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公开(公告)号：US10730950B2
公开(公告)日：2020-08-04
申请号：US15453451
申请日：2017-03-08
Applicant: Janssen Biotech, Inc.
Inventor： Cam Holland , John Kehoe , Linda Snyder , Alejandro Sepulveda , Daniel Villarreal
IPC: C07K16/28 , A61K39/00 , A61K39/395 , A61K45/06 , A61P31/20 , A61P31/04 , A61K39/08 , A61K39/12 , A61K39/39
Abstract: Provided herein are antibodies that specifically bind to GITR. Also described are related polynucleotides capable of encoding the provided GITR-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to enhance an immune response in a subject against cancer.
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公开(公告)号：US20220348647A1
公开(公告)日：2022-11-03
申请号：US17853218
申请日：2022-06-29
Applicant: Janssen Biotech, Inc.
Inventor： Ken Boakye , Alfred Del Vecchio , John Kehoe , Eilyn Lacy , Lynne Murray , Mary Ryan , Sandra Santulli-Marotto , John Wheeler , Brian Whitaker , Alexey Teplyakov
IPC: C07K16/24
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：US09248194B2
公开(公告)日：2016-02-02
申请号：US14338391
申请日：2014-07-23
Applicant: Janssen Biotech, Inc.
Inventor： Daphne Ann Salick Ryan , John Kehoe , John Wheeler , Chunlin Yang , Abla Creasy
IPC: A61K47/42 , C07K16/24 , A61K39/395 , A61K39/00
CPC classification number: A61K47/42 , A61K39/3955 , A61K2039/505 , C07K7/08 , C07K14/525 , C07K16/241 , C07K2317/24 , C07K2317/76 , C07K2317/92
Abstract: We have disclosed affinity peptides toward infliximab. More specifically we have disclosed an affinity biomatrix where the affinity peptide is covalently attached to a biocompatible, biodegradable polymer. The affinity biomatrix is useful in preparing controlled release devices for infliximab.
Abstract translation: 我们已经向英夫利昔单抗公开了亲和肽。 更具体地，我们已经公开了一种亲和力生物基质，其中亲和肽共价连接到生物相容的可生物降解的聚合物上。 亲和力生物基质可用于制备英夫利昔单抗的控制释放装置。
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公开(公告)号：US11414484B2
公开(公告)日：2022-08-16
申请号：US17060362
申请日：2020-10-01
Applicant: Janssen Biotech, Inc.
Inventor： Ken Boakye , Alfred Del Vecchio , John Kehoe , Eilyn Lacy , Lynne Murray , Mary Ryan , Sandra Santulli-Marotto , John Wheeler , Brian Whitaker , Alexey Teplyakov
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：US08906649B2
公开(公告)日：2014-12-09
申请号：US13760663
申请日：2013-02-06
Applicant: Janssen Biotech, Inc.
Inventor： John Kehoe , Tatiana Ort , Kristen Picha , Mary Ryan , John Wheeler , Jennifer Lee Gardiner
CPC classification number: C07K16/18 , A61K2039/505 , C07K2317/21 , C07K2317/33 , C07K2317/55 , C07K2317/92
Abstract: The present invention relates to antibodies against human collagen II, polypeptides and polynucleotides encoding human collagen II antibodies or fragments thereof, and methods of making and using the foregoing.
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Patent Agency Ranking
公开(公告)号：US20140220634A1
公开(公告)日：2014-08-07
申请号：US13760663
申请日：2013-02-06
Applicant: JANSSEN BIOTECH, INC.
Inventor： John Kehoe , Tatiana Ort , Kristen Picha , Mary Ryan , John Wheeler , Jennifer Lee Gardiner
IPC: C07K16/18
CPC classification number: C07K16/18 , A61K2039/505 , C07K2317/21 , C07K2317/33 , C07K2317/55 , C07K2317/92
Abstract: The present invention relates to antibodies against human collagen II, polypeptides and polynucleotides encoding human collagen II antibodies or fragments thereof, and methods of making and using the foregoing.
