公开(公告)号：US06452371B1

公开(公告)日：2002-09-17

申请号：US09563107

申请日：2000-05-02

Applicant: James M Brugger

Inventor： James M Brugger

IPC: G01N2700

CPC classification number: A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3658 ,  A61M1/3659 ,  A61M1/3661 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708 ,  G01F1/7088

Abstract: A flow rate of a fluid flowing in a tube is quantitatively determined by altering the electrical conductivity of the fluid by injection of a bolus of saline. The electrical conductivity of the altered conductivity is measured over the time it takes the altered conductivity fluid to pass a conductivity measuring location. The measured conductivity is integrated over the time it takes to pass the conductivity measuring location. The integral is interpreted to determine the flow rate.

Abstract translation: 在管中流动的流体的流速通过注射大量盐水改变流体的电导率而定量地确定。 在改变的导电流体通过电导率测量位置的时间内测量改变的导电性的导电性。 测量的电导率在通过电导率测量位置所需的时间内积分。 积分被解释为确定流量。

公开(公告)号：US06582385B2

公开(公告)日：2003-06-24

申请号：US09027301

申请日：1998-02-19

Applicant: Jeffrey H Burbank ,  C David Finch ,  James M Brugger

Inventor： Jeffrey H Burbank ,  C David Finch ,  James M Brugger

IPC: A61M3700

CPC classification number: A61M1/3472 ,  A61M1/28 ,  A61M1/3437 ,  A61M1/3458 ,  A61M1/3482 ,  A61M1/3486 ,  A61M2205/3306 ,  A61M2205/3389 ,  Y10S210/90

Abstract: A hemofiltration system is provided in which ultrafiltrate is purified by reverse osmosis for reinfusion. Non-sterile infusate concentrate is dialyzed into the purified ultrafiltrate and combined with cleared blood which is returned to the patient. In another system, a hemofilter is used to sterilize essentially pure, non-sterile water for dilution of sterile infusate concentrate, then the hemofilter is used to filter blood, the infusate concentrate being combined with cleared blood for return to the patient.

Abstract translation: 提供了一种血液滤过系统，其中超滤液通过反渗透纯化用于再灌注。 将非无菌灌注浓缩物透析至纯化的超滤液中，并与清除的血液结合并返回给患者。 在另一个系统中，使用血液过滤器对基本上纯净的非无菌水进行灭菌以稀释无菌灌注浓缩物，然后使用血液滤膜来过滤血液，将输注的浓缩物与清除的血液结合以返回给患者。

公开(公告)号：US07758082B2

公开(公告)日：2010-07-20

申请号：US11951142

申请日：2007-12-05

Applicant: William Weigel ,  Kenneth Everett Buckler ,  Jeffrey H Burbank ,  James M Brugger ,  David Farias De Souza

Inventor： William Weigel ,  Kenneth Everett Buckler ,  Jeffrey H Burbank ,  James M Brugger ,  David Farias De Souza

IPC: F16L55/00

CPC classification number: A61M39/1011 ,  A61M2039/1016 ,  A61M2039/1033 ,  Y10S604/905

Abstract: Devices having various features to prevent the disconnection of connectors used in medical treatments are disclosed. The devices can prevent disconnection of luer connectors that are incompletely mated.

Abstract translation: 公开了具有防止医疗处理中使用的连接器断开的各种特征的装置。 这些设备可以防止未完全配对的路厄连接器断开连接。

公开(公告)号：US06589482B1

公开(公告)日：2003-07-08

申请号：US09512927

申请日：2000-02-25

Applicant: Jeffrey H. Burbank ,  James M Brugger ,  Dennis M. Treu

Inventor： Jeffrey H. Burbank ,  James M Brugger ,  Dennis M. Treu

IPC: A61M114

CPC classification number: A61M1/34 ,  A61M1/1639 ,  A61M1/3403 ,  A61M1/341 ,  A61M1/342 ,  A61M1/3441 ,  A61M1/3444 ,  A61M1/3448 ,  A61M1/3458 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3626 ,  A61M1/3639 ,  A61M1/3646 ,  A61M1/367 ,  A61M39/0208 ,  A61M2205/126 ,  A61M2205/128 ,  A61M2205/15 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/35 ,  A61M2205/3553 ,  A61M2205/3569 ,  A61M2205/505 ,  A61M2205/60 ,  A61M2205/6018 ,  A61M2205/6072 ,  Y10S210/929

Abstract: An extracorporeal fluid circuit for performing hemofiltration defines within a flexible panel a flow channel that is free of an air interface. The flexible panel includes an in-line sensor region through which fluid pressure in the flow channel can be measured by an external sensor. The systems and methods enable sensing fluid pressure through the in-line sensor region using the external sensor. The flow channel can convey, e.g., waste from the hemofilter or replacement fluid for return to the individual.

Abstract translation: 用于进行血液滤过的体外流体回路在柔性面板内限定了没有空气界面的流动通道。 柔性面板包括一个在线传感器区域，流体通道中的流体压力可以通过外部传感器测量。 该系统和方法使得能够使用外部传感器来检测通过在线传感器区域的流体压力。 流动通道可以传送例如来自血液过滤器的废物或替换流体以返回到个体。

公开(公告)号：US6075367A

公开(公告)日：2000-06-13

申请号：US220139

申请日：1998-12-23

Applicant: James M Brugger

Inventor： James M Brugger

IPC: A61M1/16 ,  A61M1/36 ,  G01F1/704 ,  G01F1/708 ,  G01N27/02 ,  G01N33/487 ,  G01N27/08 ,  G01P5/08

CPC classification number: A61M1/16 ,  A61M1/361 ,  A61M1/3612 ,  A61M1/3653 ,  A61M1/3658 ,  A61M1/3669 ,  G01F1/7046 ,  G01F1/708 ,  G01F1/7088

Abstract: A flow rate of a fluid flowing in a tube is quantitatively determined by altering the electrical conductivity of the fluid by injection of a bolus of saline. The electrical conductivity of the altered conductivity is measured over the time it takes the altered conductivity fluid to pass a conductivity measuring location. The measured conductivity is integrated over the time it take to pass the conductivity measuring location. The integral is interpreted to determine the flow rate.