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    SELF-ASSEMBLY OF MOLECULAR DEVICES
    1.
    发明申请
    SELF-ASSEMBLY OF MOLECULAR DEVICES 审中-公开
    分子装置自组装

    公开(公告)号：US20070297216A1

    公开(公告)日：2007-12-27

    申请号：US11740170

    申请日：2007-04-25

    申请人： James Tour ,  Jiping Yang ,  Philipp Harder ,  David Allara ,  Paul Weiss ,  Long Cheng ,  Paul Franzon ,  David Nackashi

    发明人： James Tour ,  Jiping Yang ,  Philipp Harder ,  David Allara ,  Paul Weiss ,  Long Cheng ,  Paul Franzon ,  David Nackashi

    IPC分类号： G11C11/56 ,  B05D1/04 ,  C25D5/00 ,  H01L45/00 ,  H01L21/62 ,  C25D5/10

    CPC分类号： H01L51/0595 ,  B82Y10/00 ,  C25D9/00 ,  H01L51/005 ,  H01L51/0075

    摘要： A method for selectively assembling a molecular device on a substrate comprises contacting the first substrate with a solution containing molecular devices; impeding bonding of the molecular devices to the substrate such that application of a voltage potential to the substrate results in assembly of the molecular device on the substrate at a rate that is at least 1.5 times the rate of assembly of the molecular device on a voltage-neutral substrate; and applying a voltage potential to the substrate so as to cause the molecular devices to assemble on the substrate. A nanoscale computing device is described that includes a substrate, a pair of conductive input/output electrodes carried on this substrate and disposed in spaced-apart relationship and a substantially disordered assembly of nanowires formed on the substrate in a region between the electrodes, thereby forming at least one programmable conductive pathway between the pair of electrodes.

    摘要翻译： 用于在基片上选择性地组装分子器件的方法包括使第一底物与含有分子器件的溶液接触; 妨碍分子器件与衬底的结合，使得向衬底施加电压电位导致分子器件在衬底上的组装速度至少是分子器件在电压 - 电压上的组装速度的1.5倍， 中性底物; 以及向所述衬底施加电压电位以使所述分子器件组装在所述衬底上。 描述了一种纳米尺度计算装置，其包括衬底，一对导电输入/输出电极，该导电输入/输出电极承载在该衬底上并以间隔的关系设置，并且在电极之间的区域中形成在衬底上的基本上无序的纳米线组件，从而形成 在一对电极之间的至少一个可编程导电路径。

    Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
    2.
    发明申请
    Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same 有权
    用于治疗和/或诊断应用的可负载聚合物颗粒及其制备和使用方法

    公开(公告)号：US20060088476A1

    公开(公告)日：2006-04-27

    申请号：US11257535

    申请日：2005-10-25

    申请人： Philipp Harder ,  Olaf Fritz ,  Ulf Fritz

    发明人： Philipp Harder ,  Olaf Fritz ,  Ulf Fritz

    IPC分类号： A61K49/04

    CPC分类号： A61K9/5031 ,  A61K9/1641 ,  A61K9/1694 ,  A61K9/5073 ,  A61K9/5078 ,  A61K9/5089 ,  A61K49/0404 ,  A61K49/0419

    摘要： Particles are provided for use in therapeutic and/or diagnostic procedures. The particles include poly[bis(trifluoroethoxy) phosphazene] and/or a derivatives thereof which may be present throughout the particles or within an outer coating of the particles. The particles can also include a core having a hydrogel formed from an acrylic-based polymer. Barium sulfate may also be provided to the core of the particles as a coating or absorbed within the core of the particles. The particles can be used to minimize blood flow to mammalian tissues by occluding at least a portion of a blood vessel of the mammal, or to deliver an active agent to a localized area within a body of a mammal by contacting a localized area with at least one of the particles. Further, the particles are useful in sustained release formulations including active agent(s) for oral administration, as tracer particles for injection into the bloodstream of a mammal or for use in enhanced ultrasound imaging. The particles may include agents for increasing density for achieving useful buoyancy levels in suspension.

