公开(公告)号：US07613785B2

公开(公告)日：2009-11-03

申请号：US10719229

申请日：2003-11-20

申请人： James C. Chen ,  Minh-Ngoc L. Huynh ,  Matthew J. Kalos ,  Chung M. Fung

发明人： James C. Chen ,  Minh-Ngoc L. Huynh ,  Matthew J. Kalos ,  Chung M. Fung

IPC分类号： G06F7/00

CPC分类号： G06F3/065 ,  G06F3/0611 ,  G06F3/067 ,  G06F3/0689 ,  H04L47/10

摘要： Methods, system and computer program product are provided to improve the efficiency of data transfers in a PPRC environment. Any or all of three features may be implemented, each of which reduces the number of round trips required for the exchange of handshaking, data and control information. A first feature includes disabling the “transfer ready” acknowledgment which normally occurs between a primary storage controller and a secondary storage controller. A second feature includes pre-allocating payload and data buffers in the secondary storage controller. A third feature includes packaging write control information with a write command in an extended command descriptor block (CDB). Such a step eliminated the need for a separate transmission of the write control information. The CDB is transmitted along with a data block from the primary storage controller to the secondary storage controller and placed in the respective, pre-allocated buffers. Data may also be pipelined to the secondary. By decreasing the response time for data transfers, the distance separating the primary and secondary storage controllers may be increased.

摘要翻译： 提供了方法，系统和计算机程序产品，以提高PPRC环境中数据传输的效率。 可以实现三个特征中的任何一个或全部，每个特征减少交换握手，数据和控制信息所需的往返次数。 第一个功能包括禁用通常在主存储控制器和辅助存储控制器之间发生的“传送就绪”确认。 第二特征包括在副存储控制器中预分配有效载荷和数据缓冲器。 第三个特征包括在扩展命令描述符块（CDB）中用写入命令封装写入控制信息。 这样的步骤消除了对写入控制信息的单独发送的需要。 CDB与来自主存储控制器的数据块一起传送到辅助存储控制器并且被放置在相应的预先分配的缓冲器中。 数据也可以流水线到次级。 通过减少数据传输的响应时间，可以增加分离主存储控制器和辅助存储控制器的距离。

公开(公告)号：US07873744B2

公开(公告)日：2011-01-18

申请号：US12117112

申请日：2008-05-08

申请人： James C. Chen ,  Patricia C. Lu ,  Chung M. Fung ,  Minh-Ngoc L. Huynh ,  Christopher M. Sansone ,  Dung N. Dang ,  Gail A. Spear ,  Richard A. Ripberger

发明人： James C. Chen ,  Patricia C. Lu ,  Chung M. Fung ,  Minh-Ngoc L. Huynh ,  Christopher M. Sansone ,  Dung N. Dang ,  Gail A. Spear ,  Richard A. Ripberger

IPC分类号： G06F15/00

CPC分类号： H04L67/1097 ,  H04L29/12801 ,  H04L61/6004

摘要： System and computer program product are provided to configure a path between nodes through a fabric in a fibre channel storage area network (SAN). A node name is provided for a target node on the SAN and a port name is provided for each port in the target node. A relationship is established in a data structure between each port name and a slot in which each port is physically located in the target node. Prior to configuring a path between a source node and a port in the target node, the ports which are physically connected and logged in to the fabric are identified by port address. The port names corresponding to the port addresses are then identified. The port names are used to generate interface_ids of the ports corresponding to the physical slots in which the ports are located. A data structure is created to maintain the relationship between interface_ids and port names. To establish a path connection between a port in the source node and a selected port in the target node, the node name of the target node and the interface_id of the selected port are input to the data structure and the port name of the selected port is output. The port name is then used to obtain the address of the selected port and an I/O session path opened between the source and target nodes.

