricating a novel thin membrane with a starting material such as a biocompatible compound that is not easily processible into a membrane, particularly a technique for fabricating a novel thin membrane of a composition that is gradually polymerized from a membrane surface into the membrane in the cross sectional direction of the membrane, and having, for example, different structures on the front and back of the membrane. The technique includes the steps of preparing a solution of a starting material compound; forming a thin membrane of the solution on a base material surface; and forming the organic polymer thin membrane through a polymerization reaction caused by irradiating the exposed surface of the thin membrane with a plasma or an electron beam.

公开(公告)号：US20160343539A1

公开(公告)日：2016-11-24

申请号：US15114978

申请日：2015-01-28

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Takahiko HARIYAMA ,  Yasuharu TAKAKU ,  Hiroshi SUZUKI ,  Satoshi HIRAKAWA ,  Hideaki KAWASAKI ,  Masatsugu SHIMOMURA ,  Daisuke ISHII ,  Isao OHTA ,  Yoshinori MURANAKA

IPC: H01J37/20 ,  G01N33/50 ,  H01J37/22 ,  G01N33/483

CPC classification number: H01J37/20 ,  G01N33/4833 ,  G01N33/5011 ,  G01N2223/612 ,  G01N2800/7028 ,  H01J37/22 ,  H01J2237/2002 ,  H01J2237/2007

Abstract: Provided are a protective agent for electron microscopic observation in a vacuum which can protect a biological sample in a water-containing state, such as a mammal, a plant tissue or a cultured cell, and a single cell in the living state without deforming it even in a vacuum, a kit using the same, methods for observation, diagnosis, evaluation, and quantification of a sample by an electron microscope, and a sample stage to be used for the observation. The protective agent for electron microscopic observation of the present invention contains a a component to impart the survival environment, a saccharide, and an electrolyte.

Abstract translation: 提供一种用于真空中电子显微镜观察的保护剂，其可以保护生物状态中的含水状态的生物样品例如哺乳动物，植物组织或培养细胞，以及单一细胞，而不使其变形甚至 在真空中，使用其的试剂盒，通过电子显微镜观察，诊断，评价和定量样品的方法以及用于观察的样品台。 本发明的电子显微镜观察用保护剂含有赋予生存环境的成分，糖类和电解质。

公开(公告)号：US20170044002A1

公开(公告)日：2017-02-16

申请号：US15305467

申请日：2015-04-22

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Takahiko HARIYAMA ,  Daisuke ISHII ,  Masatsugu SHIMOMURA ,  Ko OKUMURA ,  Marie TANI

IPC: B81B1/00 ,  B01L3/00

CPC classification number: B01L3/5027 ,  B01L3/50273 ,  B01L3/502746 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0858 ,  B01L2300/087 ,  B01L2300/0877 ,  B01L2400/0406 ,  B01L2400/086 ,  B81B1/00 ,  B81B2201/058 ,  B81B2203/0392 ,  F16K99/0017 ,  F16K99/0021 ,  Y10T137/206 ,  Y10T137/2224 ,  Y10T137/85938

Abstract: A combined-blade-type open flow path device being a fluid flow path device where a plurality of flow paths are adjacent to each other, the combined-blade-type open flow path device comprising: a substrate configured to constitute a bottom portion of the flow paths; and a plurality of blades erected on a surface of the substrate, the plurality of blades configured to constitute side walls of the flow paths, wherein the plurality of blades are erected in a plurality of numbers at a space in a direction from an upstream side to a downstream side of a flow of the fluid, and conduction of the fluid between the flow paths adjacent at the space is made possible, and wherein the flow of the fluid is made possible by one end of the flow path being in contact with the fluid.

Abstract translation: 一种组合刀片式开放流路装置，其是多个流路彼此相邻的流体流路装置，所述组合叶片型开放流路装置包括：基板，其构成为构成所述 流路; 以及多个叶片，其竖立在所述基板的表面上，所述多个叶片构造成构成所述流路的侧壁，其中，所述多个叶片在从上游侧到 流体的流动的下游侧和在空间相邻的流动路径之间的流体的传导成为可能，并且其中流体的流动可以由流动路径的一端与流体接触 。