    摘要翻译： 颗粒被提供用于治疗和/或诊断过程。 颗粒包括聚[双（三氟乙氧基）磷腈]和/或其衍生物，其可以存在于整个颗粒中或颗粒的外涂层内。 颗粒还可以包括具有由丙烯酸类聚合物形成的水凝胶的芯。 也可以将硫酸钡作为涂层提供到颗粒的芯部或者被吸收在颗粒的芯中。 颗粒可以用于通过闭塞哺乳动物的血管的至少一部分来最小化对哺乳动物组织的血液流动，或者通过使至少一个局部区域与至少一个局部区域接触而将活性剂递送到哺乳动物体内的局部区域 其中一颗颗粒。 此外，该颗粒可用于持续释放制剂，包括用于口服给药的活性剂，作为用于注射到哺乳动物血流中的示踪剂颗粒或用于增强的超声成像。 颗粒可以包括增加密度的试剂，以实现悬浮液中有用的浮力水平。

    POLYAMIDE MOLDING MATERIAL, THE USE THEREOF, AND MOLDED PARTS PRODUCED THEREFROM
    4.
    发明申请
    POLYAMIDE MOLDING MATERIAL, THE USE THEREOF, AND MOLDED PARTS PRODUCED THEREFROM 有权
    聚酰胺模塑材料，其使用及其制造的模具

    公开(公告)号：US20140329944A1

    公开(公告)日：2014-11-06

    申请号：US14360543

    申请日：2011-12-23

    申请人： Philipp Harder ,  Herbert Mossauer

    发明人： Philipp Harder ,  Herbert Mossauer

    IPC分类号： C08L77/06 ,  B29C45/00

    CPC分类号： C08L77/06 ,  B29C45/0001 ,  B29C2945/00 ,  B29K2077/00 ,  B29K2105/0026 ,  B29L2031/3481 ,  C08G69/265 ,  C08G69/36 ,  C08J2377/10 ,  C08K7/14 ,  C09K21/12

    摘要： A polyamide molding material is proposed, which comprises at least one partially crystalline, partially aromatic polyamide (A) and at least one amorphous polyamide (B). The polyamides (A) and (B) together make up 30-60 wt.-% of the polyamide molding material. Furthermore, the polyamide molding material comprises 40-70 wt.-% glass fibers (C) having flat cross section, 0-15 wt.-% of at least one nonhalogenated flame retardant (D), and 0-10 wt.-% further additives (E), the components (A) to (E) adding up to 100 wt.-% of the polyamide molding material. The at least one partially crystalline, partially aromatic polyamide (A) has a glass transition temperature of at least 105° C. The polyamide molding material according to the invention is preferably distinguished in an injection-molding burr formation test in that, at a melt temperature of 320° C. and a tool temperature of 90° C., and a dynamic pressure of 100 bar and a holding pressure of 400 bar, at the flow path end of a mold arm having a vent gap dimension of 30 μm, burrs having a length G of at most 30 μm result. Such a polyamide molding material results in molded parts having good surface quality and low warpage when injection molded and is suitable for the production of housings or housing parts of electrical and electronic devices.

    摘要翻译： 提出了一种聚酰胺成型材料，其包含至少一种部分结晶的部分芳族聚酰胺（A）和至少一种无定形聚酰胺（B）。 聚酰胺（A）和（B）一起占聚酰胺成型材料的30-60重量％。 此外，聚酰胺成型材料包含40-70重量％的具有平坦横截面的玻璃纤维（C），0-15重量％的至少一个非卤化阻燃剂（D）和0-10重量％ 其他添加剂（E），组分（A）至（E）加入聚酰胺成型材料的100重量％。 所述至少一种部分结晶的部分芳族聚酰胺（A）的玻璃化转变温度至少为105℃。根据本发明的聚酰胺成型材料优选在注射成型毛刺形成试验中区分，因为在熔体 温度为320℃，工具温度为90℃，动态压力为100巴，保持压力为400巴，在通气口尺寸为30微米的模具臂的流路端，毛刺 长度G为30μm以下。 这种聚酰胺成型材料在注射成型时产生具有良好的表面质量和低翘曲的成型部件，并且适用于电气和电子设备的壳体或壳体部件的制造。

    LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME
    5.
    发明申请
    LOADABLE POLYMERIC PARTICLES FOR THERAPEUTIC AND/OR DIAGNOSTIC APPLICATIONS AND METHODS OF PREPARING AND USING THE SAME 审中-公开
    用于治疗和/或诊断应用的负载聚合物颗粒及其制备和使用方法