摘要翻译： 提供系统和计算机程序产品，以通过光纤通道存储区域网络（SAN）中的结构来配置节点之间的路径。 为SAN上的目标节点提供节点名称，并为目标节点中的每个端口提供端口名称。 在每个端口名称和每个端口物理上位于目标节点的时隙之间的数据结构中建立关系。 在目标节点中的源节点和端口之间配置路径之前，物理连接并登录到结构的端口由端口地址标识。 然后识别与端口地址对应的端口名称。 端口名称用于生成与端口所在物理槽相对应的端口的接口ID。 创建数据结构以维护interface_ids和端口名称之间的关系。 要在源节点中的端口和目标节点的选定端口之间建立路径连接，将目标节点的节点名称和所选端口的interface_id输入到数据结构，所选端口的端口名称为 输出。 然后使用端口名称来获取所选端口的地址以及在源节点和目标节点之间打开的I / O会话路径。

公开(公告)号：US07523207B2

公开(公告)日：2009-04-21

申请号：US10719179

申请日：2003-11-20

申请人： James C. Chen ,  Patricia C. Lu ,  Chung M. Fung ,  Minh-Ngoc L. Huynh ,  Christopher M. Sansone ,  Dung N. Dang ,  Gail A. Spear ,  Richard A. Ripberger

发明人： James C. Chen ,  Patricia C. Lu ,  Chung M. Fung ,  Minh-Ngoc L. Huynh ,  Christopher M. Sansone ,  Dung N. Dang ,  Gail A. Spear ,  Richard A. Ripberger

IPC分类号： G06F15/16 ,  G06F15/173 ,  G06F15/177

CPC分类号： H04L67/1097 ,  H04L29/12801 ,  H04L61/6004

摘要： Methods, system and computer program product are provided to configure a path between nodes through a fabric in a fibre channel storage area network (SAN). A node name is provided for a target node on the SAN and a port name is provided for each port in the target node. A relationship is established in a data structure between each port name and a slot in which each port is physically located in the target node. Prior to configuring a path between a source node and a port in the target node, the ports which are physically connected and logged in to the fabric are identified by port address. The port names corresponding to the port addresses are then identified. The port names are used to generate interface_ids of the ports corresponding to the physical slots in which the ports are located. A data structure is created to maintain the relationship between interface_ids and port names. To establish a path connection between a port in the source node and a selected port in the target node, the node name of the target node and the interface_id of the selected port are input to the data structure and the port name of the selected port is output. The port name is then used to obtain the address of the selected port and an I/O session path opened between the source and target nodes.

摘要翻译： 提供方法，系统和计算机程序产品，以通过光纤通道存储区域网络（SAN）中的结构来配置节点之间的路径。 为SAN上的目标节点提供节点名称，并为目标节点中的每个端口提供端口名称。 在每个端口名称和每个端口物理上位于目标节点的时隙之间的数据结构中建立关系。 在目标节点中的源节点和端口之间配置路径之前，物理连接并登录到结构的端口由端口地址标识。 然后识别与端口地址对应的端口名称。 端口名称用于生成与端口所在物理槽相对应的端口的接口ID。 创建数据结构以维护interface_ids和端口名称之间的关系。 要在源节点中的端口和目标节点的选定端口之间建立路径连接，将目标节点的节点名称和所选端口的interface_id输入到数据结构，所选端口的端口名称为 输出。 然后使用端口名称来获取所选端口的地址以及在源节点和目标节点之间打开的I / O会话路径。

公开(公告)号：US20080205299A1

公开(公告)日：2008-08-28

申请号：US12117112

申请日：2008-05-08

申请人： James C. Chen ,  Patricia C. Lu ,  Chung M. Fung ,  Minh-Ngoc L. Huynh ,  Christopher M. Sansone ,  Dung N. Dang ,  Gail A. Spear ,  Richard A. Ripberger

发明人： James C. Chen ,  Patricia C. Lu ,  Chung M. Fung ,  Minh-Ngoc L. Huynh ,  Christopher M. Sansone ,  Dung N. Dang ,  Gail A. Spear ,  Richard A. Ripberger