Abstract translation: 本发明涉及针对人胶原II的抗体，编码人胶原II抗体或其片段的多肽和多核苷酸，以及制备和使用上述物质的方法。
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公开(公告)号：US20170260282A1
公开(公告)日：2017-09-14
申请号：US15453451
申请日：2017-03-08
Applicant: Janssen Biotech, Inc.
Inventor： Cam Holland , John Kehoe , Linda Snyder , Alejandro Sepulveda , Daniel Villareal
IPC: C07K16/28 , A61K39/00 , A61K39/395 , C07K16/00 , A61K45/06
CPC classification number: C07K16/2878 , A61K39/0011 , A61K39/08 , A61K39/12 , A61K39/39 , A61K39/3955 , A61K45/06 , A61K2039/505 , A61K2039/507 , A61K2039/545 , A61K2039/58 , A61K2039/585 , A61P31/04 , A61P31/20 , C07K16/2818 , C07K16/2827 , C07K16/2866 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/55 , C07K2317/567 , C07K2317/732 , C07K2317/75 , C07K2317/92 , C12N2710/16134 , A61K2300/00
Abstract: Provided herein are antibodies that specifically bind to GITR. Also described are related polynucleotides capable of encoding the provided GITR-specific antibodies or antigen-binding fragments, cells expressing the provided antibodies or antigen-binding fragments, as well as associated vectors and detectably labeled antibodies or antigen-binding fragments. In addition, methods of using the provided antibodies are described. For example, the provided antibodies may be used to enhance an immune response in a subject against cancer.
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公开(公告)号：US20140328837A1
公开(公告)日：2014-11-06
申请号：US14338391
申请日：2014-07-23
Applicant: Janssen Biotech, Inc.
Inventor： Daphne Ann Salick Ryan , John Kehoe , John Wheeler , Chunlin Yang , Abla Creasy
IPC: A61K47/42 , A61K39/395
CPC classification number: A61K47/42 , A61K39/3955 , A61K2039/505 , C07K7/08 , C07K14/525 , C07K16/241 , C07K2317/24 , C07K2317/76 , C07K2317/92
Abstract: We have disclosed affinity peptides toward infliximab. More specifically we have disclosed an affinity biomatrix where the affinity peptide is covalently attached to a biocompatible, biodegradable polymer. The affinity biomatrix is useful in preparing controlled release devices for infliximab.
Abstract translation: 我们已经向英夫利昔单抗公开了亲和肽。 更具体地，我们已经公开了一种亲和力生物基质，其中亲和肽共价连接到生物相容的可生物降解的聚合物上。 亲和力生物基质可用于制备英夫利昔单抗的控制释放装置。
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公开(公告)号：US09944697B2
公开(公告)日：2018-04-17
申请号：US14534525
申请日：2014-11-06
Applicant: Janssen Biotech, Inc.
Inventor： Ken Boakye , Alfred Del Vecchio , John Kehoe , Eilyn Lacy , Lynne Murray , Mary Ryan , Sandra Santulli-Marotto , John Wheeler , Brian Whitaker , Alexey Teplyakov
CPC classification number: C07K16/24 , A61K39/00 , A61K2039/55522 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：US20150125458A1
公开(公告)日：2015-05-07
申请号：US14534525
申请日：2014-11-06
Applicant: Janssen Biotech, Inc.
Inventor： Ken Boakye , Alfred Del Vecchio , John Kehoe , Eilyn Lacy , Lynne Murray , Mary Ryan , Sandra Santulli-Marotto , John Wheeler , Brian Whitaker , Alexey Teplyakov
IPC: C07K16/24
CPC classification number: C07K16/24 , A61K39/00 , A61K2039/55522 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: The present invention relates to antibodies specifically binding CCL17, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
Abstract translation: 本发明涉及特异性结合CCL17的抗体，编码抗体或片段的多核苷酸，以及制备和使用上述物质的方法。
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