    公开(公告)号：US20130052142A1

    公开(公告)日：2013-02-28

    申请号：US13623151

    申请日：2012-09-20

    申请人： Philipp Harder ,  Olaf Fritz ,  Ulf Fritz

    发明人： Philipp Harder ,  Olaf Fritz ,  Ulf Fritz

    IPC分类号： A61K9/50 ,  A61K47/34 ,  A61P1/00 ,  A61P7/00 ,  A61P35/00 ,  A61K49/04 ,  A61K31/80 ,  A61K49/22

    CPC分类号： A61K9/5031 ,  A61K9/1641 ,  A61K9/1694 ,  A61K9/5073 ,  A61K9/5078 ,  A61K9/5089 ,  A61K49/0404 ,  A61K49/0419

    摘要： Particles are provided for use in therapeutic and/or diagnostic procedures. The particles include poly[bis(trifluoroethoxy)phosphazene] and/or a derivatives thereof which may be present throughout the particles or within an outer coating of the particles. The particles can also include a core having a hydrogel formed from an acrylic-based polymer. Barium sulfate may also be provided to the core of the particles as a coating or absorbed within the core of the particles. The particles can be used to minimize blood flow to mammalian tissues by occluding at least a portion of a blood vessel of the mammal, or to deliver an active agent to a localized area within a body of a mammal by contacting a localized area with at least one of the particles. Further, the particles are useful in sustained release formulations including active agent(s) for oral administration, as tracer particles for injection into the bloodstream of a mammal or for use in enhanced ultrasound imaging. The particles may include agents for increasing density for achieving useful buoyancy levels in suspension.

    摘要翻译： 颗粒被提供用于治疗和/或诊断过程。 颗粒包括聚[双（三氟乙氧基）磷腈]和/或其衍生物，其可以存在于整个颗粒中或颗粒的外涂层内。 颗粒还可以包括具有由丙烯酸类聚合物形成的水凝胶的芯。 也可以将硫酸钡作为涂层提供到颗粒的芯部或者被吸收在颗粒的芯中。 颗粒可以用于通过闭塞哺乳动物的血管的至少一部分来最小化对哺乳动物组织的血液流动，或者通过使至少一个局部区域与至少一个局部区域接触而将活性剂递送到哺乳动物体内的局部区域 其中一颗颗粒。 此外，该颗粒可用于持续释放制剂，包括用于口服给药的活性剂，作为用于注射到哺乳动物血流中的示踪剂颗粒或用于增强的超声成像。 颗粒可以包括增加密度的试剂，以实现悬浮液中有用的浮力水平。

    Polyamide molding material, the use thereof, and molded parts produced therefrom
    7.
    发明授权
    Polyamide molding material, the use thereof, and molded parts produced therefrom 有权

    公开(公告)号：US09845389B2

    公开(公告)日：2017-12-19

    申请号：US14360543

    申请日：2011-12-23

    申请人： Philipp Harder ,  Herbert Mossauer

    发明人： Philipp Harder ,  Herbert Mossauer

    IPC分类号： B60C1/00 ,  C08L77/06 ,  C08G69/26 ,  C08G69/36 ,  C09K21/12 ,  B29C45/00 ,  B29K77/00 ,  B29K105/00 ,  B29L31/34

    CPC分类号： C08L77/06 ,  B29C45/0001 ,  B29C2945/00 ,  B29K2077/00 ,  B29K2105/0026 ,  B29L2031/3481 ,  C08G69/265 ,  C08G69/36 ,  C08J2377/10 ,  C08K7/14 ,  C09K21/12

    摘要： A polyamide molding material is proposed, which comprises at least one partially crystalline, partially aromatic polyamide (A) and at least one amorphous polyamide (B). The polyamides (A) and (B) together make up 30-60 wt.-% of the polyamide molding material. Furthermore, the polyamide molding material comprises 40-70 wt.-% glass fibers (C) having flat cross section, 0-15 wt.-% of at least one nonhalogenated flame retardant (D), and 0-10 wt.-% further additives (E), the components (A) to (E) adding up to 100 wt.-% of the polyamide molding material. The at least one partially crystalline, partially aromatic polyamide (A) has a glass transition temperature of at least 105° C. The polyamide molding material according to the invention is preferably distinguished in an injection-molding burr formation test in that, at a melt temperature of 320° C. and a tool temperature of 90° C., and a dynamic pressure of 100 bar and a holding pressure of 400 bar, at the flow path end of a mold arm having a vent gap dimension of 30 μm, burrs having a length G of at most 30 μm result. Such a polyamide molding material results in molded parts having good surface quality and low warpage when injection molded and is suitable for the production of housings or housing parts of electrical and electronic devices.

