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    Processes for preparing 3-arylsulfur hydroxamic acids
    8.
    发明授权
    Processes for preparing 3-arylsulfur hydroxamic acids 失效
    制备3-芳基硫异羟肟酸的方法

    公开(公告)号：US06420573B1

    公开(公告)日：2002-07-16

    申请号：US09991143

    申请日：2001-11-09

    申请人： Jeffrey Allen Campbell ,  Lawrence Emerson Fisher ,  Charles Alois Dvorak ,  Paul Leo McGrane

    发明人： Jeffrey Allen Campbell ,  Lawrence Emerson Fisher ,  Charles Alois Dvorak ,  Paul Leo McGrane

    IPC分类号： C07D30906

    CPC分类号： C07D309/08 ,  C07C319/14 ,  C07C319/20 ,  C07C323/20

    摘要： This invention provides processes for the preparation of a compound of Formula I: Y—C(═O)—C(R1)(R2)—CH2—S(O)nR3 wherein: Y is hydroxy or XONX, where each X is independently hydrogen, lower alkyl or lower acyl; R1 is hydrogen or lower alkyl; R2 is hydrogen, lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, or R1 and R2 together with the carbon atom to which they are attached form a cycloalkyl or heterocyclo group; R3 is aryl; and n is 0, 1 or 2. The invention also provides novel aryl haloalkyl sulfide intermediates useful for the preparation of compounds of Formula I and novel methods of preparing aryl alkyl sulfides.

    摘要翻译： 本发明提供制备式I化合物的方法：其中：Y是羟基或XONX，其中每个X独立地是氢，低级烷基或低级酰基; R 1是氢或低级烷基; R 2是氢，低级烷基，芳基 ，芳烷基，环烷基，环烷基烷基或R 1和R 2与它们所连接的碳原子一起形成环烷基或杂环基; R 3为芳基; 和n为0,1或2.本发明还提供了可用于制备式I化合物的新型芳基卤代烷基硫化物中间体和制备芳基烷基硫化物的新方法。

    Processes for preparing 3-Arylsulfur hydroxamic acids
    9.
    发明授权
    Processes for preparing 3-Arylsulfur hydroxamic acids 失效
    制备3-芳基硫异羟肟酸的方法

    公开(公告)号：US06342639B1

    公开(公告)日：2002-01-29

    申请号：US09335447

    申请日：1999-06-17

    申请人： Jeffrey Allen Campbell ,  Lawrence Emerson Fisher ,  Charles Alois Dvorak ,  Paul Leo McGrane

    发明人： Jeffrey Allen Campbell ,  Lawrence Emerson Fisher ,  Charles Alois Dvorak ,  Paul Leo McGrane

    IPC分类号： C07C32106

    CPC分类号： C07D309/08 ,  C07C319/14 ,  C07C319/20 ,  C07C323/20

    摘要： This invention provides processes for the preparation of a compound of Formula I: Y—C(═O—C(R1)(R2)—CH2—S(O)nR3 wherein: Y is hydroxy or XONX, where each X is independently hydrogen, lower alkyl or lower acyl; R1 is hydrogen or lower alkyl; R2 is hydrogen, lower alkyl, aryl, aralkyl, cycloalkyl, cycloalkylalkyl, or R1 and R2 together with the carbon atom to which they are attached form a cycloalkyl or heterocyclo group; R3 is aryl; and n is 0, 1 or 2. The invention also provides novel aryl haloalkyl sulfide intermediates useful for the preparation of compounds of Formula I and novel methods of preparing aryl alkyl sulfides.

    摘要翻译： 本发明提供制备式I化合物的方法：其中：Y是羟基或XONX，其中每个X独立地是氢，低级烷基或低级酰基; R 1是氢或低级烷基; R 2是氢，低级烷基，芳基 ，芳烷基，环烷基，环烷基烷基或R 1和R 2与它们所连接的碳原子一起形成环烷基或杂环基; R 3为芳基; 和n为0,1或2.本发明还提供了可用于制备式I化合物的新型芳基卤代烷基硫化物中间体和制备芳基烷基硫化物的新方法。