IPC分类号： H04L12/28

CPC分类号： H04L67/1097 ,  H04L29/12801 ,  H04L61/6004

摘要： System and computer program product are provided to configure a path between nodes through a fabric in a fibre channel storage area network (SAN). A node name is provided for a target node on the SAN and a port name is provided for each port in the target node. A relationship is established in a data structure between each port name and a slot in which each port is physically located in the target node. Prior to configuring a path between a source node and a port in the target node, the ports which are physically connected and logged in to the fabric are identified by port address. The port names corresponding to the port addresses are then identified. The port names are used to generate interface_ids of the ports corresponding to the physical slots in which the ports are located. A data structure is created to maintain the relationship between interface_ids and port names. To establish a path connection between a port in the source node and a selected port in the target node, the node name of the target node and the interface_id of the selected port are input to the data structure and the port name of the selected port is output. The port name is then used to obtain the address of the selected port and an I/O session path opened between the source and target nodes.

摘要翻译： 提供系统和计算机程序产品，以通过光纤通道存储区域网络（SAN）中的结构来配置节点之间的路径。 为SAN上的目标节点提供节点名称，并为目标节点中的每个端口提供端口名称。 在每个端口名称和每个端口物理上位于目标节点的时隙之间的数据结构中建立关系。 在目标节点中的源节点和端口之间配置路径之前，物理连接并登录到结构的端口由端口地址标识。 然后识别与端口地址对应的端口名称。 端口名称用于生成与端口所在物理槽相对应的端口的接口ID。 创建数据结构以维护interface_ids和端口名称之间的关系。 要在源节点中的端口和目标节点的选定端口之间建立路径连接，将目标节点的节点名称和所选端口的interface_id输入到数据结构，所选端口的端口名称为 输出。 然后使用端口名称来获取所选端口的地址以及在源节点和目标节点之间打开的I / O会话路径。

公开(公告)号：US07117118B2

公开(公告)日：2006-10-03

申请号：US10911904

申请日：2004-08-04

申请人： Matthew J. Kalos ,  Michael T. Benhase ,  James C. Chen ,  Patricia C. Lu

发明人： Matthew J. Kalos ,  Michael T. Benhase ,  James C. Chen ,  Patricia C. Lu

IPC分类号： G06F15/00 ,  G06F17/18 ,  G06F19/00

CPC分类号： G06F11/3409 ,  G06F3/0605 ,  G06F3/0653 ,  G06F3/067 ,  G06F11/3485 ,  G06F2201/88

摘要： Computer networks are provided with a resource efficient ability to generate link performance statistics. Two counters accumulates the number of I/O operations processed by a link and the time required by the link to complete each I/O operation. The average link utilization per I/O operation may then be calculated. The number of operations per second for a link may be computed by dividing the output from the first counter by a predetermined period of time and the average number of operations using the link may be computed by dividing the output from the second counter by the predetermined period of time. An optional third counter may be employed to accumulate the number of bytes transferred by a link during each I/O operation and used to compute the average size of an I/O operation. The generated statistics are useful for such activities as problem resolution, load balancing and capacity planning.

摘要翻译： 计算机网络具有生成链路性能统计资源的资源有效能力。 两个计数器累加链接处理的I / O操作的数量以及链接完成每个I / O操作所需的时间。 然后可以计算每个I / O操作的平均链路利用率。 可以通过将来自第一计数器的输出除以预定时间段来计算链路每秒的操作次数，并且可以通过将来自第二计数器的输出除以预定周期来计算使用该链路的平均操作次数 的时间。 可以使用可选的第三计数器来累积每个I / O操作期间由链路传送的字节数，并用于计算I / O操作的平均大小。 生成的统计信息对于解决问题，负载平衡和容量规划等活动非常有用。

公开(公告)号：US20120149091A1

公开(公告)日：2012-06-14

申请号：US11608527

申请日：2006-12-08

申请人： Brian D. Wilkerson ,  James C. Chen ,  John Pulse ,  Andrei Guschin ,  Michael Weaver