    High-temperature polyamide molding compounds reinforced with flat glass fibers
    9.
    发明授权
    High-temperature polyamide molding compounds reinforced with flat glass fibers 有权
    用平板玻璃纤维增​​强的高温聚酰胺模塑料

    公开(公告)号：US08324307B2

    公开(公告)日：2012-12-04

    申请号：US12198002

    申请日：2008-08-25

    申请人： Philipp Harder ,  Thomas Jeltsch ,  Nikolai Lamberts

    发明人： Philipp Harder ,  Thomas Jeltsch ,  Nikolai Lamberts

    IPC分类号： C08K3/40 ,  C08K3/00 ,  C08G18/34 ,  C08L77/02 ,  C08L77/04

    CPC分类号： C08G69/26 ,  C08G69/265 ,  C08G69/36 ,  C08K7/14 ,  C08K2201/016 ,  C08L77/06 ,  C08L2205/16

    摘要： The present invention relates to reinforced polyamide molding compounds containing high-melting partially aromatic polyamides and flat glass fibers, in particular with a rectangular cross section, i.e., glass fibers with a noncircular cross-sectional area and a dimension ratio of the main cross-sectional axis to the secondary cross-sectional axis of 2 to 6, in particular 3 to 6, most especially preferably from 3.5 to 5.0. The present invention also relates to a method for manufacturing polyamide molding compounds and molded articles manufactured therefrom, i.e., in particular injection-molded parts. The inventive molded parts have a high transverse stiffness and transverse strength.

    摘要翻译： 本发明涉及含有高熔点部分芳族聚酰胺和扁平玻璃纤维的增强聚酰胺模塑料，特别是具有矩形横截面，即具有非圆形横截面积的玻璃纤维和主横截面的尺寸比 轴的次级横截面轴为2至6，特别是3至6，最特别优选为3.5至5.0。 本发明还涉及一种用于制造由其制造的聚酰胺模塑料及其模塑制品的方法，特别是注模部件。 本发明的模制件具有高横向刚度和横向强度。

    Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
    10.
    发明授权
    Loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same 有权
    用于治疗和/或诊断应用的可负载聚合物颗粒及其制备和使用方法

    公开(公告)号：US08318209B2

    公开(公告)日：2012-11-27

    申请号：US11257535

    申请日：2005-10-25

    申请人： Philipp Harder ,  Olaf Fritz ,  Ulf Fritz

    发明人： Philipp Harder ,  Olaf Fritz ,  Ulf Fritz

    IPC分类号： A61K9/16 ,  A61K9/14 ,  A61K9/50 ,  A61K49/04 ,  A61F2/00 ,  A61F13/00 ,  C08G79/02

    CPC分类号： A61K9/5031 ,  A61K9/1641 ,  A61K9/1694 ,  A61K9/5073 ,  A61K9/5078 ,  A61K9/5089 ,  A61K49/0404 ,  A61K49/0419

    摘要： Particles are provided for use in therapeutic and/or diagnostic procedures. The particles include poly[bis(trifluoroethoxy) phosphazene] and/or a derivatives thereof which may be present throughout the particles or within an outer coating of the particles. The particles can also include a core having a hydrogel formed from an acrylic-based polymer. Barium sulfate may also be provided to the core of the particles as a coating or absorbed within the core of the particles. The particles can be used to minimize blood flow to mammalian tissues by occluding at least a portion of a blood vessel of the mammal, or to deliver an active agent to a localized area within a body of a mammal by contacting a localized area with at least one of the particles. Further, the particles are useful in sustained release formulations including active agent(s) for oral administration, as tracer particles for injection into the bloodstream of a mammal or for use in enhanced ultrasound imaging. The particles may include agents for increasing density for achieving useful buoyancy levels in suspension.

    摘要翻译： 颗粒被提供用于治疗和/或诊断过程。 颗粒包括聚[双（三氟乙氧基）磷腈]和/或其衍生物，其可以存在于整个颗粒中或颗粒的外涂层内。 颗粒还可以包括具有由丙烯酸类聚合物形成的水凝胶的芯。 也可以将硫酸钡作为涂层提供到颗粒的芯部或者被吸收在颗粒的芯中。 颗粒可以用于通过闭塞哺乳动物的血管的至少一部分来最小化对哺乳动物组织的血液流动，或者通过使至少一个局部区域与至少一个局部区域接触而将活性剂递送到哺乳动物体内的局部区域 其中一颗颗粒。 此外，该颗粒可用于持续释放制剂，包括用于口服给药的活性剂，作为用于注射到哺乳动物血流中的示踪剂颗粒或用于增强的超声成像。 颗粒可以包括增加密度的试剂，以实现悬浮液中有用的浮力水平。