发明人： Brian D. Wilkerson ,  James C. Chen ,  John Pulse ,  Andrei Guschin ,  Michael Weaver

IPC分类号： C12N1/12 ,  C12N1/00 ,  C12M1/02 ,  C12M1/42

CPC分类号： C12P7/649 ,  C12M21/02 ,  C12M31/10 ,  C12M41/06 ,  C12M41/36 ,  C12N1/12 ,  C12N13/00 ,  C12P7/6463 ,  C12P39/00 ,  Y02E50/13 ,  Y02E50/343 ,  Y02P20/134

摘要： Systems, devices, and methods for cultivating biomasses. A bioreactor system is operable for growing photosynthetic organisms. The bioreactor system includes a bioreactor and a lighting system. The lighting system includes one more light-emitting substrates configured to light at least some of a plurality of photosynthetic organisms retained in the bioreactor.

摘要翻译： 用于培育生物质的系统，装置和方法。 生物反应器系统可用于生长光合生物。 生物反应器系统包括生物反应器和照明系统。 照明系统包括一个以上的发光基板，其被配置为点亮保留在生物反应器中的多个光合生物中的至少一些光合生物。

公开(公告)号：US08097028B2

公开(公告)日：2012-01-17

申请号：US11357358

申请日：2006-02-17

申请人： James C. Chen ,  Nicholas Yeo ,  Phillip Burwell ,  Thomas Wenger

发明人： James C. Chen ,  Nicholas Yeo ,  Phillip Burwell ,  Thomas Wenger

IPC分类号： A61N5/06

CPC分类号： A61K41/0071 ,  A61N5/0601 ,  A61N5/062 ,  A61N2005/0602 ,  A61N2005/0651 ,  A61N2005/0661

摘要： The present invention provides a prophylactic light activated treatment method for subjects at risk of a plaque-mediated thrombotic event, such as acute coronary syndromes. In one embodiment, the subject receives a dose of photosensitizer sufficient to result in a concentration of photosensitizer in the neovascularization associated with atherosclerotic disease to permit effective photodynamic therapy. Light of a wavelength that excites the photosensitizer, but that does not to any significant extent penetrate to an adventitial layer of the blood vessel, is applied to the region of the blood vessel. The therapeutic light dose, which may be applied in sequential stages, is sufficient to cause closure of neovasculature leakage and lead to plaque stabilization and reduced adverse clinical outcomes. The present invention further provides light transmission devices and systems useful in carrying out the methods of the present invention.

摘要翻译： 本发明为患有斑块介导的血栓形成事件风险的受试者，例如急性冠状动脉综合征提供预防性光活化治疗方法。 在一个实施方案中，受试者接受足以导致与动脉粥样硬化疾病相关的新血管形成中的光敏剂浓度以允许有效的光动力疗法的剂量的光敏剂。 激发光敏剂的波长的光被施加到血管的区域，而不是任何显着程度的透射到血管的外膜层。 可以按顺序施用的治疗光剂量足以引起新血管渗漏的闭合并导致斑块稳定化并减少不良临床结果。 本发明还提供了用于实施本发明的方法的光传输装置和系统。

公开(公告)号：US20110009464A1

公开(公告)日：2011-01-13

申请号：US12817068

申请日：2010-06-16

申请人： James C. Chen

发明人： James C. Chen

IPC分类号： A61K31/407 ,  A61P35/00

CPC分类号： A61K41/0057 ,  A61K9/0019 ,  A61K31/407

摘要： The efficacy of light activated therapy treatment is enhanced by stimulating the immune system of the patient substantially above the pre-therapy level. Abnormal tissue that is destroyed by the light activated therapy releases factors that stimulate the immune system, leading to systemic reductions in abnormal tissue (i.e., reduction beyond the area treated using light), so long as the light therapy conditions favor apoptosis over necrosis. The volume of abnormal tissue destroyed is maximized to the extent possible, reducing tumor load, which reduces an amount of immunosuppressive factors in the body, enabling stimulation of the immune system to be successful.

摘要翻译： 通过刺激患者的免疫系统显着高于治疗前水平，提高了光活化治疗的疗效。 被光激活治疗破坏的异常组织释放刺激免疫系统的因素，导致异常组织的系统性减少（即，除了使用光治疗的区域之外减少），只要光疗条件有利于凋亡超过坏死。 破坏的异常组织的体积尽可能地最大化，减少肿瘤负荷，这减少了身体中的免疫抑制因子的量，使得能够刺激免疫系统成功。

公开(公告)号：US20110008372A1

公开(公告)日：2011-01-13

申请号：US12832494

申请日：2010-07-08

申请人： James C. Chen

发明人： James C. Chen

IPC分类号： A61K39/395 ,  A61K31/58 ,  A61K31/395 ,  A61K31/69 ,  A61K31/165 ,  A61K31/704 ,  A61P35/00

CPC分类号： A61K31/165 ,  A61K31/395 ,  A61K31/58 ,  A61K31/69 ,  A61K31/704

摘要： The efficacy of light activated therapy treatment is enhanced by use of additional therapeutic agents. Abnormal tissue is destroyed by light activated therapy, and the associated administration of one or more additional therapeutic agents can synergistically enhance the therapy. For example, the concepts disclosed herein encompass the use of the following agents in combination with light activated drug therapy: (1) agents that selectively inhibit heat shock protein 90 (Hsp90); (2) agents that inhibit the Hedgehog pathway (which is believed to play a central role in allowing the proliferation and survival of certain cancer-causing cells, and which is implicated in many of the most deadly cancers); and, (3) agents for reducing the anti-apoptotic effects of Bcl-2 or Bcl-xL. These agents can be used with light activated drug therapy individually, or in various combinations and permutations.

摘要翻译： 通过使用额外的治疗剂来增强光活化治疗的疗效。 异常组织被光激活治疗破坏，并且相关的一种或多种另外的治疗剂的施用可以协同增强治疗。 例如，本文公开的概念包括以下试剂与光活化药物治疗的组合的用途：（1）选择性抑制热休克蛋白90（Hsp90）的药剂; （2）抑制Hedgehog途径的药物（被认为在允许某些致癌细胞的增殖和存活中发挥核心作用，并且涉及许多致命的癌症）; 和（3）降低Bcl-2或Bcl-xL的抗凋亡作用的药剂。 这些药物可以单独使用轻度活化药物治疗，或以各种组合和排列使用。

公开(公告)号：US06396443B1

公开(公告)日：2002-05-28

申请号：US08665755

申请日：1996-06-18

申请人： Kenneth F. Conklin ,  David B. Giguere ,  James C. Chen

发明人： Kenneth F. Conklin ,  David B. Giguere ,  James C. Chen

IPC分类号： H01Q124

CPC分类号： H01Q1/22 ,  H01Q13/28 ,  H01Q21/061 ,  H01Q23/00

摘要： A point-to-point radio frequency unit/antenna has a flat antenna, preferably a continuous transverse stub antenna, integrated into the housing of the microwave unit. The radio frequency unit/antenna includes a housing having an exterior wall, a microwave radio frequency transceiver electronics package within the housing and having an antenna connection, and a flat antenna affixed to one face of the exterior wall of the housing. A microwave radio frequency feed communicates between the flat antenna and the antenna connection of the microwave transceiver electronics package. There is preferably a bracket structure on another face of the housing to affix the housing to a support.

摘要翻译： 点对点射频单元/天线具有集成到微波单元的壳体中的平坦天线，优选地是连续的横向短截线天线。 射频单元/天线包括具有外壁的外壳，壳体内的微波射频收发器电子封装，并且具有天线连接，以及固定到外壳的外壁的一个面上的平坦天线。 微波射频馈送在平坦天线和微波收发器电子封装的天线连接之间进行通信。 在壳体的另一个表面上优选地具有支架结构，以将壳体固定到支撑件上。